Cited by 208Probiotics and Fermented FoodsInfant Nutrition and HealthGut microbiota and health

A Randomized Formula Controlled Trial of Bifidobacterium lactis and Streptococcus thermophilus for Prevention of Antibiotic-Associated Diarrhea in Infants

Corrêa, Naflesia B. O, Péret Filho, Luciano A, Penna, Francisco J, Lima, Fátima M. L. S, Nicoli, Jacques R·2005·Journal of Clinical Gastroenterology

Abstract

GOALS: This clinical trial was carried out to determine whether oral treatment with a commercial probiotic formula containing Bifidobacterium lactis and Streptococcus thermophilus would reduce the frequency of antibiotic-associated diarrhea (AAD) in infants. STUDY: In this double-bind formula controlled study, 80 infants, 6 to 36 months of age, were randomly assigned to receive a commercial formula containing 10 viable cells of B. lactis and 10 viable cells of S. thermophilus at the initiation of antibiotics for a duration of 15 days. The infants were assessed daily for formula intake, stool frequency, and stool consistency for a total duration of 30 days. Seventy-seven infants received nonsupplemented formula for the entire duration. RESULTS: There was a significant difference in the incidence of AAD in the children receiving probiotic-supplemented formula (16%) than nonsupplemented formula (31%). CONCLUSIONS: The present study shows that prevention against AAD in infants was obtained by oral treatment with daily dose of B. lactis and S. thermophilus.

Integrity signals

Registry

Crossref · 10.1097/01.mcg.0000159217.47419.5b

Cites

31 of 31 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

  • Different bifidobacteria species, mostly combined with St. thermophilus and/or Lb. acidophilus, have been shown to be effective in the prevention and treatment of antibiotic associated diarrhea.

    “Different bifidobacteria species (B.animalis subsp.lactis, B. bifidum, or B. infantis), mostly combined with St. thermophilus and/or Lb. acidophilus, have been shown to be effective in the prevention and treatment of antibiotic associated diarrhea [129,130]”

Cites

Flagged first, then by citations

Cited by

Sorted by citations

Authors
Corrêa, N. B. O., Péret Filho, L. A., Penna, F. J., Lima, F. M. L. S., & Nicoli, J. R.
Affiliations
  • Universidade Federal de Minas Gerais (BR)
  • Universidade Federal de Goiás (BR)
Corresponding author
  • Corrêa, Naflesia B. O
  • Penna, Francisco J
Venue
Journal of Clinical Gastroenterology
Published
2005-05
Volume
39
Issue
5
Pages
385-389
ISSN
0192-0790 (ISSN-L)
OpenAlex
W2030409548
Cited by
208
References
31
Citations by year
2026: 5 · 2025: 10 · 2024: 5 · 2023: 8 · 2022: 6 · 2021: 12 · 2020: 9 · 2019: 15 · 2018: 6 · 2017: 9 · 2016: 6 · 2015: 11 · 2014: 8 · 2013: 14 · 2012: 16
FWCI
20.61
Type
journal article
Language
en
Open access
closed
Locations
  • Journal of Clinical Gastroenterology (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Life Sciences › Agricultural and Biological Sciences › Food Science › Probiotics and Fermented Foods
  • Health Sciences › Nursing › Nutrition and Dietetics › Infant Nutrition and Health
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Gut microbiota and health
Keywords
antibiotic-associated diarrhea, probiotics, Bifidobacterium animalis subsp. lactis, Streptococcus thermophilus, infants, diarrhea prevention, antibiotic therapy
MeSH terms
Administration, Oral, Anti-Bacterial Agents, Bifidobacterium, Diarrhea, Double-Blind Method, Female, Follow-Up Studies, Humans, Infant, Infections, Male, Treatment Outcome, Probiotics, Streptococcus thermophilus

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review