Global burden of depressive disorders in the year 2000
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BACKGROUND: The initial Global Burden of Disease study found that depression was the fourth leading cause of disease burden, accounting for 3.7% of total disability adjusted life years (DALYs) in the world in 1990. AIMS: To present the new estimates of depression burden for the year 2000. METHOD: DALYs for depressive disorders in each world region were calculated, based on new estimates of mortality, prevalence, incidence, average age at onset, duration and disability severity. RESULTS: Depression is the fourth leading cause of disease burden, accounting for 4.4% of total DALYs in the year 2000, and it causes the largest amount of non-fatal burden, accounting for almost 12% of all total years lived with disability worldwide. CONCLUSIONS: These data on the burden of depression worldwide represent a major public health problem that affects patients and society.
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Major depression is a frequently occurring, severely disabling, and often recurring mental disorder.
“Major depression is a commonly occurring, seriously impairing, and often recurrent mental disorder.1, 2”
From The Costs of Depression (2012) · cites this paper as [2]
In GBD 2000, depressive disorders were the leading cause of disability, responsible for 13.4% of YLDs in women and 8.3% in men.
“It was also the leading cause of disability, responsible for 13.4% of YLDs in women and 8.3% in men [8].”
From Burden of depressive disorders by country, sex, age, and year: findings from the Global Burden of Disease Study 2010 (2013) · cites this paper as [8]
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- Authors
- Üstün, T. B., Ayuso-Mateos, J. L., Chatterji, S., Mathers, C., & Murray, C. J. L.
- Affiliations
- World Health Organization (CH)
- Corresponding author
- Üstün, T. B.
- Venue
- British Journal of Psychiatry
- Publisher
- Royal College of Psychiatrists
- Published
- 2004-05
- Volume
- 184
- Issue
- 5
- Pages
- 386-392
- ISSN
- 0007-1250 (ISSN-L)
- 1472-1465
- OpenAlex
- W2145151017
- Cited by
- 1,735
- References
- 37
- Citations by year
- 2026: 13 · 2025: 17 · 2024: 26 · 2023: 54 · 2022: 47 · 2021: 50 · 2020: 59 · 2019: 66 · 2018: 81 · 2017: 126 · 2016: 88 · 2015: 120 · 2014: 124 · 2013: 134 · 2012: 113
- FWCI
- 83.74
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- The British Journal of Psychiatry (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Institutes of Health (5u01mh035883-17)
- National Institute of Mental Health (MH35883)
- Topics
- Social Sciences › Psychology › Social Psychology › Mental Health Treatment and Access
- Health Sciences › Medicine › Pharmacology › Treatment of Major Depression
- Social Sciences › Economics, Econometrics and Finance › Economics and Econometrics › Health Systems, Economic Evaluations, Quality of Life
- Keywords
- depressive disorders, depression, global burden of disease, disability-adjusted life years, years lived with disability, depression prevalence, depression incidence, age of onset, disease duration, disability severity, public health burden
- MeSH terms
- Adult, Depressive Disorder, Disability Evaluation, Female, Humans, Male, Public Health, Global Health, Incidence, Prevalence, Cost of Illness, Quality-Adjusted Life Years
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