The touchscreen cognitive testing method for rodents: How to get the best out of your rat

Cambridge Neuropsychological Test Automated Battery (CANTAB): A Factor Analytic Study of a Large Sample of Normal Elderly Volunteers

Robbins, T. W., James, M., Owen, A. M., Sahakian, B. J., McInnes, L., & Rabbitt, P. (1994) · Dementia and Geriatric Cognitive Disorders · doi:10.1159/000106735 · Cited by 1,078

Dissociation in Effects of Lesions of the Nucleus Accumbens Core and Shell on Appetitive Pavlovian Approach Behavior and the Potentiation of Conditioned Reinforcement and Locomotor Activity byd-Amphetamine

Parkinson, J. A., Olmstead, M. C., Burns, L. H., Robbins, T. W., & Everitt, B. J. (1999) · The Journal of Neuroscience · doi:10.1523/jneurosci.19-06-02401.1999 · Cited by 555

Dissociable Contributions of the Orbitofrontal and Infralimbic Cortex to Pavlovian Autoshaping and Discrimination Reversal Learning: Further Evidence for the Functional Heterogeneity of the Rodent Frontal Cortex

Chudasama, Y., & Robbins, T. W. (2003) · The Journal of Neuroscience · doi:10.1523/jneurosci.23-25-08771.2003 · Cited by 543

Variation in visual acuity within pigmented, and between pigmented and albino rat strains

Prusky, G. T., Harker, K. T., Douglas, R. M., & Whishaw, I. Q. (2002) · Behavioural Brain Research · doi:10.1016/s0166-4328(02)00126-2 · Cited by 321

Triple dissociation of anterior cingulate, posterior cingulate, and medial frontal cortices on visual discrimination tasks using a touchscreen testing procedure for the rat.

Bussey, T. J., Muir, J. L., Everitt, B. J., & Robbins, T. W. (1997) · Behavioral Neuroscience · doi:10.1037//0735-7044.111.5.920 · Cited by 311

Nucleus accumbens dopamine depletion impairs both acquisition and performance of appetitive Pavlovian approach behaviour: implications for mesoaccumbens dopamine function

Parkinson, J. A., Dalley, J. W., Cardinal, R. N., Bamford, A., Fehnert, B., Lachenal, G., Rudarakanchana, N., Halkerston, K. M., Robbins, T. W., & Everitt, B. J. (2002) · Behavioural Brain Research · doi:10.1016/s0166-4328(02)00291-7 · Cited by 288

Impairments in visual discrimination after perirhinal cortex lesions: testing ‘declarative’ vs. ‘perceptual‐mnemonic’ views of perirhinal cortex function

Bussey, T. J., Saksida, L. M., & Murray, E. A. (2003) · European Journal of Neuroscience · doi:10.1046/j.1460-9568.2003.02475.x · Cited by 221

Time-limited modulation of appetitive Pavlovian memory by D1 and NMDA receptors in the nucleus accumbens

Dalley, J. W., Lääne, K., Theobald, D. E. H., Armstrong, H. C., Corlett, P. R., Chudasama, Y., & Robbins, T. W. (2005) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0502080102 · Cited by 214

Dissociable effects of cingulate and medial frontal cortex lesions on stimulus-reward learning using a novel Pavlovian autoshaping procedure for the rat: Implications for the neurobiology of emotion.

Bussey, T. J., Everitt, B. J., & Robbins, T. W. (1997) · Behavioral Neuroscience · doi:10.1037//0735-7044.111.5.908 · Cited by 210

Behavioral phenotypes of amyloid‐based genetically modified mouse models of Alzheimer's disease

Kobayashi, D. T., & Chen, K. S. (2005) · Genes Brain & Behavior · doi:10.1111/j.1601-183x.2005.00124.x · Cited by 182

The touchscreen operant platform for testing learning and memory in rats and mice

Horner, A. E., Heath, C. J., Hvoslef‐Eide, M., Kent, B. A., Kim, C. H., Nilsson, S. R. O., Alsiö, J., Oomen, C. A., Holmes, A., Saksida, L. M., et al. (2013) · Nature Protocols · doi:10.1038/nprot.2013.122 · Cited by 412

Drug development for neurodevelopmental disorders: lessons learned from fragile X syndrome

Berry-Kravis, E. M., Lindemann, L., Jønch, A. E., Apostol, G., Bear, M. F., Carpenter, R. L., Crawley, J. N., Curie, A., Des Portes, V., Hossain, F., et al. (2018) · Nature Reviews Drug Discovery · doi:10.1038/nrd.2017.221 · Cited by 336

New translational assays for preclinical modelling of cognition in schizophrenia: The touchscreen testing method for mice and rats

