Effectiveness of a 3-week Multimodal Inpatient Pain Treatment for Adolescents Suffering From Chronic Pain: Statistical and Clinical Significance
Abstract
OBJECTIVE: The present study aimed to investigate the effectiveness of a 3-week multimodal inpatient pain program for children and adolescents with chronic pain. METHODS: Effectiveness was investigated for pain-related variables (pain intensity, pain-related disability) and emotional distress in 3 ways: (1) in terms of statistically significant changes; (2) in terms of the clinical significance of these changes by creating post-hoc outcome groups for pain-related variables and emotional distress; and (3) in terms of the clinically significant overall amelioration generalizing the outcome over 3 variables (ie, pain intensity, pain-related disability, and school absence). One hundred sixty-seven adolescents (aged between 11 and 18 y) with various pain disorders (50% with headache) who met inpatient criteria were evaluated at baseline and 3 months posttreatment. RESULTS: Patients demonstrated statistically significant changes in all variables with large to medium effect sizes. Seventy-two percent and 45% of the patients demonstrated clinically significant changes in pain intensity and pain-related disability, respectively. The percentages of patients demonstrating clinically significant change in emotional distress ranged from 13% to 26%. Seventy-seven adolescents demonstrated overall amelioration. DISCUSSION: Results of the study are promising in at least 2 ways: (1) a multimodal inpatient program might stop the negative effects of chronic pain, disability, and emotional distress in children and adolescents, and (2) the exploration of clinical significance testing has demonstrated utility and can be applied to future effectiveness studies in pediatric pain.
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Most current psychological and physiotherapeutic treatments for adolescents with chronic pain involve promoting pain coping strategies via psychological interventions, with separate physical therapy prescribed.
“Most current psychological and physiotherapeutic treatments for adolescents with chronic pain involve promoting pain coping strategies via psychological interventions, with separate physical therapy prescribed [9].”
Cites
Statistical Power Analysis for the Behavioral Sciences
Muller, K. E., & Cohen, J. (1989) · Technometrics · doi:10.2307/1270020 · Cited by 99,588 · see citing works
Jacobson, N. S., & Truax, P. (1991) · Journal of Consulting and Clinical Psychology · doi:10.1037/0022-006x.59.1.12 · Cited by 7,770 · see citing works
Farrar, J. T., Young, J. P., LaMoreaux, L., Werth, J. L., & Poole, M. R. (2001) · Pain · doi:10.1016/s0304-3959(01)00349-9 · Cited by 5,808 · see citing works
Benjamin, S. (1994) · Journal of Psychosomatic Research · doi:10.1016/0022-3999(94)90012-4 · Cited by 2,006 · see citing works
Pain in children and adolescents: a common experience
Perquin, C. W., Hazebroek-Kampschreur, A. A. J. M., Hunfeld, J. A. M., Bohnen, A. M., van Suijlekom-Smit, L. W. A., Passchier, J., & van der Wouden, J. C. (2000) · Pain · doi:10.1016/s0304-3959(00)00269-4 · Cited by 1,114 · see citing works
Psychotherapie im Wandel: von der Konfession zur Profession
Grawe, K., Donati, R., & Bernauer, F. (2001) · Cited by 772 · see citing works
von Baeyer, C. L., & Spagrud, L. J. (2006) · Pain · doi:10.1016/j.pain.2006.08.014 · Cited by 695 · see citing works
Perepletchikova, F., Treat, T. A., & Kazdin, A. E. (2007) · Journal of Consulting and Clinical Psychology · doi:10.1037/0022-006x.75.6.829 · Cited by 533 · see citing works
PALERMO, T. M. (2000) · Journal of Developmental & Behavioral Pediatrics · doi:10.1097/00004703-200002000-00011 · Cited by 494 · see citing works
Normative comparisons for the evaluation of clinical significance.
Kendall, P. C., Marrs, A. L., Nath, S. R., & Sheldrick, R. C. (1999) · Journal of Consulting and Clinical Psychology · doi:10.1037//0022-006x.67.3.285 · Cited by 468 · see citing works
Eccleston, C., Crombez, G., Scotford, A., Clinch, J., & Connell, H. (2004) · Pain · doi:10.1016/j.pain.2003.11.008 · Cited by 418 · see citing works
Wise, E. A. (2004) · Journal of Personality Assessment · doi:10.1207/s15327752jpa8201_10 · Cited by 399 · see citing works
Parent and family factors in pediatric chronic pain and disability: An integrative approach
Palermo, T. M., & Chambers, C. T. (2005) · Pain · doi:10.1016/j.pain.2005.10.027 · Cited by 384 · see citing works
Normative comparisons for the evaluation of clinical significance.
