Role of the β‐amyloid protein in Alzheimer's disease

Diffusible, nonfibrillar ligands derived from Aβ _1–42 are potent central nervous system neurotoxins

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Neuropathological alterations in Alzheimer disease

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Identification of the major Aβ1–42-degrading catabolic pathway in brain parenchyma: Suppression leads to biochemical and pathological deposition

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Involvement of Caspases in Proteolytic Cleavage of Alzheimer’s Amyloid-β Precursor Protein and Amyloidogenic Aβ Peptide Formation

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Molecular mechanisms of neurodegeneration in Alzheimer's disease

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Scavenger receptor-mediated adhesion of microglia to β-amyloid fibrils

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Identification of amyloid plaques in retinas from Alzheimer's patients and noninvasive in vivo optical imaging of retinal plaques in a mouse model

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Microglia, neuroinflammation, and beta-amyloid protein in Alzheimer’s disease

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A metalloprotease–disintegrin, MDC9/meltrin‐γ/ADAM9 and PKCδ are involved in TPA‐induced ectodomain shedding of membrane‐anchored heparin‐binding EGF‐like growth factor

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Alzheimer's disease and oxidative stress: implications for novel therapeutic approaches

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Abnormal accumulation of NACP/alpha-synuclein in neurodegenerative disorders.

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Diverse Cell Surface Protein Ectodomains Are Shed by a System Sensitive to Metalloprotease Inhibitors

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Detection of single amyloid β-protein aggregates in the cerebrospinal fluid of Alzheimer's patients by fluorescence correlation spectroscopy

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Alzheimer’s-related endosome dysfunction in Down syndrome is Aβ-independent but requires APP and is reversed by BACE-1 inhibition

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Oxidative stress and β-amyloid protein in Alzheimer’s disease

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Engineered nanoparticles for biomolecular imaging

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Alpha‐synuclein in Lewy Body Disease and Alzheimer's Disease

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Mesenchymal stem cells enhance autophagy and increase β-amyloid clearance in Alzheimer disease models

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Pathogenesis of synaptic degeneration in Alzheimer's disease and Lewy body disease

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Extracellular tau is toxic to neuronal cells

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Immune reactive cells in senile plaques and cognitive decline in Alzheimer’s disease

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A small‐molecule enhancer of autophagy decreases levels of Aβ and APP‐CTF via Atg5‐dependent autophagy pathway

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Progressive accumulation of amyloid‐ β oligomers in Alzheimer’s disease and in amyloid precursor protein transgenic mice is accompanied by selective alterations in synaptic scaffold proteins

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In situ characterization of beta-amyloid in Alzheimer's diseased tissue by synchrotron Fourier transform infrared microspectroscopy

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Neuroprotective properties of resveratrol and derivatives

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Heart Failure and Protein Quality Control

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Neuronal overexpression of APPL, the Drosophila homologue of the amyloid precursor protein (APP), disrupts axonal transport

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Amyloid β Protein-(1–42) Forms Calcium-permeable, Zn2+-sensitive Channel

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Roles of AMP-activated Protein Kinase in Alzheimer’s Disease

Cai, Z., Yan, L., Li, K., Quazi, S. H., & Zhao, B. (2012) · NeuroMolecular Medicine · doi:10.1007/s12017-012-8173-2 · Cited by 191 · see citing works

Immunohistochemical and subcellular localization of parkin protein: Absence of protein in autosomal recessive juvenile parkinsonism patients

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Amyloid-Peptide Vaccinations Reduce β-Amyloid Plaques but Exacerbate Vascular Deposition and Inflammation in the Retina of Alzheimer’s Transgenic Mice

Liu, B., Rasool, S., Yang, Z., Glabe, C. G., Schreiber, S. S., Ge, J., & Tan, Z. (2009) · The American Journal of Pathology · doi:10.2353/ajpath.2009.090159 · Cited by 182 · see citing works

Actin dynamics and cofilin‐actin rods in alzheimer disease

Bamburg, J. R., & Bernstein, B. W. (2016) · Cytoskeleton · doi:10.1002/cm.21282 · Cited by 181 · see citing works

Interaction of the Receptor for Advanced Glycation End Products (RAGE) with Transthyretin Triggers Nuclear Transcription Factor kB (NF-kB) Activation

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Cytoskeletal pathologies of Alzheimer disease

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The mitochondria-targeted antioxidant MitoQ extends lifespan and improves healthspan of a transgenic Caenorhabditis elegans model of Alzheimer disease

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Distribution of Cystine/Glutamate Exchange Transporter, System xc−, in the Mouse Brain

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Green tea catechins as a BACE1 (β-Secretase) inhibitor

Jeon, S.-Y., Bae, K., Seong, Y.-H., & Song, K. (2003) · Bioorganic & Medicinal Chemistry Letters · doi:10.1016/j.bmcl.2003.09.018 · Cited by 168 · see citing works

Imaging beta amyloid aggregation and iron accumulation in Alzheimer's disease using quantitative susceptibility mapping MRI

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Disrupting β-Amyloid Aggregation for Alzheimer Disease Treatment

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Chronic Intermittent Hypoxia/Reoxygenation Facilitate Amyloid-β Generation in Mice

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Microglia, Scavenger Receptors, and the Pathogenesis of Alzheimer’s Disease

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Amyloid β Protein (1−40) Forms Calcium-Permeable, Zn 2+ -Sensitive Channel in Reconstituted Lipid Vesicles ,

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Mesenchymal Stem Cells Increase Hippocampal Neurogenesis and Neuronal Differentiation by Enhancing the Wnt Signaling Pathway in an Alzheimer's Disease Model

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Roles of Glycogen Synthase Kinase 3 in Alzheimer’s Disease

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Inhibitory potential of nitrogen, oxygen and sulfur containing heterocyclic scaffolds against acetylcholinesterase and butyrylcholinesterase

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Alzheimer’s Disease as Proteolytic Disorders: Anabolism and Catabolism of β-Amyloid

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Abnormal Glutamate Transport Function in Mutant Amyloid Precursor Protein Transgenic Mice

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Diffuse Plaques Contain C-terminal Aβ42and not Aβ40: Evidence From Cats and Dogs

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Characterization of Alternative Isoforms and Inclusion Body of the TAR DNA-binding Protein-43

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A Novel γ-Secretase Assay Based on Detection of the Putative C-terminal Fragment-γ of Amyloid β Protein Precursor

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Mammalian target of rapamycin: A valid therapeutic target through the autophagy pathway for alzheimer's disease?

