AMP-activated protein kinase: maintaining energy homeostasis at the cellular and whole-body levels

Repertoires of Autophagy in the Pathogenesis of Ocular Diseases

Li, Y., Jiang, Q. L., Cao, G.-F., Yao, J., & Yan, B. (2015) · Cellular Physiology and Biochemistry · doi:10.1159/000373980 · Cited by 16,351 · see citing works

Inhibition of Prostaglandin Synthesis as a Mechanism of Action for Aspirin-like Drugs

VANE, J. R. (1971) · Nature New Biology · doi:10.1038/newbio231232a0 · Cited by 8,605 · see citing works

AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1

Kim, J., Kundu, M., Viollet, B., & Guan, K.-L. (2011) · Nature Cell Biology · doi:10.1038/ncb2152 · Cited by 7,227 · see citing works

Role of AMP-Activated Protein Kinase in Mechanism of Metformin Action

Zhou, G., Myers, R., Li, Y., Chen, Y., Shen, X., Fenyk-Melody, J., Wu, M., Ventre, J., Doebber, T., Fujii, N., et al. (2001) · Journal of Clinical Investigation · doi:10.1172/jci13505 · Cited by 5,652 · see citing works

Leptin and the regulation of body weight in mammals

Friedman, J. M., & Halaas, J. L. (1998) · Nature · doi:10.1038/27376 · Cited by 5,405 · see citing works

Resveratrol improves health and survival of mice on a high-calorie diet

Baur, J. A., Pearson, K. J., Price, N. L., Jamieson, H. A., Lerin, C., Kalra, A., Prabhu, V. V., Allard, J. S., Lopez-Lluch, G., Lewis, K., et al. (2006) · Nature · doi:10.1038/nature05354 · Cited by 4,290 · see citing works

Adiponectin stimulates glucose utilization and fatty-acid oxidation by activating AMP-activated protein kinase

Yamauchi, T., Kamon, J., Minokoshi, Y., Ito, Y., Waki, H., Uchida, S., Yamashita, S., Noda, M., Kita, S., Ueki, K., et al. (2002) · Nature Medicine · doi:10.1038/nm788 · Cited by 4,238 · see citing works

TSC2 Mediates Cellular Energy Response to Control Cell Growth and Survival

Inoki, K., Zhu, T., & Guan, K.-L. (2003) · Cell · doi:10.1016/s0092-8674(03)00929-2 · Cited by 3,914 · see citing works

AMPK Phosphorylation of Raptor Mediates a Metabolic Checkpoint

Gwinn, D. M., Shackelford, D. B., Egan, D. F., Mihaylova, M. M., Mery, A., Vasquez, D. S., Turk, B. E., & Shaw, R. J. (2008) · Molecular Cell · doi:10.1016/j.molcel.2008.03.003 · Cited by 3,849 · see citing works

Anorexigenic and Orexigenic Hormone Modulation of Mammalian Target of Rapamycin Complex 1 Activity and the Regulation of Hypothalamic Agouti-Related Protein mRNA Expression

Watterson, K. R., Bestow, D., Gallagher, J. R., Hamilton, D. L., Ashford, F. B., Meakin, P. J., & Ashford, M. L. J. (2012) · Neurosignals · doi:10.1159/000334144 · Cited by 3,395 · see citing works

AMPK regulates energy expenditure by modulating NAD+ metabolism and SIRT1 activity

Cantó, C., Gerhart-Hines, Z., Feige, J. N., Lagouge, M., Noriega, L., Milne, J. C., Elliott, P. J., Puigserver, P., & Auwerx, J. (2009) · Nature · doi:10.1038/nature07813 · Cited by 3,300 · see citing works

Adiponectin and Adiponectin Receptors

Kadowaki, T., & Yamauchi, T. (2005) · Endocrine Reviews · doi:10.1210/er.2005-0005 · Cited by 2,634 · see citing works

Phosphorylation of ULK1 (hATG1) by AMP-Activated Protein Kinase Connects Energy Sensing to Mitophagy

Egan, D. F., Shackelford, D. B., Mihaylova, M. M., Gelino, S., Kohnz, R. A., Mair, W., Vasquez, D. S., Joshi, A., Gwinn, D. M., Taylor, R., et al. (2011) · Science · doi:10.1126/science.1196371 · Cited by 2,600 · see citing works

AMP-activated protein kinase (AMPK) action in skeletal muscle via direct phosphorylation of PGC-1α

Jäger, S., Handschin, C., St.-Pierre, J., & Spiegelman, B. M. (2007) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0705070104 · Cited by 2,491 · see citing works

Evidence that metformin exerts its anti-diabetic effects through inhibition of complex 1 of the mitochondrial respiratory chain

OWEN, M. R., DORAN, E., & HALESTRAP, A. P. (2000) · Biochemical Journal · doi:10.1042/bj3480607 · Cited by 2,157 · see citing works

Leptin stimulates fatty-acid oxidation by activating AMP-activated protein kinase

Minokoshi, Y., Kim, Y.-B., Peroni, O. D., Fryer, L. G. D., Müller, C., Carling, D., & Kahn, B. B. (2002) · Nature · doi:10.1038/415339a · Cited by 2,053 · see citing works

AMPK Phosphorylates and Inhibits SREBP Activity to Attenuate Hepatic Steatosis and Atherosclerosis in Diet-Induced Insulin-Resistant Mice

Li, Y., Xu, S., Mihaylova, M. M., Zheng, B., Hou, X., Jiang, B., Park, O., Luo, Z., Lefai, É., Shyy, J. Y.-J., et al. (2011) · Cell Metabolism · doi:10.1016/j.cmet.2011.03.009 · Cited by 1,783 · see citing works

Complexes between the LKB1 tumor suppressor, STRADα/β and MO25α/β are upstream kinases in the AMP-activated protein kinase cascade

Hawley, S. A., Boudeau, J., Reid, J. L., Mustard, K. J., Udd, L., Mäkelä, T. P., Alessi, D. R., & Hardie, D. G. (2003) · Journal of Biology · doi:10.1186/1475-4924-2-28 · Cited by 1,694 · see citing works

AMP-kinase regulates food intake by responding to hormonal and nutrient signals in the hypothalamus

Minokoshi, Y., Alquier, T., Furukawa, N., Kim, Y.-B., Lee, A., Xue, B., Mu, J., Foufelle, F., Ferré, P., Birnbaum, M. J., et al. (2004) · Nature · doi:10.1038/nature02440 · Cited by 1,637 · see citing works

Calmodulin-dependent protein kinase kinase-β is an alternative upstream kinase for AMP-activated protein kinase

Hawley, S. A., Pan, D. A., Mustard, K. J., Ross, L., Bain, J., Edelman, A. M., Frenguelli, B. G., & Hardie, D. G. (2005) · Cell Metabolism · doi:10.1016/j.cmet.2005.05.009 · Cited by 1,589 · see citing works

ULK1 induces autophagy by phosphorylating Beclin-1 and activating Vps34 lipid kinase

Russell, R. C., Tian, Y., Yuan, H.-X., Park, H., Chang, Y.-Y., Kim, J., Kim, H., Neufeld, T. P., Dillin, A., & Guan, K. (2013) · Nature Cell Biology · doi:10.1038/ncb2757 · Cited by 1,543 · see citing works

THE AMP-ACTIVATED/SNF1 PROTEIN KINASE SUBFAMILY: Metabolic Sensors of the Eukaryotic Cell?

