Treatment of comorbid alcohol use disorders and depression with cognitive‐behavioural therapy and motivational interviewing: a meta‐analysis

Riper, Heleen; Andersson, Gerhard; Hunter, Sarah B.; Wit, Jessica; Berking, Matthias; Cuijpers, Pim

doi:10.1111/add.12441

Cited by 276Substance Abuse Treatment and OutcomesAnxiety, Depression, Psychometrics, Treatment, Cognitive ProcessesPsychotherapy Techniques and Applications

Treatment of comorbid alcohol use disorders and depression with cognitive‐behavioural therapy and motivational interviewing: a meta‐analysis

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Riper, Heleen, Andersson, Gerhard, Hunter, Sarah B., Wit, Jessica, Berking, Matthias, Cuijpers, Pim·2014·Addiction

DOI 10.1111/add.12441PMC PMC4227588

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Abstract

BACKGROUND AND AIMS: To review published studies on the effectiveness of combining cognitive-behavioural therapy (CBT) and motivational interviewing (MI) to treat comorbid clinical and subclinical alcohol use disorder (AUD) and major depression (MDD) and estimate the effect of this compared with usual care. METHODS: We conducted systematic literature searches in PubMed, PsycINFO and Embase up to June 2013 and identified additional studies through cross-references in included studies and systematic reviews. Twelve studies comprising 1721 patients met our inclusion criteria. The studies had sufficient statistical power to detect small effect sizes. RESULTS: CBT/MI proved effective for treating subclinical and clinical AUD and MDD compared with controls, with small overall effect sizes at post-treatment [g=0.17, confidence interval (CI)=0.07-0.28, P<0.001 for decrease of alcohol consumption and g=0.27, CI: 0.13-0.41, P<0.001 for decrease of symptoms of depression, respectively]. Subgroup analyses revealed no significant differences for both AUD and MDD. However, digital interventions showed a higher effect size for depression than face-to-face interventions (g= 0.73 and g=0.23, respectively, P=0.030). CONCLUSIONS: Combined cognitive-behavioural therapy and motivational interviewing for clinical or subclinical depressive and alcohol use disorders has a small but clinically significant effect in treatment outcomes compared with treatment as usual.

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CBT is the standard of care for many psychiatric disorders including depression, anxiety disorders, eating disorders, addiction, chronic pain and sleeping disturbance (insomnia) across the spectrum of acuity.
“CBT is the standard of care for many psychiatric disorders including depression, anxiety disorders, eating disorders, addiction, chronic pain and sleeping disturbance (insomnia) across the spectrum of acuity.16–20”
From A study protocol for a non-randomised comparison trial evaluating the feasibility and effectiveness of a mobile cognitive-behavioural programme with integrated coaching for anxious adults in primary care (2018) · cites this paper as [16]
The Introduction describes CBT as effective for depression and alcohol use disorders, and the Discussion reports small but significant effects of combined CBT and motivational interviewing for people with both conditions (page numbers unavailable). The paper does not establish CBT as the standard of care, or address its use for eating disorders, chronic pain, insomnia, or the full spectrum of acuity. (LLM, conf=0.88)
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Treatment of Comorbid Alcohol Use Disorders and Depression with Cognitive-Behavioural Therapy and Motivational Interviewing
Riper, H. M., Andersson, G., Hunter, S. B., de Wit, J., Berking, M., & Cuijpers, P. J. (2014) · Cited by 3 · see citing works
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Authors: Riper, H., Andersson, G., Hunter, S. B., Wit, J., Berking, M., & Cuijpers, P.
Affiliations: Leuphana University of Lüneburg (DE)
Linköping University (SE)
RAND Corporation (US)
Vrije Universiteit Amsterdam (NL)
Amsterdam Public Health (NL)
Corresponding author: Riper, Heleen
ORCID: Riper, Heleen
Andersson, Gerhard
Hunter, Sarah B.
Berking, Matthias
Cuijpers, Pim
Venue: Addiction
Publisher: Wiley
Published: 2014-01-16
Volume: 109
Issue: 3
Pages: 394-406
ISSN: 0965-2140 (ISSN-L)
1360-0443
DOI: 10.1111/add.12441
PMC: PMC4227588
OpenAlex: W1522072170
Cited by: 276
References: 78
Citations by year: 2026: 17 · 2025: 21 · 2024: 11 · 2023: 20 · 2022: 41 · 2021: 29 · 2020: 18 · 2019: 33 · 2018: 28 · 2017: 21 · 2016: 17 · 2015: 12 · 2014: 7 · 2013: 1
FWCI: 1.46
Type: journal article
Language: en
Open access: hybrid
doi.org
Licence: cc-by-nc-nd
creativecommons.org/licenses/by-nc-nd/3.0/ (vor)
doi.wiley.com/10.1002/tdm_license_1.1 (tdm)
Locations: Addiction (publishedVersion, cc-by-nc-nd)
Europe PMC (PubMed Central) (publishedVersion, cc-by-nc-nd)
PubMed Central (publishedVersion, cc-by-nc-nd)
PubMed (publishedVersion)
Pure Amsterdam UMC (publishedVersion)
Amsterdam UMC (VU Amsterdam) - Institutional Repository (publishedVersion)
VU Research Portal (publishedVersion, other-oa)
KTH Publication Database DiVA (KTH Royal Institute of Technology) (submittedVersion, other-oa)
Multilingual Matters (Channel View Publications) (submittedVersion, cc-by-nc-nd)
Data Archiving and Networked Services (DANS) (submittedVersion, other-oa)
Data Archiving and Networked Services (DANS) (submittedVersion)
Topics: Health Sciences › Medicine › Epidemiology › Substance Abuse Treatment and Outcomes
Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
Social Sciences › Psychology › Clinical Psychology › Psychotherapy Techniques and Applications
Keywords: alcoholism, major depressive disorder, comorbidities, cognitive behavioral therapy, motivational interviewing, combined psychotherapy, digital interventions, alcohol consumption, depressive symptoms
MeSH terms: Major Depressive Disorder, Humans, Cognitive Behavioral Therapy, Treatment Outcome, Alcohol-Related Disorders, Motivational Interviewing

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Treatment of comorbid alcohol use disorders and depression with cognitive‐behavioural therapy and motivational interviewing: a meta‐analysis

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