Cited by 125Attention Deficit Hyperactivity DisorderPharmaceutical studies and practicesPharmacology and Obesity Treatment

The DOI matches its Crossref record; 41 of the 41 references it cites were found in a registry or an index.

Does Prolonged Therapy With a Long-Acting Stimulant Suppress Growth in Children With ADHD?

SPENCER, THOMAS J., FARAONE, STEPHEN V., BIEDERMAN, JOSEPH, LERNER, MARC, COOPER, KIMBERLY M., ZIMMERMAN, BRENDA·2006·Journal of the American Academy of Child & Adolescent Psychiatry

DOI 10.1097/01.chi.0000205710.01690.d4

Open this paper in CoChat — free account

Abstract

Objective To investigate whether prolonged therapy with a long-acting stimulant affects growth in children with attention-deficit/hyperactivity disorder (ADHD).Method One hundred seventy-eight children ages 6 to 13 years received OROS methylphenidate (OROS MPH, CONCERTA) for at least 21 months. Height and weight were measured monthly during the first year and every 3 months thereafter.Results At baseline, subjects were approximately the expected height for their age and somewhat heavier than expected. Subjects gained height steadily throughout the study and were on average 0.23 cm less than expected at month 21. Weight did not increase and BMI decreased slightly in the first 4 months. Thereafter, weight Z score and BMI Z score remained relatively constant and children were on average 1.23 kg less than expected at month 21. Previous stimulant therapy tended to be associated with a smaller decrease in Z score during the study compared with no previous stimulant therapy. Drug holidays did not significantly affect growth.Conclusions The effects of prolonged OROS MPH therapy on growth were clinically insignificant and limited to slight decreases in weight during the first months of therapy. Drug holidays did not reduce any impact on growth and are thus of questionable utility for limiting potential effects of treatment on growth.

Integrity signals

Registry

Crossref · 10.1097/01.chi.0000205710.01690.d4

Cites

41 of 41 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

The Adolescent Outcome of Hyperactive Children Diagnosed by Research Criteria: I. An 8-Year Prospective Follow-up Study
BARKLEY, R. A., FISCHER, M., EDELBROCK, C. S., & SMALLISH, L. (1990) · Journal of the American Academy of Child & Adolescent Psychiatry · doi:10.1097/00004583-199007000-00007 · Cited by 1,507
Classification and definition of protein-calorie malnutrition.
Waterlow, J. C. (1972) · BMJ · doi:10.1136/bmj.3.5826.566 · Cited by 999
Practice Parameter for the Use of Stimulant Medications in the Treatment of Children, Adolescents, and Adults
Greenhill, L. L., Pliszka, S., & Dulcan, M. K. (2002) · Journal of the American Academy of Child & Adolescent Psychiatry · doi:10.1097/00004583-200202001-00003 · Cited by 927
Adult psychiatric status of hyperactive boys grown up
Mannuzza, S., Klein, R. G., Bessler, A., Malloy, P., & LaPadula, M. (1998) · American Journal of Psychiatry · doi:10.1176/ajp.155.4.493 · Cited by 769
Clinical practice guideline: treatment of the school-aged child with attention-deficit/hyperactivity disorder.
Attention-Deficit, S. O., & Disorder, H. (2001) · Pediatrics · doi:10.1542/peds.108.4.1033 · Cited by 636
Hyperactive Boys Almost Grown Up: V. Replication of Psychiatric Status
Mannuzza, S. (1991) · Archives of General Psychiatry · doi:10.1001/archpsyc.1991.01810250079012 · Cited by 549
Predictors of Persistence and Remission of ADHD into Adolescence: Results from a Four-Year Prospective Follow-up Study
BIEDERMAN, J., FARAONE, S., MILBERGER, S., CURTIS, S., CHEN, L., MARRS, A., OUELLETTE, C., MOORE, P., & SPENCER, T. (1996) · Journal of the American Academy of Child & Adolescent Psychiatry · doi:10.1097/00004583-199603000-00016 · Cited by 510
Self-citation
Randomized, Controlled Trial of OROS Methylphenidate Once a Day in Children With Attention-Deficit/Hyperactivity Disorder
Wolraich, M. L., Greenhill, L. L., Pelham, W., Swanson, J., Wilens, T., Palumbo, D., Atkins, M., McBurnett, K., Bukstein, O., August, G., et al. (2001) · Pediatrics · doi:10.1542/peds.108.4.883 · Cited by 502
Untitled work
(2001) · Europe PMC (PubMed Central) · Cited by 393
National Institute of Mental Health Multimodal Treatment Study of ADHD Follow-up: Changes in Effectiveness and Growth After the End of Treatment
MTA Cooperative Group (2004) · PEDIATRICS · doi:10.1542/peds.113.4.762 · Cited by 384

