DNA methylation patterns and epigenetic memory
Cited by (1,038)
Items 101–200 of 1,038
- Epigenetics in health and diseaseZhang, Lian, Lu, Qianjin, Chang, Christopher · 2020 · Advances in Experimental Medicine and Biology
- Mechanisms and functions of Tet protein-mediated 5-methylcytosine oxidationHao Wu, Yi Zhang · 2011 · Genes & Development
- DNA methylation analysis by pyrosequencingJörg Tost, Ivo Glynne Gut · 2007 · Nature Protocols
- DNA methylation and histone modifications: teaming up to silence genesFrançois Fuks · 2005 · Current Opinion in Genetics & Development
- Resistance of IAPs to methylation reprogramming may provide a mechanism for epigenetic inheritance in the mouseLane, Natasha, Dean, Wendy, Erhardt, Sylvia, Hajkova, Petra, Surani, Azim, Walter, Jörn, Reik, Wolf · 2003 · genesis
- A Novel CpG Island Set Identifies Tissue-Specific Methylation at Developmental Gene LociRobert Scott Illingworth, Alastair R. W. Kerr, Dina DeSousa, Helle Færk Jørgensen, Peter Ellis, Jim Stalker, David K. Jackson, Chris M. Clee, R. W. Plumb, Jane Rogers et al. · 2008 · PLoS Biology
- High-throughput DNA methylation profiling using universal bead arraysMarina V. Bibikova, Zhenwu Lin, Lixin Zhou, Eugene Chudin, Eliza Wickham‐Garcia, Bonnie Wu, Dennis Doucet, Neal J. Thomas, Yunhua Wang, Ekkehard Vollmer et al. · 2006 · Genome Research
- Epigenetic interplay between histone modifications and DNA methylation in gene silencingThomas Vaissière, Carla Sawan, Zdenko Herceg · 2008 · Mutation Research/Reviews in Mutation Research
- Activity-Regulated Transcription: Bridging the Gap between Neural Activity and BehaviorYap, Ee-Lynn, Greenberg, Michael E. · 2018 · Neuron
- Epigenetic Gene Regulation in the Bacterial WorldJosep Casadesús, David A. Low · 2006 · Microbiology and Molecular Biology Reviews
- A Bayesian deconvolution strategy for immunoprecipitation-based DNA methylome analysisThomas A. Down, Vardhman K. Rakyan, Dann Turner, Paul Flicek, Heng Li, Eugene Kulesha, Stefan Gräf, Nathan Johnson, Javier Herrero, Eleni M. Tomazou et al. · 2008 · Nature Biotechnology
- Retrospective Birth Dating of Cells in HumansKirsty L. Spalding, Ratan D. Bhardwaj, Bruce A. Buchholz, Henrik Druid, Jonas Frisén · 2005 · Cell
- The transcriptional repressor JHDM3A demethylates trimethyl histone H3 lysine 9 and lysine 36Robert J. Klose, Kenichi Yamane, Yangjin Bae, Dianzheng Zhang, Hediye Erdjument‐Bromage, Paul Tempst, Jiemin Wong, Yi Zhang · 2006 · Nature
- A Six Months Exercise Intervention Influences the Genome-wide DNA Methylation Pattern in Human Adipose TissueTina Rönn, Petr Volkov, Cajsa Davegårdh, Tasnim Dayeh, Elin Hall, Anders H. Olsson, Emma Nilsson, Åsa B. Tornberg, Marloes Dekker Nitert, Karl‐Fredrik Eriksson et al. · 2013 · PLoS Genetics
- Transposable Elements, Epigenetics, and Genome EvolutionFedoroff, Nina V. · 2012 · Science
- HP1 and the dynamics of heterochromatin maintenanceMaison, Christèle, Almouzni, Geneviève · 2004 · Nature Reviews Molecular Cell Biology
- Reduced expression of Dicer associated with poor prognosis in lung cancer patientsYoko Karube, Hisaaki Tanaka, Hirotaka Osada, Shuta Tomida, Yoshio Tatematsu, Kiyoshi Yanagisawa, Yasushi Yatabe, Junichi Takamizawa, Shinichiro Miyoshi, Tetsuya Mitsudomi et al. · 2005 · Cancer Science
