Cited by 245Hallucinations in medical conditionsSchizophrenia research and treatmentMental Health and Psychiatry

The DOI matches its Crossref record; 8 of the 8 references it cites were found in a registry or an index.

Quantitative Meta-Analysis on State and Trait Aspects of Auditory Verbal Hallucinations in Schizophrenia

Open access

Kuhn, S., Gallinat, J.·2012·Schizophrenia Bulletin

Open this paper in CoChat — free account Open PDF

Abstract

Auditory verbal hallucinations (AVHs) have a high prevalence in schizophrenic patients. An array of studies have explored the neural correlates of AVHs by means of functional neuroimaging and have associated AVHs with diverse brain regions, some of which have been shown to be involved in speech generation, speech perception, and auditory stimulus processing. We divided these studies into "state" studies comparing periods of presence and absence of AVHs within-subject and "trait" studies comparing patients experiencing AVHs with patients without AVHs or healthy controls during tasks with verbal material. We set out to test the internal consistency and possible dissociations of the neural correlates of AVHs. We used activation likelihood estimation to perform quantitative meta-analyses on brain regions reported in state and trait studies on AVHs to assess significant concordance across studies. State studies were associated with activation in bilateral inferior frontal gyrus, bilateral postcentral gyrus, and left parietal operculum. Trait studies on the other hand showed convergence of decreases in hallucinating subjects in left superior temporal gyrus, left middle temporal gyrus, anterior cingulate cortex, and left premotor cortex activity. Based on the clear dissociation of brain regions that show convergence across state in comparison to trait studies, we conclude that the state of experiencing AVHs is primarily related brain regions that have been implicated in speech production ie, Broca's area, whereas the general trait that makes humans prone to AVHs seems to be related to brain areas involved in auditory stimuli processing and speech perception, ie, auditory cortex.

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Integrity signals

Registry

Crossref · 10.1093/schbul/sbq152

Cites

0 citation errors · 0 not checkable

Statistics

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

A functional neuroanatomy of hallucinations in schizophrenia
Silbersweig, D. A., Stern, E., Frith, C., Cahill, C., Holmes, A., Grootoonk, S., Seaward, J., McKenna, P., Chua, S. E., Schnorr, L., et al. (1995) · Nature · doi:10.1038/378176a0 · Cited by 906
Mapping auditory hallucinations in schizophrenia using functional magnetic resonance imaging
Shergill, S. S., Brammer, M. J., Williams, S. C. R., Murray, R. M., & McGuire, P. K. (2000) · Archives of General Psychiatry · doi:10.1001/archpsyc.57.11.1033 · Cited by 666
Reduced frontotemporal functional connectivity in schizophrenia associated with auditory hallucinations
Lawrie, S. M., Buechel, C., Whalley, H. C., Frith, C. D., Friston, K. J., & Johnstone, E. C. (2002) · Biological Psychiatry · doi:10.1016/s0006-3223(02)01316-1 · Cited by 529
Abnormal monitoring of inner speech: a physiological basis for auditory hallucinations
McGuire, P. K., David, A. S., Murray, R. M., Frackowiak, R. S. J., Frith, C. D., Wright, I., & Silbersweig, D. A. (1995) · The Lancet · doi:10.1016/s0140-6736(95)91435-8 · Cited by 349
Auditory verbal hallucinations predominantly activate the right inferior frontal area
Sommer, I. E. C., Diederen, K. M. J., Blom, J.-D., Willems, A., Kushan, L., Slotema, K., Boks, M. P. M., Daalman, K., Hoek, H. W., Neggers, S. F. W., et al. (2008) · Brain · doi:10.1093/brain/awn251 · Cited by 297
Functional anatomy of inner speech and auditory verbal imagery
McGuire, P. K., Silbersweig, D. A., Murray, R. M., David, A. S., Frackowiak, R. S. J., & Frith, C. D. (1996) · Psychological Medicine · doi:10.1017/s0033291700033699 · Cited by 277
Inner speech models of auditory verbal hallucinations: Evidence from behavioural and neuroimaging studies
Allen, P., Aleman, A., & Mcguire, P. K. (2007) · International Review of Psychiatry · doi:10.1080/09540260701486498 · Cited by 188
Reality of auditory verbal hallucinations
Raij, T. T., Valkonen-Korhonen, M., Holi, M., Therman, S., Lehtonen, J., & Hari, R. (2009) · Brain · doi:10.1093/brain/awp186 · Cited by 95

Show all 8 references

Research works printed but not linked: 43

1991, Schizophrenia Bulletin, 17, 27, 10.1093/schbul/17.1.27 · DOI
Copolov, 2003, Psychiatry research, 122, 139, 10.1016/S0925-4927(02)00121-X · DOI
1999, 22, 615
Lennox, 1999, Lancet, 353, 644, 10.1016/S0140-6736(98)05923-6 · DOI
Lennox, 2000, Psychiatry research, 100, 13, 10.1016/S0165-1781(99)00125-0 · DOI
Shergill, 2001, Journal of Neurology, Neurosurgery & Psychiatry, 71, 688, 10.1136/jnnp.71.5.688 · DOI
Shergill, 2004, The British Journal of Psychiatry, 185, 516, 10.1192/bjp.185.6.516 · DOI
2004, Nature; Physical Science (London), 378, 176
Suzuki, 1993, European archives of psychiatry and clinical neuroscience, 242, 257, 10.1007/BF02190383 · DOI
Woodruff, 1995, Lancet, 346, 1035, 10.1016/S0140-6736(95)91715-2 · DOI
2005, 27, 644, 10.1016/j.neuroimage.2005.04.041 · DOI
Weiss, 1999, Psychiatry research, 92, 61, 10.1016/S0925-4927(99)00041-4 · DOI
Eickhoff, 2009, Human brain mapping, 30, 2907, 10.1002/hbm.20718 · DOI · Paper page
Laird, 2005, Human brain mapping, 25, 155, 10.1002/hbm.20136 · DOI · Paper page
2010, American Journal of Psychiatry, 167, 427, 10.1176/appi.ajp.2009.09040456 · DOI
Hoffman, 2008, The British Journal of Psychiatry, 193, 424, 10.1192/bjp.bp.107.040501 · DOI · Paper page
2007, International review of psychiatry (Abingdon, England), 19, 409
SHERGILL, 2003, The British Journal of Psychiatry, 182, 525, 10.1192/bjp.182.6.525 · DOI
Simons, 2010, Biological psychiatry, 67, 232, 10.1016/j.biopsych.2009.09.007 · DOI · Paper page
Stephane, 2006, Journal of psychiatry & neuroscience : JPN, 31, 396
Zhang, 2008, Acta psychiatrica Scandinavica, 118, 272, 10.1111/j.1600-0447.2008.01243.x · DOI
Zhang, 2008, Journal of psychiatric research, 42, 477, 10.1016/j.jpsychires.2007.04.003 · DOI
2001, 13, S85, 10.1016/S1053-8119(01)91428-4 · DOI
McGuire, 1996, The British Journal of Psychiatry, 169, 148, 10.1192/bjp.169.2.148 · DOI
1997, REVUE DE NEUROPSYC, 7, 281
Blank, 2003, Annals of neurology, 54, 310, 10.1002/ana.10656 · DOI
Rosen, 2000, Neurology, 55, 1883, 10.1212/WNL.55.12.1883 · DOI
Specht, 2008, Neuroscience letters, 442, 180, 10.1016/j.neulet.2008.06.084 · DOI
2004, 42, 1269
Stephane, 2001, Schizophrenia research, 50, 61, 10.1016/S0920-9964(00)00150-X · DOI
2004, Journal of Neurophysiology, 92, 2428, 10.1152/jn.01144.2003 · DOI
2002, 17, 110, 10.1006/nimg.2002.1213 · DOI
2006, 30, 1414, 10.1016/j.neuroimage.2005.11.002 · DOI · Paper page
2001, 13, 684
Barta, 1990, American Journal of Psychiatry, 147, 1457, 10.1176/ajp.147.11.1457 · DOI
2008, PROG NEUROPSYCHOPHARMALCOL BIOL PSYCHIATRY, 32, 72, 10.1016/j.pnpbp.2007.07.014 · DOI
Hoffman, 1997, American Journal of Psychiatry, 154, 1683, 10.1176/ajp.154.12.1683 · DOI
2002, COGN NEUROPSYCHIATRY, 7, 211, 10.1080/13546800244000094 · DOI
Hoffman, 2000, Lancet, 355, 1073, 10.1016/S0140-6736(00)02043-2 · DOI
2000, Archives of General Psychiatry, 60, 49
Posner, 1998, Philosophical Transactions of the Royal Society B: Biological Sciences, 353, 1915, 10.1098/rstb.1998.0344 · DOI
Frith, 1987, Psychological medicine, 17, 631, 10.1017/S0033291700025873 · DOI · Paper page
Spence, 1997, Brain, 120, 1997, 10.1093/brain/120.11.1997 · DOI