Show all 41 references

Research works printed but not linked: 2

Baren, 2000, Lack of effect of different breakfast conditions on the pharmacokinetics and efficacy of OROS methylphenidate HCl extended-release tablets in children with ADHD, Pediatr Res, 47, 23A
Swanson, 2000, Initiating CONCERTA (OROS methylphenidate HCI) qd in children with attention-deficit hyperactivity disorder, J Clin Res, 3, 59

Sorted by citations

European guidelines on managing adverse effects of medication for ADHD
(for the European Guidelines Group), Graham, J., Banaschewski, T., Buitelaar, J., Coghill, D., Danckaerts, M., Dittmann, R. W., Döpfner, M., Hamilton, R., Hollis, C., et al. (2011) · European Child & Adolescent Psychiatry · doi:10.1007/s00787-010-0140-6 · Cited by 374
Effects of Stimulant Medication on Growth Rates Across 3 Years in the MTA Follow-up
SWANSON, J. M., ELLIOTT, G. R., GREENHILL, L. L., WIGAL, T., ARNOLD, L. E., VITIELLO, B., HECHTMAN, L., EPSTEIN, J. N., PELHAM, W. E., ABIKOFF, H. B., et al. (2007) · Journal of the American Academy of Child & Adolescent Psychiatry · doi:10.1097/chi.0b013e3180686d7e · Cited by 323
Methylphenidate for attention deficit hyperactivity disorder (ADHD) in children and adolescents - assessment of adverse events in non-randomised studies
Storebø, O. J., Pedersen, N., Ramstad, E., Kielsholm, M. L., Nielsen, S. S., Krogh, H. B., Moreira-Maia, C. R., Magnusson, F. L., Holmskov, M., Gerner, T., et al. (2018) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd012069.pub2 · Cited by 321
Attention-Deficit/Hyperactivity Disorder (ADHD) and Obesity: A Systematic Review of the Literature
Cortese, S., Angriman, M., Maffeis, C., Isnard, P., Konofal, É., Lecendreux, M., Purper‐Ouakil, D., Vincenzi, B., Bernardina, B. D., & Mouren, M. (2008) · Critical Reviews in Food Science and Nutrition · doi:10.1080/10408390701540124 · Cited by 271
Long-Term, Open-Label Extension Study of Guanfacine Extended Release in Children and Adolescents with ADHD
Biederman, J., Melmed, R. D., Patel, A., McBurnett, K., Donahue, J., & Lyne, A. (2008) · CNS Spectrums · doi:10.1017/s1092852900017107 · Cited by 270
Self-citation
Potential adverse effects of amphetamine treatment on brain and behavior: a review
Berman, S. M., Kuczenski, R. T., McCracken, J. T., & London, E. D. (2008) · Molecular Psychiatry · doi:10.1038/mp.2008.90 · Cited by 263
Neuropsychopharmacology
Rendleman, R. L., & Walkup, J. T. (2012) · Elsevier eBooks · doi:10.1016/b978-1-4377-0435-8.00049-4 · Cited by 197
Attention-Deficit/Hyperactivity Disorder (ADHD) and Obesity: Update 2016
Cortese, S., & Tessari, L. (2017) · Current Psychiatry Reports · doi:10.1007/s11920-017-0754-1 · Cited by 192
Obesity and ADHD: Clinical and Neurobiological Implications
Cortese, S., & Vincenzi, B. (2011) · Current topics in behavioral neurosciences · doi:10.1007/7854_2011_154 · Cited by 171
Pharmacologic treatment of attention-deficit/hyperactivity disorder: efficacy, safety and mechanisms of action
Pliszka, S. R. (2007) · Neuropsychology Review · doi:10.1007/s11065-006-9017-3 · Cited by 158
Understanding the Risk of Using Medications for Attention Deficit Hyperactivity Disorder with Respect to Physical Growth and Cardiovascular Function
Vitiello, B. (2008) · Child and Adolescent Psychiatric Clinics of North America · doi:10.1016/j.chc.2007.11.010 · Cited by 113
Long term methylphenidate exposure and growth in children and adolescents with ADHD. A systematic review and meta-analysis
Carucci, S., Balia, C., Gagliano, A., Lampis, A., Buitelaar, J. K., Danckaerts, M., Dittmann, R., Garas, P., Hollis, C. P., Inglis, S. K., et al. (2020) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2020.09.031 · Cited by 119
Comorbidity between ADHD and Obesity: Exploring Shared Mechanisms and Clinical Implications
Cortese, S., & Morcillo, C. (2010) · Postgraduate Medicine · doi:10.3810/pgm.2010.09.2205 · Cited by 102
Attention Deficit Disorder, Stimulant Use, and Childhood Body Mass Index Trajectory
Schwartz, B. S., Bailey-Davis, L. D., Bandeen‐Roche, K., Pollak, J., Hirsch, A. G., Nau, C., Liu, A. Y., & Glass, T. A. (2014) · PEDIATRICS · doi:10.1542/peds.2013-3427 · Cited by 94
Common obesity risk alleles in childhood attention‐deficit/hyperactivity disorder
Albayrak, Ö., Pütter, C., Volckmar, A., Cichon, S., Hoffmann, P., Nöthen, M. M., Jöckel, K., Schreiber, S., Wichmann, H. ‐., Faraone, S. V., et al. (2013) · American Journal of Medical Genetics Part B Neuropsychiatric Genetics · doi:10.1002/ajmg.b.32144 · Cited by 94
