Cited by 14Schizophrenia research and treatmentMental Health and PsychiatryPsychoanalysis and Psychopathology Research

Integrative etiopathogenetic models of psychotic disorders: methods, evidence and concepts

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Gaebel, W., Zielasek, J.·2011·Schizophrenia Bulletin

Abstract

Integrative models of the etiopathogesnesis of psychotic disorders are needed since a wealth of information from such diverse fields as neurobiology, psychology, and the social sciences is currently changing the concepts of mental disorders. Several approaches to integrate these streams of information into coherent concepts of psychosis are feasible and will need to be assessed in future experimental studies. Common to these concepts are the notion of psychotic disorders as brain disorders and a polythetic approach in that it is increasingly realized that a multitude of interindividually partially different pathogenetic factors interact in individual persons in a complex fashion resulting in the clinical symptoms of psychosis.

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  1. Grozeva D, Kirov G, Ivanov D, et al. Rare copy number var- iants. A point of rarity in genetic risk for bipolar disorder and schizophrenia. Arch Gen Psychiatry. 2010;67:318-327.
  2. Broyd SJ, Demanuele C, Debener S, Helps SK, James CJ, Sonuga-Barke EJS. Default-mode brain dysfunctions in men- tal disorders: a systematic analysis. Neurosci Biobehav Rev. 2009;33:279-296.
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  4. Andrews G, Goldberg DP, Krueger RF, et al. Exploring the feasibility of a meta-structure for DSM-V and ICD-11: could it improve utility and validity? Psychol Med. 2009; 39:1993-2000.
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Authors
Gaebel, W., & Zielasek, J.
Affiliations
Heinrich Heine University Düsseldorf (DE)
Corresponding author
Gaebel, W.
Venue
Schizophrenia Bulletin
Published
2011-08-22
Volume
37
Issue
suppl 2
Pages
S5-S12
ISSN
  • 0586-7614 (ISSN-L)
  • 1745-1701
OpenAlex
W2125776901
Cited by
14
References
54
Citations by year
2023: 1 · 2021: 1 · 2019: 2 · 2018: 1 · 2017: 2 · 2016: 2 · 2015: 1 · 2014: 1 · 2013: 1 · 2012: 1
FWCI
0.88
Type
journal article
Language
en
Open access
Locations
  • Schizophrenia Bulletin (publishedVersion)
  • Europe PMC (PubMed Central) (publishedVersion)
  • PubMed Central (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Psychiatry and Mental health › Schizophrenia research and treatment
  • Social Sciences › Arts and Humanities › Philosophy › Mental Health and Psychiatry
  • Social Sciences › Psychology › Clinical Psychology › Psychoanalysis and Psychopathology Research
Keywords
psychosis, etiopathogenesis
MeSH terms
Humans, Models, Neurological, Psychotic Disorders, Risk Factors, Schizophrenia, Schizophrenic Psychology, International Classification of Diseases, Diagnostic and Statistical Manual of Mental Disorders

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