Sorted by citations

Inner Speech: Development, Cognitive Functions, Phenomenology, and Neurobiology
Alderson-Day, B., & Fernyhough, C. (2015) · Psychological Bulletin · doi:10.1037/bul0000021 · Cited by 864
“…studies (investigating neural correlates of the occurrence of AVHs in the scanner) show activation of inferior frontal gyrus bilaterally (Kühn & Gallinat, 2012), while speech-processing atypicalities in schizophrenia patients who experience AVHs are also consistent with a model in…”
Result
The neural mechanisms of hallucinations: A quantitative meta-analysis of neuroimaging studies
Zmigrod, L., Garrison, J. R., Carr, J., & Simons, J. S. (2016) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2016.05.037 · Cited by 226
Interaction of language, auditory and memory brain networks in auditory verbal hallucinations
Ćurčić-Blake, B., Ford, J. M., Hubl, D., Orlov, N. D., Sommer, I. E., Waters, F., Allen, P., Jardri, R., Woodruff, P. W., David, O., et al. (2017) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2016.11.002 · Cited by 224
“The STG (left and right) are almost universally active during AVH (Jardri et al., 2011; Kuhn and Gallinat, 2010).”
Background
The “paradoxical” engagement of the primary auditory cortex in patients with auditory verbal hallucinations: A meta-analysis of functional neuroimaging studies
Kompus, K., Westerhausen, R., & Hugdahl, K. (2011) · Neuropsychologia · doi:10.1016/j.neuropsychologia.2011.08.010 · Cited by 286
The auditory steady-state response (ASSR)
O’Donnell, B. F., Vohs, J. L., Krishnan, G. P., Rass, O., Hetrick, W. P., & Morzorati, S. L. (2013) · Supplements to Clinical neurophysiology · doi:10.1016/b978-0-7020-5307-8.00006-5 · Cited by 182
“Auditory hallucinations are a diagnostic criterion for SZ, and patients with auditory hallucinations show altered brain activation in left superior temporal gyrus and middle temporal gyrus compared to nonhallucinating individuals (Kuhn and Gallinat, 2010).”
Background
Hearing voices in the resting brain: A review of intrinsic functional connectivity research on auditory verbal hallucinations
Alderson-Day, B., McCarthy-Jones, S., & Fernyhough, C. (2015) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2015.04.016 · Cited by 165
Are hallucinations due to an imbalance between excitatory and inhibitory influences on the brain?
Jardri, R., Hugdahl, K., Hughes, M., Brunelin, J., Waters, F., Alderson-Day, B., Smailes, D., Sterzer, P., Corlett, P. R., Leptourgos, P., et al. (2016) · Schizophrenia Bulletin · doi:10.1093/schbul/sbw075 · Cited by 157
Structural correlates of auditory hallucinations in schizophrenia: A meta-analysis
Palaniyappan, L. K., Balain, V., Raduà, J., & Liddle, P. F. (2012) · Schizophrenia Research · doi:10.1016/j.schres.2012.01.038 · Cited by 164
Neural correlates of tinnitus duration and Distress: A positron emission tomography study
Schecklmann, M., Landgrebe, M., Poeppl, T., Kreuzer, P., Männer, P., Marienhagen, J., Wack, D., Kleinjung, T., Hajak, G., & Langguth, B. (2013) · Human Brain Mapping · doi:10.1002/hbm.21426 · Cited by 152
“…26; T ¼ 4.0; r ¼ 0.433) and left and right posterior parahippocampal–hippocampal interface (HC), (MNI: x ¼ 24, y ¼ 24, z ¼ 10; T ¼ 3.6; r ¼ 0.434; x ¼ 40, y ¼ 20, z ¼ 6; T ¼ 3.5; r ¼ 0.430). r 236 r reported during verbal auditory hallucinations in schizophrenic patients [Kühn and Gallinat, 2010].”
BackgroundInfluential
Understanding auditory verbal hallucinations: a systematic review of current evidence
Upthegrove, R., Broome, M. R., Caldwell, K., Ives, J., Oyebode, F., & Wood, S. J. (2015) · Acta Psychiatrica Scandinavica · doi:10.1111/acps.12531 · Cited by 160
“trait aspects, Kuhn found the state of experiencing AVHs related to brain regions that have been implicated in speech production, that is, Broca’s area, whereas trait proneness to AVHs seems to be related to areas involved in auditory stimuli processing and speech perception, that is, auditory cortex (149).”
Exploring the ecological validity of thinking on demand: neural correlates of elicited vs. spontaneously occurring inner speech
Hurlburt, R. T., Alderson-Day, B., Kühn, S., & Fernyhough, C. (2016) · PLOS ONE · doi:10.1371/journal.pone.0147932 · Cited by 131
“For example, auditory verbal hallucinations (AVH) have been hypothesized to result from a misattribution of inner speech to an external source [50, 51], a theory that is based largely on the fact that left IFG is activated both in neuroimaging studies of AVH (see meta-analyses in [52, 53]) and in neuroimaging studies…”
Background
Reduced neuronal activity in language-related regions after transcranial magnetic stimulation therapy for auditory verbal hallucinations
Kindler, J., Homan, P., Jann, K., Federspiel, A., Flury, R., Hauf, M., Strik, W., Dierks, T., & Hubl, D. (2013) · Biological Psychiatry · doi:10.1016/j.biopsych.2012.06.019 · Cited by 112
Auditory verbal hallucinations in bipolar disorder (BD) and major depressive disorder (MDD): A systematic review
Toh, W. L., Thomas, N., & Rossell, S. L. (2015) · Journal of Affective Disorders · doi:10.1016/j.jad.2015.05.040 · Cited by 109
“For an overview of neuroimaging research in AVHs, see Kühn and Gallinat (2012) or Palaniyappan et al. (2012).”
Distinct processing of ambiguous speech in people with non-clinical auditory verbal hallucinations
Alderson-Day, B., Lima, C. F., Evans, S., Krishnan, S., Shanmugalingam, P., Fernyhough, C., & Scott, S. K. (2017) · Brain · doi:10.1093/brain/awx206 · Cited by 108
“…in a number of early symptomcapture studies of people hearing voices while being scanned (Shergill et al., 2000), although later meta-analyses have failed to consistently identify this region during the hallucinatory state (Jardri et al., 2011; Kühn and Gallinat, 2012; Zmigrod et al., 2016).”
Background
Positive symptoms associate with cortical thinning in the superior temporal gyrus via the ENIGMA-Schizophrenia consortium
Walton, E., Hibar, D., van Erp, T. V., Potkin, S., Roiz-Santiañez, R., Crespo-Facorro, B., Suárez-Pinilla, P., van Haren, N. V., de Zwarte, S. D., Kahn, R. S., et al. (2017) · Acta Psychiatrica Scandinavica · doi:10.1111/acps.12718 · Cited by 108
“Another similar metaanalysis (20) differentiated between state- and traitbased studies (i.”
Not on speaking terms: hallucinations and structural network disconnectivity in schizophrenia
Ćurĉić‐Blake, B., Nanetti, L., van der Meer, L., Cerliani, L., Renken, R. J., Pijnenborg, G. H. M., & Aleman, A. (2013) · Brain Structure and Function · doi:10.1007/s00429-013-0663-y · Cited by 110