Self-citation
ADHD, Stimulant Treatment, and Growth: A Longitudinal Study
Harstad, E. B., Weaver, A. L., Katusic, S. K., Colligan, R. C., Kumar, S., Chan, E., Voigt, R. G., & Barbaresi, W. J. (2014) · PEDIATRICS · doi:10.1542/peds.2014-0428 · Cited by 90
A clinical review of outcomes of the Multimodal Treatment Study of Children with Attention-Deficit/Hyperactivity Disorder (MTA)
Murray, D. W., Arnold, L. E., Swanson, J., Wells, K., Burns, K. E. A., Jensen, P. S., Hechtman, L. T., Paykina, N., Legato, L. J., & Strauss, T. (2008) · Current Psychiatry Reports · doi:10.1007/s11920-008-0068-4 · Cited by 80
Treating attention-deficit/hyperactivity disorder beyond symptom control alone in children and adolescents: a review of the potential benefits of long-acting stimulants
Buitelaar, J. K., & Medori, R. (2009) · European Child & Adolescent Psychiatry · doi:10.1007/s00787-009-0056-1 · Cited by 80
Effects of Atomoxetine on Growth in Children with Attention-Deficit/Hyperactivity Disorder Following up to Five Years of Treatment
Spencer, T. J., Kratochvil, C. J., Sangal, R. B., Saylor, K. E., Bailey, C. E., Dunn, D. W., Geller, D. A., Casat, C. D., Lipetz, R. S., Jain, R., et al. (2007) · Journal of Child and Adolescent Psychopharmacology · doi:10.1089/cap.2006.0100 · Cited by 75
Self-citation
Adverse Reactions to Methylphenidate Treatment for Attention-Deficit/Hyperactivity Disorder: Structure and Associations with Clinical Characteristics and Symptom Control
Sonuga-Barke, E. J. S., Coghill, D., Wigal, T., DeBacker, M., & Swanson, J. (2009) · Journal of Child and Adolescent Psychopharmacology · doi:10.1089/cap.2009.0024 · Cited by 71
Drug Holidays From ADHD Medication
Ibrahim, K., & Donyai, P. (2014) · Journal of Attention Disorders · doi:10.1177/1087054714548035 · Cited by 72
Psychopharmacological Interventions
Biederman, J., & Spencer, T. J. (2008) · Child and Adolescent Psychiatric Clinics of North America · doi:10.1016/j.chc.2007.12.001 · Cited by 62
Self-citation
Attention-Deficit Hyperactivity Disorder (ADHD): Does New Research Support Old Concepts?
Furman, L. (2008) · Journal of Child Neurology · doi:10.1177/0883073808318059 · Cited by 59
Long-Term Effects of Methylphenidate Transdermal Delivery System Treatment of ADHD on Growth
FARAONE, S. V., & GIEFER, E. E. (2007) · Journal of the American Academy of Child & Adolescent Psychiatry · doi:10.1097/chi.0b013e31806ad1d7 · Cited by 55
Self-citation
Medical Adaptation to Academic Pressure
King, M. D., Jennings, J. L., & Fletcher, J. M. (2014) · American Sociological Review · doi:10.1177/0003122414553657 · Cited by 55
A Randomized, Double-Blind, Placebo-Controlled Phase 2 Study of α4β2 Agonist ABT-894 in Adults with ADHD
Bain, E., Robieson, W., Pritchett, Y., Garimella, T., Abi-Saab, W., Apostol, G., McGough, J., & Saltarelli, M. (2013) · Neuropsychopharmacology · doi:10.1038/npp.2012.194 · Cited by 50
Long-Term Outcomes with Medications for Attention-Deficit Hyperactivity Disorder
Huang, Y., & Tsai, M.-H. (2011) · CNS Drugs · doi:10.2165/11589380-000000000-00000 · Cited by 54
Current issues around the pharmacotherapy of ADHD in children and adults
Meijer, W. M., Faber, A., van den Ban, E. F., & Tobi, H. (2009) · Pharmacy World & Science · doi:10.1007/s11096-009-9302-3 · Cited by 55
A compound herbal preparation (CHP) in the treatment of children with adhd: A randomized controlled trial
Katz, M., Adar Levine, A., Kol-Degani, H., & Kav-Venaki, L. (2010) · Journal of Attention Disorders · doi:10.1177/1087054709356388 · Cited by 48
Fitness Level and Gross Motor Performance of Children With Attention-Deficit Hyperactivity Disorder
Verret, C., Gardiner, P. F., & Béliveau, L. (2010) · Adapted Physical Activity Quarterly · doi:10.1123/apaq.27.4.337 · Cited by 48
Prevalence of Overweight and Obesity in Children and Adolescents With ADHD: The Significance of Comorbidities and Pharmacotherapy
Racicka, E., Hanć, T., Kuć, K., Bryńska, A., & Wolańczyk, T. (2015) · Journal of Attention Disorders · doi:10.1177/1087054715578272 · Cited by 42
Effects of Lisdexamfetamine Dimesylate Treatment for ADHD on Growth
Faraone, S. V., Spencer, T. J., Kollins, S. H., & Glatt, S. J. (2010) · Journal of the American Academy of Child & Adolescent Psychiatry · doi:10.1097/00004583-201001000-00006 · Cited by 39
Self-citation
Effect of Stimulants on Height and Weight: A Review of the Literature