Hardie, D. G., Carling, D., & Carlson, M. (1998) · Annual Review of Biochemistry · doi:10.1146/annurev.biochem.67.1.821 · Cited by 1,436 · see citing works

Dimethylbiguanide inhibits cell respiration via an indirect effect targeted on the respiratory chain complex I

El-Mir, M.-Y., Nogueira, V., Fontaine, E., Avéret, N., Rigoulet, M., & Leverve, X. (2000) · Journal of Biological Chemistry · doi:10.1074/jbc.275.1.223 · Cited by 1,399 · see citing works

Ca2+/calmodulin-dependent protein kinase kinase-β acts upstream of AMP-activated protein kinase in mammalian cells

Woods, A., Dickerson, K., Heath, R. B., Hong, S. P., Momcilovic, M., Johnstone, S. R., Carlson, M., & Carling, D. (2005) · Cell Metabolism · doi:10.1016/j.cmet.2005.06.005 · Cited by 1,382 · see citing works

Characterization of the AMP-activated Protein Kinase Kinase from Rat Liver and Identification of Threonine 172 as the Major Site at Which It Phosphorylates AMP-activated Protein Kinase

Hawley, S. A., Davison, M., Woods, A., Davies, S. P., Beri, R. K., Carling, D., & Hardie, D. G. (1996) · Journal of Biological Chemistry · doi:10.1074/jbc.271.44.27879 · Cited by 1,264 · see citing works

Toll-like receptor–induced changes in glycolytic metabolism regulate dendritic cell activation

Krawczyk, C. M., Holowka, T., Sun, J., Blagih, J., Amiel, E., DeBerardinis, R. J., Cross, J. R., Jung, E., Thompson, C. B., Jones, R. G., et al. (2010) · Blood · doi:10.1182/blood-2009-10-249540 · Cited by 1,246 · see citing works

Evolution of jasmonate and salicylate signal crosstalk

Thaler, J. S., Humphrey, P. T., & Whiteman, N. K. (2012) · Trends in Plant Science · doi:10.1016/j.tplants.2012.02.010 · Cited by 1,243 · see citing works

5-Aminoimidazole-4-Carboxamide Ribonucleoside. A Specific Method for Activating AMP-Activated Protein Kinase in Intact Cells?

Corton, J. M., Gillespie, J. G., Hawley, S. A., & Hardie, D. G. (1995) · European Journal of Biochemistry · doi:10.1111/j.1432-1033.1995.tb20498.x · Cited by 1,232 · see citing works

The mechanism of action of aspirin

Vane, J. R., & Botting, R. M. (2003) · Thrombosis Research · doi:10.1016/s0049-3848(03)00379-7 · Cited by 1,225 · see citing works

AMPK and PPARδ Agonists Are Exercise Mimetics

Narkar, V. A., Downes, M., Yu, R. T., Embler, E., Wang, Y.-X., Banayo, E., Mihaylova, M. M., Nelson, M. C., Zou, Y., Juguilon, H., et al. (2008) · Cell · doi:10.1016/j.cell.2008.06.051 · Cited by 1,222 · see citing works

Metformin Inhibits Hepatic Gluconeogenesis in Mice Independently of the LKB1/AMPK Pathway via a Decrease in Hepatic Energy State

Foretz, M., Hébrard, S., Leclerc, J., Zarrinpashneh, E., Soty, M., Mithieux, G., Sakamoto, K., Andreelli, F., & Viollet, B. (2010) · Journal of Clinical Investigation · doi:10.1172/jci40671 · Cited by 1,181 · see citing works

Metabolism of Inflammation Limited by AMPK and Pseudo-Starvation

O'Neill, L. A. J., & Hardie, D. G. (2013) · Nature · doi:10.1038/nature11862 · Cited by 1,133 · see citing works

Berberine, a Natural Plant Product, Activates AMP-Activated Protein Kinase With Beneficial Metabolic Effects in Diabetic and Insulin-Resistant States

Lee, Y. S., Kim, W. S., Kim, K. H., Yoon, M. J., Cho, H. J., Shen, Y., Ye, J.-M., Lee, C. H., Oh, W. K., Kim, C. T., et al. (2006) · Diabetes · doi:10.2337/db06-0006 · Cited by 1,054 · see citing works

Genome sequence and gene compaction of the eukaryote parasite Encephalitozoon cuniculi

Katinka, M., Duprat, S., Cornillot, E., Méténier, G., Thomarat, F., Prensier, G., Barbe, V., Peyretaillade, E., Brottier, P., Wincker, P., et al. (2001) · Nature · doi:10.1038/35106579 · Cited by 1,051 · see citing works

AICA riboside increases AMP-activated protein kinase, fatty acid oxidation, and glucose uptake in rat muscle

Merrill, G. F., Kurth, E. J., Hardie, D. G., & Winder, W. W. (1997) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.1997.273.6.e1107 · Cited by 1,048 · see citing works

AMP kinase is required for mitochondrial biogenesis in skeletal muscle in response to chronic energy deprivation

Zong, H., Ren, J. M., Young, L. H., Pypaert, M., Mu, J., Birnbaum, M. J., & Shulman, G. I. (2002) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.252625599 · Cited by 1,036 · see citing works

The CREB coactivator TORC2 is a key regulator of fasting glucose metabolism

Koo, S., Flechner, L., Qi, L., Zhang, X., Screaton, R. A., Jeffries, S., Hedrick, S. A., Xu, W., Boussouar, F., Brindle, P. K., et al. (2005) · Nature · doi:10.1038/nature03967 · Cited by 1,025 · see citing works

Acetylation of prostaglandin synthase by aspirin.

