Neuroanatomical substrata of amusement and sadness: A PET activation study using film stimuli
Abstract
The aim of the present study was to explore the neuroanatomical substrata of film-induced amusement and sadness, aiming at maximal reliability by using strict statistics. Film-induced changes in regional cerebral blood flow (rCBF) were measured using positron emission tomography and [15O]water. It appeared that many brain regions were involved similarly and symmetrically in both emotions. Activation of the occipitotemporal and anterior temporal cortex and cerebellum during both emotions agreed well with the earlier findings. Contrary to some earlier studies, the posterior cingulate gyrus and some frontal areas were deactivated in both emotions. The strict explorative analysis did not reveal activations in the limbic or subcorticai structures seen in some earlier studies. However, an additional analysis restricted to the subcortical and limbic system structures revealed bilateral activation of the amygdala in both target emotions. The outcomes of imaginal studies of emotions seem to be largely dependent on the conservativeness of the statistical analysis and very likely also on the method of emotion induction.
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Several cognitive and social deficits observed in autism have also been described in individuals with agenesis of the corpus callosum.
“Several cognitive and social deficits observed in autism have also been described in individuals with agenesis of the CC, although not all individuals with these deficits meet full DSM-IV-TR criteria for autistic disorder.”
From A Meta-Analysis of the Corpus Callosum in Autism (2009) · cites this paper as [59]
The results are consistent with evidence from investigations of individuals with agenesis of the corpus callosum.
“Results reported here are consistent with evidence from investigations examining individuals with agenesis of the CC, pointing to the role that this structure plays in complex brain functions.”
From A Meta-Analysis of the Corpus Callosum in Autism (2009) · cites this paper as [59]
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- Authors
- Aalto, S., Näätänen, P., Wallius, E., Metsähonkala, L., Stenman, H., Niemi, P. M., & Karlsson, H.
- Affiliations
- University of Turku (FI)
- Venue
- Neuroreport
- Published
- 2002-01
- Volume
- 13
- Issue
- 1
- Pages
- 67-73
- ISSN
- 0959-4965 (ISSN-L)
- OpenAlex
- W2015600449
- Cited by
- 68
- References
- 21
- Citations by year
- 2024: 1 · 2021: 1 · 2020: 1 · 2018: 5 · 2017: 2 · 2016: 2 · 2015: 2 · 2014: 3 · 2013: 4 · 2012: 4
- FWCI
- 2.69
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Neuroreport (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Neuroscience › Cognitive Neuroscience › Neural and Behavioral Psychology Studies
- Life Sciences › Neuroscience › Cognitive Neuroscience › Aesthetic Perception and Analysis
- Social Sciences › Arts and Humanities › Literature and Literary Theory › Media Influence and Health
- Keywords
- amusements, sadness, regional cerebral blood flow, brain activation, amygdala, posterior cingulate cortex, occipitotemporal cortex, anterior temporal cortex, cerebellum, limbic system, emotion induction
- MeSH terms
- Adult, Amygdala, Brain, Brain Mapping, Cerebrovascular Circulation, Emotions, Female, Humans, Middle Aged, Tomography, Emission-Computed
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