- The Mammalian SIR2α Protein Has a Role in Embryogenesis and GametogenesisMcBurney, Michael W., Yang, Xiaofeng, Jardine, Karen, Hixon, Mary, Boekelheide, Kim, Webb, John R., Lansdorp, Peter M., Lemieux, Madeleine · 2003 · Molecular and Cellular Biology
- PGC7/Stella protects against DNA demethylation in early embryogenesisToshinobu Nakamura, Yoshikazu Arai, Hiroki Umehara, Masaaki Masuhara, Tohru Kimura, Hisaaki Taniguchi, Toshihiro Sekimoto, Masahito Ikawa, Yoshihiro Yoneda, Masaru Okabe et al. · 2006 · Nature Cell Biology
- Cancer as a dysregulated epigenome allowing cellular growth advantage at the expense of the hostWinston Timp, Andrew P. Feinberg · 2013 · Nature reviews. Cancer
- Epigenetic Mechanisms and the Mismatch Concept of the Developmental Origins of Health and DiseaseKeith M. Godfrey, Karen A. Lillycrop, Graham C. Burdge, Peter David Gluckman, Mark A. Hanson · 2007 · Pediatric Research
- Constitutive heterochromatin formation and transcription in mammalsNehmé Saksouk, Elisabeth Simboeck, Jérôme Déjardin · 2015 · Epigenetics & Chromatin
- The Transcriptome and DNA Methylome Landscapes of Human Primordial Germ CellsFan Guo, Liying Yan, Hongshan Guo, Lin Li, Boqiang Hu, Yangyu Zhao, Jun Yong, Yuqiong Hu, Xiaoye Wang, Yuan Wei et al. · 2015 · Cell
- Quantitative comparison of genome-wide DNA methylation mapping technologiesChristoph Bock, Eleni M. Tomazou, Arie B. Brinkman, Fabian Müller, Femke Simmer, Hongcang Gu, Natalie Jäger, Andreas Gnirke, Hendrik G. Stunnenberg, Alexander Meissner · 2010 · Nature Biotechnology
- Analysing and interpreting DNA methylation dataChristoph Bock · 2012 · Nature Reviews Genetics
- A Bayesian hierarchical model to detect differentially methylated loci from single nucleotide resolution sequencing dataHao Feng, Karen N. Conneely, Hao Wu · 2014 · Nucleic Acids Research
- The alternative role of DNA methylation in splicing regulationGalit Lev-Maor, Ahuvi Yearim, Gil Ast · 2015 · Trends in Genetics
- Epigenetic mechanisms in neurological diseases: genes, syndromes, and therapiesRocío G. Urdinguio, Jose Vicente Sanchez-Mut, Manel Esteller · 2009 · The Lancet Neurology
- Nuclear reprogramming of cloned embryos and its implications for therapeutic cloningXiangzhong Yang, Sadie L. Marjani, Xiuchun Tian, Harris A. Lewin, Jean Paul J. P. Renard, Teruhiko Wakayama · 2007 · Nature Genetics
- The Dnmt1 DNA-(cytosine-C5)-methyltransferase Methylates DNA Processively with High Preference for Hemimethylated Target SitesAndrea Hermann, Rachna Goyal, Albert Jeltsch · 2004 · Journal of Biological Chemistry
- Role of the Dnmt3 family in de novo methylation of imprinted and repetitive sequences during male germ cell development in the mouseYuzuru Kato, Masahiro Kaneda, Kenichiro Hata, Kenji Kumaki, Mizue Hisano, Yuji Kohara, Masaki Okano, En Li, Masami Nozaki, Hiroyuki Sasaki · 2007 · Human Molecular Genetics
- Induction of altered epigenetic regulation of the hepatic glucocorticoid receptor in the offspring of rats fed a protein-restricted diet during pregnancy suggests that reduced DNA methyltransferase-1 expression is involved in impaired DNA methylation and changes in histone modificationsKaren A. Lillycrop, Joanne L. Slater-Jefferies, Mark A. Hanson, Keith M. Godfrey, Alan A. Jackson, Graham C. Burdge · 2007 · British Journal Of Nutrition
- Global Epigenetic and Transcriptional Trends among Two Rice Subspecies and Their Reciprocal HybridsGuangming He, Xiaopeng Zhu, Axel A. Elling, Liangbi Chen, Xiangfeng Wang, Lan Ping Guo, Manzhong Liang, Hang He, Huiyong Zhang, Fangfang Chen et al. · 2010 · The Plant Cell
