ESCMID guideline for the diagnosis and management of Candida diseases 2012: diagnostic procedures.
Open accessAbstract
As the mortality associated with invasive Candida infections remains high, it is important to make optimal use of available diagnostic tools to initiate antifungal therapy as early as possible and to select the most appropriate antifungal drug. A panel of experts of the European Fungal Infection Study Group (EFISG) of the European Society of Clinical Microbiology and Infectious Diseases (ESCMID) undertook a data review and compiled guidelines for the clinical utility and accuracy of different diagnostic tests and procedures for detection of Candida infections. Recommendations about the microbiological investigation and detection of candidaemia, invasive candidiasis, chronic disseminated candidiasis, and oropharyngeal, oesophageal, and vaginal candidiasis were included. In addition, remarks about antifungal susceptibility testing and therapeutic drug monitoring were made.
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The echinocandins display in vitro fungicidal activity against most Candida species.
“They display in vitro fungicidal activity against most Candida species, attractive tolerability and pharmacokinetic profiles, and have been recommended as first line agents for invasive candidiasis (1–6).”
From Echinocandin resistance: an emerging clinical problem? (2014) · cites this paper as [2]
The echinocandins have been recommended as first-line agents for invasive candidiasis.
“They display in vitro fungicidal activity against most Candida species, attractive tolerability and pharmacokinetic profiles, and have been recommended as first line agents for invasive candidiasis (1–6).”
From Echinocandin resistance: an emerging clinical problem? (2014) · cites this paper as [2]
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- Authors
- Cuenca-Estrella, M., Verweij, P. E., Arendrup, M. C., Arikan-Akdagli, S., Bille, J., Donnelly, J. P., Jensen, H. E., Lass-Flörl, C., Richardson, M. D., Akova, M., Bassetti, M., Calandra, T., Castagnola, E., Cornely, O. A., Garbino, J., Groll, A. H., Herbrecht, R., Hope, W. W., Kullberg, B. J., Lortholary, O., Meersseman, W., Petrikkos, G., Roilides, E., Viscoli, C., & Ullmann, A. J.
- Affiliations
- Radboud University Nijmegen (NL)
- Statens Serum Institut (DK)
- University of Copenhagen (DK)
- Manchester Academic Health Science Centre (GB)
- Hacettepe University (TR)
- Ospedale Santa Maria della Misericordia di Udine (IT)
- Centre Hospitalier Universitaire Vaudois (CH)
- Istituto Giannina Gaslini (IT)
- University of Cologne (DE)
- University Hospital of Geneva (CH)
- University Hospital Münster (DE)
- Hôpital d'Hautepierre (FR)
- University of Liverpool (GB)
- Hôpital Necker-Enfants Malades (FR)
- Universitair Ziekenhuis Leuven (BE)
- National and Kapodistrian University of Athens (GR)
- Aristotle University of Thessaloniki (GR)
- University of Genoa (IT)
- University of Würzburg (DE)
- Corresponding author
- Ullmann, A. J
- ORCID
- Venue
- Clinical Microbiology and Infection
- Publisher
- Elsevier BV
- Published
- 2012-12
- Volume
- 18
- Pages
- 9-18
- ISSN
- 1198-743X (ISSN-L)
- OpenAlex
- W2161019652
- Cited by
- 386
- References
- 58
- Citations by year
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- FWCI
- 20.76
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
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- PubMed (publishedVersion)
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- Research at the University of Copenhagen (University of Copenhagen) (publishedVersion)
- Institutional Research Information System (University of Udine) (submittedVersion)
- CINECA IRIS Institutial Research Information System (University of Genoa) (submittedVersion)
- IRIS (submittedVersion)
- Hacettepe University Institutional Repository (hacettepe.edu.tr) (submittedVersion, other-oa)
- Radboud Repository (Radboud University) (submittedVersion)
- SERVAL (Université de Lausanne) (submittedVersion)
- Funders
- National Institute for Health and Care Research (CS/08/08/10)
- Topics
- Health Sciences › Medicine › Infectious Diseases › Antifungal resistance and susceptibility
- Health Sciences › Medicine › Epidemiology › Fungal Infections and Studies
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Yeasts and Rust Fungi Studies
- Keywords
- candidiasis, candidemia, invasive candidiasis, chronic disseminated candidiasis, oropharyngeal candidiasis, esophageal candidiasis, vaginal candidiasis, diagnostic testing, antifungal susceptibility testing, therapeutic drug monitoring
- MeSH terms
- Antifungal Agents, Candida, Candidiasis, Humans, Microbial Sensitivity Tests, Biomarkers, Evidence-Based Medicine
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
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