Drug treatment outcomes for adolescents with comorbid mental and substance use disorders
Abstract
This study compared the pretreatment characteristics and posttreatment outcomes of substance-abusing adolescents with and without comorbid mental disorders in the Drug Abuse Treatment Outcome Studies for Adolescents. Subjects (N = 992) were sampled from 23 adolescent drug treatment programs across three modalities (residential, short-term inpatient, outpatient drug-free). Nearly two thirds (64%) of the sample had at least one comorbid mental disorder, most often conduct disorder. Comorbid youth were more likely to be drug or alcohol dependent and had more problems with family, school, and criminal involvement. Although comorbid youth reduced their drug use and other problem behaviors after treatment, they were more likely to use marijuana and hallucinogens, and to engage in illegal acts in the 12 months after treatment, as compared with the noncomorbid adolescents. Integrated treatment protocols need to be implemented within drug treatment programs in order to improve the outcomes of adolescents with comorbid substance use and mental disorders.
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Comorbid conditions appear to be a critical predictor of illicit drug use treatment outcomes.
“Comorbid conditions appear to be a critical predictor of illicit drug use treatment outcomes (Grella et al., 2001), perhaps because treatment may not sufficiently address comorbid conditions, leaving youth with unresolved mental health symptoms following treatment discharge.”
From Influences of victimization and comorbid conditions on latency to illicit drug use among adolescents and young adults (2020) · cites this paper as Grella et al., 2001
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- Authors
- GRELLA, C. E., HSER, Y.-I., JOSHI, V., & ROUNDS-BRYANT, J.
- Affiliations
- University of California, Los Angeles (US)
- Venue
- The Journal of Nervous and Mental Disease
- Published
- 2001-06
- Volume
- 189
- Issue
- 6
- Pages
- 384-392
- ISSN
- 0022-3018 (ISSN-L)
- OpenAlex
- W2064120012
- Cited by
- 379
- References
- 30
- Citations by year
- 2026: 3 · 2025: 1 · 2024: 6 · 2023: 10 · 2022: 7 · 2021: 10 · 2020: 13 · 2019: 13 · 2018: 10 · 2017: 20 · 2016: 19 · 2015: 15 · 2014: 22 · 2013: 22 · 2012: 15
- FWCI
- 10.89
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- The Journal of Nervous and Mental Disease (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Institutes of Health (5u01da010378-05)
- National Institute on Drug Abuse (K02-DA00139, U01-DA10378, K02DA000139)
- Topics
- Health Sciences › Medicine › Epidemiology › Substance Abuse Treatment and Outcomes
- Social Sciences › Psychology › Clinical Psychology › Child and Adolescent Psychosocial and Emotional Development
- Social Sciences › Psychology › Social Psychology › Mental Health Treatment and Access
- Keywords
- adolescent substance use disorders, comorbid mental disorders, conduct disorder, integrated treatment, residential treatment, outpatient care, cannabis use, hallucinogen use
- MeSH terms
- Adolescent, Age Factors, Ambulatory Care, Mental Disorders, Black or African American, Child, Combined Modality Therapy, Female, Follow-Up Studies, Health Services Research, Hospitalization, Humans, Male, Prospective Studies, Residential Treatment, Severity of Illness Index, United States, Comorbidity, Multivariate Analysis, Substance Abuse Treatment Centers, Treatment Outcome, Diagnosis, Dual (Psychiatry), Substance-Related Disorders, White People
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