The DOI matches its Crossref record; 9 of the 9 references it cites were found in a registry or an index.
Physiological role of taurine – from organism to organelle
Abstract
Taurine is often referred to as a semi‐essential amino acid as newborn mammals have a limited ability to synthesize taurine and have to rely on dietary supply. Taurine is not thought to be incorporated into proteins as no aminoacyl tRNA synthetase has yet been identified and is not oxidized in mammalian cells. However, taurine contributes significantly to the cellular pool of organic osmolytes and has accordingly been acknowledged for its role in cell volume restoration following osmotic perturbation. This review describes taurine homeostasis in cells and organelles with emphasis on taurine biophysics/membrane dynamics, regulation of transport proteins involved in active taurine uptake and passive taurine release as well as physiological processes, for example, development, lung function, mitochondrial function, antioxidative defence and apoptosis which seem to be affected by a shift in the expression of the taurine transporters and/or the cellular taurine content.
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Cites
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Self-citationCaffeinated energy drinks a growing problem
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Cited by
Taurine deficiency as a driver of aging
Singh, P., Gollapalli, K., Mangiola, S., Schranner, D., Yusuf, M. A., Chamoli, M., Shi, S. L., Lopes Bastos, B., Nair, T., Riermeier, A., et al. (2023) · Science · doi:10.1126/science.abn9257 · Cited by 435
VRACs and other ion channels and transporters in the regulation of cell volume and beyond
Jentsch, T. J. (2016) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm.2016.29 · Cited by 353
Taurocholic acid metabolism by gut microbes and colon cancer
Ridlon, J. M., Wolf, P. G., & Gaskins, H. R. (2016) · Gut Microbes · doi:10.1080/19490976.2016.1150414 · Cited by 327
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Taurine: the appeal of a safe amino acid for skeletal muscle disorders
De Luca, A., Pierno, S., & Camerino, D. C. (2015) · Journal of Translational Medicine · doi:10.1186/s12967-015-0610-1 · Cited by 253
Metadata
- Authors
- Lambert, I. H., Kristensen, D. M., Holm, J. B., & Mortensen, O. H.
- Venue
- Acta Physiologica
- Publisher
- Wiley
- Published
- 2014-09-12
- Volume
- 213
- Issue
- 1
- Pages
- 191-212
- ISSN
- 1748-1708 (ISSN-L)
- 1748-1716
- OpenAlex
- W2052225210
- Cited by
- 360
- References
- 9
- FWCI
- 10.59
- Type
- journal article
- Language
- en
- Open access
- closed
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- Lambert, I. H., Kristensen, D. M., Holm, J. B., & Mortensen, O. H. (2015). Physiological role of taurine – from organism to organelle. Acta Physiologica. https://doi.org/10.1111/apha.12365
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
