Reading impairments in schizophrenia relate to individual differences in phonological processing and oculomotor control: Evidence from a gaze-contingent moving window paradigm.
Abstract
Language and oculomotor disturbances are 2 of the best replicated findings in schizophrenia. However, few studies have examined skilled reading in schizophrenia (e.g., Arnott, Sali, Copland, 2011; Hayes & O'Grady, 2003; Revheim et al., 2006; E. O. Roberts et al., 2012), and none have examined the contribution of cognitive and motor processes that underlie reading performance. Thus, to evaluate the relationship of linguistic processes and oculomotor control to skilled reading in schizophrenia, 20 individuals with schizophrenia and 16 demographically matched controls were tested using a moving window paradigm (McConkie & Rayner, 1975). Linguistic skills supporting reading (phonological awareness) were assessed with the Comprehensive Test of Phonological Processing (R. K. Wagner, Torgesen, & Rashotte, 1999). Eye movements were assessed during reading tasks and during nonlinguistic tasks tapping basic oculomotor control (prosaccades, smooth pursuit) and executive functions (predictive saccades, antisaccades). Compared with controls, schizophrenia patients exhibited robust oculomotor markers of reading difficulty (e.g., reduced forward saccade amplitude) and were less affected by reductions in window size, indicative of reduced perceptual span. Reduced perceptual span in schizophrenia was associated with deficits in phonological processing and reduced saccade amplitudes. Executive functioning (antisaccade errors) was not related to perceptual span but was related to reading comprehension. These findings suggest that deficits in language, oculomotor control, and cognitive control contribute to skilled reading deficits in schizophrenia. Given that both language and oculomotor dysfunction precede illness onset, reading may provide a sensitive window onto cognitive dysfunction in schizophrenia vulnerability and be an important target for cognitive remediation.
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These passage reading deficits correlate with both behavioral and fMRI-based assessment of visual magnocellular function.
“that correlate with both behavioral (106, 107) and fMRI-based (108) assessment of visual magnocellular function.”
From Sensory Processing Dysfunction in the Personal Experience and Neuronal Machinery of Schizophrenia (2015) · cites this paper as [107]
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Sensory Processing Dysfunction in the Personal Experience and Neuronal Machinery of Schizophrenia
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Chapter 1. Bilingualism, executive control, and eye movement measures of reading
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Self-citationExecutive functioning predicts development of reading skill and perceptual span seven years later
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Automatic Schizophrenia Detection Using Multimodality Media via a Text Reading Task
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Visual expertise for print in schizophrenia: Analysis of the N170 component
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Agency of Subjects and Eye Movements in Schizophrenia Spectrum Disorders
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Self-citation
- Authors
- Whitford, V., O'Driscoll, G. A., Pack, C. C., Joober, R., Malla, A., & Titone, D.
- Affiliations
- Centre for Research on Brain Language and Music (CA)
- Montreal Neurological Institute and Hospital (CA)
- McGill University (CA)
- Venue
- Journal of Experimental Psychology: General
- Published
- 2013-02
- Volume
- 142
- Issue
- 1
- Pages
- 57-75
- ISSN
- 0096-3445 (ISSN-L)
- 1939-2222
- OpenAlex
- W2147519145
- Cited by
- 42
- References
- 160
- Citations by year
- 2026: 1 · 2024: 3 · 2023: 3 · 2022: 3 · 2021: 4 · 2020: 2 · 2019: 1 · 2018: 2 · 2017: 4 · 2016: 8 · 2015: 2 · 2014: 8 · 2012: 1
- FWCI
- 2.51
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of Experimental Psychology General (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Canada Research Chairs Program
- Stairs Memorial Foundation Fund
- EJLB Foundation
- Natural Sciences and Engineering Research Council (341534-07, 204609);)
- Sponsor name not included
- Centre for Research on Brain, Language and Music
- Topics
- Health Sciences › Medicine › Psychiatry and Mental health › Schizophrenia research and treatment
- Social Sciences › Psychology › Developmental and Educational Psychology › Reading and Literacy Development
- Life Sciences › Neuroscience › Cognitive Neuroscience › Neurobiology of Language and Bilingualism
- Keywords
- schizophrenia, reading disorders, phonological processing, oculomotor control, perceptual span, saccade amplitude, antisaccades, prosaccades, smooth pursuit eye movements, executive function, reading comprehension, cognitive remediation, language deficits
- MeSH terms
- Adult, Eye Movements, Female, Humans, Individuality, Male, Reading, Schizophrenia, Visual Perception
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
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