Roth, G. J., Stanford, N., & Majerus, P. W. (1975) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.72.8.3073 · Cited by 1,012 · see citing works

The Ca2+/Calmodulin-dependent Protein Kinase Kinases Are AMP-activated Protein Kinase Kinases

Hurley, R. L., Anderson, K. A., Franzone, J. M., Kemp, B. E., Means, A. R., & Witters, L. A. (2005) · Journal of Biological Chemistry · doi:10.1074/jbc.m503824200 · Cited by 1,004 · see citing works

Structure of mammalian AMPK and its regulation by ADP

Xiao, B., Sanders, M. J., Underwood, E., Heath, R., Mayer, F. V., Carmena, D., Jing, C., Walker, P. A., Eccleston, J. F., Haire, L. F., et al. (2011) · Nature · doi:10.1038/nature09932 · Cited by 926 · see citing works

A Role for AMP-Activated Protein Kinase in Contraction- and Hypoxia-Regulated Glucose Transport in Skeletal Muscle

Mu, J., Brozinick, J. T., Valladares, O., Bucan, M., & Birnbaum, M. J. (2001) · Molecular Cell · doi:10.1016/s1097-2765(01)00251-9 · Cited by 924 · see citing works

Single phosphorylation sites in Acc1 and Acc2 regulate lipid homeostasis and the insulin-sensitizing effects of metformin

Fullerton, M. D., Galic, S., Marcinko, K., Sikkema, S., Pulinilkunnil, T., Chen, Z.-P., O'Neill, H. M., Ford, R. J., Palanivel, R., O'Brien, M., et al. (2013) · Nature Medicine · doi:10.1038/nm.3372 · Cited by 893 · see citing works

Phosphorylation and activation of heart PFK-2 by AMPK has a role in the stimulation of glycolysis during ischaemia

Marsin, A.-S., Bertrand, L., Rider, M. H., Deprez, J., Beauloye, C., Vincent, M. F., den Berghe, G. V., Carling, D., & Hue, L. (2000) · Current Biology · doi:10.1016/s0960-9822(00)00742-9 · Cited by 853 · see citing works

Biguanides suppress hepatic glucagon signalling by decreasing production of cyclic AMP

Miller, R., Chu, Q., Xie, J., Foretz, M., Viollet, B., & Birnbaum, M. J. (2013) · Nature · doi:10.1038/nature11808 · Cited by 845 · see citing works

Adiponectin Stimulates AMP-Activated Protein Kinase in the Hypothalamus and Increases Food Intake

Kubota, N., Yano, W., Kubota, T., Yamauchi, T., Itoh, S., Kumagai, H., Kozono, H., Takamoto, I., Okamoto, S., Shiuchi, T., et al. (2007) · Cell Metabolism · doi:10.1016/j.cmet.2007.06.003 · Cited by 844 · see citing works

Differential Regulation of Distinct Vps34 Complexes by AMPK in Nutrient Stress and Autophagy

Kim, J., Kim, Y. C., Fang, C., Russell, R. C., Kim, J. H., Fan, W., Liu, R., Zhong, Q., & Guan, K. (2013) · Cell · doi:10.1016/j.cell.2012.12.016 · Cited by 799 · see citing works

Inactivation of acetyl-CoA carboxylase and activation of AMP-activated protein kinase in muscle during exercise

Winder, W. W., & Hardie, D. G. (1996) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.1996.270.2.e299 · Cited by 799 · see citing works

Adenosine 5′-Monophosphate-Activated Protein Kinase Promotes Macrophage Polarization to an Anti-Inflammatory Functional Phenotype

Sağ, D., Carling, D., Stout, R. D., & Suttles, J. (2008) · The Journal of Immunology · doi:10.4049/jimmunol.181.12.8633 · Cited by 798 · see citing works

AMP‐activated protein kinase: the energy charge hypothesis revisited

Hardie, D. G., & Hawley, S. A. (2001) · BioEssays · doi:10.1002/bies.10009 · Cited by 794 · see citing works

Use of Cells Expressing γ Subunit Variants to Identify Diverse Mechanisms of AMPK Activation

Hawley, S. A., Ross, F. A., Chevtzoff, C., Green, K. A., Evans, A., Fogarty, S., Towler, M. C., Brown, L. J., Ogunbayo, O. A., Evans, A. M., et al. (2010) · Cell Metabolism · doi:10.1016/j.cmet.2010.04.001 · Cited by 773 · see citing works

The Ancient Drug Salicylate Directly Activates AMP-Activated Protein Kinase

Hawley, S. A., Fullerton, M. D., Ross, F. A., Schertzer, J. D., Chevtzoff, C., Walker, K. J., Peggie, M. W., Zibrova, D., Green, K. A., Mustard, K. J., et al. (2012) · Science · doi:10.1126/science.1215327 · Cited by 760 · see citing works

CBS domains form energy-sensing modules whose binding of adenosine ligands is disrupted by disease mutations

Scott, J. W., Hawley, S. A., Green, K. A., Anis, M., Stewart, G., Scullion, G. A., Norman, D. G., & Hardie, D. G. (2004) · Journal of Clinical Investigation · doi:10.1172/jci19874 · Cited by 754 · see citing works

5' AMP-activated protein kinase activation causes GLUT4 translocation in skeletal muscle.

Kurth-Kraczek, E. J., Hirshman, M. F., Goodyear, L. J., & Winder, W. W. (1999) · Diabetes · doi:10.2337/diabetes.48.8.1667 · Cited by 715 · see citing works

Hypothalamic AMPK and fatty acid metabolism mediate thyroid regulation of energy balance

López, M., Varela, L., Vazquez, M. J., Rodríguez‐Cuenca, S., González, C. R., Velagapudi, V., Morgan, D. A., Schoenmakers, E., Agassandian, K., Lage, R., et al. (2010) · Nature Medicine · doi:10.1038/nm.2207 · Cited by 686 · see citing works

AMPK-Dependent Degradation of TXNIP upon Energy Stress Leads to Enhanced Glucose Uptake via GLUT1

Wu, N., Zheng, B., Shaywitz, A. J., Dagon, Y., Tower, C., Bellinger, G., Shen, C., Wen, J., Asara, J. M., McGraw, T. E., et al. (2013) · Molecular Cell · doi:10.1016/j.molcel.2013.01.035 · Cited by 665 · see citing works

The AMP-activated protein kinase AAK-2 links energy levels and insulin-like signals to lifespan in <i>C. elegans</i>

Apfeld, J., O'Connor, G., McDonagh, T., DiStefano, P. S., & Curtis, R. (2004) · Genes &amp; Development · doi:10.1101/gad.1255404 · Cited by 643 · see citing works

Role of AMP-activated protein kinase in mechanism of metformin action

Zhou, G., Myers, R., Li, Y., et al. (2001) · Journal of Clinical Investigation · doi:10.1172/jci200113505 · Cited by 635 · see citing works

