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Cited by 77Attention Deficit Hyperactivity DisorderDevelopmental and Educational NeuropsychologyBehavioral and Psychological Studies

Effects of MPH-OROS on the Organizational, Time Management, and Planning Behaviors of Children With ADHD

Abikoff, Howard, Nissley-Tsiopinis, Jenelle, Gallagher, Richard, Zambenedetti, Maurizio, Seyffert, Michael, Boorady, Roy, McCarthy, John·2009·Journal of the American Academy of Child & Adolescent Psychiatry
DOI 10.1097/chi.0b013e3181930626
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Abstract

Objective To evaluate the effects of stimulant medication on organizational, time management, and planning (OTMP) in children with attention-deficit/hyperactivity disorder (ADHD) and ascertain whether OTMP is normalized with medication.Method Participants included 19 stimulant-naïve children with ADHD (aged 8-13 years) and impaired OTMP functioning, defined as greater than 1 SD below norms on the Children's Organizational Skills Scale. A double-blind, placebo-controlled, crossover design, with 4 weeks of each condition, evaluated medication (methylphenidate-osmotic-release oral system [MPH-OROS]) effects on OTMP, based on the parent and teacher versions of the Children's Organizational Skills Scale. The parent and teacher Swanson, Nolan, and Pelham, Version IV, rating scales assessed ADHD symptoms. "Not impaired" in OTMP was defined as no longer meeting study entry criteria, and "not impaired" in ADHD symptoms was defined as having mean Swanson, Nolan, and Pelham, Version IV, scores of < or = 1.0.Results MPH-OROS significantly improved children's OTMP behaviors. These improvements were correlated with significant reductions in ADHD symptoms. However, most of the children (61%) continued to show significant OTMP impairments on MPH-OROS.Conclusions The MPH-OROS reduced children's OTMP deficits, and these improvements were associated with improvements in ADHD symptoms. Some children remained impaired in OTMP even after effective stimulant treatment of ADHD symptoms. These youngsters may require other treatments that target OTMP deficits.

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  • Without proper interventions, functional impairments in time management, planning/organizing, and prosocial behavior skills often endure and escalate into adolescence and adulthood.

    “Without proper interventions, functional impairments in the areas of time management, planning/organizing, and prosocial behavior skills often endure and escalate into adolescence and adulthood [6,7,11-14].”

    From Behavioral Outcome Effects of Serious Gaming as an Adjunct to Treatment for Children with Attention-Deficit/Hyperactivity Disorder: A Randomized Controlled Trial (2016) · cites this paper as [6]

  • Compared to children without the disorder, children with ADHD have more difficulties at school making schedules to finish assignments on time, executing complex planning tasks, organizing material needed for assignments, remembering task instructions, and setting priorities.

    “Compared to children without the disorder, children with ADHD have more difficulties at school making schedules to finish assignments on time, executing complex planning tasks, organizing material needed for assignments, remembering task instructions, and setting priorities [6,7].”

    From Behavioral Outcome Effects of Serious Gaming as an Adjunct to Treatment for Children with Attention-Deficit/Hyperactivity Disorder: A Randomized Controlled Trial (2016) · cites this paper as [6]

  • OROS methylphenidate lessens ADHD symptoms throughout the day and has greater adherence, thought associated with convenience of once-daily dosing.

    “Research has continued to suggest that osmotic-release oral system (OROS) methylphenidate lessens ADHD symptoms throughout the day and has greater adherence, thought to be associated with the convenience of once-daily dosing [39-41].”

    From Advances in understanding and treating ADHD (2011) · cites this paper as [41]

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Authors
Abikoff, H., Nissley-Tsiopinis, J., Gallagher, R., Zambenedetti, M., Seyffert, M., Boorady, R., & McCarthy, J.
Affiliations
Cornell University (US)
Corresponding author
Abikoff, Howard
ORCID
Venue
Journal of the American Academy of Child & Adolescent Psychiatry
Publisher
Elsevier BV
Published
2009-02
Volume
48
Issue
2
Pages
166-175
ISSN
0890-8567 (ISSN-L)
DOI
10.1097/chi.0b013e3181930626
OpenAlex
W2077085767
Semantic Scholar
65f8895d5d24548d448b16f26038dbc181653747
Cited by
77
References
64
Citations by year
2026: 3 · 2025: 3 · 2024: 2 · 2023: 8 · 2022: 3 · 2021: 5 · 2020: 4 · 2018: 2 · 2017: 11 · 2016: 5 · 2015: 5 · 2014: 7 · 2013: 1 · 2012: 6
FWCI
3.70
Type
journal article
Language
en
Open access
closed
Licence
www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Locations
  • Journal of the American Academy of Child & Adolescent Psychiatry (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Psychiatry and Mental health › Attention Deficit Hyperactivity Disorder
  • Social Sciences › Psychology › Neuropsychology and Physiological Psychology › Developmental and Educational Neuropsychology
  • Social Sciences › Psychology › Developmental and Educational Psychology › Behavioral and Psychological Studies
Keywords
methylphenidate, osmotic-release oral system, attention deficit hyperactivity disorder, organizational skills, time management, planning skills, stimulant medication, ADHD symptoms, children
MeSH terms
Administration, Oral, Adolescent, Central Nervous System Stimulants, Attention Deficit Disorder with Hyperactivity, Child, Double-Blind Method, Female, Humans, Male, Methylphenidate, Psychiatric Status Rating Scales, Drug Delivery Systems, Treatment Outcome, Time Management, Cross-Over Studies

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