Kendall, P. C., Marrs-Garcia, A., Nath, S. R., et al. (1999) · Journal of Consulting and Clinical Psychology · doi:10.1037/0022-006x.67.3.285 · Cited by 350 · see citing works
Sherry, D. D., Wallace, C. A., Kelley, C. A., Kidder, M., & Sapp, L. R. (1999) · Clinical Journal of Pain · doi:10.1097/00002508-199909000-00009 · Cited by 345 · see citing works
Hotopf, M. H., Carr, S., Mayou, R., Wadsworth, M. E. J., & Wessely, S. C. (1998) · BMJ · doi:10.1136/bmj.316.7139.1196 · Cited by 307 · see citing works
Eccleston, C., Morley, S., Williams, A. C. D. C., Yorke, L., & Mastroyannopoulou, K. (2002) · Pain · doi:10.1016/s0304-3959(02)00072-6 · Cited by 295 · see citing works
McCracken, L. M., Gauntlett-Gilbert, J., & Vowles, K. E. (2007) · Pain · doi:10.1016/j.pain.2006.12.013 · Cited by 290 · see citing works
Eccleston, C. (2003) · Archives of Disease in Childhood · doi:10.1136/adc.88.10.881 · Cited by 276 · see citing works
Clinical Significance Methods: A Comparison of Statistical Techniques
Bauer, S., Lambert, M. J., & Nielsen, S. L. (2004) · Journal of Personality Assessment · doi:10.1207/s15327752jpa8201_11 · Cited by 258 · see citing works
Neglected topics in chronic pain treatment outcome studies: determination of success
Turk, D., Rudy, T., & Sorkin, B. A. (1993) · Pain · doi:10.1016/0304-3959(93)90049-u · Cited by 245 · see citing works
Sleed, M., Eccleston, C., Beecham, J., Knapp, M., & Jordan, A. (2005) · Pain · doi:10.1016/j.pain.2005.09.028 · Cited by 244 · see citing works
Haldorsen, E. M. H., Grasdal, A. L., Skouen, J. S., Risa, A. E., Kronholm, K., & Ursin, H. (2002) · Pain · doi:10.1016/s0304-3959(01)00374-8 · Cited by 240 · see citing works
Headache in German Children and Adolescents: A Population-Based Epidemiological Study
Kröner‐Herwig, B., Heinrich, M., & Morris, L. (2007) · Cephalalgia · doi:10.1111/j.1468-2982.2007.01319.x · Cited by 223 · see citing works
Reports of pain among German children and adolescents: an epidemiological study
Roth-Isigkeit, A., Thyen, U., Raspe, H. H., Stöven, H., & Schmucker, P. (2004) · Acta Paediatrica · doi:10.1111/j.1651-2227.2004.tb00717.x · Cited by 218 · see citing works
Assessing Clinical Significance: Proposed Extensions to Method
Tingey, R., Lambert, M. J., Burlingame, G. M., & Hansen, N. B. (1996) · Psychotherapy Research · doi:10.1080/10503309612331331638 · Cited by 198 · see citing works
Interdisciplinary treatment for fibromyalgia syndrome: clinical and statistical significance.
Turk, D. C., Okifuji, A., Sinclair, J., & Starz, T. (1998) · Arthritis care and research : the official journal of the Arthritis Health Professions Association · doi:10.1002/art.1790110306 · Cited by 196 · see citing works
Psychological Treatment of Recurrent Headache in Children and Adolescents - A Meta-Analysis
Trautmann, E., Lackschewitz, H., & Kröner‐Herwig, B. (2006) · Cephalalgia · doi:10.1111/j.1468-2982.2006.01226.x · Cited by 187 · see citing works
Imagination als heilsame Kraft
Reddemann, L. (2003) · Technische Universität Dortmund Eldorado (Technische Universität Dortmund) · doi:10.17877/de290r-2424 · Cited by 170 · see citing works
Matthey, S. (2004) · Journal of Affective Disorders · doi:10.1016/s0165-0327(02)00313-0 · Cited by 168 · see citing works
McCracken, L. M., MacKichan, F., & Eccleston, C. (2007) · European Journal of Pain · doi:10.1016/j.ejpain.2006.05.004 · Cited by 167 · cited 1× · see citing works
“0 15%-50% school absence 57 (34) 25 (18)”
Investigation and Treatment of Missing Item Scores in Test and Questionnaire Data
Sijtsma, K., & van der Ark, L. A. (2003) · Multivariate Behavioral Research · doi:10.1207/s15327906mbr3804_4 · Cited by 154 · see citing works
Headache Prevalence Among Adolescents — The German DMKG Headache Study
Fendrich, K., Vennemann, M., Pfaffenrath, V., Evers, S., May, A., Berger, K., & Hoffmann, W. U. (2007) · Cephalalgia · doi:10.1111/j.1468-2982.2007.01289.x · Cited by 153 · see citing works
Managing chronic pain in children and adolescents
Eccleston, C., & Malleson, P. N. (2003) · BMJ · doi:10.1136/bmj.326.7404.1408 · Cited by 148 · see citing works
Perquin, C. W., Hunfeld, J. A. M., Hazebroek-Kampschreur, A. A. J. M., van Suijlekom‐Smit, L. W. A., Passchier, J., Koes, B. W., & van der Wouden, J. C. (2003) · European Journal of Pain · doi:10.1016/s1090-3801(03)00060-0 · Cited by 119 · see citing works
Clinical Assessment and Management of Chronic Pain and Pain-Associated Disability Syndrome
Bursch, B., Walco, G. A., & Zeltzer, L. K. (1998) · Journal of Developmental & Behavioral Pediatrics · doi:10.1097/00004703-199802000-00008 · Cited by 114 · see citing works
Härkäpää, K., Järvikoski, A., Mellin, G. P., & Hurri, H. (1989) · Journal of Rehabilitation Medicine · doi:10.2340/1650197719898189 · Cited by 111 · see citing works
Rose, J., Loftus, M., Flint, B., & Carey, L. (2005) · British Journal of Clinical Psychology · doi:10.1348/014466505x29972 · Cited by 107 · see citing works
Jacobson, N. S., & Gortner, E. T. (2000) · Behaviour Research and Therapy · doi:10.1016/s0005-7967(99)00029-7 · Cited by 100 · see citing works
