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Cited by 659

The DOI matches its Crossref record; 20 of the 20 references it cites were found in a registry or an index.

Gait Assessment in Parkinson's Disease: Toward an Ambulatory System for Long-Term Monitoring

Open access
Salarian, A., Russmann, H., Vingerhoets, F.J.G., Dehollain, C., Blanc, Y., Burkhard, P.R., Aminian, K.·2004·IEEE Transactions on Biomedical Engineering
DOI 10.1109/tbme.2004.827933
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Abstract

An ambulatory gait analysis method using body-attached gyroscopes to estimate spatio-temporal parameters of gait has been proposed and validated against a reference system for normal and pathologic gait. Later, ten Parkinson's disease (PD) patients with subthalamic nucleus deep brain stimulation (STN-DBS) implantation participated in gait measurements using our device. They walked one to three times on a 20-m walkway. Patients did the test twice: once STN-DBS was ON and once 180 min after turning it OFF. A group of ten age-matched normal subjects were also measured as controls. For each gait cycle, spatio-temporal parameters such as stride length (SL), stride velocity (SV), stance (ST), double support (DS), and gait cycle time (GC) were calculated. We found that PD patients had significantly different gait parameters comparing to controls. They had 52% less SV, 60% less SL, and 40% longer GC. Also they had significantly longer ST and DS (11% and 59% more, respectively) than controls. STN-DBS significantly improved gait parameters. During the stim ON period, PD patients had 31% faster SV, 26% longer SL, 6% shorter ST, and 26% shorter DS. GC, however, was not significantly different. Some of the gait parameters had high correlation with Unified Parkinson's Disease Rating Scale (UPDRS) subscores including SL with a significant correlation (r = -0.90) with UPDRS gait subscore. We concluded that our method provides a simple yet effective way of ambulatory gait analysis in PD patients with results confirming those obtained from much more complex and expensive methods used in gait labs.

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Metadata

Authors
Salarian, A., Russmann, H., Vingerhoets, F. J. G., Dehollain, C., Blanc, Y., Burkhard, P. R., & Aminian, K.
Venue
IEEE Transactions on Biomedical Engineering
Publisher
Institute of Electrical and Electronics Engineers (IEEE)
Published
2004-08
Volume
51
Issue
8
Pages
1434-1443
ISSN
0018-9294 (ISSN-L)
DOI
10.1109/tbme.2004.827933
OpenAlex
W2162908184
Cited by
659
References
20
FWCI
15.59
Type
journal article
Language
en
Open access
green

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