Resting-State Functional Connectivity of the Nucleus Accumbens in Auditory and Visual Hallucinations in Schizophrenia
Rolland, B., Amad, A., Poulet, E., Bordet, R., Vignaud, A., Bation, R., Delmaire, C., Thomas, P., Cottencin, O., & Jardri, R. (2014) · Schizophrenia Bulletin · doi:10.1093/schbul/sbu097 · Cited by 103
The brain's conversation with itself: neural substrates of dialogic inner speech
Alderson-Day, B., Weis, S., McCarthy-Jones, S., Moseley, P., Smailes, D., & Fernyhough, C. (2016) · Social Cognitive and Affective Neuroscience · doi:10.1093/scan/nsv094 · Cited by 94
Individual variation in functional brain connectivity: implications for personalized approaches to psychiatric disease
Finn, E. S., & Constable, R. T. (2016) · Dialogues in Clinical Neuroscience · doi:10.31887/dcns.2016.18.3/efinn · Cited by 101
The role of the primary auditory cortex in the neural mechanism of auditory verbal hallucinations
Kompus, K., Falkenberg, L. E., Bless, J. J., Johnsen, E., Kroken, R. A., Kråkvik, B., Larøi, F., Løberg, E.-M., Vedul-Kjelsås, E., Westerhausen, R., et al. (2013) · Frontiers in Human Neuroscience · doi:10.3389/fnhum.2013.00144 · Cited by 91
“A second meta-analysis by Kühn and Gallinat (2012), which did not find convergence in the PAC utilizing a partly overlapping set of studies, is not directly comparable to Kompus et al. (2011) study, as the included contrasts involved a wide variety of conditions (e.g., auditory imagery, speech…”
Result
Auditory hallucinations: A review of the ERC “VOICE” project
Hugdahl, K. (2015) · World Journal of Psychiatry · doi:10.5498/wjp.v5.i2.193 · Cited by 93
Aberrant salience network functional connectivity in auditory verbal hallucinations: a first episode psychosis sample
Mallikarjun, P. K., Lalousis, P. A., Dunne, T. F., Heinze, K., Reniers, R. L. E. P., Broome, M. R., Farmah, B., Oyebode, F., Wood, S. J., & Upthegrove, R. (2018) · Translational Psychiatry · doi:10.1038/s41398-018-0118-6 · Cited by 91
Auditory Verbal Hallucinations in Schizophrenia From a Levels of Explanation Perspective.
Hugdahl, K., & Sommer, I. (2018) · Schizophrenia bulletin · doi:10.1093/schbul/sbx142 · Cited by 83
Source-based morphometry of gray matter volume in patients with schizophrenia who have persistent auditory verbal hallucinations.
Kubera, K., Sambataro, F., Vasić, N., Wolf, N. D., Frasch, K., Hirjak, D., Thomann, P. A., & Wolf, R. C. (2014) · Progress in Neuro-psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2013.11.015 · Cited by 83
Real-time fMRI neurofeedback to down-regulate superior temporal gyrus activity in patients with schizophrenia and auditory hallucinations: a proof-of-concept study
Orlov, N. D., Giampietro, V., O’Daly, O., Lam, S.-L., Barker, G. J., Rubia, K., McGuire, P. K., Shergill, S. S., & Allen, P. (2018) · Translational Psychiatry · doi:10.1038/s41398-017-0067-5 · Cited by 101
The Concept of Salience Network Dysfunction in Schizophrenia: From Neuroimaging Observations to Therapeutic Opportunities
Palaniyappan, L. K., White, T. P., & Liddle, P. F. (2012) · Current Topics in Medicinal Chemistry · doi:10.2174/156802612805289881 · Cited by 91
Discrimination of Schizophrenia Auditory Hallucinators by Machine Learning of Resting-State Functional MRI
Chyzhyk, D., Graña, M., Öngür, D., & Shinn, A. K. (2015) · International Journal of Neural Systems · doi:10.1142/s0129065715500070 · Cited by 70
Voxel-based gray and white matter morphometry correlates of hallucinations in schizophrenia: The superior temporal gyrus does not stand alone
van Tol, M., van der Meer, L., Bruggeman, R., Modinos, G., Knegtering, H., & Aleman, A. (2014) · NeuroImage Clinical · doi:10.1016/j.nicl.2013.12.008 · Cited by 71
Effects of auditory hallucinations on the mismatch negativity (MMN) in schizophrenia as measured by a modified 'optimal' multi-feature paradigm.
Fisher, D., Grant, B., Smith, D., Borracci, G., Labelle, A., & Knott, V. (2011) · International Journal of Psychophysiology · doi:10.1016/j.ijpsycho.2011.06.018 · Cited by 72
“Similar to previous findings (Kuhn & Gallinat, 2010), this group reported reduced activation of left primary auditory cortex to incoming auditory stimuli in SZ patients prone to AHs, which may reflect competition for resources between internallyand externally-generated auditory events, progressive…”
BackgroundResult
Neural Correlates of Auditory Verbal Hallucinations in Schizophrenia and the Therapeutic Response to Theta-Burst Transcranial Magnetic Stimulation
Chen, X.-G., Ji, G.-J., Zhu, C.-Y., Bai, X., Wang, L., He, K.-L., Gao, Y., Tao, L., Yu, F.-Q., Tian, Y.-H., et al. (2018) · Schizophrenia bulletin · doi:10.1093/schbul/sby054 · Cited by 71
Auditory verbal hallucinations in schizophrenia correlate with P50 gating.
Smith, D., Grant, B., Fisher, D., Borracci, G., Labelle, A., & Knott, V. (2013) · Clinical Neurophysiology · doi:10.1016/j.clinph.2013.02.004 · Cited by 71
“A meta-analysis by Kühn and Gallinat (2012) revealed differences in brain regions during analysis of the ‘‘state’’ and ‘‘trait’’ of hallucinatory experience.”
BackgroundInfluential
Clinical and neurocognitive aspects of hallucinations in Alzheimer’s disease
el Haj, M., Roche, J., Jardri, R., Kapogiannis, D., Gallouj, K., & Antoine, P. (2017) · Neuroscience and Biobehavioral Reviews · doi:10.1016/j.neubiorev.2017.02.021 · Cited by 70
Marking the Perception–Cognition Boundary: The Criterion of Stimulus-Dependence
Beck, J. (2018) · Australasian Journal of Philosophy · doi:10.1080/00048402.2017.1329329 · Cited by 69
The American Psychiatric Association Publishing Textbook of Psychopharmacology
Schatzberg, A., & Nemeroff, C. (2017) · American Psychiatric Association Publishing eBooks · doi:10.1176/appi.books.9781615371624 · Cited by 69
Aberrant resting-state connectivity in non-psychotic individuals with auditory hallucinations
Diederen, K. M. J., Neggers, S. F. W., de Weijer, A. D., van Lutterveld, R., Daalman, K., Eickhoff, S. B., Clos, M., Kahn, R. S., & Sommer, I. E. (2012) · Psychological Medicine · doi:10.1017/s0033291712002541 · Cited by 53
“…the inferior frontal gyri, insula, pre- and postcentral gyri, frontal and parietal operculum, middle and superior temporal gyri, inferior parietal lobule and hippocampus/ parahippocampal region (Sommer et al. 2008b ; Jardri et al. 2010 ; Kuhn & Gallinat, 2010 ; Diederen et al. 2011, 2012).”
BackgroundResult
Auditory verbal hallucinations: neuroimaging and treatment
Bohlken, M., Hugdahl, K., & Sommer, I. (2016) · Psychological Medicine · doi:10.1017/s003329171600115x · Cited by 60