Newnham, E. A., Harwood, K. E., & Page, A. C. (2006) · Journal of Affective Disorders · doi:10.1016/j.jad.2006.07.001 · Cited by 97 · see citing works
Härkäpää, K., Mellin, G. P., Järvikoski, A., & Hurri, H. (2020) · Journal of Rehabilitation Medicine · doi:10.2340/165019779022181188 · Cited by 93 · see citing works
Statistical Significance Versus Clinical Importance
van Tulder, M. W., Malmivaara, A. O. V., Hayden, J. A., & Koes, B. W. (2007) · Spine · doi:10.1097/brs.0b013e3180b9ef49 · Cited by 83 · see citing works
Children with chronic pain: Impact of sex and age on long-term outcomes
Martin, A. L., McGrath, P. A., Brown, S. C., & Katz, J. (2007) · Pain · doi:10.1016/j.pain.2006.08.027 · Cited by 82 · see citing works
A controlled study of alexithymia in adolescent patients with persistent somatoform pain disorder
Burba, B., Oswald, R., Grigaliunien, V., Neverauskiene, S., Jankuviene, O., & Chue, P. (2006) · The Canadian Journal of Psychiatry · doi:10.1177/070674370605100709 · Cited by 78 · see citing works
Gil, K. M., Wilson, J. J., & Edens, J. L. (1997) · Clinical Journal of Pain · doi:10.1097/00002508-199706000-00005 · Cited by 64 · see citing works
Dobe, M., Damschen, U., Reiffer-Wiesel, B., Sauer, C., & Zernikow, B. (2006) · Der Schmerz · doi:10.1007/s00482-005-0457-0 · Cited by 63 · see citing works
Lutz, W., Martinovich, Z., Howard, K. I., & Leon, S. C. (2002) · Journal of Clinical Psychology · doi:10.1002/jclp.10070 · Cited by 47 · see citing works
Tsao, J. C. I., Lü, Q., Kim, S. C., & Zeltzer, L. K. (2006) · Cognitive Behaviour Therapy · doi:10.1080/16506070600898272 · Cited by 47 · see citing works
Openshaw, C., Waller, G., & Sperlinger, D. J. (2004) · International Journal of Eating Disorders · doi:10.1002/eat.20042 · Cited by 41 · see citing works
Treatment of children with unexplained chronic pain
Kashikar‐Zuck, S. (2006) · The Lancet · doi:10.1016/s0140-6736(06)68118-x · Cited by 40 · see citing works
Treatment of Functional Impairment in Severe Somatoform Pain Disorder: A Case Example
Palermo, T. M. (2001) · Journal of Pediatric Psychology · doi:10.1093/jpepsy/26.7.429 · Cited by 35 · see citing works
Schauenburg, H., & Strack, M. (1998) · PubMed · Cited by 33 · see citing works
Hsu, L. (1996) · Journal of Psychopathology and Behavioral Assessment · doi:10.1007/bf02229141 · Cited by 32 · see citing works
Chronic pain in children and adolescents
Eccleston, C., Bruce, E., & Carter, B. (2006) · Nursing Children and Young People · doi:10.7748/paed.18.10.30.s21 · Cited by 30 · see citing works
"Statistical significance and clinical significance are not synonyms!".
Turk, D. (2000) · The Clinical Journal of Pain · doi:10.1097/00002508-200009000-00001 · Cited by 30 · see citing works
Åsenlöf, P., Denison, E., & Lindberg, P. (2006) · Behaviour Research and Therapy · doi:10.1016/j.brat.2005.07.005 · Cited by 26 · see citing works
[Assessment and measurement of pain].
Denecke, H., & Hünseler, C. (2000) · PubMed · doi:10.1007/s004820000022 · Cited by 25 · see citing works
Personality disorders in a Dutch forensic psychiatric sample: changes with treatment
Greeven, P. G. J., & de Ruiter, C. (2004) · Criminal Behaviour and Mental Health · doi:10.1002/cbm.594 · Cited by 24 · see citing works
Risikofaktoren für Rückenschmerzen bei Kindern und Jugendlichen in Industrienationen
Roth-Isigkeit, A., Schwarzenberger, J. C., Baumeier, W., Meier, T., Lindig, M., & Schmucker, P. (2004) · Der Schmerz · doi:10.1007/s00482-004-0379-2 · Cited by 23 · see citing works
Messen und Erfassen von Schmerz
Hechler, T., Denecke, H., Hünseler, C., Schroeder, S., & Zernikow, B. (2009) · Springer eBooks · doi:10.1007/978-3-540-74065-0_5 · Cited by 23 · see citing works
Introduction to the Special Issue on Pain: From Pain to Pain-Associated Disability Syndrome
Zeltzer, L. K., Tsao, J. C. I., Bursch, B., & Myers, C. D. (2005) · Journal of Pediatric Psychology · doi:10.1093/jpepsy/jsj053 · Cited by 22 · see citing works
Messen und Erfassen von Schmerz
Denecke, H., & Hünseler, C. (2000) · Der Schmerz · doi:10.1007/s004820070016 · Cited by 22 · see citing works
Statistical significance versus clinical importance.
Prasad, K. (1994) · Stroke · doi:10.1161/str.25.7.1527b · Cited by 19 · see citing works
Rosqvist, J., Thomas, J. C., & Egan, D. (2002) · Behavior Modification · doi:10.1177/0145445502026002005 · Cited by 16 · see citing works
The Effectiveness of Hospitalization in the Treatment of Paediatric Idiopathic Headache Patients
Lanzi, G., D’Arrigo, S., Termine, C., Rossi, M., Ginevra, O. F., Mongelli, A., Millul, A., & Beghi, E. (2006) · Psychopathology · doi:10.1159/000096383 · Cited by 15 · see citing works
Pediatric Headache: An Examination of Process Variables in Treatment
Cvengros, J. A., Harper, D. C., & Shevell, M. I. (2007) · Journal of Child Neurology · doi:10.1177/0883073807305786 · Cited by 12 · see citing works
Bringing pain relief to children: a guide to practical management
Newman, C. J. (2007) · PubMed Central · doi:10.1136/adc.2006.103168 · Cited by 4 · see citing works
What's in a Face: Can parents “read pain” in their children's faces?