AMPK is a direct adenylate charge-regulated protein kinase

Oakhill, J. S., Steel, R., Chen, Z.-P., Scott, J. W., Ling, N., Tam, S., & Kemp, B. E. (2011) · Science · doi:10.1126/science.1200094 · Cited by 612 · see citing works

Co-Localization of Growth Hormone Secretagogue Receptor and NPY mRNA in the Arcuate Nucleus of the Rat

Willesen, M. G., Kristensen, P., & Rømer, J. (1999) · Neuroendocrinology · doi:10.1159/000054491 · Cited by 605 · see citing works

A common bicyclic protein kinase cascade inactivates the regulatory enzymes of fatty acid and cholesterol biosynthesis

Carling, D., Zammit, V. A., & Hardie, D. G. (1987) · FEBS Letters · doi:10.1016/0014-5793(87)80292-2 · Cited by 599 · see citing works

5′‐AMP inhibits dephosphorylation, as well as promoting phosphorylation, of the AMP‐activated protein kinase. Studies using bacterially expressed human protein phosphatase‐2C <i>α</i> and native bovine protein phosphatase‐2A _c

(1995) · FEBS Letters · doi:10.1016/0014-5793(95)01368-7 · Cited by 595 · see citing works

Structural basis for AMP binding to mammalian AMP-activated protein kinase

Xiao, B., Heath, R., Saiu, P., Leiper, F. C., Leone, P., Jing, C., Walker, P. A., Haire, L., Eccleston, J. F., Davis, C. T., et al. (2007) · Nature · doi:10.1038/nature06161 · Cited by 591 · see citing works

Class IIa Histone Deacetylases Are Hormone-Activated Regulators of FOXO and Mammalian Glucose Homeostasis

Mihaylova, M. M., Vasquez, D. S., Ravnskjær, K., Denechaud, P., Yu, R. T., Alvarez, J. G. A., Downes, M., Evans, R. M., Montminy, M., & Shaw, R. J. (2011) · Cell · doi:10.1016/j.cell.2011.03.043 · Cited by 578 · see citing works

Different dietary restriction regimens extend lifespan by both independent and overlapping genetic pathways in C. elegans

Greer, E. L., & Brunet, A. (2009) · Aging Cell · doi:10.1111/j.1474-9726.2009.00459.x · Cited by 574 · see citing works

Structural basis of AMPK regulation by small molecule activators

Xiao, B., Sanders, M. J., Carmena, D., Bright, N. J., Haire, L. F., Underwood, E., Patel, B. R., Heath, R. B., Walker, P. A., Hallén, S., et al. (2013) · Nature Communications · doi:10.1038/ncomms4017 · Cited by 566 · see citing works

High Rates of Fatty Acid Oxidation during Reperfusion of Ischemic Hearts Are Associated with a Decrease in Malonyl-CoA Levels Due to an Increase in 5’-AMP-activated Protein Kinase Inhibition of Acetyl-CoA Carboxylase

Kudo, N., Barr, A., Barr, R. L., Desai, S. S., & Lopaschuk, G. D. (1995) · Journal of Biological Chemistry · doi:10.1074/jbc.270.29.17513 · Cited by 565 · see citing works

Knockout of the α2 but Not α1 5′-AMP-activated Protein Kinase Isoform Abolishes 5-Aminoimidazole-4-carboxamide-1-β-4-ribofuranosidebut Not Contraction-induced Glucose Uptake in Skeletal Muscle

Jørgensen, S. B., Viollet, B., Andreelli, F., Frøsig, C., Birk, J. B., Schjerling, P., Vaulont, S., Richter, E. A., & Wojtaszewski, J. F. P. (2004) · Journal of Biological Chemistry · doi:10.1074/jbc.m306205200 · Cited by 553 · see citing works

Deficiency of LKB1 in skeletal muscle prevents AMPK activation and glucose uptake during contraction

Sakamoto, K., McCarthy, A., Smith, D. P., Green, K. A., Hardie, D. G., Ashworth, A., & Alessi, D. R. (2005) · The EMBO Journal · doi:10.1038/sj.emboj.7600667 · Cited by 538 · see citing works

AMP Is a True Physiological Regulator of AMP-Activated Protein Kinase by Both Allosteric Activation and Enhancing Net Phosphorylation

Gowans, G. J., Hawley, S. A., Ross, F. A., & Hardie, D. G. (2013) · Cell Metabolism · doi:10.1016/j.cmet.2013.08.019 · Cited by 531 · see citing works

Thiazolidinediones, Like Metformin, Inhibit Respiratory Complex I

Brunmair, B., Staniek, K., Gras, F., Scharf, N., Althaym, A., Clara, R., Roden, M., Gnaiger, E., Nohl, H., Waldhäusl, W., et al. (2004) · Diabetes · doi:10.2337/diabetes.53.4.1052 · Cited by 521 · see citing works

AMPK is essential for energy homeostasis regulation and glucose sensing by POMC and AgRP neurons

Claret, M., Smith, M. A., Batterham, R. L., Selman, C., Choudhury, A. I., Fryer, L. G. D., Clements, M., Al‐Qassab, H., Heffron, H., Xu, A. W., et al. (2007) · Journal of Clinical Investigation · doi:10.1172/jci31516 · Cited by 506 · see citing works

Diacylglycerol-mediated insulin resistance

Erion, D. M., & Shulman, G. I. (2010) · Nature Medicine · doi:10.1038/nm0410-400 · Cited by 502 · see citing works

Chronic activation of 5′-AMP-activated protein kinase increases GLUT-4, hexokinase, and glycogen in muscle

Holmes, B. F., Kurth-Kraczek, E. J., & Winder, W. W. (1999) · Journal of Applied Physiology · doi:10.1152/jappl.1999.87.5.1990 · Cited by 489 · see citing works

AMPK: A Target for Drugs and Natural Products With Effects on Both Diabetes and Cancer

Hardie, D. G. (2013) · Diabetes · doi:10.2337/db13-0368 · Cited by 458 · see citing works

AMP-activated protein kinase regulates GLUT4 transcription by phosphorylating histone deacetylase 5

McGee, S. L., van Denderen, B. J. W., Howlett, K. F., Mollica, J., Schertzer, J. D., Kemp, B. E., & Hargreaves, M. (2008) · Diabetes · doi:10.2337/db07-0843 · Cited by 455 · see citing works

Berberine suppresses proinflammatory responses through AMPK activation in macrophages

Jeong, H. W., Hsu, K. C., Lee, J.-W., Ham, M., Huh, J. Y., Shin, H. J., Kim, W. S., & Kim, J. B. (2009) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.90599.2008 · Cited by 454 · see citing works

Involvement of organic cation transporter 1 in hepatic and intestinal distribution of metformin