“…studies measuring trait aspects of AVH show that regions including the bilateral ACC), the left superior and middle temporal gyrus and the left premotor cortex are hypoactive in patients with psychosis experiencing AVH during language-related tasks (for a meta-analysis, see Kühn & Gallinat, 2012).”
Targeting treatment-resistant auditory verbal hallucinations in schizophrenia with fMRI-based neurofeedback – exploring different cases of Schizophrenia
Dyck, M. S., Mathiak, K. A., Bergert, S., Sarkheil, P., Koush, Y., Alawi, E. M., Zvyagintsev, M., Gaebler, A. J., Shergill, S. S., & Mathiak, K. (2016) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2016.00037 · Cited by 56
Magnetic Resonance Imaging in Studying Schizophrenia, Negative Symptoms, and the Glutamate System
Gruber, O., Chadha, A. S., & Aach, H. (2014) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2014.00032 · Cited by 55
“A second meta-analysis by Kühn and Gallinat (23) came to the conclusion that a current psychopathological state of experiencing auditory–verbal hallucinations may be associated with abnormal activation of brain regions that are also involved in speech production (e.”
Background
Reduced functional connectivity and asymmetry of the planum temporale in patients with schizophrenia and first-degree relatives
Oertel‐Knöchel, V., Knöchel, C., Matura, S., Prvulovic, D., Linden, D. E. J., & van de Ven, V. G. (2013) · Schizophrenia Research · doi:10.1016/j.schres.2013.04.024 · Cited by 59
“Furthermore, predispositions towards hallucinations (RHS) was significantly associated with left STG activation in first-degree relatives , which supports the hypothesis by (Kuhn and Gallinat, 2012) about trait-related associations between AVH and STG activation.”
Result
Effects of low frequency rTMS treatment on brain networks for inner speech in patients with schizophrenia and auditory verbal hallucinations
Bais, L., Liemburg, E. J., Vercammen, A., Bruggeman, R., Knegtering, H., & Aleman, A. (2017) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2017.04.017 · Cited by 57
“…engagement of a distributed network involved in language processing and verbal memory, including the inferior frontal gyrus, middle/ superior temporal gyri and medial regions such as the hippocampus and insula, when comparing AVH periods to rest (Jardri et al., 2011; Kuhn and Gallinat, 2012).”
Mechanisms Underlying Auditory Hallucinations—Understanding Perception without Stimulus
Tracy, D. K., & Shergill, S. S. (2013) · Brain Sciences · doi:10.3390/brainsci3020642 · Cited by 58
“Kühn and Gallinat [87] recently undertook a meta-analysis of neuroimaging data on state and trait aspects of AVH in schizophrenia: that is those areas whose activation varied within-subjects (hallucinators) depending upon the presence or absence of AVH (state); and those areas whose activation varied between groups of…”
Background
Resting-state functional connectivity in medication-naïve schizophrenia patients with and without auditory verbal hallucinations: A preliminary report.
Chang, X., Collin, G., Xi, Y.-B., Cui, L.-B., Scholtens, L. H., Sommer, I., Wang, H.-N., Yin, H., Kahn, R., & van den Heuvel, M. P. (2017) · Schizophrenia Research · doi:10.1016/j.schres.2017.01.024 · Cited by 51
“org areas) and other regions of the cortex (Jardri et al., 2011; Kompus et al., 2011; Kühn and Gallinat, 2010).”
Linked 4-Way Multimodal Brain Differences in Schizophrenia in a Large Chinese Han Population
Liu, S., Wang, H., Song, M., Lv, L., Cui, Y., Liu, Y., Fan, L.-Z., Zuo, N.-M., Xu, K.-B., Du, Y.-H., et al. (2019) · Schizophrenia bulletin · doi:10.1093/schbul/sby045 · Cited by 50
Repeated measurements of cerebral blood flow in the left superior temporal gyrus reveal tonic hyperactivity in patients with auditory verbal hallucinations: a possible trait marker
Homan, P., Kindler, J., Hauf, M., Walther, S., Hubl, D., & Dierks, T. (2013) · Frontiers in Human Neuroscience · doi:10.3389/fnhum.2013.00304 · Cited by 50
“…experienced AVH) in the temporal lobe, which would then contribute to the small differences that were observed in the within-subject comparison between conditions and to the seemingly decreased activation in hallucinating subjects compared to non-hallucinating subjects (Kuhn and Gallinat, 2012).”
BackgroundResultInfluential
A review of functional and structural neuroimaging studies to investigate the inner speech model of auditory verbal hallucinations in schizophrenia
Barber, L., Reniers, R. L. E. P., & Upthegrove, R. (2021) · Translational Psychiatry · doi:10.1038/s41398-021-01670-7 · Cited by 63
“Furthermore, both Jardri et al. [5] and Kühn and Gallinat [14] used the false discovery rate to correct for multiple comparisons; the more stringent cluster-level FWE correction was used here.”
BackgroundMethodInfluential
Altered Fronto-Temporal Functional Connectivity in Individuals at Ultra-High-Risk of Developing Psychosis
Yoon, Y., Yun, J.-Y., Jung, W., Kang, I.-C. K., Kim, S., Lee, T., Park, H., & Kwon, J. (2015) · PLoS ONE · doi:10.1371/journal.pone.0135347 · Cited by 46
“A meta-analysis revealed that the core regions responsible for hallucinations are the regions related to speech production, whereas an individual’s hallucinatory trait is associated with the speech perception areas [50].”
Background
Nicotine, Auditory Sensory Memory, and sustained Attention in a Human Ketamine Model of Schizophrenia: Moderating Influence of a Hallucinatory Trait
Knott, V., Shah, D., Millar, A., McIntosh, J., Fisher, D., Blais, C., & Ilivitsky, V. (2012) · Frontiers in Pharmacology · doi:10.3389/fphar.2012.00172 · Cited by 44
Reading impairments in schizophrenia relate to individual differences in phonological processing and oculomotor control: Evidence from a gaze-contingent moving window paradigm.
Whitford, V., O'Driscoll, G. A., Pack, C. C., Joober, R., Malla, A., & Titone, D. (2013) · Journal of Experimental Psychology: General · doi:10.1037/a0028062 · Cited by 42
Structure/function interrelationships in patients with schizophrenia who have persistent auditory verbal hallucinations: A multimodal MRI study using parallel ICA
Kubera, K. M., Rashidi, M., Schmitgen, M. M., Barth, A., Hirjak, D., Sambataro, F., Calhoun, V. D., & Wolf, R. C. (2019) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2019.03.007 · Cited by 45
Cerebral blood flow alterations specific to auditory verbal hallucinations in schizophrenia.
Zhuo, C., Zhu, J., Qin, W., Qu, H., Ma, X.-L., & Yu, C.-S. (2017) · The British journal of psychiatry : the journal of mental science · doi:10.1192/bjp.bp.115.174961 · Cited by 42