Bussey, T. J., Holmes, A., Lyon, L., Mar, A. C., McAllister, K. A. L., Nithianantharajah, J., Oomen, C. A., & Saksida, L. M. (2012) · Neuropharmacology · doi:10.1016/j.neuropharm.2011.04.011 · Cited by 299

The touchscreen operant platform for assessing executive function in rats and mice

Mar, A. C., Horner, A. E., Nilsson, S. R. O., Alsiö, J., Kent, B. A., Kim, C. H., Holmes, A., Saksida, L. M., & Bussey, T. J. (2013) · Nature Protocols · doi:10.1038/nprot.2013.123 · Cited by 271

Figure-ground perception in the awake mouse and neuronal activity elicited by figure-ground stimuli in primary visual cortex

Schnabel, U. H., Bossens, C., Lorteije, J. A. M., Self, M. W., de Beeck, H. O., & Roelfsema, P. R. (2018) · Scientific Reports · doi:10.1038/s41598-018-36087-8 · Cited by 227

The touchscreen operant platform for testing working memory and pattern separation in rats and mice.

Oomen, C. A., Hvoslef-Eide, M., Heath, C. J., Mar, A. C., Horner, A. E., Bussey, T. J., & Saksida, L. M. (2013) · Nature Protocols · doi:10.1038/nprot.2013.124 · Cited by 193

A rodent model for the study of invariant visual object recognition

Zoccolan, D., Oertelt, N., DiCarlo, J. J., & Cox, D. (2009) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0811583106 · Cited by 167

Selective Activation of M4 Muscarinic Acetylcholine Receptors Reverses MK-801-Induced Behavioral Impairments and Enhances Associative Learning in Rodents

Bubser, M., Bridges, T. M., Dencker, D., Gould, R. W., Grannan, M. D., Noetzel, M. J., Lamsal, A., Niswender, C. M., Daniels, J. S., Poslusney, M. S., et al. (2014) · ACS Chemical Neuroscience · doi:10.1021/cn500128b · Cited by 155

Whisker: A client—server high-performance multimedia research control system

Cardinal, R. N., & Aitken, M. R. F. (2010) · Behavior Research Methods · doi:10.3758/brm.42.4.1059 · Cited by 143

Transiently lowering tumor necrosis factor-α synthesis ameliorates neuronal cell loss and cognitive impairments induced by minimal traumatic brain injury in mice

Baratz-Goldstein, R., Tweedie, D., Wang, J., Rubovitch, V., Luo, W., Hoffer, B. J., Greig, N. H., & Pick, C. G. (2015) · Journal of Neuroinflammation · doi:10.1186/s12974-015-0237-4 · Cited by 136

The BTBR Mouse Model of Autism Spectrum Disorders Has Learning and Attentional Impairments and Alterations in Acetylcholine and Kynurenic Acid in Prefrontal Cortex

McTighe, S. M., Webb, S. J. N., Lin, Q., Hughes, Z. A., & Smith, D. G. (2013) · PLoS ONE · doi:10.1371/journal.pone.0062189 · Cited by 139

The NIH Toolbox Cognitive Battery for intellectual disabilities: Three preliminary studies and future directions

Hessl, D., Sansone, S. M., Berry-Kravis, E., Riley, K., Widaman, K. F., Abbeduto, L., Schneider, A., Coleman, J., Oaklander, D., Rhodes, K. C., et al. (2016) · Journal of Neurodevelopmental Disorders · doi:10.1186/s11689-016-9167-4 · Cited by 126

The rat perirhinal cortex: A review of anatomy, physiology, plasticity, and function

Kealy, J., & Commins, S. (2011) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2011.03.002 · Cited by 123

Trial-unique, delayed nonmatching-to-location (TUNL): A novel, highly hippocampus-dependent automated touchscreen test of location memory and pattern separation

Talpos, J. C., McTighe, S. M., Dias, R. S., Saksida, L. M., & Bussey, T. J. (2010) · Neurobiology of Learning and Memory · doi:10.1016/j.nlm.2010.07.006 · Cited by 131

Animal models of working memory: A review of tasks that might be used in screening drug treatments for the memory impairments found in schizophrenia

Dudchenko, P. A., Talpos, J. C., Young, J. W., & Baxter, M. G. (2012) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2012.03.003 · Cited by 123

A novel touchscreen-automated paired-associate learning (PAL) task sensitive to pharmacological manipulation of the hippocampus: a translational rodent model of cognitive impairments in neurodegenerative disease

Talpos, J. C., Winters, B. D., Dias, R. S., Saksida, L. M., & Bussey, T. J. (2009) · Psychopharmacology · doi:10.1007/s00213-009-1526-3 · Cited by 122