Wang, D.-S., Jonker, J. W., Kato, Y., Kusuhara, H., Schinkel, A. H., & Sugiyama, Y. (2002) · The Journal of Pharmacology and Experimental Therapeutics · doi:10.1124/jpet.102.034140 · Cited by 441 · see citing works

Hunger States Switch a Flip-Flop Memory Circuit via a Synaptic AMPK-Dependent Positive Feedback Loop

Yang, Y., Atasoy, D., Su, H. H., & Sternson, S. M. (2011) · Cell · doi:10.1016/j.cell.2011.07.039 · Cited by 431 · see citing works

AMP-activated kinase reciprocally regulates triacylglycerol synthesis and fatty acid oxidation in liver and muscle: evidence that sn-glycerol-3-phosphate acyltransferase is a novel target

Muoio, D. M., Seefeld, K. J., Witters, L. A., & Coleman, R. (1999) · Biochemical Journal · doi:10.1042/bj3380783 · Cited by 429 · see citing works

AMP-activated protein kinase: nature's energy sensor

Carling, D., Mayer, F. V., Sanders, M. J., & Gamblin, S. J. (2011) · Nature Chemical Biology · doi:10.1038/nchembio.610 · Cited by 425 · see citing works

Macrophage α1 AMP-activated Protein Kinase (α1AMPK) Antagonizes Fatty Acid-induced Inflammation through SIRT1

Yang, Z., Kahn, B. B., Shi, H., & Xue, B. (2010) · Journal of Biological Chemistry · doi:10.1074/jbc.m110.123620 · Cited by 417 · see citing works

AMP-activated protein kinase is activated by low glucose in cell lines derived from pancreatic β cells, and may regulate insulin release

Salt, I. P., JOHNSON, G., Ashcroft, S. J. H., & Hardie, D. G. (1998) · Biochemical Journal · doi:10.1042/bj3350533 · Cited by 408 · see citing works

AMP-activated protein kinase (AMPK) β1β2 muscle null mice reveal an essential role for AMPK in maintaining mitochondrial content and glucose uptake during exercise

O'Neill, H. M., Maarbjerg, S. J., Crane, J. D., Jeppesen, J., Jørgensen, S. B., Schertzer, J. D., Shyroka, O., Kiens, B., van Denderen, B. J., Tarnopolsky, M. A., et al. (2011) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1105062108 · Cited by 406 · see citing works

Hypothalamic CaMKK2 Contributes to the Regulation of Energy Balance

Anderson, K. A., Ribar, T. J., Lin, F., Noeldner, P. K., Green, M. F., Muehlbauer, M. J., Witters, L. A., Kemp, B. E., & Means, A. R. (2008) · Cell Metabolism · doi:10.1016/j.cmet.2008.02.011 · Cited by 385 · see citing works

The Stimulation of Glycolysis by Hypoxia in Activated Monocytes Is Mediated by AMP-activated Protein Kinase and Inducible 6-Phosphofructo-2-kinase

Marsin, A.-S., Bouzin, C., Bertrand, L., & Hue, L. (2002) · Journal of Biological Chemistry · doi:10.1074/jbc.m205213200 · Cited by 380 · see citing works

M <scp>USCLE</scp> T <scp>RIGLYCERIDE AND</scp> I <scp>NSULIN</scp> R <scp>ESISTANCE</scp>

Kelley, D. E., Goodpaster, B. H., & Storlien, L. (2002) · Annual Review of Nutrition · doi:10.1146/annurev.nutr.22.010402.102912 · Cited by 364 · see citing works

Insulin Antagonizes Ischemia-induced Thr172 Phosphorylation of AMP-activated Protein Kinase α-Subunits in Heart via Hierarchical Phosphorylation of Ser485/491

Horman, S., Vertommen, D., Heath, R. B., Neumann, D., Mouton, V., Woods, A., Schlattner, U., Wallimann, T., Carling, D., Hue, L., et al. (2005) · Journal of Biological Chemistry · doi:10.1074/jbc.m506850200 · Cited by 355 · see citing works

Stimulation of the AMP-activated protein kinase leads to activation of eukaryotic elongation factor 2 kinase and to its phosphorylation at a novel site, serine 398

Browne, G. J., Finn, S. G., & Proud, C. G. (2004) · Journal of Biological Chemistry · doi:10.1074/jbc.m309773200 · Cited by 353 · see citing works

Regulation of Hepatic Acetyl Coenzyme A Carboxylase by Phosphorylation and Dephosphorylation

Carlson, C. A., & Kim, K.-H. (1973) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)44486-4 · Cited by 346 · see citing works

Mammalian AMP-activated protein kinase shares structural and functional homology with the catalytic domain of yeast Snf1 protein kinase.

Mitchelhill, K. I., Stapleton, D., Gao, G., House, C. M., Michell, B. J., Katsis, F., Witters, L. A., & Kemp, B. E. (1994) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(17)41951-x · Cited by 338 · see citing works

Anti-lipolytic Action of AMP-activated Protein Kinase in Rodent Adipocytes

Daval, M., DUPUY, F., Bazin, R., Hainault, I., Viollet, B., Vaulont, S., Hajduch, É., Ferré, P., & Foufelle, F. (2005) · Journal of Biological Chemistry · doi:10.1074/jbc.m414222200 · Cited by 323 · see citing works

Modulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase activity with cAMP and with protein fractions of rat liver cytosol

Beg, Z. H., Allmann, D. W., & Gibson, D. M. (1973) · Biochemical and Biophysical Research Communications · doi:10.1016/0006-291x(73)91137-6 · Cited by 315 · see citing works

Identification by amino acid sequencing of three major regulatory phosphorylation sites on rat acetyl-CoA carboxylase

MUNDAY, M. R., CAMPBELL, D. G., CARLING, D., & HARDIE, D. G. (1988) · European Journal of Biochemistry · doi:10.1111/j.1432-1033.1988.tb14201.x · Cited by 308 · see citing works

Antagonistic Controls of Autophagy and Glycogen Accumulation by Snf1p, the Yeast Homolog of AMP-Activated Protein Kinase, and the Cyclin-Dependent Kinase Pho85p

Wang, Z., Wilson, W. A., Fujino, M., & Roach, P. J. (2001) · Molecular and Cellular Biology · doi:10.1128/mcb.21.17.5742-5752.2001 · Cited by 300 · see citing works

Activity of LKB1 and AMPK-related kinases in skeletal muscle: effects of contraction, phenformin, and AICAR

Sakamoto, K., Göransson, O., Hardie, D. G., & Alessi, D. R. (2004) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00074.2004 · Cited by 299 · see citing works

p70S6 Kinase Phosphorylates AMPK on Serine 491 to Mediate Leptin's Effect on Food Intake