Zeltzer, L. K., & Tsao, J. C. I. (2006) · Pain · doi:10.1016/j.pain.2006.07.007 · Cited by 2 · see citing works
Flagged first, then by citations
3 of the 71 references couldn’t be matched to a known paper.
Cited by
Sorted by citations
Systematic review on intensive interdisciplinary pain treatment of children with chronic pain
Hechler, T., Kanstrup, M., Holley, A. L., Simons, L. E., Wicksell, R., Hirschfeld, G., & Zernikow, B. (2015) · Pediatrics · doi:10.1542/peds.2014-3319 · Cited by 230 · see citing works
Zernikow, B., Wager, J., Hechler, T., Hasan, C., Rohr, U., Dobe, M., Meyer, A., Hübner-Möhler, B., Wamsler, C., & Blankenburg, M. (2012) · BMC Pediatrics · doi:10.1186/1471-2431-12-54 · Cited by 214 · see citing works
Self-citationHechler, T., Ruhe, A., Schmidt, P., Hirsch, J., Wager, J., Dobe, M., Krummenauer, F., & Zernikow, B. (2013) · Pain · doi:10.1016/j.pain.2013.09.015 · Cited by 175 · see citing works
Logan, D. E., Carpino, E. A., Chiang, G., Condon, M., Firn, E., Gaughan, V. J., Hogan, M., Leslie, D. S., Olson, K., Sager, S., et al. (2012) · The Clinical Journal of Pain · doi:10.1097/ajp.0b013e3182457619 · Cited by 152 · see citing works
Managing Chronic Pain in Children and Adolescents: A Clinical Review
Landry, B. W., Fischer, P. R., Driscoll, S. W., Koch, K. M., Harbeck‐Weber, C., Mack, K. J., Wilder, R. T., Bauer, B. A., & Brandenburg, J. E. (2015) · PM&R · doi:10.1016/j.pmrj.2015.09.006 · Cited by 128 · see citing works
Pediatric pain management: The multidisciplinary approach
Odell, S., & Logan, D. (2013) · Journal of Pain Research · doi:10.2147/jpr.s37434 · Cited by 126 · see citing works
“However, programs with fewer hours dedicated to exercise have also demonstrated significant improvements in the functional abilities of their patients.(12,13,19,27)”
BackgroundSchool functioning and chronic pain: a review of methods and measures
Gorodzinsky, A. Y., Hainsworth, K. R., & Weisman, S. J. (2011) · Journal of Pediatric Psychology · doi:10.1093/jpepsy/jsr038 · Cited by 84 · see citing works
Chronic pain treatment in children and adolescents: less is good, more is sometimes better
Hechler, T., Wager, J., & Zernikow, B. (2014) · BMC Pediatrics · doi:10.1186/1471-2431-14-262 · Cited by 81 · see citing works
Hechler, T., Blankenburg, M. R., Dobe, M., Kosfelder, J., Hübner, B., & Zernikow, B. (2009) · European Journal of Pain · doi:10.1016/j.ejpain.2009.03.002 · Cited by 78 · see citing works
Priebe, J. A., Haas, K. K., Sanchez, L. F. M., Schoefmann, K., Utpadel-Fischler, D., Stockert, P., Thoma, R., Schießl, C., Kerkemeyer, L., Amelung, V. E., et al. (2020) · Journal of Pain Research · doi:10.2147/jpr.s260761 · Cited by 77 · see citing works
Ruskin, D. A., Lalloo, C., Amaria, K., Stinson, J., Kewley, E., Campbell, F. A., Brown, S. C., Jeavons, M., & McGrath, P. A. (2014) · Pain Research and Management · doi:10.1155/2014/856513 · Cited by 76 · see citing works
Hirschfeld, G. H. F., Hechler, T., Dobe, M., Wager, J., von Lützau, P., Blankenburg, M. R., Kosfelder, J., & Zernikow, B. (2012) · Journal of Pediatric Psychology · doi:10.1093/jpepsy/jss115 · Cited by 69 · see citing works
Dysvik, E., Kvaløy, J. T., Stokkeland, R., & Natvig, G. K. (2009) · International Journal of Nursing Studies · doi:10.1016/j.ijnurstu.2009.12.001 · Cited by 69 · see citing works
Hechler, T., Martín, A. P., Blankenburgl, M., Schroederl, S., Kosfelderl, J., Hölscherl, L., Deneckel, H., & Zernikow, B. (2011) · European Journal of Pain · doi:10.1016/j.ejpain.2011.03.001 · Cited by 65 · see citing works
Classifying the severity of paediatric chronic pain – an application of the chronic pain grading
Wager, J., Hechler, T., Darlington, A., Hirschfeld, G. H. F., Vocks, S., & Zernikow, B. (2013) · European Journal of Pain · doi:10.1002/j.1532-2149.2013.00314.x · Cited by 64 · see citing works
Stahlschmidt, L., Zernikow, B., & Wager, J. (2016) · Children · doi:10.3390/children3040033 · Cited by 63 · see citing works
Evaluation einer multimodalen Schmerztherapie am UniversitätsSchmerzCentrum Dresden
Schütze, A., Kaiser, U., Ettrich, U., Große, K., Goßrau, G., Schiller, M., Pöhlmann, K., Brannasch, K., Scharnagel, R., & Sabatowski, R. (2009) · Der Schmerz · doi:10.1007/s00482-009-0827-0 · Cited by 62 · see citing works
Zernikow, B., Ruhe, A.-K., Stahlschmidt, L., Schmidt, P., Staratzke, T., Frosch, M., & Wager, J. (2018) · Pain Medicine · doi:10.1093/pm/pnx067 · Cited by 61 · see citing works