Bridging the translational divide: identical cognitive touchscreen testing in mice and humans carrying mutations in a disease-relevant homologous gene

Nithianantharajah, J., McKechanie, A. G., Stewart, T., Johnstone, M., Blackwood, D., Clair, D. S., Grant, S. G. N., Bussey, T. J., & Saksida, L. M. (2015) · Scientific Reports · doi:10.1038/srep14613 · Cited by 121

A touch screen-automated cognitive test battery reveals impaired attention, memory abnormalities, and increased response inhibition in the TgCRND8 mouse model of Alzheimer's disease

Romberg, C., Horner, A. E., Bussey, T. J., & Saksida, L. M. (2012) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2012.08.006 · Cited by 111

A new touchscreen test of pattern separation: effect of hippocampal lesions

McTighe, S. M., Mar, A. C., Romberg, C., Bussey, T. J., & Saksida, L. M. (2009) · Neuroreport · doi:10.1097/wnr.0b013e32832c5eb2 · Cited by 106

Inhibitory Control Deficits in Rats with Ventral Hippocampal Lesions

Abela, A. R., Dougherty, S. D., Fagen, E. D., Hill, C. J. R., & Chudasama, Y. (2012) · Cerebral Cortex · doi:10.1093/cercor/bhs121 · Cited by 104

The surveillance state of behavioral automation

Schaefer, A. T., & Claridge‐Chang, A. (2011) · Current Opinion in Neurobiology · doi:10.1016/j.conb.2011.11.004 · Cited by 90

Invariant visual object recognition and shape processing in rats

Zoccolan, D. (2015) · Behavioural Brain Research · doi:10.1016/j.bbr.2014.12.053 · Cited by 91

Class I histone deacetylase inhibition ameliorates social cognition and cell adhesion molecule plasticity deficits in a rodent model of autism spectrum disorder

Foley, A., Gannon, S. P., Rombach, N., Prendergast, A., Barry, C. E., Cassidy, A. W., & Regan, C. M. (2012) · Neuropharmacology · doi:10.1016/j.neuropharm.2012.05.042 · Cited by 86

Taking personality selection bias seriously in animal cognition research: a case study in capuchin monkeys (Sapajus apella)

Morton, F. B., Lee, P. C., & Buchanan‐Smith, H. M. (2013) · Animal Cognition · doi:10.1007/s10071-013-0603-5 · Cited by 84

Touchscreen technology in the study of cognition-related behavior

Kangas, B. D., & Bergman, J. (2017) · Behavioural Pharmacology · doi:10.1097/fbp.0000000000000356 · Cited by 78

A review of zoo‐based cognitive research using touchscreen interfaces

Egelkamp, C. L., & Ross, S. R. (2018) · Zoo Biology · doi:10.1002/zoo.21458 · Cited by 81

Touchscreen-Based Cognitive Tasks Reveal Age-Related Impairment in a Primate Aging Model, the Grey Mouse Lemur (Microcebus murinus)

Joly, M., Ammersdörfer, S., Schmidtke, D., & Zimmermann, E. (2014) · PLoS ONE · doi:10.1371/journal.pone.0109393 · Cited by 78

Inflammatory profiles in the BTBR mouse: how relevant are they to autism spectrum disorders?

Careaga, M., Schwartzer, J., & Ashwood, P. (2015) · Brain Behavior and Immunity · doi:10.1016/j.bbi.2014.06.006 · Cited by 77

Maladaptive cortical hyperactivity upon recovery from experimental autoimmune encephalomyelitis

Ellwardt, E., Pramanik, G. K., Luchtman, D. W., Novkovic, T., Jubal, E. R., Vogt, J., Arnoux, I., Vogelaar, C. F., Mandal, S., Schmalz, M., et al. (2018) · Nature Neuroscience · doi:10.1038/s41593-018-0193-2 · Cited by 77

α7 nicotinic acetylcholine receptors in the hippocampal circuit: taming complexity

Letsinger, A. C., Gu, Z., & Yakel, J. L. (2022) · Trends in Neurosciences · doi:10.1016/j.tins.2021.11.006 · Cited by 74

Touchscreen learning deficits and normal social approach behavior in the Shank3B model of Phelan–McDermid Syndrome and autism

Copping, N. A., Berg, E. L., Foley, G. M., Schaffler, M. D., Onaga, B., Buscher, N., Silverman, J. L., & Yang, M. (2016) · Neuroscience · doi:10.1016/j.neuroscience.2016.05.016 · Cited by 75

Intact attentional processing but abnormal responding in M1 muscarinic receptor-deficient mice using an automated touchscreen method