Faraone, S. V., Biederman, J., Morley, C. P., & Spencer, T. J. (2008) · Journal of the American Academy of Child & Adolescent Psychiatry · doi:10.1097/chi.obo13e31817eoea7 · Cited by 286
Self-citation
A Long-Term Open-Label Safety and Effectiveness Trial of Lisdexamfetamine Dimesylate in Adolescents With Attention-Deficit/Hyperactivity Disorder
Findling, R. L., Cutler, A. J., Saylor, K., Gasior, M., Hamdani, M., Ferreira-Cornwell, M. C., & Childress, A. C. (2013) · Journal of Child and Adolescent Psychopharmacology · doi:10.1089/cap.2011.0088 · Cited by 40
ADHD and overweight in boys: cross-sectional study with birth weight as a controlled factor
Hanć, T., Słopień, A., Wolańczyk, T., Dmitrzak‐Węglarz, M., Szwed, A., Czapla, Z., Durda, M., Ratajczak, J., & Cieślik, J. J. (2014) · European Child & Adolescent Psychiatry · doi:10.1007/s00787-014-0531-1 · Cited by 38
The effects of long-term medication on growth in children and adolescents with ADHD: an observational study of a large cohort of real-life patients
Powell, S. G., Frydenberg, M., & Thomsen, P. H. (2015) · Child and Adolescent Psychiatry and Mental Health · doi:10.1186/s13034-015-0082-3 · Cited by 36
Effect of Stimulants on Height and Weight
Faraone, S. V., Biederman, J., Morley, C. P., & Spencer, T. J. (2008) · Journal of the American Academy of Child & Adolescent Psychiatry · doi:10.1097/chi.0b013e31817e0ea7 · Cited by 35
Self-citation
Effects of Osmotic-Release Methylphenidate on Height and Weight in Children With Attention-Deficit Hyperactivity Disorder (ADHD) Following up to Four Years of Treatment
Durá-Travé, T., Yoldi-Petri, M. E., Gallinas-Victoriano, F., & Zardoya-Santos, P. (2011) · Journal of Child Neurology · doi:10.1177/0883073811422752 · Cited by 34
The physical literacy of children with behavioural and emotional mental health disorders: A scoping review
Fortnum, K., Furzer, B. J., Reid, S. L., Jackson, B., & Elliott, C. M. (2018) · Mental health and physical activity · doi:10.1016/j.mhpa.2018.10.001 · Cited by 43
Trajectories of growth and symptoms of attention-deficit/hyperactivity disorder in children: a longitudinal study
Heinonen, K., Räikkönen, K., Pesonen, A., ANDERSSON, S. M., Kajantie, E., Eriksson, J. G., Vartia, T., Dieter Wolke, C., & Lano, A. (2011) · BMC Pediatrics · doi:10.1186/1471-2431-11-84 · Cited by 31
Clinical assessment and treatment of ADHD in children
Smoot, L. C., Boothby, L. A., & Gillett, R. C. (2007) · International Journal of Clinical Practice · doi:10.1111/j.1742-1241.2007.01519.x · Cited by 30
Long-Term Effects of Stimulant Treatment for ADHD: What Can We Tell Our Patients?
Craig, S. G., Davies, G., Schibuk, L., Weiss, M. D., & Hechtman, L. T. (2015) · Current Developmental Disorders Reports · doi:10.1007/s40474-015-0039-5 · Cited by 34
Methylphenidate in children with monogenic obesity due to LEPR or MC4R deficiency improves feeling of satiety and reduces BMI‐SDS—A case series
Brandt, S., von Schnurbein, J., Lennerz, B. S., Kohlsdorf, K., Vollbach, H., Denzer, C., Bode, H., Hebebrand, J., & Wabitsch, M. (2019) · Pediatric Obesity · doi:10.1111/ijpo.12577 · Cited by 26
Attention-Deficit/Hyperactivity Disorder, Iron Deficiency, and Obesity: Is There a Link?
Cortese, S., & Angriman, M. (2014) · Postgraduate Medicine · doi:10.3810/pgm.2014.07.2793 · Cited by 26
Effects of long-term methylphenidate use on growth and blood pressure: results of the German Health Interview and Examination Survey for Children and Adolescents (KiGGS)
McCarthy, S., Neubert, A., Man, K. K. C., Banaschewski, T., Buitelaar, J., Carucci, S., Coghill, D., Danckaerts, M., Falissard, B., Garas, P., et al. (2018) · BMC Psychiatry · doi:10.1186/s12888-018-1884-7 · Cited by 25
Inhaled Corticosteroids and Growth: Still an Issue after All These Years
Allen, D. B. (2014) · The Journal of Pediatrics · doi:10.1016/j.jpeds.2014.09.055 · Cited by 25
Long-Term Safety of Stimulant Medications Used to Treat Children with ADHD
Lerner, M., & Wigal, T. L. (2008) · Pediatric Annals · doi:10.3928/00904481-20080101-11 · Cited by 25
Self-citation
Effect of Methylphenidate on Height and Weight in Korean Children and Adolescents with Attention-Deficit/Hyperactivity Disorder: A Retrospective Chart Review
Kim, H., Kim, S., Shon, S., Lee, J., Lee, H., & Choi, J. (2014) · Journal of Child and Adolescent Psychopharmacology · doi:10.1089/cap.2014.0025 · Cited by 23