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β-Secretase-Cleaved Amyloid Precursor Protein Accumulates at Actin Inclusions Induced in Neurons by Stress or Amyloid β: A Feedforward Mechanism for Alzheimer's Disease

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Vasoactive effects of A<i>β</i>in isolated human cerebrovessels and in a transgenic mouse model of Alzheimer's disease: Role of inflammation

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Cholinergic activity and amyloid precursor protein metabolism

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Nuclear receptors as therapeutic targets for Alzheimer's disease

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Metformin activation of AMPK-dependent pathways is neuroprotective in human neural stem cells against Amyloid-beta-induced mitochondrial dysfunction

Chiang, M., Cheng, Y., Chen, S., Yen, C., & Huang, R. (2016) · Experimental Cell Research · doi:10.1016/j.yexcr.2016.08.013 · Cited by 123 · see citing works

Telomere Shortening and Alzheimer’s Disease

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Role of ERAB/l-3-Hydroxyacyl-coenzyme A Dehydrogenase Type II Activity in Aβ-induced Cytotoxicity

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Synapses and Dendritic Spines as Pathogenic Targets in Alzheimer’s Disease

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Amyloid Precursor Protein Is Trafficked and Secreted via Synaptic Vesicles

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β-Secretase(BACE1) inhibitors from pomegranate (Punica granatum) husk

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Preferential accumulation of Aβ(1−42) on gel phase domains of lipid bilayers: An AFM and fluorescence study

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Advances in development of fluorescent probes for detecting amyloid-β aggregates

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Amyloid beta dimers/trimers potently induce cofilin-actin rods that are inhibited by maintaining cofilin-phosphorylation

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Fast anterograde transport of Herpes Simplex Virus: Role for the amyloid precursor protein of Alzheimer's disease

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Upregulation of BACE1 and β-Amyloid Protein Mediated by Chronic Cerebral Hypoperfusion Contributes to Cognitive Impairment and Pathogenesis of Alzheimer’s Disease

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Anti-Aβ1–11 Antibody Binds to Different β-Amyloid Species, Inhibits Fibril Formation, and Disaggregates Preformed Fibrils but Not the Most Toxic Oligomers

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From differentiation to proliferation: The secretory amyloid precursor protein as a local mediator of growth in thyroid epithelial cells

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New polyphenols active on β-amyloid aggregation

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Alzheimer's and prion diseases: distinct pathologies, common proteolytic denominators

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Role of Synucleins in Alzheimer’s Disease

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Effect of graphene oxide on the conformational transitions of amyloid beta peptide: A molecular dynamics simulation study

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Alzheimer Amyloid Protein Precursor Is Localized in Nerve Terminal Preparations to Rab5-containing Vesicular Organelles Distinct from Those Implicated in the Synaptic Vesicle Pathway

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A damaged microcirculation contributes to neuronal cell death in Alzheimer’s disease☆

Grammas, P. (2000) · Neurobiology of Aging · doi:10.1016/s0197-4580(00)00102-0 · Cited by 81 · see citing works

β-secretase (BACE1)-inhibiting stilbenoids from Smilax Rhizoma

Jeon, S. Y., Kwon, S.-H., Seong, Y. H., Bae, K., Hur, J.-M., Lee, Y.-Y., Suh, D., & Song, K. S. (2006) · Phytomedicine · doi:10.1016/j.phymed.2006.09.003 · Cited by 81 · see citing works

Opioid System and Alzheimer’s Disease

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A possible role for the Alzheimer amyloid precursor protein in the regulation of epidermal basal cell proliferation

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Amyloid beta protein-induced zinc sequestration leads to synaptic loss via dysregulation of the ProSAP2/Shank3 scaffold

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Association between the TNFα‐308 A/G polymorphism and the onset‐age of Alzheimer disease

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Alzheimer's Disease: Recent Advances and Future Perspectives

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Disrupted intracellular calcium regulates BACE1 gene expression via nuclear factor of activated T cells 1 (NFAT 1) signaling

Cho, H. J., Jin, S. M., Youn, H., Huh, K., & Mook‐Jung, I. (2007) · Aging Cell · doi:10.1111/j.1474-9726.2007.00360.x · Cited by 71 · see citing works

Genetic polymorphism of cathepsin D is strongly associated with the risk for developing sporadic Alzheimer's disease

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Mechanisms of the Beneficial Effects of Exercise on Brain-Derived Neurotrophic Factor Expression in Alzheimer’s Disease

Jaberi, S., & Fahnestock, M. L. (2023) · Biomolecules · doi:10.3390/biom13111577 · Cited by 74 · see citing works

N-Methyl- -Aspartate Receptor Antagonist MK-801 and Radical Scavengers Protect Cholinergic Nucleus Basalis Neurons against β-Amyloid Neurotoxicity

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Role of Ionizing Radiation in Neurodegenerative Diseases

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