Cortical and subcortical neuroanatomical signatures of schizotypy in 3004 individuals assessed in a worldwide ENIGMA study
Kirschner, M., Hodzic-Santor, B. H., Antoniades, M., Nenadić, I., Kircher, T. T. J., Krug, A., Meller, T., Grotegerd, D., Fornito, A., Arnatkevičiūtė, A., et al. (2021) · Molecular Psychiatry · doi:10.1038/s41380-021-01359-9 · Cited by 46
“Prior schizotypy studies reported mixed findings, including greater prefrontal [38] or spared OFC thickness [36], and lower frontal grey matter volume [37,”
Meta-analytic Evidence for the Plurality of Mechanisms in Transdiagnostic Structural MRI Studies of Hallucination Status
Rollins, C. P. E., Garrison, J., Simons, J., Rowe, J., O'Callaghan, C., Murray, G., & Suckling, J. (2018) · bioRxiv · doi:10.1016/j.eclinm.2019.01.012 · Cited by 39
“Indeed, AVH in schizophrenia has been associated with increased functional activation in the STG, insula, anterior cingulate, and pre/post central gyrus [21,22], reduced resting connectivity between default mode regions [99], disruptions to the salience network [30], and altered interactions between resting-state netw…”
Background
Neuroimaging of Voice Hearing in Non-Psychotic Individuals: A Mini Review
Diederen, K., van Lutterveld, R., & Sommer, I. (2012) · Frontiers in Human Neuroscience · doi:10.3389/fnhum.2012.00111 · Cited by 39
Monitoring what is real: The effects of modality and action on accuracy and type of reality monitoring error
Garrison, J. R., Bond, R. L., Gibbard, E., Johnson, M. K., & Simons, J. S. (2016) · Cortex · doi:10.1016/j.cortex.2016.06.018 · Cited by 50
“…this proposal comes from fMRI analysis of cortical activation during state studies of both auditory and visual hallucinations (Garrison, 2015; Kühn & Gallinat, 2012), which have identified hallucination-related activation in the respective sensory cortices, and from research observing…”
Background
Noninvasive brain stimulation for the treatment of auditory verbal hallucinations in schizophrenia: methods, effects and challenges
Kubera, K., Barth, A., Hirjak, D., Thomann, P., & Wolf, R. C. (2015) · Frontiers in Systems Neuroscience · doi:10.3389/fnsys.2015.00131 · Cited by 37
“Abnormal activation of the right hemisphere regions such as the inferior frontal gyrus and the postcentral gyrus is a frequently reported finding in patients who experience persistent AVH (Kuhn and Gallinat, 2012).”
Background
Poor supplementary motor area activation differentiates auditory verbal hallucination from imagining the hallucination
Raij, T. T., & Riekki, T. J. J. (2012) · NeuroImage Clinical · doi:10.1016/j.nicl.2012.09.007 · Cited by 38
“Imaging studies that have compared AVHrelated brain activation with non-AVH periods do not typically report SMA activation (Jardri et al., 2011; Allen et al., 2008; Kuhn and Gallinat, 2012).”
BackgroundResultInfluential
Investigation of Heschl's gyrus and planum temporale in patients with schizophrenia and bipolar disorder: A proton magnetic resonance spectroscopy study
Atagün, M. İ., Şıkoğlu, E. M., Can, S. S., Karakaş-Uğurlu, G., Ulusoy-Kaymak, S., Çayköylü, A., Algın, O., Phillips, M. L., Moore, C. M., & Öngür, D. (2014) · Schizophrenia Research · doi:10.1016/j.schres.2014.11.012 · Cited by 33
“Moreover, left superior temporal cortices have been associated with symptom domains such as auditory hallucinations (Dierks et al., 1999; Jardri et al., 2011; Kuhn and Gallinat, 2012; Modinos et al., 2013; Shinn et al., 2013) and thought disorder (Seese et al.”
Background
How much do we know about schizophrenia and how well do we know it? Evidence from the Schizophrenia Library
Matheson, S. L., Shepherd, A. M., & Carr, V. J. (2014) · Psychological Medicine · doi:10.1017/s0033291714000166 · Cited by 42
“Compared with patients without hallucinations, hallucinating patients show decreased activation during verbal tasks in the left superior and middle temporal gyri, anterior cingulate cortex and left premotor cortex (Kuhn & Gallinat, 2012).”
Background
Language abnormalities in schizophrenia: binding core symptoms through contemporary empirical evidence
Chang, X., Zhao, W. D., Kang, J., Xiang, S., Xie, C., Hernández, H. C., Palaniyappan, L. K., & Feng, J. (2022) · Schizophrenia · doi:10.1038/s41537-022-00308-x · Cited by 31
Intra-Regional Glu-GABA vs Inter-Regional Glu-Glu Imbalance: A 1H-MRS Study of the Neurochemistry of Auditory Verbal Hallucinations in Schizophrenia
Hjelmervik, H., Craven, A., Sinceviciute, I., Johnsen, E., Kompus, K., Bless, J., Kroken, R., Løberg, E., Ersland, L., Grüner, R., et al. (2019) · Schizophrenia bulletin · doi:10.1093/schbul/sbz099 · Cited by 33
Alterations of Functional and Structural Networks in Schizophrenia Patients with Auditory Verbal Hallucinations
Zhu, J., Wang, C., Liu, F., Qin, W., Li, J., & Zhuo, C. (2016) · Frontiers in Human Neuroscience · doi:10.3389/fnhum.2016.00114 · Cited by 34
“…white matter integrity (Geoffroy et al., 2014; Wigand et al., 2015), state activation (Jardri et al., 2011; Kompus et al., 2011; Allen et al., 2012; Kuhn and Gallinat, 2012), and resting-state functional connectivity (Hoffman and Hampson, 2011)] related to AVH has been accumulating in recent years.”
Background
A whole-brain neuromark resting-state fMRI analysis of first-episode and early psychosis: Evidence of aberrant cortical-subcortical-cerebellar functional circuitry
Jensen, K. M., Calhoun, V. D., Fu, Z., Yang, K., Faria, A. V., Ishizuka, K., Sawa, A., Andrés-Camazón, P., Coffman, B. A., Seebold, D., et al. (2024) · NeuroImage Clinical · doi:10.1016/j.nicl.2024.103584 · Cited by 25
“Both of these regions are involved in the language network, and as a result, many studies have investigated and identified associations between the IFG, STG, and auditory verbal hallucinations (Jardri et al., 2011; Kompus et al., 2011; Kuhn & Gallinat, 2012; Zhang et al., 2015).”
Background
Auditory Hallucinations as Translational Psychiatry: Evidence from Magnetic Resonance Imaging
Hugdahl, K. (2017) · Balkan Medical Journal · doi:10.4274/balkanmedj.2017.1226 · Cited by 30
“From the “classic” studies by (11,13,15), which were mainly”
Background
Emotional self-other voice processing in schizophrenia and its relationship with hallucinations: ERP evidence.
Pinheiro, A., Rezaii, N., Rauber, A., Nestor, P., Spencer, K., & Niznikiewicz, M. (2017) · Psychophysiology · doi:10.1111/psyp.12880 · Cited by 30
Multivariate Analysis of Structural and Functional Neuroimaging Can Inform Psychiatric Differential Diagnosis
Stoyanov, D., Kandilarova, S., Aryutova, K., Paunova, R., Todeva-Radneva, A., Latypova, A., & Kherif, F. (2020) · Diagnostics · doi:10.3390/diagnostics11010019 · Cited by 28