Dietary intake, growth and development of children with ADHD in a randomized clinical trial of Ritalin and Melatonin co-administration: Through circadian cycle modification or appetite enhancement?
Mostafavi, S., Mohammadi, M. R., Hosseinzadeh, P., Eshraghian, M. R., Akhondzadeh, S., Hosseinzadeh‐Attar, M. J., Ranjbar, E., Kooshesh, S.-M.-A., & Keshavarz, S. A. (2012) · PubMed Central · Cited by 22
Growth and Puberty in a 2-Year Open-Label Study of Lisdexamfetamine Dimesylate in Children and Adolescents with Attention-Deficit/Hyperactivity Disorder
Banaschewski, T., Johnson, M., Nagy, P., Otero, I. H., Soutullo, C. A., Yan, B. M., Zuddas, A., & Coghill, D. (2018) · CNS Drugs · doi:10.1007/s40263-018-0514-8 · Cited by 22
Rethinking the association between overweight/obesity and ADHD in children: a longitudinal and psychosocial perspective
Donnchadha, S. Ó., Bramham, J., & Greene, C. M. (2020) · Irish Journal of Psychological Medicine · doi:10.1017/ipm.2019.61 · Cited by 23
ADHD: What Do We Really Know?
Furman, L. (2009) · doi:10.1007/978-1-137-02058-1_2 · Cited by 21
Medication options when treating children and adolescents with ADHD: interpreting the NICE guidance 2006: Figure 1
Harpin, V. (2008) · Archives of Disease in Childhood Education & Practice · doi:10.1136/adc.2006.106864 · Cited by 21
Long-Term Safety of Stimulant Medications Used to Treat Children with ADHD
Lerner, M., & Wigal, T. L. (2008) · Journal of Psychosocial Nursing and Mental Health Services · doi:10.3928/02793695-20080801-06 · Cited by 20
Self-citation
The safety of extended-release drug formulations for the treatment of ADHD
Childress, A. C. (2017) · Expert Opinion on Drug Safety · doi:10.1080/14740338.2017.1317344 · Cited by 22
Changes and Challenges: Managing ADHD in a Fast-Paced World
Manos, M. J., Tom-Revzon, C., Bukstein, O. G., & Crismon, M. L. (2007) · Journal of Managed Care Pharmacy · doi:10.18553/jmcp.2007.13.9-b.1 · Cited by 18
Impact of CNS Stimulants for Attention-Deficit/Hyperactivity Disorder on Growth: Epidemiology and Approaches to Management in Children and Adolescents
Baweja, R. K., Hale, D. E., & Waxmonsky, J. G. (2021) · CNS Drugs · doi:10.1007/s40263-021-00841-w · Cited by 19
Review of the association between obesity and ADHD.
de Velasco, R. M., Barbudo, E., Pérez-Templado, J., Silveira, B., & Quintero, J. (2015) · Actas Españolas de Psiquiatría · Cited by 18
Stimulants and growth in children with attention-deficit/hyperactivity disorder
Negrao, B. L., & Viljoen, M. (2011) · Medical Hypotheses · doi:10.1016/j.mehy.2011.03.015 · Cited by 17
Evaluation of the current data on guanfacine extended release for the treatment of ADHD in children and adolescents
Childress, A. C., Hoo-Cardiel, A., & Lang, P. (2020) · Expert Opinion on Pharmacotherapy · doi:10.1080/14656566.2019.1706480 · Cited by 20
Central stimulants in the treatment of attention-deficit hyperactivity disorder (ADHD) in children and adolescents. A naturalistic study of the prescription in Sweden, 1977–2007
Janols, L., Liliemark, J. O., Klintberg, K., & von Knorring, A. (2009) · Nordic Journal of Psychiatry · doi:10.3109/08039480903154534 · Cited by 15
Seasonal Patterns of Medications for Treating Attention-Deficit/Hyperactivity Disorder: Comparison of Methylphenidate and Atomoxetine
Shyu, Y., Lee, S.-Y., Yuan, S.-S., Yang, C.-J., Yang, K., Lee, T., & Wang, L.-J. (2016) · Clinical Therapeutics · doi:10.1016/j.clinthera.2016.01.015 · Cited by 15
Prior Treatment with Stimulant Medication: A Much Neglected Confounder of Studies of Growth in Children with Attention-Deficit/Hyperactivity Disorder
Poulton, A. S., & Nanan, R. K. H. (2008) · Journal of Child and Adolescent Psychopharmacology · doi:10.1089/cap.2008.0011 · Cited by 14
Chronic methylphenidate treatment during adolescence has long-term effects on monoaminergic function
Miceli, M. D., Omoloye, A., & Gronier, B. (2018) · Journal of Psychopharmacology · doi:10.1177/0269881118805494 · Cited by 14
Methylphenidate Controlled-Delivery Capsules (Equasym???XL, Metadate CD???)
Anderson, V. R., & Keating, G. M. (2006) · Pediatric Drugs · doi:10.2165/00148581-200608050-00005 · Cited by 14
Methylphenidate and atomoxetine treatment negatively affect physical growth indexes of school-age children and adolescents with attention-deficit/hyperactivity disorder
Deng, L., Zhou, P., Zhu, L., Zhang, Y., Yang, T., Zhao, Q., Chen, J., Li, T., Cheng, Q., & Chen, L. (2021) · Pharmacology Biochemistry and Behavior · doi:10.1016/j.pbb.2021.173225 · Cited by 15