Bartko, S. J., Romberg, C., White, B., Wess, J., Bussey, T. J., & Saksida, L. M. (2011) · Neuropharmacology · doi:10.1016/j.neuropharm.2011.08.023 · Cited by 71

16p11.2 deletion mice display cognitive deficits in touchscreen learning and novelty recognition tasks

Yang, M., Lewis, F. C., Sarvi, M. S., Foley, G. M., & Crawley, J. N. (2015) · Learning & Memory · doi:10.1101/lm.039602.115 · Cited by 70

A review of the 5-Choice Serial Reaction Time (5-CSRT) task in different vertebrate models

Fizet, J., Cassel, J., Kelche, C. R., & Meunier, H. (2016) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2016.08.027 · Cited by 69

Aging effects on discrimination learning, logical reasoning and memory in pet dogs

Wallis, L., Virányi, Z., Müller, C. A., Serisier, S., Huber, L., & Range, F. (2016) · AGE · doi:10.1007/s11357-015-9866-x · Cited by 67

A computer-automated touchscreen paired-associates learning (PAL) task for mice: impairments following administration of scopolamine or dicyclomine and improvements following donepezil

Bartko, S. J., Vendrell, I., Saksida, L. M., & Bussey, T. J. (2010) · Psychopharmacology · doi:10.1007/s00213-010-2050-1 · Cited by 69

Vision in laboratory rodents—Tools to measure it and implications for behavioral research

Leinonen, H., & Tanila, H. (2017) · Behavioural Brain Research · doi:10.1016/j.bbr.2017.07.040 · Cited by 64

Role for the M1 Muscarinic Acetylcholine Receptor in Top-Down Cognitive Processing Using a Touchscreen Visual Discrimination Task in Mice

Gould, R. W., Dencker, D., Grannan, M. D., Bubser, M., Zhan, X., Wess, J., Xiang, Z., Locuson, C. W., Lindsley, C. W., Conn, P. J., et al. (2015) · ACS Chemical Neuroscience · doi:10.1021/acschemneuro.5b00123 · Cited by 60

Environmental enrichment enhances cognitive flexibility in C57BL/6 mice on a touchscreen reversal learning task

Zeleznikow-Johnston, A., Burrows, E. L., Renoir, T., & Hannan, A. J. (2017) · Neuropharmacology · doi:10.1016/j.neuropharm.2017.02.009 · Cited by 60

The NEWMEDS rodent touchscreen test battery for cognition relevant to schizophrenia

Hvoslef‐Eide, M., Mar, A. C., Nilsson, S. R. O., Alsiö, J., Heath, C. J., Saksida, L. M., Robbins, T. W., & Bussey, T. J. (2015) · Psychopharmacology · doi:10.1007/s00213-015-4007-x · Cited by 61

The role of the dorsal hippocampus in two versions of the touchscreen automated paired associates learning (PAL) task for mice

Kim, C. H., Heath, C. J., Kent, B. A., Bussey, T. J., & Saksida, L. M. (2015) · Psychopharmacology · doi:10.1007/s00213-015-3949-3 · Cited by 63

Collinear features impair visual detection by rats

Meier, P., Flister, E., & Reinagel, P. (2011) · Journal of Vision · doi:10.1167/11.3.22 · Cited by 57

Impact of spaceflight stressors on behavior and cognition: A molecular, neurochemical, and neurobiological perspective

Desai, R. I., Limoli, C. L., Stark, C. E. L., & Stark, S. M. (2022) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2022.104676 · Cited by 55

The role of 5-HT2C receptors in touchscreen visual reversal learning in the rat: a cross-site study

Alsiö, J., Nilsson, S. R. O., Gastambide, F., Wang, R. A. H., Dam, S. A., Mar, A. C., Tricklebank, M., & Robbins, T. W. (2015) · Psychopharmacology · doi:10.1007/s00213-015-3963-5 · Cited by 53

Predictably irrational: assaying cognitive inflexibility in mouse models of schizophrenia

Brigman, J. L. (2010) · Frontiers in Neuroscience · doi:10.3389/neuro.01.013.2010 · Cited by 52

Touchscreen cognitive testing: Cross-species translation and co-clinical trials in neurodegenerative and neuropsychiatric disease

Palmer, D. D., Dumont, J. R., Dexter, T. D., Prado, M. A. M., Finger, E. C., Bussey, T. J., & Saksida, L. M. (2021) · Neurobiology of Learning and Memory · doi:10.1016/j.nlm.2021.107443 · Cited by 54

Strain-dependent effects on acquisition and reversal of visual and spatial tasks in a rat touchscreen battery of cognition

Kumar, G., Talpos, J., & Steckler, T. (2015) · Physiology & Behavior · doi:10.1016/j.physbeh.2015.03.001 · Cited by 51