- Epigenetics and the environmental regulation of the genome and its functionZhang, Tie-Yuan, Meaney, Michael J. · 2010 · Annual Review of Psychology
- Epigenetic Reactivation of Tumor Suppressor Genes by a Novel Small-Molecule Inhibitor of Human DNA MethyltransferasesBodo Brueckner, Regine Garcia Boy, Pawel S. Siedlecki, Tanja Musch, Hans‐Christian Kliem, Piotr Zielenkiewicz, Sándor Suhai, Manfred Wießler, Frank Lyko · 2005 · Cancer Research
- Extensive and orderly reprogramming of genome-wide chromatin modifications associated with specification and early development of germ cells in miceYoshiyuki Seki, Katsuhiko Hayashi, Kunihiko Itoh, Michinao Mizugaki, Mitinori Saitou, Yasuhisa Matsui · 2004 · Developmental Biology
- Maintenance of self‐renewal ability of mouse embryonic stem cells in the absence of DNA methyltransferases Dnmt1, Dnmt3a and Dnmt3bAkiko Tsumura, Tomohiro Hayakawa, Yuichi Kumaki, Shin‐ichiro Takebayashi, Morito Sakaue, Chisa Matsuoka, Kunitada Shimotohno, Fuyuki Ishikawa, En Li, Hiroki R. Ueda et al. · 2006 · Genes to Cells
- Mitogen-Activated Protein (MAP) Kinase/MAP Kinase Phosphatase Regulation: Roles in Cell Growth, Death, and CancerTarek Boutros, Éric Chevet, Peter P. Metrakos · 2008 · Pharmacological Reviews
- What do you mean, “epigeneticDeans, Carrie, Maggert, Keith A · 2015 · Genetics
- Biochemistry and biology of mammalian DNA methyltransferasesA. Hermann, Humaira Gowher, Albert Jeltsch · 2004 · Cellular and Molecular Life Sciences
- Mapping Human EpigenomesRivera, Chloe M., Ren, Bing · 2013 · Cell
- DNMT3L Stimulates the DNA Methylation Activity of Dnmt3a and Dnmt3b through a Direct InteractionIsao Suetake, Fuminori Shinozaki, Junichi Miyagawa, Hideyuki Takeshima, Shoji Tajima · 2004 · Journal of Biological Chemistry
- Signaling pathways involved in colorectal cancer: pathogenesis and targeted therapyLi, Qing, Geng, Shan, Luo, Hao, Wang, Wei, Mo, Ya-Qi, Luo, Qing, Wang, Lu, Song, Guan-Bin, Sheng, Jian-Peng, Xu, Bo · 2024 · Signal Transduction and Targeted Therapy
- Base-resolution analyses of sequence and parent-of-origin dependent DNA methylation in the mouse genomeXie, Wei, Barr, Cathy L., Kim, Audrey, Yue, Feng, Lee, Ah Young, Eubanks, James, Dempster, Emma L., Ren, Bing · 2012 · Cell
- Maternal obesity and fetal metabolic programming: a fertile epigenetic soilMargaret J. R. Heerwagen, Melissa R. Miller, Linda A. Barbour, Jacob E. Friedman · 2010 · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology
- The multi-factorial nature of clinical multidrug resistance in cancerYehuda G. Assaraf, Anamaria Brozović, Ana Cristina Gonçalves, Dana Jurkovičová, Aija Linē, Miguel Machuqueiro, Simona Saponara, Ana Bela Sarmento‐Ribeiro, Cristina P. R. Xavier, M. Helena Vasconcelos · 2019 · Drug Resistance Updates
- Functions and mechanisms of epigenetic inheritance in animalsKsenia Skvortsova, Nicola Iovino, Ozren Bogdanović · 2018 · Nature Reviews Molecular Cell Biology
- Enzymatic methyl sequencing detects DNA methylation at single-base resolution from picograms of DNARomualdas Vaisvila, V. K. Chaithanya Ponnaluri, Zhiyi Sun, Bradley W. Langhorst, Lana Saleh, Shengxi Guan, Nan Dai, Matthew A. Campbell, Brittany S. Sexton, Katherine Marks et al. · 2021 · Genome Research