Self-citationLogan, D. E., Conroy, C., Sieberg, C. B., & Simons, L. E. (2012) · Pain · doi:10.1016/j.pain.2012.05.027 · Cited by 61 · see citing works
Claus, B. B., Stahlschmidt, L., Dunford, E., Major, J., Harbeck-Weber, C., Bhandari, R. P., Baerveldt, A., Neß, V., Grochowska, K., Hübner-Möhler, B., et al. (2022) · Pain · doi:10.1097/j.pain.0000000000002636 · Cited by 59 · see citing works
Self-citationKozlowska, K., English, M., Savage, B., & Chudleigh, C. (2012) · American Journal of Family Therapy · doi:10.1080/01926187.2012.677715 · Cited by 57 · see citing works
Hechler, T., Kosfelder, J., Vocks, S., Mönninger, T., Blankenburg, M. R., Dobe, M., Gerlach, A. L., Denecke, H., & Zernikow, B. (2010) · Journal of Pain · doi:10.1016/j.jpain.2009.09.002 · Cited by 54 · see citing works
Schmerztherapie bei chronisch schmerzkranken, schwer beeinträchtigten Kindern und Jugendlichen
Dobe, M., Hechler, T., Behlert, J., Kosfelder, J., & Zernikow, B. (2011) · Der Schmerz · doi:10.1007/s00482-011-1051-2 · Cited by 50 · see citing works
Jaaniste, T., Noel, M. E., & von Baeyer, C. L. (2016) · Pain · doi:10.1097/j.pain.0000000000000666 · Cited by 46 · see citing works
Shaygan, M., & Jaberi, A. (2021) · Scientific Reports · doi:10.1038/s41598-021-86156-8 · Cited by 44 · see citing works
The Influence of Anxiety Reduction on Clinical Response to Pediatric Chronic Pain Rehabilitation
Benore, E. R., D’Auria, A., Banez, G. A., Worley, S. E., & Tang, A. (2014) · Clinical Journal of Pain · doi:10.1097/ajp.0000000000000127 · Cited by 42 · see citing works
Dysvik, E., Kvaløy, J. T., & Natvig, G. K. (2011) · Journal of Advanced Nursing · doi:10.1111/j.1365-2648.2011.05810.x · Cited by 41 · see citing works
Hechler, T., Dobe, M., & Zernikow, B. (2009) · Journal of Pediatric Psychology · doi:10.1093/jpepsy/jsp066 · Cited by 41 · see citing works
Stein, K. F., & Miclescu, A. A. (2013) · Scandinavian Journal of Pain · doi:10.1016/j.sjpain.2013.06.003 · Cited by 37 · see citing works
Zernikow, B., Gerhold, K., Bürk, G., Häuser, W., Hinze, C. H., Hospach, T., Illhardt, A., Mönkemöller, K., Richter, M., Schnöbel-Müller, E., et al. (2012) · Der Schmerz · doi:10.1007/s00482-012-1168-y · Cited by 37 · see citing works
Randall, E. T., Smith, K. R., Conroy, C., Smith, A. M., Sethna, N., & Logan, D. E. (2018) · The Clinical Journal of Pain · doi:10.1097/ajp.0000000000000616 · Cited by 37 · see citing works
Bitte nicht noch mehr verletzen!
Zernikow, B., Dobe, M., Hirschfeld, G. H. F., Blankenburg, M. R., Reuther, M., & Maier, C. (2012) · Der Schmerz · doi:10.1007/s00482-012-1164-2 · Cited by 36 · see citing works
Axtner, J., Steele, M. L., Kröz, M., Spahn, G., Matthes, H., & Schad, F. (2016) · BMC Cancer · doi:10.1186/s12885-016-2594-5 · Cited by 35 · see citing works
Pielech, M., Lunde, C. E., Becker, S. J., Vowles, K. E., & Sieberg, C. B. (2020) · American Psychologist · doi:10.1037/amp0000655 · Cited by 36 · see citing works
Management of chronic pain through pain management programmes
Wilson, I. R. (2017) · British Medical Bulletin · doi:10.1093/bmb/ldx032 · Cited by 36 · see citing works
Hechler, T., Dobe, M., Damschen, U., Blankenburg, M., Schroeder, S., Kosfelder, J., & Zernikow, B. (2010) · Pain Medicine · doi:10.1111/j.1526-4637.2010.00839.x · Cited by 34 · see citing works
Bruce, B. K., Harrison, T. E., Bee, S. M., Luedtke, C. A., Porter, C.-B. J., Fischer, P. R., Hayes, S. E., Allman, D. A., Ale, C. M., & Weiss, K. E. (2016) · Clinical Pediatrics · doi:10.1177/0009922816638663 · Cited by 31 · see citing works
Cotton, S., Luberto, C. M., Bogenschutz, L. H., Pelley, T. J., & Dusek, J. A. (2013) · The Journal of Alternative and Complementary Medicine · doi:10.1089/acm.2013.0306 · Cited by 30 · see citing works
Vetter, T. R., McGwin, G., Bridgewater, C. L., Madan‐Swain, A., & Ascherman, L. I. (2013) · Pain Research and Treatment · doi:10.1155/2013/143292 · Cited by 30 · see citing works
Rapid identification and clinical indices of fear-avoidance in youth with chronic pain
Heathcote, L. C., Bhandari, R. P., Timmers, I., Harrison, L. E., & Simons, L. E. (2019) · Pain · doi:10.1097/j.pain.0000000000001742 · Cited by 29 · see citing works
A Pilot Exploration of Symptom Trajectories in Adolescents with Cancer during Chemotherapy
Ameringer, S., Elswick, R. K., Shockey, D., & Dillon, R. (2013) · Cancer Nursing · doi:10.1097/ncc.0b013e318250da1a · Cited by 28 · see citing works