Management of Psychotropic Medication Side Effects in Children and Adolescents
García, G., Logan, G. E., & Gonzalez–Heydrich, J. (2012) · Child and Adolescent Psychiatric Clinics of North America · doi:10.1016/j.chc.2012.07.012 · Cited by 16
Preliminary Investigation of Association between Methylphenidate and Serum Growth Markers in Children with Attention-Deficit/Hyperactivity Disorder: A Cross-Sectional Case-Control Study
Kim, W. J., Bang, Y. R., Kang, J.-W., Yoo, J. H., Kim, S. H., & Park, J.-H. (2020) · Journal of korean Academy of Child and Adolescent Psychiatry · doi:10.5765/jkacap.200014 · Cited by 12
Growth perturbations from stimulant medications and inhaled corticosteroids
Richardson, E., Seibert, T. S., & Uli, N. K. (2017) · Translational Pediatrics · doi:10.21037/tp.2017.09.14 · Cited by 12
Pharmacologic treatment of ADHD: road conditions in driving patients to successful outcomes.
Manos, M. J. (2008) · PubMed Central · Cited by 11
The Impact of Religion on Family Functioning in Low-Income African American Families With Adolescents
Sisselman-Borgia, A., Budescu, M., & Taylor, R. D. (2018) · Journal of Black Psychology · doi:10.1177/0095798418771808 · Cited by 15
A criança hiperactiva: Diagnóstico, avaliação e intervenção
Cordinhã, A. C., & Boavida, J. (2008) · Revista Portuguesa de Clínica Geral · doi:10.32385/rpmgf.v24i5.10548 · Cited by 10
Impact of Medications Prescribed for Treatment of Attention-Deficit Hyperactivity Disorder on Physical Growth in Children and Adolescents With HIV
Sirois, P. A., Montepiedra, G., Kapetanovic, S., Williams, P. L., Pearson, D. A., Malee, K., Garvie, P. A., Kammerer, B. L., Nichols, S., Nozyce, M. L., et al. (2009) · Journal of Developmental & Behavioral Pediatrics · doi:10.1097/dbp.0b013e3181ba0cf6 · Cited by 10
The Effects of Methylphenidate Treatment on Child Growth in Thai Children and Adolescents with Attention-Deficit/Hyperactivity Disorder
Koonrungsesomboon, K., & Koonrungsesomboon, N. (2019) · Journal of Child and Adolescent Psychopharmacology · doi:10.1089/cap.2019.0115 · Cited by 12
Pharmacotherapy of ADHD in young children.
Vaughan, B. S., & Kratochvil, C. J. (2006) · PubMed Central · Cited by 9
Attention-Deficit/Hyperactivity Disorder Medication Treatment Impact on Response to Growth Hormone Therapy: Results from the ANSWER Program, a Non-Interventional Study
Rose, S. R., Reeves, G., Gut, R., & Germak, J. A. (2015) · The Journal of Pediatrics · doi:10.1016/j.jpeds.2015.08.036 · Cited by 9
A 24-Month Effects of Methylphenidate Use on Growth in Children and Adolescents With Attention Deficit Hyperactivity Disorder
Lee, Y., Kong, N., Koo, S., Bai, D.-S., Kim, H. J., Jeong, H., & Seo, W. S. (2022) · Psychiatry Investigation · doi:10.30773/pi.2021.0309 · Cited by 10
Safety and Tolerability of Serdexmethylphenidate/Dexmethylphenidate Capsules in Children with Attention-Deficit/Hyperactivity Disorder: A 12-Month, Open-Label Safety Study
Childress, A., Marraffino, A., Cutler, A., Oh, C., & Brams, M. (2023) · Journal of child and adolescent psychopharmacology · doi:10.1089/cap.2022.0076 · Cited by 7
A clinical review of outcomes of the Multimodal treatment study of children with attention-deficit/hyperactivity disorder (MTA)
Murray, D. W., Arnold, L. E., Swanson, J., Wells, K., Burns, K. E. A., Jensen, P. S., Hechtman, L. T., Paykina, N., Legato, L. J., & Strauss, T. (2009) · Current Attention Disorders Reports · doi:10.1007/s12618-009-0007-2 · Cited by 8
Effect of methylphenidate on height in pediatric attention-deficit hyperactivity disorder patients: a systematic review and meta-analysis
Duong, K. L., Yang, B. R., Yun, H., & Chae, J. (2023) · European Child & Adolescent Psychiatry · doi:10.1007/s00787-023-02273-x · Cited by 7
El tratamiento del niño y adolescente con TDAH en Atención Primaria desde el punto de vista de la evidencia
Espinosa, A. L. (2006) · Hispana · Cited by 7
Mediators of psychosocial treatment for adolescent ADHD.
Sibley, M. H., Coxe, S. J., Zulauf-McCurdy, C. A., & Zhao, X. (2022) · Journal of Consulting and Clinical Psychology · doi:10.1037/ccp0000743 · Cited by 6
Psychostimulants and Other Drugs Used in the Treatment of Attention-Deficit/Hyperactivity Disorder (ADHD)
Walitza, S., Romanos, M., Warnke, A., Greenhill, L. L., & Gerlach, M. (2014) · Springer eBooks · doi:10.1007/978-3-7091-1501-5_8 · Cited by 6
Stress levels experienced by parents of children with and without attention-deficit/hyperactivity disorder during the back-to-school period: results of a European and Canadian survey