MK-801 and cognitive functions: Investigating the behavioral effects of a non-competitive NMDA receptor antagonist

Janus, A., Lustyk, K., & Pytka, K. (2023) · Psychopharmacology · doi:10.1007/s00213-023-06454-z · Cited by 50

Paying more attention to attention: Towards more comprehensive cognitive translation using mouse models of Alzheimer's disease

Romberg, C., Bussey, T. J., & Saksida, L. M. (2012) · Brain Research Bulletin · doi:10.1016/j.brainresbull.2012.02.007 · Cited by 49

Cognitive Abilities on Transitive Inference Using a Novel Touchscreen Technology for Mice

Silverman, J. L., Gastrell, P. T., Karras, M. N., Solomon, M., & Crawley, J. N. (2013) · Cerebral Cortex · doi:10.1093/cercor/bht293 · Cited by 51

Rodent age‐related impairments in discriminating perceptually similar objects parallel those observed in humans

Johnson, S. A., Turner, S. M., Santacroce, L. A., Carty, K. N., Shafiq, L., Bizon, J. L., Maurer, A. P., & Burke, S. N. (2017) · Hippocampus · doi:10.1002/hipo.22729 · Cited by 49

Multi-domain cognitive assessment of male mice shows space radiation is not harmful to high-level cognition and actually improves pattern separation

Whoolery, C. W., Yun, S., Reynolds, R. P., Lucero, M. J., Soler, I., Tran, F. H., Ito, N., Redfield, R. L., Richardson, D. R., Shih, H.-Y., et al. (2020) · Scientific Reports · doi:10.1038/s41598-020-59419-z · Cited by 50

Effects of Mild Perinatal Hypothyroidism on Cognitive Function of Adult Male Offspring

Amano, I., Takatsuru, Y., Khairinisa, M. A., Kokubo, M., Haijima, A., & Koibuchi, N. (2018) · Endocrinology · doi:10.1210/en.2017-03125 · Cited by 48

AutonoMouse: High throughput operant conditioning reveals progressive impairment with graded olfactory bulb lesions

Erskine, A., Bus, T., Herb, J. T., & Schaefer, A. T. (2019) · PLoS ONE · doi:10.1371/journal.pone.0211571 · Cited by 49

More than motor impairment: A spatiotemporal analysis of cognitive impairment and associated neuropathological changes following cortical photothrombotic stroke

Sanchez‐Bezanilla, S., Hood, R. J., Collins‐Praino, L. E., Turner, R. J., Walker, F. R., Nilsson, M., & Ong, L. K. (2021) · Journal of Cerebral Blood Flow & Metabolism · doi:10.1177/0271678x211005877 · Cited by 47

A touchscreen based global motion perception task for mice

Stirman, J. N., Townsend, L. B., & Smith, S. L. (2016) · Vision Research · doi:10.1016/j.visres.2016.07.006 · Cited by 53

MouseBytes, an open-access high-throughput pipeline and database for rodent touchscreen-based cognitive assessment

Beraldo, F., Palmer, D., Memar, S., Wasserman, D., Lee, W.-J. V., Liang, S., Creighton, S., Kolisnyk, B., Cowan, M. F., Mels, J., et al. (2019) · eLife · doi:10.7554/elife.49630 · Cited by 52

A touch-screen based paired-associates learning (PAL) task for the rat may provide a translatable pharmacological model of human cognitive impairment

Talpos, J. C., Aerts, N., Fellini, L., & Steckler, T. (2014) · Pharmacology Biochemistry and Behavior · doi:10.1016/j.pbb.2014.03.014 · Cited by 47

Repetitive Neonatal Erythropoietin and Melatonin Combinatorial Treatment Provides Sustained Repair of Functional Deficits in a Rat Model of Cerebral Palsy

Jantzie, L. L., Oppong, A. Y., Conteh, F. S., Yellowhair, T. R., Kim, J., Fink, G., Wolin, A., Northington, F. J., & Robinson, S. (2018) · Frontiers in Neurology · doi:10.3389/fneur.2018.00233 · Cited by 46

The subchronic phencyclidine rat model: relevance for the assessment of novel therapeutics for cognitive impairment associated with schizophrenia

Janhunen, S. K., Svärd, H., Talpos, J., Kumar, G., Steckler, T., Plath, N., Lerdrup, L., Ruby, T., Haman, M., Wyler, R., et al. (2015) · Psychopharmacology · doi:10.1007/s00213-015-3954-6 · Cited by 43

Touching on translation

Talpos, J. C., & Steckler, T. (2013) · Cell and Tissue Research · doi:10.1007/s00441-013-1694-7 · Cited by 43