- Differential methylation analysis for BS-seq data under general experimental designYongseok Park, Hao Wu · 2016 · Bioinformatics
- Epigenetic Marking Correlates with Developmental Potential in Cloned Bovine Preimplantation EmbryosFátima Santos, Valeri Zakhartchenko, Miodrag Stojković, Antoine H.F.M. Peters, Thomas Jenuwein, Eckhard Wolf, Wolf Reik, Wendy Dean · 2003 · Current Biology
- DNMT3A in haematological malignanciesLiubin Yang, Rachel E. Rau, Margaret A. Goodell · 2015 · Nature reviews. Cancer
- Single-cell methylome landscapes of mouse embryonic stem cells and early embryos analyzed using reduced representation bisulfite sequencingGuo, Hongshan, Zhu, Ping, Wu, Xinglong, Li, Xianlong, Wen, Lu, Tang, Fuchou · 2013 · Genome Research
- Mammalian genomic imprintingBartolomei, M. S., Ferguson-Smith, A. C. · 2011 · Cold Spring Harbor Perspectives in Biology
- Epigenetic mechanisms in mammalsJ. K. Kim, Mala Samaranayake, Sriharsa Pradhan · 2008 · Cellular and Molecular Life Sciences
- DNA Methyltransferase Inhibitors and the Development of Epigenetic Cancer TherapiesFrank Lyko, Robert Eldon Brown · 2005 · JNCI Journal of the National Cancer Institute
- Epigenetic mechanisms in cognitionDay, Jeremy J., Sweatt, J. David · 2011 · Neuron
- Cancer chemoprevention by dietary polyphenols: Promising role for epigeneticsAlexander Link, Francesc Balaguer, Ajay Goel · 2010 · Biochemical Pharmacology
- Sex Determination in the HymenopteraGeorge E. Heimpel, Jetske G. de Boer · 2007 · Annual Review of Entomology
- Mapping DNA methylation with high-throughput nanopore sequencingRand, Arthur C, Jain, Miten, Eizenga, Jordan M, Musselman-Brown, Audrey, Olsen, Hugh E, Akeson, Mark, Paten, Benedict · 2017 · Nature Methods
- Targeted DNA demethylation and activation of endogenous genes using programmable TALE-TET1 fusion proteinsMorgan L. Maeder, James F. Angstman, Marcy E. Richardson, Samantha J Linder, Vincent M Cascio, Shengdar Q. Tsai, Quan Van Ho, Jeffry D. Sander, Deepak Reyon, B Bernstein et al. · 2013 · Nature Biotechnology
- DNA methylation and methyl-CpG binding proteins: developmental requirements and functionOzren Bogdanović, Gert Jan C. Veenstra · 2009 · Chromosoma
- Environmental chemical exposures and human epigeneticsLifang Hou, Xiao Zhang, Dong Wang, Andrea Baccarelli · 2011 · International Journal of Epidemiology
- KDM2B links the Polycomb Repressive Complex 1 (PRC1) to recognition of CpG islandsAnca M. Farcas, Neil P. Blackledge, Ian M. Sudbery, Hannah K. Long, Joanna F. McGouran, Nathan R. Rose, Sheena Lee, David Sims, Andrea Cerase, Thomas W. Sheahan et al. · 2012 · eLife
- RETRACTED: Methyl-CpG Binding Protein MBD1 Couples Histone H3 Methylation at Lysine 9 by SETDB1 to DNA Replication and Chromatin AssemblyShireen A. Sarraf, Irina Stancheva · 2004 · Molecular Cell · Retracted
- Transgenerational response to nutrition, early life circumstances and longevityKaati, Gunnar, Bygren, Lars Olov, Pembrey, Marcus, Sjöström, Michael · 2007 · European Journal of Human Genetics
- DNA Methylation Analysis by PyrosequencingFlorence Busato, Jörg Tost · 2014 · Springer eBooks
- Position-Effect Variegation, Heterochromatin Formation, and Gene Silencing in DrosophilaElgin, S. C. R., Reuter, G. · 2013 · Cold Spring Harbor Perspectives in Biology
- Widespread contribution of transposable elements to the innovation of gene regulatory networksVasavi Sundaram, Yong Cheng, Zhihai Ma, Daofeng Li, Xiaoyun Xing, Peter Edge, Michael P. Snyder, Ting Wang · 2014 · Genome Research