Otero, I. H., Doddamani, L., Dutray, B., Gagliano, A., Haertling, F., Bloomfield, R., & Ramnath, G. (2014) · International Journal of Psychiatry in Clinical Practice · doi:10.3109/13651501.2014.961928 · Cited by 6
Long-term Safety of Stimulant Medications Used to Treat Children with ADHD
Lerner, M., & Wigal, T. L. (2008) · Psychiatric Annals · doi:10.3928/00485713-20080101-10 · Cited by 6
Self-citation
A Randomized Community-Based Trial of Behavior Therapy vs. Usual Care for Adolescent ADHD: Secondary Outcomes and Effects on Comorbidity
Sibley, M. H., Graziano, P. A., Coxe, S. J., Bickman, L., Martin, P., & Flores, S. (2023) · Behavior Therapy · doi:10.1016/j.beth.2023.03.001 · Cited by 8
Analysis of Growth Velocity in Children with Attention-Deficit/Hyperactivity Disorder Treated for up to 12 Months with Serdexmethylphenidate/Dexmethylphenidate
Childress, A. C., Cutler, A. J., Patel, M., & Oh, C. (2023) · Journal of Child and Adolescent Psychopharmacology · doi:10.1089/cap.2023.0012 · Cited by 5
Effects of methylphenidate on height, weight and blood biochemistry parameters in prepubertal boys with attention deficit hyperactivity disorder: an open label prospective study
Çevikaslan, A., Parlak, M., Elli̇dağ, H. Y., Kulaksızoğlu, S., & Yılmaz, N. (2021) · Scandinavian Journal of Child and Adolescent Psychiatry and Psychology · doi:10.21307/sjcapp-2021-018 · Cited by 5
The Comorbid Diagnosis of ASD and ADHD: Clinical and Neuropsychological Perspectives
May, T., Sciberras, E., Hiscock, H., & Rinehart, N. (2016) · Autism and child psychopathology series · doi:10.1007/978-3-319-27171-2_14 · Cited by 5
Hiperatividade e déficit de atenção: o tratamento prejudica o crescimento estatural?
Damiani, D., Damiani, D., & Casella, E. B. (2010) · Arquivos Brasileiros de Endocrinologia & Metabologia · doi:10.1590/s0004-27302010000300003 · Cited by 6
A Pathophysiologic Approach to Growth Problems in Children with Attention-Deficit/Hyperactivity Disorder
Tenore, A., & Tenore, A. (2012) · Endocrinology and Metabolism Clinics of North America · doi:10.1016/j.ecl.2012.08.004 · Cited by 5
Nutrición y trastorno por déficit de atención/hiperactividad: seguimiento evolutivo de las variables antropométricas de un grupo de pacientes en tratamiento con metilfenidato de liberación osmótica
Durá-Travé, T., Yoldi-Petri, M. E., & Zardoya-Santos, P. (2011) · Revista de Neurología · doi:10.33588/rn.5305.2011284 · Cited by 4
The Effect of Methylphenidate on Cervical Vertebral Maturation and Dental Age in Patients with Attention Deficit Hyperactivity Disorder.
Tehranchi, A., Younessian, F., Fadaei, V., Arabgol, F., & Shirvani, A. (2018) · PubMed Central · Cited by 4
EFFECT OF LONG-TERM TREATMENT WITH STIMULANT MEDICATION ON GROWTH?
Poulton, A. S. (2007) · Journal of the American Academy of Child & Adolescent Psychiatry · doi:10.1097/chi.0b013e31802ed90e · Cited by 4
Effects of Long Acting Methylphenidate on Ghrelin Levels in Male Children with Attention Deficit Hyperactivity Disorder: An Open Label Trial
Yalçın, Ö., İşeri, E., Bukan, N. C., & Erçin, U. (2014) · Klinik Psikofarmakoloji Bülteni-Bulletin of Clinical Psychopharmacology · doi:10.5455/bcp.20130708042604 · Cited by 5
Uso clínico de metilfenidato 30:70 de liberación modificada en el tratamiento del trastorno por déficit de atención/hiperactividad
Mardomingo, M. J. (2012) · Revista de Neurología · doi:10.33588/rn.5506.2011528 · Cited by 3
EFFECT OF LONG-TERM TREATMENT WITH STIMULANT MEDICATION ON GROWTH?
Spencer, T. J., Faraone, S. V., Lerner, M., Cooper, K., & Zimmerman, B. A. (2007) · Journal of the American Academy of Child & Adolescent Psychiatry · doi:10.1097/chi.0b013e31802ed960 · Cited by 2
Self-citation
Effect of methylphenidate on physical growth indicators in children and adolescents with attention-deficit/hyperactivity disorder: a systematic review and meta-analysis
Cao, M., Song, T., Hou, X., & Yu, X. (2026) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2026.1794403 · Cited by 1
Dikkat Eksikliği Hiperaktivite Bozukluğu ve Obezite Birlikteliği: Bir Sistematik Gözden Geçirme
Temtek, S., Göker, Z., & Üneri, Ö. Ş. (2019) · Psikiyatride Guncel Yaklasimlar - Current Approaches in Psychiatry · doi:10.18863/pgy.457600 · Cited by 1
Central nervous system stimulants and drugs that suppress appetite
Sequeira, R. P. (2009) · Side effects of drugs annual · doi:10.1016/s0378-6080(09)03101-8 · Cited by 1