Household income determines access to specialized pediatric chronic pain treatment in Germany
Ruhe, A., Wager, J., Hirschfeld, G. H. F., & Zernikow, B. (2016) · BMC Health Services Research · doi:10.1186/s12913-016-1403-9 · Cited by 28 · see citing works
Draheim, N., Ebinger, F., Schnöbel-Müller, E., Wolf, B., & Häuser, W. (2017) · Der Schmerz · doi:10.1007/s00482-017-0208-z · Cited by 28 · see citing works
Schmerzempfindung bei Jugendlichen mit chronischen funktionellen Schmerzen
Wager, J., Tietze, A.-L., Denecke, H., Schroeder, S., Vocks, S., Kosfelder, J., Zernikow, B., & Hechler, T. (2010) · Der Schmerz · doi:10.1007/s00482-010-0920-4 · Cited by 27 · see citing works
Pain Therapy in Children and Adolescents
Zernikow, B., & Hechler, T. (2008) · Deutsches Ärzteblatt international · doi:10.3238/arztebl.2008.0511 · Cited by 27 · see citing works
Health Care Utilization and Cost in Children and Adolescents With Chronic Pain
Ruhe, A., Frosch, M., Wager, J., Linder, R., Pfenning, I., Sauerland, D., & Zernikow, B. (2016) · Clinical Journal of Pain · doi:10.1097/ajp.0000000000000460 · Cited by 26 · see citing works
Parenting in the Context of Children’s Chronic Pain: Balancing Care and Burden
Guite, J. W., Russell, B. S., Homan, K. J., Tepe, R. M., & Williams, S. E. (2018) · Children · doi:10.3390/children5120161 · Cited by 26 · see citing works
Simons, L. E., Harrison, L. E., O'Brien, S. F., Heirich, M. S., Loecher, N., Boothroyd, D. B., Vlaeyen, J. W. S., Wicksell, R. K., Schofield, D., Hood, K. K., et al. (2019) · Contemporary Clinical Trials Communications · doi:10.1016/j.conctc.2019.100448 · Cited by 24 · see citing works
Kempert, H., Benore, E. R., & Heines, R. (2016) · Archives of Physical Medicine and Rehabilitation · doi:10.1016/j.apmr.2016.08.471 · Cited by 24 · see citing works
Dekker, C., Goossens, M. E. J. B., Bastiaenen, C. H. G., & Verbunt, J. A. M. C. F. (2016) · BMC Musculoskeletal Disorders · doi:10.1186/s12891-016-1178-5 · Cited by 23 · see citing works
Identifying subgroups of paediatric chronic pain patients: A cluster‐analytic approach
Wager, J., Zernikow, B., Darlington, A., Vocks, S., & Hechler, T. (2014) · European Journal of Pain · doi:10.1002/j.1532-2149.2014.497.x · Cited by 22 · see citing works
Junghans-Rutelonis, A. N., Craner, J. R., Ale, C. M., Harbeck‐Weber, C., Fischer, P. R., & Weiss, K. (2018) · Journal of Clinical Psychology in Medical Settings · doi:10.1007/s10880-018-9558-7 · Cited by 22 · see citing works
Benore, E. R., Webster, E. E., Wang, L., & Banez, G. A. (2018) · Headache The Journal of Head and Face Pain · doi:10.1111/head.13389 · Cited by 20 · see citing works
Development of an Interdisciplinary Pediatric Pain Rehabilitation Program
Bruce, B. K., Weiss, K. E., Ale, C. M., Harrison, T. E., & Fischer, P. R. (2017) · Mayo Clinic Proceedings Innovations Quality & Outcomes · doi:10.1016/j.mayocpiqo.2017.05.006 · Cited by 19 · see citing works
Dogan, M., Hirschfeld, G. H. F., Blankenburg, M. R., Frühwald, M. C., Ahnert, R., Braun, S., Marschall, U., Pfenning, I., Zernikow, B., & Wager, J. (2021) · JAMA Network Open · doi:10.1001/jamanetworkopen.2021.27024 · Cited by 19 · see citing works
Influence of parental occupation on access to specialised treatment for paediatric chronic pain
Wager, J., Ruhe, A., Hirschfeld, G. H. F., Wamsler, C., Dobe, M., Hechler, T., & Zernikow, B. (2013) · Der Schmerz · doi:10.1007/s00482-013-1320-3 · Cited by 19 · see citing works
Celedon, X., Amari, A., Ward, C. M., Prestwich, S., & Slifer, K. J. (2014) · Current Physical Medicine and Rehabilitation Reports · doi:10.1007/s40141-014-0047-0 · Cited by 17 · see citing works
Novel Interventions in Children’s Healthcare for Youth Hospitalized for Chronic Pain
Harris, M. A., Wagner, D. V., Wilson, A. C., Spiro, K., Heywood, M., & Hoehn, D. (2015) · Clinical Practice in Pediatric Psychology · doi:10.1037/cpp0000088 · Cited by 17 · see citing works
Is there a right control condition in mHealth trials? A critical view on pain medicine
Priebe, J. A., & Toelle, T. R. (2019) · npj Digital Medicine · doi:10.1038/s41746-019-0184-z · Cited by 16 · see citing works
Inpatient Management of Migraine
Marmura, M. J., & Goldberg, S. W. (2015) · Current Neurology and Neuroscience Reports · doi:10.1007/s11910-015-0539-z · Cited by 15 · see citing works
