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Cannabinoids for treatment of chronic non‐cancer pain; a systematic review of randomized trials
Open accessAbstract
Effective therapeutic options for patients living with chronic pain are limited. The pain relieving effect of cannabinoids remains unclear. A systematic review of randomized controlled trials (RCTs) examining cannabinoids in the treatment of chronic non‐cancer pain was conducted according to the PRISMA statement update on the QUORUM guidelines for reporting systematic reviews that evaluate health care interventions. Cannabinoids studied included smoked cannabis, oromucosal extracts of cannabis based medicine, nabilone, dronabinol and a novel THC analogue. Chronic non‐cancer pain conditions included neuropathic pain, fibromyalgia, rheumatoid arthritis, and mixed chronic pain. Overall the quality of trials was excellent. Fifteen of the eighteen trials that met the inclusion criteria demonstrated a significant analgesic effect of cannabinoid as compared with placebo and several reported significant improvements in sleep. There were no serious adverse effects. Adverse effects most commonly reported were generally well tolerated, mild to moderate in severity and led to withdrawal from the studies in only a few cases. Overall there is evidence that cannabinoids are safe and modestly effective in neuropathic pain with preliminary evidence of efficacy in fibromyalgia and rheumatoid arthritis. The context of the need for additional treatments for chronic pain is reviewed. Further large studies of longer duration examining specific cannabinoids in homogeneous populations are required. Linked Article This article is linked to a themed issue in the British Journal of Pharmacology on Respiratory Pharmacology. To view this issue visit http://dx.doi.org/10.1111/bph.2011.163.issue‐1
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“In one recent review of published studies on non-cancer pain, cannabinoids appeared to have proven safety and modest efficacy in the treatment of neuropathic pain whereas, there are some evidences of efficacy also in fibromyalgia and rheumatoid arthritis [19].”
From Nabilone for the treatment of medication overuse headache: results of a preliminary double-blind, active-controlled, randomized trial (2012) · cites this paper as [19]
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Liberati, A., Altman, D. G., Tetzlaff, J., Mulrow, C., Gøtzsche, P. C., Ioannidis, J. P. A., Clarke, M., Devereaux, P. J., Kleijnen, J., & Moher, D. (2009) · PLoS Medicine · doi:10.1371/journal.pmed.1000100 · Cited by 28,164
Assessing the quality of reports of randomized clinical trials: Is blinding necessary?
Jadad, A. R., Moore, R. A., Carroll, D., Jenkinson, C., Reynolds, D. J. M., Gavaghan, D. J., & McQuay, H. J. (1996) · Controlled Clinical Trials · doi:10.1016/0197-2456(95)00134-4 · Cited by 17,582
Liberati, A., Altman, D. G., Tetzlaff, J., Mulrow, C., Gøtzsche, P. C., Ioannidis, J. P. A., Clarke, M., Devereaux, P. J., Kleijnen, J., & Moher, D. (2009) · Journal of Clinical Epidemiology · doi:10.1016/j.jclinepi.2009.06.006 · Cited by 10,578
Survey of chronic pain in Europe: Prevalence, impact on daily life, and treatment
Breivik, H., Collett, B., Ventafridda, V., Cohen, R., & Gallacher, D. (2006) · European Journal of Pain · doi:10.1016/j.ejpain.2005.06.009 · Cited by 5,486
Tsang, A., Von Korff, M., Lee, S., Alonso, J., Karam, E., Angermeyer, M. C., Borges, G. L. G., Bromet, E. J., de Girolamo, G., de Graaf, R., et al. (2008) · The Journal of Pain · doi:10.1016/j.jpain.2008.05.005 · Cited by 1,157
Chronic pain in Australia: a prevalence study.