Testing cognitive functions in rodent disease models: Present pitfalls and future perspectives

Tanila, H. (2017) · Behavioural Brain Research · doi:10.1016/j.bbr.2017.05.040 · Cited by 43

Aligning physiology with psychology: Translational neuroscience in neuropsychiatric drug discovery

McArthur, R. A. (2017) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2017.02.004 · Cited by 42

Audio-Visual Detection Benefits in the Rat

Kayser, S. J., & Kayser, C. (2012) · PLoS ONE · doi:10.1371/journal.pone.0045677 · Cited by 38

Picture object recognition in an American black bear (Ursus americanus)

Johnson‐Ulrich, Z., Vonk, J. M., Humbyrd, M., Crowley, M., Wojtkowski, E., Yates, F., & Allard, S. M. (2016) · Animal Cognition · doi:10.1007/s10071-016-1011-4 · Cited by 38

New frontiers in translational research: Touchscreens, open science, and the mouse translational research accelerator platform

Sullivan, J. A., Dumont, J. R., Memar, S., Skirzewski, M., Wan, J., Mofrad, M. H., Ansari, H. Z., Li, Y., Muller, L., Prado, V. F., et al. (2020) · Genes Brain & Behavior · doi:10.1111/gbb.12705 · Cited by 39

Optimisation of cognitive performance in rodent operant (touchscreen) testing: Evaluation and effects of reinforcer strength

Phillips, B. U., Heath, C. J., Ossowska, Z., Bussey, T. J., & Saksida, L. M. (2017) · Learning & Behavior · doi:10.3758/s13420-017-0260-7 · Cited by 38

GABA, glutamate, dopamine and serotonin transporters expression on memory formation and amnesia

Tellez, R., Gómez-Víquez, L., & Meneses, A. (2011) · Neurobiology of Learning and Memory · doi:10.1016/j.nlm.2011.12.002 · Cited by 37

Dystrophin induced cognitive impairment: mechanisms, models and therapeutic strategies

Anand, A., Tyagi, R., Mohanty, M., Goyal, M., de Silva, K. R. D., & Wijekoon, N. (2015) · Annals of Neurosciences · doi:10.5214/ans.0972.7531.221210 · Cited by 38

More Than Eggs – Relationship Between Productivity and Learning in Laying Hens

Dudde, A., Krause, E. T., Matthews, L. R., & Schrader, L. (2018) · Frontiers in Psychology · doi:10.3389/fpsyg.2018.02000 · Cited by 36

Performance of the intracerebroventricularly injected streptozotocin Alzheimer’s disease model in a translationally relevant, aged and experienced rat population

Gáspár, A., Hutka, B., Ernyey, A. J., Tajti, B. T., Varga, B. T., Zádori, Z., & Gyertyán, I. (2022) · Scientific Reports · doi:10.1038/s41598-022-24292-5 · Cited by 35

Alcohol, flexible behavior, and the prefrontal cortex: Functional changes underlying impaired cognitive flexibility

Nippert, K. E., Rowland, C. P., Vazey, E. M., & Moorman, D. E. (2024) · Neuropharmacology · doi:10.1016/j.neuropharm.2024.110114 · Cited by 35

Dissociable effects of NR2A and NR2B NMDA receptor antagonism on cognitive flexibility but not pattern separation

Kumar, G., Olley, J., Steckler, T., & Talpos, J. C. (2015) · Psychopharmacology · doi:10.1007/s00213-015-4008-9 · Cited by 34

Automated Home-Cage Testing as a Tool to Improve Reproducibility of Behavioral Research?

Richter, S. H. (2020) · Frontiers in Neuroscience · doi:10.3389/fnins.2020.00383 · Cited by 35

A mobile, high-throughput semi-automated system for testing cognition in large non-primate animal models of Huntington disease

McBride, S. D., Perentos, N., & Morton, A. J. (2015) · Journal of Neuroscience Methods · doi:10.1016/j.jneumeth.2015.08.025 · Cited by 33

Technology or ecology? New tools to assess cognitive judgement bias in mice

Krakenberg, V., Woigk, I., Rodríguez, L. G., Kästner, N., Kaiser, S., Sachser, N., & Richter, S. H. (2019) · Behavioural Brain Research · doi:10.1016/j.bbr.2019.01.021 · Cited by 31

Impaired Visual Search in Rats Reveals Cholinergic Contributions to Feature Binding in Visuospatial Attention

Botly, L. C. P., & Rosa, E. D. (2011) · Cerebral Cortex · doi:10.1093/cercor/bhr331 · Cited by 31