Dagon, Y., Hur, E. E., Zheng, B., Wellenstein, K., Cantley, L. C., & Kahn, B. B. (2012) · Cell Metabolism · doi:10.1016/j.cmet.2012.05.010 · Cited by 297 · see citing works

Location and function of three sites phosphorylated on rat acetyl-CoA carboxylase by the AMP-activated protein kinase

DAVIES, S. P., SIM, A. T. R., & HARDIE, D. G. (1990) · European Journal of Biochemistry · doi:10.1111/j.1432-1033.1990.tb15293.x · Cited by 274 · see citing works

Phosphorylation of bovine hormone‐sensitive lipase by the AMP‐activated protein kinase

Garton, A. J., Campbell, D. G., Carling, D., Hardie, D. G., Colbran, R. J., & Yeaman, S. J. (1989) · European Journal of Biochemistry · doi:10.1111/j.1432-1033.1989.tb14548.x · Cited by 271 · see citing works

A novel route for ATP acquisition by the remnant mitochondria of Encephalitozoon cuniculi

Tsaousis, A. D., Kunji, E. R. S., Goldberg, A. V., Lucocq, J. M., Hirt, R. P., & Embley, T. M. (2008) · Nature · doi:10.1038/nature06903 · Cited by 269 · see citing works

AMP as a Low-Energy Charge Signal Autonomously Initiates Assembly of AXIN-AMPK-LKB1 Complex for AMPK Activation

Zhang, Y., Guo, H., Zhang, C., Lin, S., Yin, Z., Peng, Y., Luo, H., Shi, Y., Lian, G., Zhang, C., et al. (2013) · Cell Metabolism · doi:10.1016/j.cmet.2013.09.005 · Cited by 266 · see citing works

Method for the Quantitative Extraction of Resveratrol and Piceid Isomers in Grape Berry Skins. Effect of Powdery Mildew on the Stilbene Content

Romero‐Pérez, A. I., Lamuela-Raventós, R. M., Andrés‐Lacueva, C., & de la Torre-Boronat, M. C. (2000) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf000745o · Cited by 245 · see citing works

The α2–5′AMP-Activated Protein Kinase Is a Site 2 Glycogen Synthase Kinase in Skeletal Muscle and Is Responsive to Glucose Loading

Jørgensen, S. B., Nielsen, J. N., Birk, J. B., Olsen, G. S., Viollet, B., Andreelli, F., Schjerling, P., Vaulont, S., Hardie, D. G., Hansen, B. F., et al. (2004) · Diabetes · doi:10.2337/diabetes.53.12.3074 · Cited by 241 · see citing works

Phosphorylation by Akt within the ST loop of AMPK-α1 down-regulates its activation in tumour cells

Hawley, S. A., Ross, F. A., Gowans, G. J., Tibarewal, P., Leslie, N. R., & Hardie, D. G. (2014) · Biochemical Journal · doi:10.1042/bj20131344 · Cited by 229 · see citing works

AMP-activated protein kinase adapts rRNA synthesis to cellular energy supply

Hoppe, S., Bierhoff, H., Cado, I., Weber, A., Tiebe, M., Grummt, I., & Voit, R. (2009) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0909873106 · Cited by 225 · see citing works

Pharmacokinetics of aspirin and salicylate in relation to inhibition of arachidonate cyclooxygenase and antiinflammatory activity.

Higgs, G. A., Salmon, J. A., Henderson, B. E., & Vane, J. R. (1987) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.84.5.1417 · Cited by 222 · see citing works

Inhibition by AICA Riboside of Gluconeogenesis in Isolated Rat Hepatocytes

Vincent, M., Marangos, P. J., Gruber, H. E., & Berghe, G. (1991) · Diabetes · doi:10.2337/diab.40.10.1259 · Cited by 218 · see citing works

Naringin ameliorates metabolic syndrome by activating AMP-activated protein kinase in mice fed a high-fat diet

Pu, P., Gao, D.-M., Salim, M., Chen, J., Zhang, J., Zhou, X., Nai-jing, Z., Xie, J., & Jiang, H. (2011) · Archives of Biochemistry and Biophysics · doi:10.1016/j.abb.2011.11.026 · Cited by 203 · see citing works

AMPK functions as an adenylate charge-regulated protein kinase

Oakhill, J. S., Scott, J. W., & Kemp, B. E. (2012) · Trends in Endocrinology and Metabolism · doi:10.1016/j.tem.2011.12.006 · Cited by 201 · see citing works

Characterization of the role of the AMP-activated protein kinase in the stimulation of glucose transport in skeletal muscle cells

Fryer, L. G. D., Foufelle, F., Barnes, K., Baldwin, S. A., Woods, A., & Carling, D. (2002) · Biochemical Journal · doi:10.1042/0264-6021:3630167 · Cited by 198 · see citing works

μ-Opioid Receptor Activates Signaling Pathways Implicated in Cell Survival and Translational Control

Polakiewicz, R. D., Schieferl, S. M., Gingras, A., Sonenberg, N., & Comb, M. J. (1998) · Journal of Biological Chemistry · doi:10.1074/jbc.273.36.23534 · Cited by 189 · see citing works

Salicylates and sulfasalazine, but not glucocorticoids, inhibit leukocyte accumulation by an adenosine-dependent mechanism that is independent of inhibition of prostaglandin synthesis and p105 of NFκB

Cronstein, B. N., Montesinos, M. C., & Weissmann, G. (1999) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.96.11.6377 · Cited by 183 · see citing works

Crystal Structures of the Adenylate Sensor from Fission Yeast AMP-Activated Protein Kinase

Townley, R. A., & Shapiro, L. S. (2007) · Science · doi:10.1126/science.1137503 · Cited by 181 · see citing works

Physiological role of AMP-activated protein kinase in the heart: graded activation during exercise

Coven, D. L., Hu, X., Cong, L., Bergeron, R., Shulman, G. I., Hardie, D. G., & Young, L. H. (2003) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00171.2003 · Cited by 174 · see citing works

Purification of the AMP‐activated protein kinase on ATP‐γ‐Sepharose and analysis of its subunit structure

DAVIES, S. P., Hawley, S. A., Woods, A., Carling, D., Haystead, T., & Hardie, D. G. (1994) · European Journal of Biochemistry · doi:10.1111/j.1432-1033.1994.tb19001.x · Cited by 173 · see citing works

Key Role for AMP-Activated Protein Kinase in the Ventromedial Hypothalamus in Regulating Counterregulatory Hormone Responses to Acute Hypoglycemia

McCrimmon, R. J., Shaw, M., Fan, X., Cheng, H. M., Ding, Y., Vella, M. C., Zhou, L., McNay, E. C., & Sherwin, R. S. (2007) · Diabetes · doi:10.2337/db07-0837 · Cited by 172 · see citing works