Blyth, F. M., March, L. M., Brnabic, A. J. M., Jorm, L. R., Williamson, M., & Cousins, M. J. (2001) · Pain · doi:10.1016/s0304-3959(00)00355-9 · Cited by 1,096
Opioids for chronic noncancer pain: A meta-analysis of effectiveness and side effects
Furlan, A. D. (2006) · Canadian Medical Association Journal · doi:10.1503/cmaj.051528 · Cited by 873
Prevalence of undertreatment in cancer pain. A review of published literature
Deandrea, S., Montanari, M., Moja, L., & Apolone, G. (2008) · Annals of Oncology · doi:10.1093/annonc/mdn419 · Cited by 871
Universities and tobacco money
Cohen, J. E. (2001) · British medical journal · doi:10.1136/bmj.323.7303.1 · Cited by 870
Zajicek, J., Fox, P., Sanders, H., Wright, D., Vickery, J., Nunn, A., & Thompson, A. (2003) · The Lancet · doi:10.1016/s0140-6736(03)14738-1 · Cited by 827
Research works printed but not linked: 2
- 10.1001/jama.290.13.1757 · DOI · Paper page
- 10.1016/j.neuropharm.2005.02.010 · DOI · Paper page
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Whiting, P. F., Wolff, R. F., Deshpande, S., Di Nisio, M., Duffy, S., Hernandez, A. V., Keurentjes, J. C., Lang, S., Misso, K., Ryder, S., et al. (2015) · JAMA · doi:10.1001/jama.2015.6358 · Cited by 2,169
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Paice, J. A., Portenoy, R. K., Lacchetti, C., Campbell, T. C., Cheville, A. L., Citron, M. L., Constine, L. S., Cooper, A., Glare, P. A., Keefe, F., et al. (2016) · Journal of Clinical Oncology · doi:10.1200/jco.2016.68.5206 · Cited by 604
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Moulin, D., Boulanger, A., Clark, A., Clarke, H., Dao, T., Finley, G., Furlan, A., Gilron, I., Gordon, A., Morley-Forster, P., et al. (2014) · Pain Research and Management · doi:10.1155/2014/754693 · Cited by 529
Aizpurua‐Olaizola, O., Soydaner, U., Öztürk, E., Schibano, D., Simsir, Y., Navarro, P., Etxebarría, N., & Usobiaga, A. (2016) · Journal of Natural Products · doi:10.1021/acs.jnatprod.5b00949 · Cited by 487
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Bridgeman, M. B., & Abazia, D. T. (2017) · PubMed Central · Cited by 421
Boehnke, K. F., Litinas, E., & Clauw, D. J. (2016) · The Journal of Pain · doi:10.1016/j.jpain.2016.03.002 · Cited by 412
Fitzcharles, M.-A., Ste-Marie, P. A., Goldenberg, D. L., Pereira, J. X., Abbey, S., Choinière, M., Ko, G., Moulin, D. E., Panopalis, P., Proulx, J., et al. (2013) · Pain Research and Management · doi:10.1155/2013/918216 · Cited by 409
Wen, H., Hockenberry, J. M., & Cummings, J. R. (2015) · Journal of Health Economics · doi:10.1016/j.jhealeco.2015.03.007 · Cited by 378
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Fallon, M. (2013) · British Journal of Anaesthesia · doi:10.1093/bja/aet208 · Cited by 328
Aviram, J. (2017) · Pain Physician · doi:10.36076/ppj.20.5.e755 · Cited by 305
Klauke, A. ‐., Rácz, I., Pradier, B., Markert, A., Zimmer, A., Gertsch, J., & Zimmer, A. (2013) · European Neuropsychopharmacology · doi:10.1016/j.euroneuro.2013.10.008 · Cited by 312
Donvito, G., Nass, S. R., Wilkerson, J. L., Curry, Z. A., Schurman, L. D., Kinsey, S. G., & Lichtman, A. H. (2018) · Neuropsychopharmacology · doi:10.1038/npp.2017.204 · Cited by 301
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Xiong, W., Cui, T., Cheng, K., Yang, F., Chen, S.-R., Willenbring, D., Guan, Y., Pan, H., Ren, K., Xu, Y., et al. (2012) · The Journal of Experimental Medicine · doi:10.1084/jem.20120242 · Cited by 290
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Baron, E. P. (2018) · Headache The Journal of Head and Face Pain · doi:10.1111/head.13345 · Cited by 268
Haroutounian, S., Ratz, Y., Ginosar, Y., Furmanov, K., Saifi, F., Meidan, R., & Davidson, E. (2016) · The Clinical Journal of Pain · doi:10.1097/ajp.0000000000000364 · Cited by 234
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Baron, E. P., Lucas, P., Eades, J., & Hogue, O. (2018) · The Journal of Headache and Pain · doi:10.1186/s10194-018-0862-2 · Cited by 188
Henshaw, F. R., Dewsbury, L. S., Lim, C. K., & Steiner, G. Z. (2021) · Cannabis and Cannabinoid Research · doi:10.1089/can.2020.0105 · Cited by 184
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Allan, G. M., Finley, C. R., Ton, J., Perry, D., Ramji, J., Crawford, K., Lindblad, A. J., Korownyk, C. S., & Kolber, M. R. (2018) · Europe PMC (PubMed Central) · Cited by 139
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Turcotte, D., Doupe, M., Torabi, M., Gomori, A., Ethans, K., Esfahani, F., Galloway, K., & Namaka, M. (2015) · Pain Medicine · doi:10.1111/pme.12569 · Cited by 124
Almog, S., Aharon‐Peretz, J., Vulfsons, S., Ogintz, M., Abalia, H., Lupo, T., Hayon, Y., & Eisenberg, E. (2020) · European Journal of Pain · doi:10.1002/ejp.1605 · Cited by 123
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Pini, L. A., Guerzoni, S., Cainazzo, M. M., Ferrari, A., Sarchielli, P., Tiraferri, I., Ciccarese, M., & Zappaterra, M. (2012) · The Journal of Headache and Pain · doi:10.1007/s10194-012-0490-1 · Cited by 107
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Montero‐Oleas, N., Arévalo-Rodríguez, I., Núñez-González, S., Viteri-García, A. A., & Simancas‐Racines, D. (2020) · BMC Complementary Medicine and Therapies · doi:10.1186/s12906-019-2803-2 · Cited by 98
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Moore, A., Fisher, E., Finn, D. P., Finnerup, N. B., Gilron, I., Haroutounian, S., Krane, E. J., Rice, A. S. C., Rowbotham, M. C., Wallace, M. S., et al. (2020) · Pain · doi:10.1097/j.pain.0000000000001941 · Cited by 83
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Gazendam, A., Nucci, N. W., Gouveia, K., Khalik, H. A., Rubinger, L., & Johal, H. S. (2020) · Cannabis and Cannabinoid Research · doi:10.1089/can.2019.0079 · Cited by 68
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Effects of cannabinoid administration for pain: A meta-analysis and meta-regression.