Touchscreen-based location discrimination and paired associate learning tasks detect cognitive impairment at an early stage in an App knock-in mouse model of Alzheimer’s disease

Saifullah, A. B., Komine, O., Dong, Y., Fukumoto, K., Sobue, A., Endo, F., Saito, T., Saido, T. C., Yamanaka, K., & Mizoguchi, H. (2020) · Molecular Brain · doi:10.1186/s13041-020-00690-6 · Cited by 32

Effects of stimulus salience on touchscreen serial reversal learning in a mouse model of fragile X syndrome

Dickson, P. E., Corkill, B., McKimm, E., Miller, M. M., Calton, M. A., Goldowitz, D., Blaha, C. D., & Mittleman, G. (2013) · Behavioural Brain Research · doi:10.1016/j.bbr.2013.05.060 · Cited by 30

The hippocampus is required for visually cued contextual response selection, but not for visual discrimination of contexts

Kim, S. H., Lee, J., & Lee, I. (2012) · Frontiers in Behavioral Neuroscience · doi:10.3389/fnbeh.2012.00066 · Cited by 30

Mutations in neuroligin-3 in male mice impact behavioral flexibility but not relational memory in a touchscreen test of visual transitive inference

Norris, R. H. C., Churilov, L. P., Hannan, A. J., & Nithianantharajah, J. (2019) · Molecular Autism · doi:10.1186/s13229-019-0292-2 · Cited by 30

Extended Erythropoietin Treatment Prevents Chronic Executive Functional and Microstructural Deficits Following Early Severe Traumatic Brain Injury in Rats

Robinson, S., Winer, J. L., Chan, L. A. S., Oppong, A. Y., Yellowhair, T. R., Maxwell, J. R., Andrews, N. A., Yang, Y., Sillerud, L. O., Meehan, W. P., III, et al. (2018) · Frontiers in Neurology · doi:10.3389/fneur.2018.00451 · Cited by 28

Cognitive deficits in a rat model of temporal lobe epilepsy using touchscreen‐based translational tools

Carron, S. F., Dezsi, G., Öztürk, E., Nithianantharajah, J., & Jones, N. C. (2019) · Epilepsia · doi:10.1111/epi.16291 · Cited by 28

Visual Sequences Drive Experience-Dependent Plasticity in Mouse Anterior Cingulate Cortex

Sidorov, M. S., Kim, H., Rougié, M., Williams, B., Siegel, J. J., Gavornik, J. P., & Philpot, B. D. (2020) · Cell Reports · doi:10.1016/j.celrep.2020.108152 · Cited by 31

Repetitive and compulsive‐like behaviors lead to cognitive dysfunction in Disc1Δ2‐3/Δ2‐3 mice

Wulaer, B., Nagai, T., Sobue, A., Itoh, N., Kuroda, K., Kaibuchi, K., Nabeshima, T., & Yamada, K. (2018) · Genes Brain & Behavior · doi:10.1111/gbb.12478 · Cited by 27

Mice use robust and common strategies to discriminate natural scenes

Yu, Y., Hira, R., Stirman, J. N., Yu, W., Smith, I. T., & Smith, S. L. (2018) · Scientific Reports · doi:10.1038/s41598-017-19108-w · Cited by 29

Mice discriminate between stationary and moving 2D shapes: Application to the object recognition task to increase attention

Braida, D., Donzelli, A., Martucci, R., Ponzoni, L., Pauletti, A., Langus, A., & Sala, M. (2013) · Behavioural Brain Research · doi:10.1016/j.bbr.2012.12.040 · Cited by 26

Characterization of exploratory activity and learning ability of healthy and “schizophrenia-like” rats in a square corridor system (AMBITUS)

Horváth, G., Liszli, P., Kékesi, G., Büki, A., & Benedek, G. (2016) · Physiology & Behavior · doi:10.1016/j.physbeh.2016.11.039 · Cited by 26

Behavioral models in psychopathology: epistemic and semantic considerations

Maximino, C., & van der Staay, F. J. (2019) · Behavioral and Brain Functions · doi:10.1186/s12993-019-0152-4 · Cited by 26

Impaired Reversal Learning in APPPS1-21 Mice in the Touchscreen Visual Discrimination Task

den Broeck, L. V., Hansquine, P., Callaerts‐Vegh, Z., & D’Hooge, R. (2019) · Frontiers in Behavioral Neuroscience · doi:10.3389/fnbeh.2019.00092 · Cited by 28

Learning and reaction times in mouse touchscreen tests are differentially impacted by mutations in genes encoding postsynaptic interacting proteins SYNGAP1, NLGN3, DLGAP1, DLGAP2 and SHANK2