Authors: SPENCER, T. J., FARAONE, S. V., BIEDERMAN, J., LERNER, M., COOPER, K. M., & ZIMMERMAN, B.
Affiliations: SUNY Upstate Medical University (US)
Corresponding author: SPENCER, THOMAS J.
ORCID: SPENCER, THOMAS J.
FARAONE, STEPHEN V.
BIEDERMAN, JOSEPH
Venue: Journal of the American Academy of Child & Adolescent Psychiatry
Publisher: Elsevier BV
Published: 2006-05
Volume: 45
Issue: 5
Pages: 527-537
ISSN: 0890-8567 (ISSN-L)
DOI: 10.1097/01.chi.0000205710.01690.d4
OpenAlex: W2077454035
Cited by: 125
References: 41
Citations by year: 2026: 1 · 2025: 1 · 2024: 1 · 2023: 4 · 2022: 3 · 2021: 4 · 2020: 4 · 2019: 5 · 2018: 7 · 2017: 3 · 2016: 2 · 2015: 9 · 2014: 12 · 2013: 2 · 2012: 6
FWCI: 9.54
Type: journal article
Language: en
Open access: closed
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Locations: Journal of the American Academy of Child & Adolescent Psychiatry (publishedVersion)
PubMed (publishedVersion)
Topics: Health Sciences › Medicine › Psychiatry and Mental health › Attention Deficit Hyperactivity Disorder
Health Sciences › Medicine › Pediatrics, Perinatology and Child Health › Pharmaceutical studies and practices
Health Sciences › Medicine › Pharmacology (medical) › Pharmacology and Obesity Treatment
Keywords: attention deficit hyperactivity disorder, long-acting stimulants, OROS methylphenidate, growth inhibition, height, weight, body mass index, drug holidays, children
MeSH terms: Central Nervous System Stimulants, Attention Deficit Disorder with Hyperactivity, Body Height, Body Weight, Child, Clinical Trials as Topic, Delayed-Action Preparations, Dose-Response Relationship, Drug, Female, Follow-Up Studies, Humans, Long-Term Care, Male, Methylphenidate, Body Mass Index

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Does Prolonged Therapy With a Long-Acting Stimulant Suppress Growth in Children With ADHD?

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Citations

Cites

Cited by

Related

Metadata

Record

About these checks