A feasibility trial of an Internet‐delivered and transdiagnostic cognitive behavioral therapy treatment program for anxiety, depression, and disability among adults with epilepsy
Abstract
Summary: Objective: Anxiety and depression are highly prevalent in people with epilepsy (PWE) and contribute to increased disability. Unfortunately, there are numerous barriers (e.g., cost, distance, and stigma) and service gaps (e.g., lack of services and trained clinicians) that prevent many PWE from accessing traditional face‐to‐face psychological services. The aim of the present study was to examine the feasibility of a new transdiagnostic Internet‐delivered cognitive behavioral therapy (iCBT) program, the Chronic Conditions Course, to simultaneously treat symptoms of anxiety, depression, and disability. Methods: A single‐group feasibility open trial was employed involving 27 adults with epilepsy. The program comprises five online lessons delivered over 8 weeks and is provided with weekly contact from a mental health professional via e‐mail and telephone. Results: High treatment completion rates and levels of satisfaction were reported. Evidence of significant improvements in our primary outcomes (within‐group Cohen's d [d]; average [avg.] reductions) of anxiety (d ≥ 1.28; avg. reduction ≥ 54%), depression (d ≥ 1.24; avg. reduction ≥ 54%), epilepsy‐specific depression (d ≥ 0.95; avg. reduction ≥ 35%), and disability (d ≥ 0.62; avg. reduction ≥ 33%) were observed at posttreatment, which were sustained at or further improved to 3‐month follow‐up. On our secondary outcomes there were significant improvements for life satisfaction (d ≥ 0.70; avg. improvement ≥ 26%) but not for perceived cognitive difficulties (d ≥ 0.48; avg. reduction ≥ 15%). Highlighting the potential of the approach, relatively little clinician time was required per participant (mean 80.62 min, standard deviation [SD] 54.78), and the trial involved a broad range of geographically dispersed patients. Significance: The findings of the current study support the feasibility and potential of transdiagnostic Internet‐delivered treatments for adults with epilepsy. Further large‐scale controlled trials are warranted.
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The possibility to recruit patients without geographical barriers presents opportunities for testing psychotherapy for people with conditions that are highly disabling but have relatively low prevalence, making them difficult to study feasibly in face-to-face trials.
“The possibility to recruit patients without geographical bar riers also presents opportunities for testing psychotherapy for people with conditions and problems (e.g., spinal cord injury, epilepsy) that can be highly disabling while also having a rela tively low prevalence, making them very difficult to study fea sibly in facetoface trials 53 .”
From Internet-delivered psychological treatments: from innovation to implementation (2019) · cites this paper as [53]
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- Authors
- Gandy, M., Karin, E., Fogliati, V. J., McDonald, S., Titov, N., & Dear, B. F.
- Affiliations
- Macquarie University (AU)
- Department of Psychology eCentreClinic Macquarie University Sydney New South Wales Australia
- Corresponding author
- Gandy, Milena
- Venue
- Epilepsia
- Publisher
- Wiley
- Published
- 2016-10-07
- Volume
- 57
- Issue
- 11
- Pages
- 1887-1896
- ISSN
- 0013-9580 (ISSN-L)
- 1528-1167
- OpenAlex
- W2528208604
- Cited by
- 41
- References
- 40
- Citations by year
- 2026: 4 · 2024: 4 · 2023: 5 · 2022: 3 · 2021: 5 · 2020: 7 · 2019: 5 · 2018: 3 · 2017: 5
- FWCI
- 6.68
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Epilepsia (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Macquarie University
- National Health and Medical Research Council
- Topics
- Social Sciences › Psychology › Applied Psychology › Digital Mental Health Interventions
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Telemedicine and Telehealth Implementation
- Keywords
- epilepsy, internet-based cognitive behavioral therapy, transdiagnostic treatment, anxiety, depression, disability, treatment feasibility, life satisfaction, cognitive difficulties, access to mental health care, telemedicine
- MeSH terms
- Adult, Aged, Aged, 80 and over, Anxiety, Depression, Epilepsy, Feasibility Studies, Female, Persons with Disabilities, Disabled Persons, Humans, Male, Middle Aged, Psychiatric Status Rating Scales, Cognitive Behavioral Therapy, Treatment Outcome, Internet, Young Adult
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