Horner, A. E., Norris, R. H., McLaren‐Jones, R., Alexander, L., Komiyama, N. H., Grant, S. G. N., Nithianantharajah, J., & Kopanitsa, M. V. (2021) · Genes, Brain and Behavior · doi:10.1111/gbb.12723 · Cited by 26

Re-evaluating the PCP challenge as a pre-clinical model of impaired cognitive flexibility in schizophrenia

Fellini, L., Kumar, G., Gibbs, S., Steckler, T., & Talpos, J. C. (2014) · European Neuropsychopharmacology · doi:10.1016/j.euroneuro.2014.08.012 · Cited by 25

Dorso-Lateral Frontal Cortex of the Ferret Encodes Perceptual Difficulty during Visual Discrimination

Zhou, Z. C., Yu, C., Sellers, K. K., & Frӧhlich, F. (2016) · Scientific Reports · doi:10.1038/srep23568 · Cited by 27

Haploinsufficiency of EHMT1 improves pattern separation and increases hippocampal cell proliferation

Benevento, M., Oomen, C. A., Horner, A. E., Amiri, H., Jacobs, T., Pauwels, C., Frega, M., Kleefstra, T., Kopanitsa, M. V., Grant, S. G. N., et al. (2017) · Scientific Reports · doi:10.1038/srep40284 · Cited by 25

Visual discrimination impairment after experimental stroke is associated with disturbances in the polarization of the astrocytic aquaporin-4 and increased accumulation of neurotoxic proteins

Sanchez‐Bezanilla, S., TeBay, C., Nilsson, M., Walker, F. R., & Ong, L. K. (2019) · Experimental Neurology · doi:10.1016/j.expneurol.2019.05.001 · Cited by 25

Early-life stress induces cognitive disorder in middle-aged mice

Yajima, H., Haijima, A., Khairinisa, M. A., Shimokawa, N., Amano, I., & Takatsuru, Y. (2018) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2017.12.021 · Cited by 24

Comparing the effects of subchronic phencyclidine and medial prefrontal cortex dysfunction on cognitive tests relevant to schizophrenia

McAllister, K. A. L., Mar, A. C., Theobald, D. E. H., Saksida, L. M., & Bussey, T. J. (2015) · Psychopharmacology · doi:10.1007/s00213-015-4018-7 · Cited by 24

Performance of C57BL/6J and DBA/2J mice on a touchscreen-based attentional set-shifting task

Dickson, P. E., Calton, M. A., & Mittleman, G. (2013) · Behavioural Brain Research · doi:10.1016/j.bbr.2013.12.015 · Cited by 24

Bridging the species gap in translational research for neurodevelopmental disorders

Ryan, A. M., Berman, R. F., & Bauman, M. D. (2018) · Neurobiology of Learning and Memory · doi:10.1016/j.nlm.2018.10.006 · Cited by 25

Atrx Deletion in Neurons Leads to Sexually Dimorphic Dysregulation of miR-137 and Spatial Learning and Memory Deficits

Tamming, R. J., Dumeaux, V., Jiang, Y. Y., Shafiq, S., Langlois, L., Ellegood, J., Qiu, L. R., Lerch, J. P., & Bérubé, N. G. (2020) · Cell Reports · doi:10.1016/j.celrep.2020.107838 · Cited by 24

Touchscreen-enhanced visual learning in rats

Cook, R. G., Geller, A. I., Zhang, G., & Gowda, R. (2004) · Behavior Research Methods, Instruments, & Computers · doi:10.3758/bf03195555 · Cited by 54

The touchscreen operant platform for testing learning and memory in rats and mice

Horner, A. E., Heath, C. J., Hvoslef‐Eide, M., Kent, B. A., Kim, C. H., Nilsson, S. R. O., Alsiö, J., Oomen, C. A., Holmes, A., Saksida, L. M., et al. (2013) · Nature Protocols · doi:10.1038/nprot.2013.122 · Cited by 412

A COMPUTER TOUCH‐SCREEN APPARATUS FOR TRAINING VISUAL DISCRIMINATIONS IN RATS

Markham, M. R., Butt, A. E., & Dougher, M. J. (1996) · Journal of the Experimental Analysis of Behavior · doi:10.1901/jeab.1996.65-173 · Cited by 44

SPECIAL SESSION The Development of a Diverse Battery of Behavioral Tasks Using Touchscreen Equipped Operant Boxes for the Study of Cognition in the Rodent

Talpos, J. C. (2012)

Strain-dependent effects on acquisition and reversal of visual and spatial tasks in a rat touchscreen battery of cognition

Kumar, G., Talpos, J., & Steckler, T. (2015) · Physiology & Behavior · doi:10.1016/j.physbeh.2015.03.001 · Cited by 51