- Genome-wide Analysis Reveals TET- and TDG-Dependent 5-Methylcytosine Oxidation DynamicsShen, Li, Wu, Hao, Diep, Dinh, Yamaguchi, Shinpei, D’Alessio, Ana C., Fung, Ho-Lim, Zhang, Kun, Zhang, Yi · 2013 · Cell
- Targeted disruption of DNMT1, DNMT3A and DNMT3B in human embryonic stem cellsJing Liao, Rahul Karnik, Hongcang Gu, Michael J. Ziller, Kendell Clement, Alexander M. Tsankov, Veronika Akopian, Casey A. Gifford, Julie Donaghey, Christina Galonska et al. · 2015 · Nature Genetics
- Growth and the regulation of myotomal muscle mass in teleost fishJohnston, Ian A., Bower, Neil I., Macqueen, Daniel J. · 2011 · Journal of Experimental Biology
- Cross talk between microRNA and epigenetic regulation in adult neurogenesisSzulwach, Keith E., Li, Xuekun, Smrt, Richard D., Li, Yujing, Luo, Yuping, Lin, Li, Santistevan, Nicholas J., Li, Wendi, Zhao, Xinyu, Jin, Peng · 2010 · Journal of Cell Biology
- Epigenetics and cancerLund, Anders H., van Lohuizen, Maarten · 2004 · Genes & Development
- Spatial heterogeneity in the mammalian liverBen-Moshe, Shani, Itzkovitz, Shalev · 2019 · Nature Reviews Gastroenterology & Hepatology
- Detection and interpretation of altered methylation patterns in cancer cellsUshijima, Toshikazu · 2005 · Nature Reviews Cancer
- Asymmetric regulation of imprinting on the maternal and paternal chromosomes at the Dlk1-Gtl2 imprinted cluster on mouse chromosome 12Shau‐Ping Lin, Neil A. Youngson, Shuji Takada, Hervé Seitz, Wolf Reik, Martina Paulsen, Jérôme Cavaillé, Anne C. Ferguson‐Smith · 2003 · Nature Genetics
- Interplay between Two Epigenetic MarksLianna M. Johnson, Xiaofeng Cao, Steven E. Jacobsen · 2002 · Current Biology
- Combined DNA Methyltransferase and Histone Deacetylase Inhibition in the Treatment of Myeloid NeoplasmsSteven D. Gore, Stephen B. Baylin, Elizabeth A. Sugar, Hetty E. Carraway, Carole Brennan Miller, Michael Anthony Carducci, Michael R. Grever, Oliver Galm, Tianna Dauses, Judith E. Karp et al. · 2006 · Cancer Research
- Epigenetic memory at embryonic enhancers identified in DNA methylation maps from adult mouse tissuesGary C. Hon, Nisha Rajagopal, Yin Shen, David F. McCleary, Feng Yue, My D Dang, Bing Ren · 2013 · Nature Genetics
- Cellular dynamics associated with the genome-wide epigenetic reprogramming in migrating primordial germ cells in miceYoshiyuki Seki, Masashi Yamaji, Yukihiro Yabuta, Mitsue Sano, Mayo Shigeta, Yasuhisa Matsui, Yumiko Saga, Makoto Tachibana, Yoichi Shinkai, Mitinori Saitou · 2007 · Development
- RNA Silencing: The Genome's Immune SystemRonald H.A. Plasterk · 2002 · Science
- DNA methylation and chromatin – unraveling the tangled webRobertson, Keith D · 2002 · Oncogene
- Myc represses transcription through recruitment of DNA methyltransferase corepressorCarmen Brenner, Rachel Deplus, Céline Mirjolet, Axelle E. Loriot, Emmanuelle A. Viré, Charles De Smet, Arantxa Gutiérrez, Davide Danovi, David Bernard, Thierry Boon et al. · 2004 · The EMBO Journal
- Crystal Structure of TET2-DNA Complex: Insight into TET-Mediated 5mC OxidationLulu Hu, Ze Li, Jingdong Cheng, Qinhui Rao, Wei Gong, Mengjie Liu, Yujiang Geno Shi, Jiayu Zhu, Ping Wang, Yanhui Xu · 2013 · Cell