Genetic disruption of AMPK signaling abolishes both contraction- and insulin-stimulated TBC1D1 phosphorylation and 14-3-3 binding in mouse skeletal muscle

Pehmøller, C., Treebak, J. T., Birk, J. B., Chen, S., MacKintosh, C., Hardie, D. G., Richter, E. A., & Wojtaszewski, J. F. P. (2009) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00115.2009 · Cited by 171 · see citing works

ADP Regulates SNF1, the Saccharomyces cerevisiae Homolog of AMP-Activated Protein Kinase

Mayer, F. V., Heath, R. B., Underwood, E., Sanders, M. J., Carmena, D., McCartney, R. R., Leiper, F. C., Xiao, B., Jing, C., Walker, P. A., et al. (2011) · Cell Metabolism · doi:10.1016/j.cmet.2011.09.009 · Cited by 169 · see citing works

Crystal structure of the heterotrimer core of Saccharomyces cerevisiae AMPK homologue SNF1

Amodeo, G. A., Rudolph, M. J., & Tong, L. (2007) · Nature · doi:10.1038/nature06127 · Cited by 164 · see citing works

Purple sweet potato anthocyanins attenuate hepatic lipid accumulation through activating adenosine monophosphate–activated protein kinase in human HepG2 cells and obese mice

Hwang, Y. P., Choi, J. H., Han, E. H., Kim, H. G., Wee, J., Jung, K. O., Jung, K. H., Kwon, K., Jeong, T. C., Chung, Y., et al. (2011) · Nutrition Research · doi:10.1016/j.nutres.2011.09.026 · Cited by 160 · see citing works

Fatal Congenital Heart Glycogenosis Caused by a Recurrent Activating R531Q Mutation in the γ2-Subunit of AMP-Activated Protein Kinase (PRKAG2), Not by Phosphorylase Kinase Deficiency

Burwinkel, B., Scott, J. W., Bührer, C., van Landeghem, F. K. H., Cox, G. F., Wilson, C. J., Hardie, D. G., & Kilimann, M. W. (2005) · The American Journal of Human Genetics · doi:10.1086/430840 · Cited by 155 · see citing works

Snf1‐related protein kinase 1 is needed for growth in a normal day–night light cycle

Thelander, M., Olsson, T., & Ronne, H. (2004) · The EMBO Journal · doi:10.1038/sj.emboj.7600182 · Cited by 155 · see citing works

Regulation of rat liver acetyl-CoA carboxylase. Regulation of phosphorylation and inactivation of acetyl-CoA carboxylase by the adenylate energy charge.

Yeh, L.-A., Lee, K. H., & Kim, K. H. (1980) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)85891-x · Cited by 153 · see citing works

Transport and accumulation of flavonoids in grapevine (Vitis viniferaL.)

Braidot, E., Zancani, M., Petrussa, E., et al. (2008) · Plant Signaling & Behavior · doi:10.4161/psb.3.9.6686 · Cited by 151 · see citing works

Calmodulin-dependent protein kinase kinase-β activates AMPK without forming a stable complex: synergistic effects of Ca2+ and AMP

Fogarty, S., Hawley, S. A., Green, K. A., Saner, N., Mustard, K. J., & Hardie, D. G. (2009) · Biochemical Journal · doi:10.1042/bj20091372 · Cited by 146 · see citing works

Reversible modulation of the activities of both liver microsomal hydroxymethylglutaryl coenzyme a reductase and its inactivating enzyme. Evidence for regulation by phosphorylation-dephosphorylation

Ingebritsen, T. S., Lee, H.-S., Parker, R. A., et al. (1978) · Biochemical and Biophysical Research Communications · doi:10.1016/0006-291x(78)91273-1 · Cited by 144 · see citing works

NPY/AgRP neurons are not essential for feeding responses to glucoprivation

Luquet, S. H., Phillips, C. T., & Palmiter, R. D. (2006) · Peptides · doi:10.1016/j.peptides.2006.08.036 · Cited by 141 · see citing works

Antiadipogenic Effect of Dietary Apigenin through Activation of AMPK in 3T3-L1 Cells

Ono, M., & Fujimori, K. (2011) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf203490a · Cited by 139 · see citing works

Tangeretin stimulates glucose uptake via regulation of AMPK signaling pathways in C2C12 myotubes and improves glucose tolerance in high-fat diet-induced obese mice

Kim, M., Hur, H. J., Kwon, D. Y., & Hwang, J. (2012) · Molecular and Cellular Endocrinology · doi:10.1016/j.mce.2012.03.013 · Cited by 138 · see citing works

AMP-activated protein kinase undergoes nucleotide-dependent conformational changes

Chen, L., Wang, J., Zhang, Y., Yan, S. F., Neumann, D., Schlattner, U., Wang, Z., & Wu, J. (2012) · Nature Structural & Molecular Biology · doi:10.1038/nsmb.2319 · Cited by 137 · see citing works

AMP-activated protein kinase phosphorylates and inactivates liver glycogen synthase

Bultot, L., Guigas, B., Von Wilamowitz-Moellendorff, A., Maisin, L., Vertommen, D., Hussain, N., Beullens, M., Guinovart, J. J., Foretz, M., Viollet, B., et al. (2012) · Biochemical Journal · doi:10.1042/bj20112026 · Cited by 131 · see citing works

Tiliroside, a glycosidic flavonoid, ameliorates obesity-induced metabolic disorders via activation of adiponectin signaling followed by enhancement of fatty acid oxidation in liver and skeletal muscle in obese–diabetic mice

Goto, T., Teraminami, A., Lee, J.-Y., Ohyama, K., Funakoshi, K., Kim, Y.-I., Hirai, S., Uemura, T., Yu, R., Takahashi, N., et al. (2011) · The Journal of Nutritional Biochemistry · doi:10.1016/j.jnutbio.2011.04.001 · Cited by 128 · see citing works

Rhodiola rosea extracts and salidroside decrease the growth of bladder cancer cell lines via inhibition of the mTOR pathway and induction of autophagy

Liu, Z., Li, X., Simoneau, A. R., Jafari, M., & Zi, X. (2011) · Molecular Carcinogenesis · doi:10.1002/mc.20780 · Cited by 119 · see citing works

Mangiferin decreases plasma free fatty acids through promoting its catabolism in liver by activation of AMPK

Niu, Y., Li, S., Na, L., Feng, R., Liu, L., Li, Y., & Sun, C. (2012) · PLoS ONE · doi:10.1371/journal.pone.0030782 · Cited by 116 · see citing works

Ursolic acid-induced AMP-activated protein kinase (AMPK) activation contributes to growth inhibition and apoptosis in human bladder cancer T24 cells

