Cited by 93Diabetes Management and EducationMental Health Treatment and AccessDiabetes, Cardiovascular Risks, and Lipoproteins

The association between diabetes and an episode of depressive symptoms in the 2002 world health survey: an analysis of 231,797 individuals from 47 countries

Mommersteeg, P. M. C., Herr, R., Pouwer, F., Holt, R. I. G., Loerbroks, A.·2013·Diabetic Medicine

Abstract

AIMS: Depression is common in people with diabetes and increases the risk of poor health outcomes, including premature mortality. We explored the association between diabetes and an episode of depressive symptoms in a cross-sectional multinational study, which included a large number of low- and middle-income non-Western countries. METHODS: Data from 47 countries of the 2002 World Health Organization World Health Survey were used, including 231,797 adults (mean age 41 years, 53% female). Diabetes was assessed by self-report of diagnosis or treatment. The presence of an episode of depressive symptoms was assessed by self-report using an algorithm based on DSM-IV criteria. Odds ratios and 95% confidence intervals were calculated to quantify associations between diabetes and episodes of depressive symptoms in the entire sample and for countries aggregated into four continents: Africa, South America, Asia and Europe. Odds ratios were adjusted for age, sex, education, BMI, smoking and physical activity level. RESULTS: The prevalence of diabetes (mean 3.6%, range 0.2-13%) and episodes of depressive symptoms (mean 7.9%, range 0.4-38%) differed widely across countries. Globally, individuals with diabetes had increased odds of an episode of depressive symptoms compared with those without diabetes (adjusted odds ratio 2.36, 95% confidence interval 1.91-2.92). Similar associations were found in South America, Asia and Europe (odds ratio > 1.97), but not in Africa (odds ratio 0.86, 95% confidence interval 0.54-1.37). CONCLUSIONS: Globally, diabetes is associated with a twofold increased prevalence of an episode of depressive symptoms, except in Africa. Given the worldwide rise in diabetes in the coming decades, and the increased risk of poor diabetes outcomes associated with co-morbid depression, studies examining mechanisms and interventions are necessary.

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Crossref · 10.1111/dme.12193

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Authors
Mommersteeg, P. M. C., Herr, R., Pouwer, F., Holt, R. I. G., & Loerbroks, A.
Affiliations
  • Tilburg University (NL)
  • Heidelberg University (DE)
  • University of Southampton (GB)
Corresponding author
Mommersteeg, P. M. C.
Venue
Diabetic Medicine
Publisher
Wiley
Published
2013-04-25
Volume
30
Issue
6
Pages
e208-14
ISSN
  • 0742-3071 (ISSN-L)
  • 1464-5491
OpenAlex
W2117239701
Cited by
93
References
28
Citations by year
2026: 3 · 2025: 4 · 2024: 9 · 2023: 15 · 2022: 3 · 2021: 5 · 2020: 9 · 2019: 3 · 2018: 8 · 2017: 8 · 2016: 6 · 2015: 8 · 2014: 7 · 2013: 5
FWCI
6.82
Type
journal article
Language
en
Open access
closed
Locations
  • Diabetic Medicine (publishedVersion)
  • Research portal (Tilburg University) (publishedVersion)
  • PubMed (publishedVersion)
  • Data Archiving and Networked Services (DANS) (submittedVersion)
  • ePrints Soton (University of Southampton) (submittedVersion)
Funders
International Business Machines Corporation
Topics
  • Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes Management and Education
  • Social Sciences › Psychology › Social Psychology › Mental Health Treatment and Access
  • Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes, Cardiovascular Risks, and Lipoproteins
Keywords
diabetes mellitus, depressive symptoms, depression, comorbidities, prevalence, cross-national comparison, low- and middle-income countries, World Health Survey, mental health
MeSH terms
Adolescent, Adult, Aged, Aged, 80 and over, Cross-Sectional Studies, Depression, Diabetes Mellitus, Female, Health Surveys, Humans, Male, Middle Aged, Risk, Global Health, World Health Organization, Comorbidity, Prevalence, Diagnostic and Statistical Manual of Mental Disorders, Young Adult, Self Report

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