Sociodemographic, clinical, and functional long‐term outcomes in adolescents and young adults with mental disorders

Asselmann, E.; Wittchen, H.‐U.; Lieb, R.; Beesdo‐Baum, K.

doi:10.1111/acps.12792

Cited by 112Mental Health Treatment and AccessChild and Adolescent Psychosocial and Emotional DevelopmentPersonality Disorders and Psychopathology

Sociodemographic, clinical, and functional long‐term outcomes in adolescents and young adults with mental disorders

Asselmann, E., Wittchen, H.‐U., Lieb, R., Beesdo‐Baum, K.·2018·Acta Psychiatrica Scandinavica

DOI 10.1111/acps.12792

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Abstract

Objective: To examine unfavorable sociodemographic, clinical, and functional long‐term outcomes for a range of adolescent mental disorders. Methods: A total number of 2210 adolescents and young adults (14–24 years at baseline, T0) from a representative community sample were prospectively followed up (T1–T3) over 10 years. DSM ‐ IV mental disorders, sociodemographic, clinical, and functional outcomes were assessed using the DIA ‐X/M‐ CIDI and its embedded assessment modules. Results: In (multinomial) logistic regressions adjusted for sex, age, other baseline disorders and sociodemographics, baseline anxiety, affective, substance use, somatoform and eating disorders (lifetime) predicted various unfavorable sociodemographic, clinical, and functional outcomes at T3. Particularly, strong associations were found between baseline disorders and adverse clinical outcomes at T3 (12‐month diagnosis of the same/other disorder(s), drug use, suicide attempts, and help‐seeking due to psychological problems). While substance use disorders were primarily associated with unfavorable sociodemographic and educational outcomes, anxiety and eating disorders were associated with unfavorable interpersonal outcomes, affective disorders with pregnancy‐/childbirth‐related complications and financial issues, and somatoform disorders with unfavorable educational/occupational and interpersonal outcomes. The risk of unfavorable outcomes increased with clinical severity, especially a higher number of baseline diagnoses. Conclusions: Our findings emphasize the importance of effective treatment of mental disorders to prevent unfavorable long‐term outcomes in various life domains.

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Adolescent anxiety disorders are linked to significant short- and long-term impairments across a broad spectrum of life domains.
“Adolescent ADs have also been linked to significant short and long-term impairments across a broad spectrum of life domains [13–16].”
From Acceptance and commitment therapy as a transdiagnostic approach to adolescents with different anxiety disorders: study protocol. (2025) · cites this paper as [14]
Adolescence is a critical phase of human development where mental health problems, particularly anxiety disorders, are highly prevalent and often persist and/or develop into other disorders throughout an individual's life.
“Adolescence is a critical phase of human development where mental health problems, particularly ADs, are highly prevalent (e.g., [3, 4]) and often persist and/or develop into other disorders throughout an individual's life (e.g., [14, 21]).”
From Acceptance and commitment therapy as a transdiagnostic approach to adolescents with different anxiety disorders: study protocol. (2025) · cites this paper as [14]

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Case Study in Youth Flexible Assertive Community Treatment: An Illustration of the Need for Integrated Care
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Prevention and Treatment of Social Anxiety Disorder in Adolescents: Protocol for a Randomized Controlled Trial of the Online Guided Self-Help Intervention SOPHIE
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Assessing the Feasibility of a Peer Education Project to Improve Mental Health Literacy in Adolescents in the UK
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Long-term effectiveness and trajectories of change after treatment with SMART, a transdiagnostic CBT for adolescents with emotional problems
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Internalizing Symptom Profiles Among Youth in Foster Care: A Comparison Study
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Somatoforme Störungen - der Körper spiegelt die Last der Seele
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Social Disability and Impairment in Childhood Anxiety
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Der Abschied von den somatoformen Störungen: Neuerungen durch die Einführung der somatischen Belastungsstörung in ICD-11
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How resilient are former CBT patients with generalized anxiety disorder in times of COVID-19? A follow-up study considering post-treatment depressive symptoms
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Social processes as the missing link: cross-sectionally testing a conceptual model on social mediators of early psychopathological development
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El apoyo social promueve la salud mental durante la pandemia COVID-19
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Outcomes and outcome measurement instruments reported in randomised controlled trials of anxiety disorder treatments in children and adolescents: a scoping review protocol
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Depression in the Paediatric Population: Current Therapeutic Context and Challenges to Innovation
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Comparative Associations between Substances Used with Depression and Anxiety in a Sample of High School Students in Turkey
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Pediatrik Hastada Dental Anksiyete ve Bilişsel Davranışçı Terapi Yöntemi
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What Educators Should Know About Medication Use for Students With Emotional and Behavioral Disorders
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Authors: Asselmann, E., Wittchen, H. ‐., Lieb, R., & Beesdo‐Baum, K.
Affiliations: Technische Universität Dresden (DE)
Institute of Clinical Psychology and Psychotherapy Technische Universität Dresden Dresden Germany
University of Basel (CH)
Corresponding author: Asselmann, E.
ORCID: Asselmann, E.
Lieb, R.
Beesdo‐Baum, K.
Venue: Acta Psychiatrica Scandinavica
Publisher: Wiley
Published: 2017-08-31
Volume: 137
Issue: 1
Pages: 6-17
ISSN: 0001-690X (ISSN-L)
1600-0447
DOI: 10.1111/acps.12792
OpenAlex: W2751055149
Cited by: 112
References: 63
Citations by year: 2026: 16 · 2025: 13 · 2024: 19 · 2023: 11 · 2022: 20 · 2021: 15 · 2020: 9 · 2019: 4 · 2018: 4 · 2017: 1
FWCI: 7.05
Type: journal article
Language: en
Open access: closed
Licence: onlinelibrary.wiley.com/termsAndConditions#vor (vor)
Locations: Acta Psychiatrica Scandinavica (publishedVersion)
PubMed (publishedVersion)
MPG.PuRe (Max Planck Society) (submittedVersion)
Funders: Bundesministerium für Bildung und Forschung (01EB9405/6, 01EB 9901/6, EB01016200, 01EB0140, 01EB0440, 01ER1303, 01ER1703)
Deutsche Forschungsgemeinschaft (LA1148/1‐1, WI2246/1‐1, WI 709/7‐1, WI 709/8‐1)
Topics: Social Sciences › Psychology › Social Psychology › Mental Health Treatment and Access
Social Sciences › Psychology › Clinical Psychology › Child and Adolescent Psychosocial and Emotional Development
Social Sciences › Psychology › Clinical Psychology › Personality Disorders and Psychopathology
Keywords: adolescent mental disorders, young adults, long-term outcomes, substance use disorders, anxiety disorders, eating disorders, somatoform disorders, mood disorders, suicide attempts, help-seeking, educational outcomes, occupational outcomes, interpersonal functioning, financial problems, pregnancy and childbirth complications, comorbidities, clinical severity
MeSH terms: Help-Seeking Behavior, Adolescent, Adult, Anxiety Disorders, Feeding and Eating Disorders, Mental Disorders, Divorce, Educational Status, Employment, Female, Humans, Interpersonal Relations, Longitudinal Studies, Male, Pregnancy, Pregnancy Complications, Prospective Studies, Somatoform Disorders, Suicide, Attempted, Logistic Models, Mood Disorders, Substance-Related Disorders, Family Conflict, Young Adult

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Sociodemographic, clinical, and functional long‐term outcomes in adolescents and young adults with mental disorders

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