A Replication of the Autism Diagnostic Observation Schedule (ADOS) Revised Algorithms
Open accessAbstract
Objective To replicate the factor structure and predictive validity of revised Autism Diagnostic Observation Schedule algorithms in an independent dataset (N = 1,282). Method Algorithm revisions were replicated using data from children ages 18 months to 16 years collected at 11 North American sites participating in the Collaborative Programs for Excellence in Autism and the Studies to Advance Autism Research and Treatment. Results Sensitivities and specificities approximated or exceeded those of the old algorithms except for young children with phrase speech and a clinical diagnosis of pervasive developmental disorders not otherwise specified. Conclusions Revised algorithms increase comparability between modules and improve the predictive validity of the Autism Diagnostic Observation Schedule for autism cases compared to the original algorithms.
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Not responding to one's name and not following another person's pointing gesture are strong predictors of autism in toddlers and younger preschool children but not in older children or adults.
“not responding to one's name and not following another person's pointing gesture point are strong predictors of autism in toddlers and younger preschool children but not in older children or adults (Gotham et al. 2007, 2008).”
From Recent Advances in Autism Research as Reflected in DSM-5 Criteria for Autism Spectrum Disorder (2015) · cites this paper as Gotham et al. 2008
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- Authors
- GOTHAM, K., RISI, S., DAWSON, G., TAGER-FLUSBERG, H., JOSEPH, R., CARTER, A., HEPBURN, S., McMAHON, W., RODIER, P., HYMAN, S. L., SIGMAN, M., ROGERS, S., LANDA, R., SPENCE, M. A., OSANN, K., FLODMAN, P., VOLKMAR, F., HOLLANDER, E., BUXBAUM, J., PICKLES, A., & LORD, C.
- Affiliations
- Boston University (US)
- Corresponding author
- GOTHAM, KATHERINE
- ORCID
- Venue
- Journal of the American Academy of Child & Adolescent Psychiatry
- Publisher
- Elsevier BV
- Published
- 2008-06
- Volume
- 47
- Issue
- 6
- Pages
- 642-651
- ISSN
- 0890-8567 (ISSN-L)
- PMC
- PMC3057666
- OpenAlex
- W2034529431
- Cited by
- 374
- References
- 21
- Citations by year
- 2026: 8 · 2025: 5 · 2024: 4 · 2023: 8 · 2022: 18 · 2021: 17 · 2020: 17 · 2019: 22 · 2018: 17 · 2017: 19 · 2016: 24 · 2015: 26 · 2014: 27 · 2013: 34 · 2012: 49
- FWCI
- 11.75
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Journal of the American Academy of Child & Adolescent Psychiatry (publishedVersion)
- PubMed (publishedVersion)
- PubMed Central (acceptedVersion)
- Research Portal (King's College London) (submittedVersion)
- Research Explorer (The University of Manchester) (submittedVersion)
- Funders
- NIMH (RO1 MH066469, NIMH R25MH067723)
- Topics
- Life Sciences › Neuroscience › Cognitive Neuroscience › Autism Spectrum Disorder Research
- Health Sciences › Medicine › Psychiatry and Mental health › Child Nutrition and Feeding Issues
- Social Sciences › Decision Sciences › Management Science and Operations Research › Psychometric Methodologies and Testing
- Keywords
- Autism Diagnostic Observation Schedule, replication, factor structure, predictive validity, sensitivity and specificity, young children, autism diagnosis
- MeSH terms
- Algorithms, Autistic Disorder, Child, Developmental Disabilities, Child Development Disorders, Pervasive, Child, Preschool, Diagnosis, Differential, Down Syndrome, Female, Humans, Male, Personality Assessment, Psychometrics, Reproducibility of Results
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
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