Yanes, J. A., McKinnell, Z. E., Reid, M. A., Busler, J. N., Michel, J. S., Pangelinan, M. M., Sutherland, M. T., Younger, J., González, R., & Robinson, J. L. (2019) · Experimental and Clinical Psychopharmacology · doi:10.1037/pha0000281 · Cited by 68
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Carcieri, C., Tomasello, C., Simiele, M., Nicolò, A. D., Avataneo, V., Canzoneri, L., Cusato, J., Perri, G. D., & D’Avolio, A. (2017) · Journal of Pharmacy and Pharmacology · doi:10.1111/jphp.12845 · Cited by 64
Medical marijuana: Medical necessity versus political agenda
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Cannabinoids for the Treatment of Agitation and Aggression in Alzheimer’s Disease
Liu, C. S., Chau, S. A., Ruthirakuhan, M. T., Lanctôt, K. L., & Herrmann, N. (2015) · CNS Drugs · doi:10.1007/s40263-015-0270-y · Cited by 63
Aggarwal, S. K. (2013) · The Clinical Journal of Pain · doi:10.1097/ajp.0b013e31824c5e4c · Cited by 62
Therapeutic benefits of cannabis: a patient survey.
Webb, C. W., & Webb, S. M. (2014) · Europe PMC (PubMed Central) · Cited by 61
Troutt, W. D., & DiDonato, M. D. (2015) · Journal of Psychoactive Drugs · doi:10.1080/02791072.2015.1074766 · Cited by 61
Involvement of the endocannabinoid system in osteoarthritis pain
Porta, C. L., Bura, S. A., Negrete, R., & Maldonado, R. J. (2014) · European Journal of Neuroscience · doi:10.1111/ejn.12468 · Cited by 61
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Cannabis and joints: scientific evidence for the alleviation of osteoarthritis pain by cannabinoids
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Clinical Data for the Use of Cannabis-Based Treatments: A Comprehensive Review of the Literature
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Do Medical Marijuana Laws Reduce Addictions and Deaths Related to Pain Killers?
Powell, D., Pacula, R. L., & Jacobson, M. (2015) · National Bureau of Economic Research · doi:10.3386/w21345 · Cited by 56
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Metadata
- Authors
- Lynch, M. E., & Campbell, F.
- Affiliations
- Dalhousie University (CA)
- University of Toronto (CA)
- Corresponding author
- Lynch, Mary E.
- Venue
- British Journal of Clinical Pharmacology
- Publisher
- Wiley
- Published
- 2011-10-11
- Volume
- 72
- Issue
- 5
- Pages
- 735-744
- ISSN
- 0306-5251 (ISSN-L)
- 1365-2125
- PMC
- PMC3243008
- OpenAlex
- W1589884020
- Cited by
- 397
- References
- 62
- Citations by year
- 2026: 17 · 2025: 20 · 2024: 13 · 2023: 19 · 2022: 21 · 2021: 23 · 2020: 25 · 2019: 25 · 2018: 36 · 2017: 28 · 2016: 39 · 2015: 51 · 2014: 35 · 2013: 16 · 2012: 24
- FWCI
- 3.19
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- British Journal of Clinical Pharmacology (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Pharmacology (medical) › Cannabis and Cannabinoid Research
- Health Sciences › Medicine › Physiology (medical) › Pain Mechanisms and Treatments
- Health Sciences › Medicine › Anesthesiology and Pain Medicine › Pain Management and Opioid Use
- Keywords
- cannabinoids, chronic non-cancer pain, neuropathic pain, fibromyalgia, rheumatoid arthritis, cannabis smoking, nabilone, dronabinol, analgesic effect, sleep improvement, adverse effects, tolerability
- MeSH terms
- Cannabinoids, Humans, Neuralgia, Randomized Controlled Trials as Topic, Analgesics, Non-Narcotic, Chronic Pain
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