Dekker, C., Goossens, M. E. J. B., Winkens, B., Remerie, S. C., Bastiaenen, C. H. G., & Verbunt, J. (2020) · Children · doi:10.3390/children7120288 · Cited by 14 · see citing works
Westendorp, T., Verbunt, J., Remerie, S. C., de Blécourt, A. C. E., Baalen, B. V., & Smeets, R. (2016) · European Journal of Pain · doi:10.1002/ejp.836 · Cited by 14 · see citing works
Pain in child patients: A review on managements
Dezfouli, S. M. M., & Khosravi, S. (2020) · European Journal of Translational Myology · doi:10.4081/ejtm.2020.8712 · Cited by 13 · see citing works
Dobe, M., Hechler, T., & Zernikow, B. (2009) · Journal of Child & Adolescent Trauma · doi:10.1080/19361520903317287 · Cited by 13 · see citing works
Kempert, H., Benore, E. R., & Heines, R. (2016) · Scandinavian Journal of Pain · doi:10.1016/j.sjpain.2016.10.004 · Cited by 13 · see citing works
Multimodale Therapieprogramme für chronische Schmerzen
Köpf, A., & Gjoni, E. (2015) · Der Anaesthesist · doi:10.1007/s00101-014-2418-4 · Cited by 13 · see citing works
Harrison, L. E., Webster, S. N., Orden, A. R. V., Choate, E., Jehl, N. M., Stinson, J., Wicksell, R. K., Darnall, B. D., & Simons, L. E. (2022) · BMJ Open · doi:10.1136/bmjopen-2022-065997 · Cited by 13 · see citing works
Hermann, C. (2011) · Pain Management · doi:10.2217/pmt.11.48 · Cited by 12 · see citing works
Hurtubise, K., Blais, S., Noel, M. E., Brousselle, A., Dallaire, F., Rasic, N. F., & Camden, C. (2020) · Clinical Journal of Pain · doi:10.1097/ajp.0000000000000869 · Cited by 11 · see citing works
Multidisciplinary Treatment for Adolescents with Chronic Pain and/or Fatigue: Who Will Benefit?
Westendorp, T., Verbunt, J., de Groot, I. J. M., Remerie, S. C., ter Steeg, A. M., & Smeets, R. (2016) · Pain Practice · doi:10.1111/papr.12495 · Cited by 10 · see citing works
Schmerzmedizinische Versorgung chronisch schmerzkranker Kinder und Jugendlicher in Deutschland
Höfel, L., Draheim, N., Haas, J., & Ebinger, F. (2020) · Der Schmerz · doi:10.1007/s00482-020-00510-9 · Cited by 9 · see citing works
Farré, A., Lunt, L. E., Lee, R. R., Verstappen, S. M. M., & McDonagh, J. E. R. (2023) · Patient Education and Counseling · doi:10.1016/j.pec.2023.107765 · Cited by 8 · see citing works
The Hospital-Based Consultation and Liaison Service
Ernst, M. M., Piazza‐Waggoner, C., Chabon, B., Murphy, M. K., Carey, J., & Roddenberry, A. (2014) · Springer eBooks · doi:10.1007/978-0-387-09817-3_16 · Cited by 8 · see citing works
Major, J., Varga, Z., Gyimesi-Szikszai, A., & Ádám, S. (2017) · Journal of Child Health Care · doi:10.1177/1367493517697479 · Cited by 8 · see citing works
Inpatient Management of Migraine
Marmura, M. J., & Hou, A. (2019) · Neurologic Clinics · doi:10.1016/j.ncl.2019.07.007 · Cited by 7 · see citing works
Hurtubise, K., Brousselle, A., & Camden, C. (2020) · Paediatric and Neonatal Pain · doi:10.1002/pne2.12018 · Cited by 7 · see citing works
Fibromyalgia syndrome Definition, classification, clinical diagnosis and prognosis
Maximilians-University Munich (2012) · Cited by 7 · see citing works
Chronische Kopfschmerzen bei Kindern und Jugendlichen
Blankenburg, M. R., Schroth, M. A., & Braun, S. (2018) · Klinische Pädiatrie · doi:10.1055/a-0710-5014 · Cited by 7 · see citing works
Krietsch, K. N., Beebe, D. W., King, C. D., Homan, K. J., & Williams, S. E. (2021) · Children · doi:10.3390/children8010042 · Cited by 7 · see citing works
Pain in child patients: A review on managements
Dezfouli, S. M. M., & Khosravi, S. (2020) · European Journal of Translational Myology · doi:10.4081/ejtm.2019.8712 · Cited by 7 · see citing works
Champion, J., Crawford, M., & Jaaniste, T. (2023) · Children · doi:10.3390/children10020357 · Cited by 6 · see citing works
Chronische muskuloskelettale Schmerzen bei Kindern und Jugendlichen
Haas, J. (2009) · Monatsschrift Kinderheilkunde · doi:10.1007/s00112-009-1959-0 · Cited by 6 · see citing works
Angulo, N. R. D., Debeaurepaire, C. A., Deprez, A., Tanche, L., Pavageau, V., Hamain, A., Grave, C., Yatzimirsky, A., Vallée, L., & Avez‐Couturier, J. (2016) · Archives de Pédiatrie · doi:10.1016/j.arcped.2016.05.016 · Cited by 5 · see citing works
Dogan, M., Zernikow, B., & Wager, J. (2021) · Children · doi:10.3390/children8030220 · Cited by 5 · see citing works
Kinderschmerzzentrum, D., Medizin, I., & Saarbrücken, K. (2012) · Cited by 4 · see citing works
Geschlechtsspezifische Ergebnisse des Dresdner Kinder- und Jugendkopfschmerzprogrammes DreKiP