- Feeding pregnant rats a protein-restricted diet persistently alters the methylation of specific cytosines in the hepatic PPARα promoter of the offspringKaren A. Lillycrop, Emma S. Phillips, Christopher Torrens, Mark A. Hanson, Alan A. Jackson, Graham C. Burdge · 2008 · British Journal Of Nutrition
- Targeting DNA MethylationJean‐Pierre J. Issa, Hagop M. Kantarjian · 2009 · Clinical Cancer Research
- Hypomethylation of MB-COMT promoter is a major risk factor for schizophrenia and bipolar disorderAbdolmaleky, Hamid Mostafavi, Cheng, Kuang-hung, Faraone, Stephen V., Wilcox, Marsha, Glatt, Stephen J., Gao, Fangming, Smith, Cassandra L., Shafa, Rahim, Aeali, Batol, Carnevale, Julie et al. · 2006 · Human Molecular Genetics
- DNA methylation and breast carcinogenesisMartin Widschwendter, Peter A. Jones · 2002 · Oncogene
- Selective, stable demethylation of the interleukin-2 gene enhances transcription by an active processDenis Bruniquel, Ronald H. Schwartz · 2003 · Nature Immunology
- Circular RNAs in Cancer: emerging functions in hallmarks, stemness, resistance and roles as potential biomarkersMin Su, Yuhang Xiao, Junliang Ma, Yanyan Tang, Bo Tian, Yu‐Qin Zhang, Li Xu, Zhining Wu, Desong Yang, Yong Zhou et al. · 2019 · Molecular Cancer
- Computational analysis of core promoters in the Drosophila genomeUwe Ohler, Guochun Liao, Heinrich Niemann, Gerald M. Rubin · 2002 · Genome biology
- Promoter CpG Methylation Contributes to ES Cell Gene Regulation in Parallel with Oct4/Nanog, PcG Complex, and Histone H3 K4/K27 TrimethylationShaun D. Fouse, Yin Shen, Matteo A. Pellegrini, Steve W. Cole, Alexander Meissner, Leander Van Neste, Rudolf Jaenisch, Guoping Fan · 2008 · Cell stem cell
- The many faces of REST oversee epigenetic programming of neuronal genesNurit Ballas, Gail Mandel · 2005 · Current Opinion in Neurobiology
- DNA methylation: An epigenetic mark of cellular memoryKim, Mirang, Costello, Joseph · 2017 · Experimental & Molecular Medicine
- MECP2 is progressively expressed in post-migratory neurons and is involved in neuronal maturation rather than cell fate decisionsKishi, Noriyuki, Macklis, Jeffrey D. · 2004 · Molecular and Cellular Neuroscience
- DNA methylome profiling of human tissues identifies global and tissue-specific methylation patternsLokk, Kaie, Modhukur, Vijayachitra, Rajashekar, Balaji, Märtens, Kaspar, Mägi, Reedik, Kolde, Raivo, Koltšina, Marina, Nilsson, Torbjörn K, Vilo, Jaak, Salumets, Andres et al. · 2014 · Genome Biology
- Errors in development of fetuses and placentas from in vitro-produced bovine embryosPeter W. Farin, Jorge A. Piedrahita, Charlotte E. Farin · 2005 · Theriogenology
- RETRACTED ARTICLE: 5-Aza-Deoxycytidine Induces Selective Degradation of DNA Methyltransferase 1 by a Proteasomal Pathway That Requires the KEN Box, Bromo-Adjacent Homology Domain, and Nuclear Localization SignalKalpana Ghoshal, Jharna Datta, Sarmila Majumder, Shoumei Bai, Huban Kutay, Tasneem Motiwala, Samson T. Jacob · 2005 · Molecular and Cellular Biology · Retracted
- Passive and active DNA methylation and the interplay with genetic variation in gene regulationGutierrez-Arcelus, Maria, Lappalainen, Tuuli, Montgomery, Stephen B, Buil, Alfonso, Ongen, Halit, Yurovsky, Alisa, Bryois, Julien, Giger, Thomas, Romano, Luciana, Planchon, Alexandra et al. · 2013 · eLife
- G9a/GLP complexes independently mediate H3K9 and DNA methylation to silence transcriptionMakoto Tachibana, Yasuko Matsumura, Mikiko Fukuda, Hiroshi Kimura, Yoichi Shinkai · 2008 · The EMBO Journal