Cited by 42Schizophrenia research and treatmentReading and Literacy DevelopmentNeurobiology of Language and Bilingualism

Reading impairments in schizophrenia relate to individual differences in phonological processing and oculomotor control: Evidence from a gaze-contingent moving window paradigm.

Whitford, Veronica, O'Driscoll, Gillian A., Pack, Christopher C., Joober, Ridha, Malla, Ashok, Titone, Debra·2013·Journal of Experimental Psychology: General

Abstract

Language and oculomotor disturbances are 2 of the best replicated findings in schizophrenia. However, few studies have examined skilled reading in schizophrenia (e.g., Arnott, Sali, Copland, 2011; Hayes & O'Grady, 2003; Revheim et al., 2006; E. O. Roberts et al., 2012), and none have examined the contribution of cognitive and motor processes that underlie reading performance. Thus, to evaluate the relationship of linguistic processes and oculomotor control to skilled reading in schizophrenia, 20 individuals with schizophrenia and 16 demographically matched controls were tested using a moving window paradigm (McConkie & Rayner, 1975). Linguistic skills supporting reading (phonological awareness) were assessed with the Comprehensive Test of Phonological Processing (R. K. Wagner, Torgesen, & Rashotte, 1999). Eye movements were assessed during reading tasks and during nonlinguistic tasks tapping basic oculomotor control (prosaccades, smooth pursuit) and executive functions (predictive saccades, antisaccades). Compared with controls, schizophrenia patients exhibited robust oculomotor markers of reading difficulty (e.g., reduced forward saccade amplitude) and were less affected by reductions in window size, indicative of reduced perceptual span. Reduced perceptual span in schizophrenia was associated with deficits in phonological processing and reduced saccade amplitudes. Executive functioning (antisaccade errors) was not related to perceptual span but was related to reading comprehension. These findings suggest that deficits in language, oculomotor control, and cognitive control contribute to skilled reading deficits in schizophrenia. Given that both language and oculomotor dysfunction precede illness onset, reading may provide a sensitive window onto cognitive dysfunction in schizophrenia vulnerability and be an important target for cognitive remediation.

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Crossref · 10.1037/a0028062

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Authors
Whitford, V., O'Driscoll, G. A., Pack, C. C., Joober, R., Malla, A., & Titone, D.
Affiliations
  • Centre for Research on Brain Language and Music (CA)
  • Montreal Neurological Institute and Hospital (CA)
  • McGill University (CA)
Venue
Journal of Experimental Psychology: General
Published
2013-02
Volume
142
Issue
1
Pages
57-75
ISSN
  • 0096-3445 (ISSN-L)
  • 1939-2222
OpenAlex
W2147519145
Cited by
42
References
160
Citations by year
2026: 1 · 2024: 3 · 2023: 3 · 2022: 3 · 2021: 4 · 2020: 2 · 2019: 1 · 2018: 2 · 2017: 4 · 2016: 8 · 2015: 2 · 2014: 8 · 2012: 1
FWCI
2.51
Type
journal article
Language
en
Open access
closed
Locations
  • Journal of Experimental Psychology General (publishedVersion)
  • PubMed (publishedVersion)
Funders
  • Canada Research Chairs Program
  • Stairs Memorial Foundation Fund
  • EJLB Foundation
  • Natural Sciences and Engineering Research Council (341534-07, 204609);)
  • Sponsor name not included
  • Centre for Research on Brain, Language and Music
Topics
  • Health Sciences › Medicine › Psychiatry and Mental health › Schizophrenia research and treatment
  • Social Sciences › Psychology › Developmental and Educational Psychology › Reading and Literacy Development
  • Life Sciences › Neuroscience › Cognitive Neuroscience › Neurobiology of Language and Bilingualism
Keywords
schizophrenia, reading disorders, phonological processing, oculomotor control, perceptual span, saccade amplitude, antisaccades, prosaccades, smooth pursuit eye movements, executive function, reading comprehension, cognitive remediation, language deficits
MeSH terms
Adult, Eye Movements, Female, Humans, Individuality, Male, Reading, Schizophrenia, Visual Perception

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