Cited by 375Autism Spectrum Disorder ResearchChild Nutrition and Feeding IssuesPsychometric Methodologies and Testing

A Replication of the Autism Diagnostic Observation Schedule (ADOS) Revised Algorithms

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GOTHAM, KATHERINE, RISI, SUSAN, DAWSON, GERALDINE, TAGER-FLUSBERG, HELEN, JOSEPH, ROBERT, CARTER, ALICE, HEPBURN, SUSAN, McMAHON, WILLIAM +13 more·2008·Journal of the American Academy of Child & Adolescent Psychiatry

Abstract

Objective To replicate the factor structure and predictive validity of revised Autism Diagnostic Observation Schedule algorithms in an independent dataset (N = 1,282). Method Algorithm revisions were replicated using data from children ages 18 months to 16 years collected at 11 North American sites participating in the Collaborative Programs for Excellence in Autism and the Studies to Advance Autism Research and Treatment. Results Sensitivities and specificities approximated or exceeded those of the old algorithms except for young children with phrase speech and a clinical diagnosis of pervasive developmental disorders not otherwise specified. Conclusions Revised algorithms increase comparability between modules and improve the predictive validity of the Autism Diagnostic Observation Schedule for autism cases compared to the original algorithms.

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Crossref · 10.1097/chi.0b013e31816bffb7

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  • Not responding to one's name and not following another person's pointing gesture are strong predictors of autism in toddlers and younger preschool children but not in older children or adults.

    “not responding to one's name and not following another person's pointing gesture point are strong predictors of autism in toddlers and younger preschool children but not in older children or adults (Gotham et al. 2007, 2008).”

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Authors
GOTHAM, K., RISI, S., DAWSON, G., TAGER-FLUSBERG, H., JOSEPH, R., CARTER, A., HEPBURN, S., McMAHON, W., RODIER, P., HYMAN, S. L., SIGMAN, M., ROGERS, S., LANDA, R., SPENCE, M. A., OSANN, K., FLODMAN, P., VOLKMAR, F., HOLLANDER, E., BUXBAUM, J., PICKLES, A., & LORD, C.
Affiliations
Boston University (US)
Corresponding author
GOTHAM, KATHERINE
Venue
Journal of the American Academy of Child & Adolescent Psychiatry
Publisher
Elsevier BV
Published
2008-06
Volume
47
Issue
6
Pages
642-651
ISSN
0890-8567 (ISSN-L)
OpenAlex
W2034529431
Cited by
374
References
21
Citations by year
2026: 8 · 2025: 5 · 2024: 4 · 2023: 8 · 2022: 18 · 2021: 17 · 2020: 17 · 2019: 22 · 2018: 17 · 2017: 19 · 2016: 24 · 2015: 26 · 2014: 27 · 2013: 34 · 2012: 49
FWCI
11.75
Type
journal article
Language
en
Open access
Locations
  • Journal of the American Academy of Child & Adolescent Psychiatry (publishedVersion)
  • PubMed (publishedVersion)
  • PubMed Central (acceptedVersion)
  • Research Portal (King's College London) (submittedVersion)
  • Research Explorer (The University of Manchester) (submittedVersion)
Funders
NIMH (RO1 MH066469, NIMH R25MH067723)
Topics
  • Life Sciences › Neuroscience › Cognitive Neuroscience › Autism Spectrum Disorder Research
  • Health Sciences › Medicine › Psychiatry and Mental health › Child Nutrition and Feeding Issues
  • Social Sciences › Decision Sciences › Management Science and Operations Research › Psychometric Methodologies and Testing
Keywords
Autism Diagnostic Observation Schedule, replication, factor structure, predictive validity, sensitivity and specificity, young children, autism diagnosis
MeSH terms
Algorithms, Autistic Disorder, Child, Developmental Disabilities, Child Development Disorders, Pervasive, Child, Preschool, Diagnosis, Differential, Down Syndrome, Female, Humans, Male, Personality Assessment, Psychometrics, Reproducibility of Results

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