On “Hearing” Voices and “Seeing” Things: Probing Hallucination Predisposition in a Portuguese Nonclinical Sample with the Launay-Slade Hallucination Scale-Revised
Castiajo, P., & Pinheiro, A. P. (2017) · Frontiers in Psychology · doi:10.3389/fpsyg.2017.01138 · Cited by 28
“…than clinical hallucinations (e.g., de Leede-Smith and Barkus, 2013), the study of this phenomenon in a nonclinical population is particularly advantageous as it avoids confounding effects of medication and hospitalization that are often ascribed to clinical samples (e.g., Kühn and Gallinat, 2010).”
Background
Neurological Soft Signs Predict Auditory Verbal Hallucinations in Patients With Schizophrenia
Wolf, R. C., Rashidi, M., Schmitgen, M. M., Fritze, S., Sambataro, F., Kubera, K. M., & Hirjak, D. (2020) · Schizophrenia Bulletin · doi:10.1093/schbul/sbaa146 · Cited by 27
Neuroimaging auditory verbal hallucinations in schizophrenia patient and healthy populations
Biase, M. A. D., Zhang, F., Lyall, A. E., Kubicki, M. R., Mandl, R. C. W., Sommer, I. E., & Pasternak, O. (2019) · Psychological Medicine · doi:10.1017/s0033291719000205 · Cited by 34
“Magnetic resonance imaging (MRI) studies comparing schizophrenia patients with and without AVH implicate volume and gray matter thickness (GMT) changes in predominantly language-related gray matter areas, such as temporal cortical regions, Broca’s area, and prefrontal regions in the pathology of AVH (Kühn and Gallinat…”
Background
Functional MRI Evaluation of Multiple Neural Networks Underlying Auditory Verbal Hallucinations in Schizophrenia Spectrum Disorders
Thoma, R., Chaze, C., Lewine, J., Calhoun, V., Clark, V., Bustillo, J., Houck, J., Ford, J., Bigelow, R., Wilhelmi, C., et al. (2016) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2016.00039 · Cited by 26
Repetitive transcranial magnetic stimulation in the treatment of auditory hallucinations in schizophrenic patients
Montagne-Larmurier, A., Etard, O., Maiza, O., & Dollfus, S. (2011) · Current Opinion in Psychiatry · doi:10.1097/yco.0b013e32834bd26e · Cited by 26
Translating Neurocognitive Models of Auditory-Verbal Hallucinations into Therapy: Using Real-time fMRI-Neurofeedback to Treat Voices
Fovet, T., Orlov, N. D., Dyck, M., Allen, P., Mathiak, K., & Jardri, R. (2016) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2016.00103 · Cited by 25
“For example, two meta-analyses of AVHs in schizophrenia demonstrated that the human voice sensitive region of the left and right STG is associated with the experience of AVHs (66, 79).”
Background
A Cognitive Neuroscience View of Voice-Processing Abnormalities in Schizophrenia
Conde, T., Gonçalves, Ó. F., & Pinheiro, A. P. (2016) · Harvard Review of Psychiatry · doi:10.1097/hrp.0000000000000082 · Cited by 25
“Temporal cortical areas and emotion-related structures (amygdala, insula, and orbitofrontal cortex) have been previously implicated in the experience of auditory hallucinations.(119,120) The activation pattern of such areas in these studies(117,118) suggests that experiencing AVH engages the same neural resources unde…”
Background
Insights into hallucinations in schizophrenia: Novel treatment approaches
Aleman, A., & Larøi, F. (2011) · Expert Review of Neurotherapeutics · doi:10.1586/ern.11.90 · Cited by 24
Neurocognitive Basis of Schizophrenia: Information Processing Abnormalities and Clues for Treatment
Aleman, A. (2014) · Advances in Neuroscience · doi:10.1155/2014/104920 · Cited by 21
Increased local spontaneous neural activity in the left precuneus specific to auditory verbal hallucinations of schizophrenia
Zhuo, C.-J., Zhu, J.-J., Wang, C.-L., Wang, L.-N., Li, J., & Qin, W. (2016) · Chinese Medical Journal · doi:10.4103/0366-6999.178974 · Cited by 22
Language-Related Neurophysiological Deficits in Schizophrenia
Hirano, S., Spencer, K., Onitsuka, T., & Hirano, Y. (2019) · Clinical EEG and Neuroscience · doi:10.1177/1550059419886686 · Cited by 27
The Etiology of Auditory Hallucinations in Schizophrenia: From Multidimensional Levels
Shao, X., Liao, Y., Gu, L., Chen, W., & Tang, J. (2021) · Frontiers in Neuroscience · doi:10.3389/fnins.2021.755870 · Cited by 21
“Across populations of schizophreniaspectrum disorder, psychotic disorder, and healthy controls, meta-analyses of trait studies revealed that AVHs were frequently related to activations in the left middle and superior temporal gyrus, left postcentral and precentral gyrus, left insula, left hippocampus/parahippocampal r…”
Background
Cerebral blood flow and its connectivity features of auditory verbal hallucinations in schizophrenia: A perfusion study
Cui, L., Chen, G., Xu, Z., Liu, L., Wang, H., Guo, L., Liu, W.-M., Liu, T., Qi, S., Liu, K., et al. (2016) · Psychiatry Research Neuroimaging · doi:10.1016/j.pscychresns.2016.12.006 · Cited by 26
The Static and dynamic functional connectivity characteristics of the left temporoparietal junction region in schizophrenia patients with auditory verbal hallucinations during low-frequency rTMS treatment
Xie, Y.-J., Guan, M.-Z., He, Y., Wang, Z.-H., Ma, Z.-J., Fang, P., & Wang, H.-N. (2023) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2023.1071769 · Cited by 20
“Functional imaging studies have explored the neural correlates of AVH and have suggested that experiencing AVH is primarily involved the language-related network associated with the Broca area, the anterior insula, the inferior frontal gyrus, the middle temporal gyrus, the superior temporal gyrus (4, 49).”
Background
Impact of low-frequency repetitive transcranial magnetic stimulation on functional network connectivity in schizophrenia patients with auditory verbal hallucinations.
Xie, Y.-J., Guan, M.-Z., Cai, Y., Wang, Z.-H., Ma, Z.-J., Fang, P., & Wang, H.-N. (2022) · Psychiatry Research · doi:10.1016/j.psychres.2022.114974 · Cited by 20
Cerebral blood flow changes in schizophrenia patients with auditory verbal hallucinations during low-frequency rTMS treatment
Xie, Y., Guan, M., Wang, Z., Ma, Z., Fang, P., & Wang, H. (2023) · European Archives of Psychiatry and Clinical Neuroscience · doi:10.1007/s00406-023-01624-8 · Cited by 20
“The mixed findings could potentially be attributed to differences in brain activation patterns observed in state (within-subject analysis) and trait (between-subject analysis) studies [42].”
Background
A Computational Assessment of Target Engagement in the Treatment of Auditory Hallucinations with Transcranial Direct Current Stimulation
