The DOI matches its Crossref record; 14 of the 14 references it cites were found in a registry or an index.
A conduit to metastasis: circulating tumor cell biology
Open accessAbstract
Advances in the enrichment and analysis of rare cells from the bloodstream have allowed for detection and characterization of circulating tumor cells (CTCs) from patients with cancer. The analysis of CTCs has provided significant insight into the metastatic process. Studies on the biology of CTCs have begun to elucidate the molecular mechanisms of CTC generation, intravasation, survival, interactions with components of the blood, extravasation, and colonization of distant organs. Additionally, the study of CTCs has exposed dramatic intrapatient and interpatient heterogeneity and their evolution over time. In this review, we focus on the current knowledge of CTC biology and the potential clinical implications.
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Cites
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BackgroundGenes that mediate breast cancer metastasis to lung
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Self-citationMacrophages Regulate the Angiogenic Switch in a Mouse Model of Breast Cancer
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Cited by
Ganesh, K., & Massagué, J. (2021) · Nature Medicine · doi:10.1038/s41591-020-01195-4 · Cited by 1,051
Bui, T. M., Wiesolek, H. L., & Sumagin, R. (2020) · Journal of Leukocyte Biology · doi:10.1002/jlb.2mr0220-549r · Cited by 957
Signaling pathways involved in colorectal cancer: pathogenesis and targeted therapy
Li, Q., Geng, S., Luo, H., Wang, W., Mo, Y.-Q., Luo, Q., Wang, L., Song, G.-B., Sheng, J.-P., & Xu, B. (2024) · Signal Transduction and Targeted Therapy · doi:10.1038/s41392-024-01953-7 · Cited by 546
The Extracellular Matrix Modulates the Metastatic Journey
Kai, F., Drain, A. P., & Weaver, V. M. (2019) · Developmental Cell · doi:10.1016/j.devcel.2019.03.026 · Cited by 537
The functional activity of E-cadherin controls tumor cell metastasis at multiple steps
Na, T.-Y., Schecterson, L., Mendonsa, A. M., & Gumbiner, B. M. (2020) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1918167117 · Cited by 441
Metadata
- Authors
- Micalizzi, D. S., Maheswaran, S., & Haber, D. A.
- Venue
- Genes & Development
- Publisher
- Cold Spring Harbor Laboratory
- Published
- 2017-09-15
- Volume
- 31
- Issue
- 18
- Pages
- 1827-1840
- ISSN
- 0890-9369 (ISSN-L)
- 1549-5477
- OpenAlex
- W2765792772
- Cited by
- 446
- References
- 14
- Type
- posted content
- Language
- en
- Open access
- diamond
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