Zaranek, L., Sobe, H., Richter, M., Hübler, A., Berner, R., von der Hagen, M., Koch, T., Sabatowski, R., Klimová, A., & Goßrau, G. (2023) · Der Schmerz · doi:10.1007/s00482-023-00756-z · Cited by 4 · see citing works
Cruz, C., Chudleigh, C., Savage, B., & Kozlowska, K. (2014) · Australian and New Zealand Journal of Family Therapy · doi:10.1002/anzf.1059 · Cited by 4 · see citing works
Pain Amplification Syndrome: A Biopsychosocial Approach
Namerow, L. B., Kutner, E. C., Wakefield, E. C., Rzepski, B., & Sahl, R. A. (2016) · Seminars in Pediatric Neurology · doi:10.1016/j.spen.2016.10.006 · Cited by 4 · see citing works
Frosch, M., & Zernikow, B. (2015) · Springer eBooks · doi:10.1007/978-3-662-45057-4_16 · Cited by 4 · see citing works
Is It All Worthwhile? – Effectiveness of Intensive Interdisciplinary Pain Treatment
Hechler, T., Dobe, M., & Zernikow, B. (2013) · Springer eBooks · doi:10.1007/978-3-642-37816-4_8 · Cited by 3 · see citing works
Bausteine des Schmerztherapieprogramms
Dobe, M., Hartmann, R., Kriszio, H., Behlert, J., & Zernikow, B. (2012) · Springer eBooks · doi:10.1007/978-3-642-32671-4_6 · Cited by 3 · see citing works
Chronische Kopf-, Bauch- oder Gelenkschmerzen
Blankenburg, M. R., Kriszio, H., Humberg, A., & Frosch, M. (2013) · Monatsschrift Kinderheilkunde · doi:10.1007/s00112-013-2959-7 · Cited by 3 · see citing works
Effektivität einer individualisierten, multimodalen Behandlung bei chronischen Schmerzpatienten
Careddu, S., Ljutow, A., & Reichmuth, N. (2021) · Der Schmerz · doi:10.1007/s00482-021-00558-1 · Cited by 3 · see citing works
Gierthmühlen, J., Baron, R., Blankenburg, M. R., Zernikow, B., & Maier, C. (2016) · PAIN Reports · doi:10.1097/pr9.0000000000000578 · Cited by 3 · see citing works
Diagnostics of Chronic Pain in Children and Adolescents
Wager, J., Kriszio, H., Dobe, M., Hechler, T., & Zernikow, B. (2013) · Springer eBooks · doi:10.1007/978-3-642-37816-4_3 · Cited by 3 · see citing works
Wakefield, E. O., & Jerson, B. (2017) · Topics in Pain Management · doi:10.1097/01.tpm.0000515416.01386.7d · Cited by 2 · see citing works
Bausteine des Schmerztherapieprogramms
Dobe, M., Frosch, M., Flack, F., Behlert, J., & Zernikow, B. (2019) · Springer eBooks · doi:10.1007/978-3-662-58248-0_6 · Cited by 2 · see citing works
Junghans-Rutelonis, A. N., Weiss, K., Tamula, M. A., Karvounides, D., Harbeck‐Weber, C., & Martin, S. C. (2017) · Professional Psychology Research and Practice · doi:10.1037/pro0000156 · Cited by 2 · see citing works
Yang, J. J., Wang, Z., Trucco, E. M., Buu, A., & Lin, H. (2021) · The American Journal of Drug and Alcohol Abuse · doi:10.1080/00952990.2021.1977311 · Cited by 1 · see citing works
Andias, R., Rodrigues, M., & Silva, A. G. (2024) · PM&R · doi:10.1002/pmrj.13131 · Cited by 1 · see citing works
- Authors
- Hechler, T., Dobe, M., Kosfelder, J., Damschen, U., Hübner, B., Blankenburg, M., Sauer, C., & Zernikow, B.
- Affiliations
- Vodafone Foundation (GB)
- Hochschule Düsseldorf University of Applied Sciences (DE)
- Corresponding author
- Hechler, Tanja
- Dobe, Michael
- Damschen, Uta
- Hübner, Bettina
- Blankenburg, Markus
- Zernikow, Boris
- Venue
- The Clinical Journal of Pain
- Published
- 2009-02
- Volume
- 25
- Issue
- 2
- Pages
- 156-166
- ISSN
- 0749-8047 (ISSN-L)
- OpenAlex
- W2019118209
- Cited by
- 130
- References
- 71
- Citations by year
- 2026: 1 · 2025: 2 · 2024: 2 · 2023: 4 · 2022: 2 · 2021: 6 · 2020: 8 · 2019: 10 · 2018: 5 · 2017: 8 · 2016: 14 · 2015: 7 · 2014: 7 · 2013: 19 · 2012: 16
- FWCI
- 9.96
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Clinical Journal of Pain (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Pediatrics, Perinatology and Child Health › Pediatric Pain Management Techniques
- Health Sciences › Medicine › Pharmacology › Musculoskeletal pain and rehabilitation
- Health Sciences › Medicine › Anesthesiology and Pain Medicine › Pain Management and Treatment
- Keywords
- chronic pain, adolescents, multimodal pain management, pain intensity, pain-related disability, emotional distress, headache, school absenteeism, pediatric pain
- MeSH terms
- Adolescent, Child, Chronic Disease, Combined Modality Therapy, Emotions, Female, Follow-Up Studies, Humans, Longitudinal Studies, Male, Pain, Severity of Illness Index, Reproducibility of Results, Treatment Outcome, Young Adult, Pain Management
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