Cited by 510Attention Deficit Hyperactivity DisorderChild and Adolescent Psychosocial and Emotional DevelopmentDevelopmental and Educational Neuropsychology

Predictors of Persistence and Remission of ADHD into Adolescence: Results from a Four-Year Prospective Follow-up Study

BIEDERMAN, JOSEPH, FARAONE, STEPHEN, MILBERGER, SHARON, CURTIS, SHANNON, CHEN, LISA, MARRS, ABBE, OUELLETTE, CHERYL, MOORE, PHOEBE +1 more·1996·Journal of the American Academy of Child & Adolescent Psychiatry

Abstract

Objective To evaluate the predictors of persistence and the timing of remission of attention-deficit hyperactivity disorder (ADHD). Method Subjects were 6- to 17-year old Caucasian, non-Hispanic boys with and without ADHD. DSM-III-R structured diagnostic interviews and blind raters were used to examine psychiatric diagnoses, cognitive achievement, social, school, and family functioning at a 4-year follow-up assessment. Results At the 4-year follow-up assessment, 85% of children with ADHD continued to have the disorder and 15% remitted. Of those who remitted, half did so in childhood and the other half in adolescence. Predictors of persistence were familiality of ADHD, psychosocial adversity, and comorbidity with conduct, mood, and anxiety disorders. Conclusions The findings prospectively confirm that the majority of children with ADHD will continue to express the disorder 4 years later. For a minority of children, ADHD was a transient disorder that remits early in development. In addition, we have shown that persistence of ADHD is predictable. Familiality, adversity, and psychiatric comorbidity may be clinically useful predictors of which children with ADHD are at risk for a persistent disorder.

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Crossref · 10.1097/00004583-199603000-00016

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7 of 7 references verified0 citation errors · 0 not checkable

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  • Most ADHD longitudinal studies simply define remission as failing to meet DSM criteria, with few attempts to identify or define distinct subtypes and patterns of remission.

    “Most ADHD longitudinal studies simply define remission as “failing to meet DSM criteria,” with few attempts to identify/define distinct subtypes and patterns of remission.”
  • Most longitudinal work on ADHD remission and persistence reports only a single-time snapshot of functioning.

    “Most longitudinal work on ADHD remission and persistence reports only a single-time snapshot of functioning, even though ADHD is considered a life-course disorder.”
  • ADHD is considered a life-course disorder.

    “even though ADHD is considered a life-course disorder.”
  • There is virtually no scientific information on the extent to which individuals sustain remission long-term, experience recurrence of ADHD post-remission, or fluctuate between full remission, partial remission, and ADHD persistence.

    “There is virtually no scientific information on the extent to which individuals sustain remission long-term (i.e., recover from ADHD symptoms and impairments), experience recurrence of ADHD post-remission (i.e., remission is temporary), or fluctuate between full remission, partial remission, and ADHD persistence (whether ADHD might be a waxing and waning disorder).”

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Authors
BIEDERMAN, J., FARAONE, S., MILBERGER, S., CURTIS, S., CHEN, L., MARRS, A., OUELLETTE, C., MOORE, P., & SPENCER, T.
Affiliations
Massachusetts General Hospital (US)
Corresponding author
BIEDERMAN, JOSEPH
Venue
Journal of the American Academy of Child & Adolescent Psychiatry
Publisher
Elsevier BV
Published
1996-03
Volume
35
Issue
3
Pages
343-351
ISSN
0890-8567 (ISSN-L)
OpenAlex
W2093507141
Cited by
510
References
7
Citations by year
2025: 8 · 2024: 4 · 2023: 7 · 2022: 7 · 2021: 13 · 2020: 12 · 2019: 8 · 2018: 11 · 2017: 15 · 2016: 24 · 2015: 23 · 2014: 22 · 2013: 34 · 2012: 31
FWCI
11.60
Type
journal article
Language
en
Open access
closed
Locations
  • Journal of the American Academy of Child & Adolescent Psychiatry (publishedVersion)
  • PubMed (publishedVersion)
Funders
NIMH (MH41314–08)
Topics
  • Health Sciences › Medicine › Psychiatry and Mental health › Attention Deficit Hyperactivity Disorder
  • Social Sciences › Psychology › Clinical Psychology › Child and Adolescent Psychosocial and Emotional Development
  • Social Sciences › Psychology › Neuropsychology and Physiological Psychology › Developmental and Educational Neuropsychology
Keywords
attention deficit hyperactivity disorder, ADHD persistence, predictors of remission, familiality, psychosocial adversity, psychiatric comorbidity, conduct disorder, mood disorders, anxiety disorders, children and adolescents, longitudinal follow-up
MeSH terms
Achievement, Adolescent, Psychology, Adolescent, Attention Deficit Disorder with Hyperactivity, Child, Cognition, Follow-Up Studies, Humans, Longitudinal Studies, Male, Prospective Studies, Psychiatric Status Rating Scales, Remission Induction

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