Lee, W. H., Kennedy, N. I., Bikson, M., & Frangou, S. (2018) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2018.00048 · Cited by 21
“Both of these regions have been associated with increased AVH frequency in patients who experience persistent AVH (44).”
Background
Superior temporal gyrus functional connectivity predicts transcranial direct current stimulation response in Schizophrenia: A machine learning study
Paul, A. K., Bose, A., Kalmady, S. V., Shivakumar, V., Sreeraj, V. S., Parlikar, R. U., Narayanaswamy, J. C., Dursun, S. M., Greenshaw, A. J., Greiner, R., et al. (2022) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2022.923938 · Cited by 24
“Other regions contributing to the tDCS response prediction model include bilateral precentral and postcentral gyri; both these regions show activation (73) and higher activation likelihood estimate during the occurrence of AVH (43, 44).”
Background
Recent findings on neurofeedback training for auditory hallucinations in schizophrenia
Hirano, Y., & Tamura, S. (2021) · Current Opinion in Psychiatry · doi:10.1097/yco.0000000000000693 · Cited by 18
Auditory verbal hallucinations reflect stable auditory attention deficits: a prospective study
Løberg, E., Jørgensen, H. A., Kroken, R., & Johnsen, E. (2015) · Cognitive Neuropsychiatry · doi:10.1080/13546805.2014.977857 · Cited by 18
“The authors suggested that the AVH state was more related to speech production areas, and trait was related more related to auditory and speech perception areas of the brain (Kuhn & Gallinat, 2012).”
Background
Glutamate- and GABA-Modulated Connectivity in Auditory Hallucinations—A Combined Resting State fMRI and MR Spectroscopy Study
Weber, S., Hjelmervik, H., Craven, A., Johnsen, E., Kroken, R., Løberg, E., Ersland, L., Kompus, K., & Hugdahl, K. (2021) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2021.643564 · Cited by 17
“There were Glx effects on left STG connectivity with occipital and postcentral areas and the thalamus, all of which have been associated with hallucinations (3, 31, 32).”
Background
Association of cognitive and P50 suppression deficits in chronic patients with schizophrenia.
Xia, L., Wang, D.-M., Wang, J.-S., Xu, H., Huo, L., Tian, Y., Dai, Q., Wei, S.-C., Wang, W., Zhang, G.-Y., et al. (2020) · Clinical Neurophysiology · doi:10.1016/j.clinph.2019.12.405 · Cited by 17
Abnormal auditory tonotopy in patients with schizophrenia
Doucet, G., Luber, M. J., Balchandani, P., Sommer, I., & Frangou, S. (2019) · npj Schizophrenia · doi:10.1038/s41537-019-0084-x · Cited by 17
The effect of rTMS on auditory hallucinations: clues from an EEG-rTMS study.
van Lutterveld, R., Koops, S., Schutter, D., Geertsema, E., Stam, C., Kahn, R., & Sommer, I. (2012) · Schizophrenia Research · doi:10.1016/j.schres.2012.01.010 · Cited by 17
A working model of neural activity and phenomenal experience in psychosis
Martino, M., & Magioncalda, P. (2024) · Molecular Psychiatry · doi:10.1038/s41380-024-02607-4 · Cited by 14
“…shown by a consistent reduction of activation (and FC) in the superior temporal gyrus/auditory cortex during exteroceptive auditory stimulation [63, 64, 68, 111] (while a de ﬁ cit in the sensory processing of visual stimuli and retinopathy, frequently occurring in schizophrenia, may be associated…”
Regional cerebral blood flow at rest in schizophrenia and major depressive disorder: A functional neuroimaging meta-analysis
Boisvert, M., Lungu, O., Pilon, F., Dumais, A., & Potvin, S. (2023) · Psychiatry Research Neuroimaging · doi:10.1016/j.pscychresns.2023.111720 · Cited by 17
Altered Effective Connectivity in Schizophrenic Patients With Auditory Verbal Hallucinations: A Resting-State fMRI Study With Granger Causality Analysis
Gao, J., Zhang, D., Wang, L., Wang, W., Fan, Y., Tang, M., Zhang, X., Lei, X., Wang, Y., Yang, J., et al. (2020) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2020.00575 · Cited by 17
A Decrease in Hemodynamic Response in the Right Postcentral Cortex Is Associated With Treatment-Resistant Auditory Verbal Hallucinations in Schizophrenia: An NIRS Study
Liang, N., Liu, S., Li, X.-R., Wen, D., Li, Q.-Q., Tong, Y., & Xu, Y. (2022) · Frontiers in Neuroscience · doi:10.3389/fnins.2022.865738 · Cited by 15
“the association of AVH with activation in the postcentral regions related to subvocal speech (Kühn and Gallinat, 2012) and therefore being considered involving inner speech generation (Feinberg, 1978; Shergill et al.”
Background
Altered Coupling of Cerebral Blood Flow and Functional Connectivity Strength in First-Episode Schizophrenia Patients With Auditory Verbal Hallucinations
Chen, J.-L., Xue, K.-K., Yang, M., Wang, K.-F., Xu, Y.-H., Wen, B.-H., Cheng, J.-L., Han, S.-Q., & Wei, Y.-R. (2022) · Frontiers in Neuroscience · doi:10.3389/fnins.2022.821078 · Cited by 15
Gene expression meta-analysis reveals the down-regulation of three GABA receptor subunits in the superior temporal gyrus of patients with schizophrenia
Frajman, A., Maggio, N., Muler, I., Haroutunian, V. H., Katsel, P., Yitzhaky, A., Weiser, M., & Hertzberg, L. (2020) · Schizophrenia Research · doi:10.1016/j.schres.2020.04.027 · Cited by 20
Nicotinic modulation of salience network connectivity and centrality in schizophrenia
Smucny, J., Wylie, K. P., Kronberg, E., Legget, K. T., & Tregellas, J. R. (2017) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2017.01.018 · Cited by 15
“Finally, salience network dysfunction has been linked to all three domains of symptoms in schizophrenia (Kuhn and Gallinat, 2012; Lahti et al., 2006; Manoliu et al., 2013; Palaniyappan et al., 2013).”
Background
Hearing a Voice as one’s own: Two Views of Inner Speech Self-Monitoring Deficits in Schizophrenia
Langland‐Hassan, P. (2015) · Review of Philosophy and Psychology · doi:10.1007/s13164-015-0250-7 · Cited by 13
Varieties of inner speech and creative potential
de Rooij, A. (2022) · Imagination, Cognition and Personality · doi:10.1177/02762366211070999 · Cited by 14
Auditory hallucinations activate language and verbal short-term memory, but not auditory, brain regions
Fuentes-Claramonte, P., Soler-Vidal, J., Salgado-Pineda, P., Garcia-Leon, M., Ramiro, N., Santo-Angles, A., Torres, M. L., Tristany, J., Guerrero-Pedraza, A., Munuera, J., et al. (2021) · Scientific Reports · doi:10.1038/s41598-021-98269-1 · Cited by 14
External speech processing and auditory verbal hallucinations: A systematic review of functional neuroimaging studies.
Richards, S., Hughes, M., Woodward, T., Rossell, S., & Carruthers, S. (2021) · Neuroscience and Biobehavioral Reviews · doi:10.1016/j.neubiorev.2021.09.006 · Cited by 14

Authors: Kuhn, S., & Gallinat, J.
Affiliations: St. Hedwig-Krankenhaus (DE)
Venue: Schizophrenia Bulletin
Publisher: Oxford University Press (OUP)
Published: 2010-12-22
Volume: 38
Issue: 4
Pages: 779-786
ISSN: 0586-7614 (ISSN-L)
1745-1701
DOI: 10.1093/schbul/sbq152
PMC: PMC3406531
OpenAlex: W2159319538
Cited by: 245
References: 53
Citations by year: 2026: 5 · 2025: 11 · 2024: 77 · 2023: 11 · 2022: 13 · 2021: 13 · 2020: 12 · 2019: 10 · 2018: 9 · 2017: 18 · 2016: 18 · 2015: 10 · 2014: 8 · 2013: 12 · 2012: 13
FWCI: 0.70
Type: journal article
Language: en
Open access: bronze
doi.org
Locations: Schizophrenia Bulletin (publishedVersion)
Europe PMC (PubMed Central) (publishedVersion)
PubMed Central (publishedVersion)
PubMed (publishedVersion)
Ghent University Academic Bibliography (Ghent University) (submittedVersion, other-oa)
Max Planck Institute for Plasma Physics (submittedVersion)
MPG.PuRe (Max Planck Society) (submittedVersion)
Funders: Bristol-Myers Squibb
Eli Lilly and Company
AstraZeneca
Bundesministerium für Bildung und Forschung (01GS08159)
Fonds Wetenschappelijk Onderzoek
Vlaamse regering
Cilag
Topics: Life Sciences › Neuroscience › Cognitive Neuroscience › Hallucinations in medical conditions
Health Sciences › Medicine › Psychiatry and Mental health › Schizophrenia research and treatment
Social Sciences › Arts and Humanities › Philosophy › Mental Health and Psychiatry
Keywords: auditory verbal hallucinations, schizophrenia
MeSH terms: Auditory Perception, Brain, Frontal Lobe, Gyrus Cinguli, Hallucinations, Humans, Magnetic Resonance Imaging, Parietal Lobe, Schizophrenia, Speech Perception, Temporal Lobe, Positron-Emission Tomography, Functional Neuroimaging

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Quantitative Meta-Analysis on State and Trait Aspects of Auditory Verbal Hallucinations in Schizophrenia

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Self-check

Citations

Cites

Cited by

Metadata

Record

About these checks