Zheng, Q.-Y., Jin, F.-S., Yao, C., Zhang, T., Zhang, G., & Ai, X. (2012) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2012.02.093 · Cited by 112 · see citing works

Aspalathin improves hyperglycemia and glucose intolerance in obese diabetic ob/ob mice

Son, M. J., Minakawa, M., Miura, Y., & Yagasaki, K. (2012) · European Journal of Nutrition · doi:10.1007/s00394-012-0466-6 · Cited by 111 · see citing works

Novel epigallocatechin gallate (EGCG) analogs activate AMP-activated protein kinase pathway and target cancer stem cells

Chen, D., Pamu, S., Cui, Q. C., Chan, T. H., & Dou, Q. P. (2012) · Bioorganic & Medicinal Chemistry · doi:10.1016/j.bmc.2012.03.002 · Cited by 106 · see citing works

Arctigenin, a natural compound, activates AMP-activated protein kinase via inhibition of mitochondria complex I and ameliorates metabolic disorders in ob/ob mice

Huang, S., Yu, R.-T., Gong, J., Feng, Y., Dai, Y.-L., Hu, F., Hu, Y., Tao, Y.-D., & Leng, Y. (2011) · Diabetologia · doi:10.1007/s00125-011-2366-3 · Cited by 104 · see citing works

Crucial role for LKB1 to AMPKα2 axis in the regulation of CD36-mediated long-chain fatty acid uptake into cardiomyocytes☆

Habets, D. D. J., Coumans, W. A., Hasnaoui, M. E., Zarrinpashneh, E., Bertrand, L., Viollet, B., Kiens, B., Jensen, T. E., Richter, E. A., & Bonen, A. (2008) · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids · doi:10.1016/j.bbalip.2008.12.009 · Cited by 103 · see citing works

Xanthigen Suppresses Preadipocyte Differentiation and Adipogenesis through Down-regulation of PPARγ and C/EBPs and Modulation of SIRT-1, AMPK, and FoxO Pathways

Lai, C., Tsai, M.-L., Badmaev, V., Jimenez, M., Ho, C., & Pan, M. (2012) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf204862d · Cited by 102 · see citing works

AMPK activation with glabridin ameliorates adiposity and lipid dysregulation in obesity

Lee, J.-W., Choe, S. S., Jang, H., Kim, J., Jeong, H. W., Jo, H., Jeong, K.-H., Tadi, S., Park, M. G., Kwak, T. H., et al. (2012) · Journal of Lipid Research · doi:10.1194/jlr.m022897 · Cited by 102 · see citing works

Pu-erh tea, green tea, and black tea suppresses hyperlipidemia, hyperleptinemia and fatty acid synthase through activating AMPK in rats fed a high-fructose diet

Huang, H., & Lin, J. (2011) · Food & Function · doi:10.1039/c1fo10157a · Cited by 99 · see citing works

Ginsenoside Re lowers blood glucose and lipid levels via activation of AMP-activated protein kinase in HepG2 cells and high-fat diet fed mice

Chung, S. H. (2011) · International Journal of Molecular Medicine · doi:10.3892/ijmm.2011.805 · Cited by 95 · see citing works

Hispidulin Potently Inhibits Human Glioblastoma Multiforme Cells through Activation of AMP-Activated Protein Kinase (AMPK)

Lin, Y., Hung, C., Tsai, J.-C., Lee, J., Chen, Y. S., Wei, C.-W., Kao, J., & Way, T. (2010) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf1019533 · Cited by 94 · see citing works

Activation of AMPK by Pterostilbene Suppresses Lipogenesis and Cell-Cycle Progression in p53 Positive and Negative Human Prostate Cancer Cells

Lin, V. C.-H., Tsai, Y.-C., Lin, J.-N., Fan, L.-L., Pan, M., Ho, C., Wu, J., & Way, T. (2012) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf301499e · Cited by 90 · see citing works

The Snf1 Protein Kinase Controls the Induction of Genes of the Iron Uptake Pathway at the Diauxic Shift in Saccharomyces cerevisiae

Haurie, V., Boucherie, H., & Sagliocco, F. A. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m307447200 · Cited by 87 · see citing works

AMPK: mediating the metabolic effects of salicylate-based drugs?

Steinberg, G. R., Dandapani, M., & Hardie, D. G. (2013) · Trends in Endocrinology and Metabolism · doi:10.1016/j.tem.2013.06.002 · Cited by 85 · see citing works

Coffee polyphenol caffeic acid but not chlorogenic acid increases 5′AMP-activated protein kinase and insulin-independent glucose transport in rat skeletal muscle

Tsuda, S., Egawa, T., Ma, X., Oshima, R., Kurogi, E., & Hayashi, T. (2012) · The Journal of Nutritional Biochemistry · doi:10.1016/j.jnutbio.2011.09.001 · Cited by 84 · see citing works

Geraniol induces cooperative interaction of apoptosis and autophagy to elicit cell death in PC-3 prostate cancer cells

Jeon, J. (2011) · International Journal of Oncology · doi:10.3892/ijo.2011.1318 · Cited by 81 · see citing works

The AMP-regulated kinase family: Enigmatic targets for diabetes therapy

Rutter, G. A., & Leclerc, I. (2008) · Molecular and Cellular Endocrinology · doi:10.1016/j.mce.2008.05.020 · Cited by 75 · see citing works

Comparative analgesic and anti‐inflammatory properties of sodium salicylate and acetylsalicylic acid (aspirin) in rheumatoid arthritis.

Preston, S., Arnold, M. H., Beller, E., Brooks, P., & Buchanan, W. W. (1989) · British Journal of Clinical Pharmacology · doi:10.1111/j.1365-2125.1989.tb03423.x · Cited by 74 · see citing works

The complement of protein kinases of the microsporidium Encephalitozoon cuniculi in relation to those of Saccharomyces cerevisiae and Schizosaccharomyces pombe

Miranda‐Saavedra, D., Stark, M. J. R., Packer, J. C. L., Vivarès, C. P., Doerig, C., & Barton, G. J. (2007) · BMC Genomics · doi:10.1186/1471-2164-8-309 · Cited by 74 · see citing works

Potential AMPK activators of cucurbitane triterpenoids from Siraitia grosvenorii Swingle

Chen, X.-B., Zhuang, J., Liu, J., Lei, M., Ma, L., Chen, J., Shen, X., & Hu, L. (2011) · Bioorganic & Medicinal Chemistry · doi:10.1016/j.bmc.2011.08.030 · Cited by 73 · see citing works

Ginsenoside Rg2 induces orphan nuclear receptor SHP gene expression and inactivates GSK3β via AMP-activated protein kinase to inhibit hepatic glucose production in HepG2 cells

Yuan, H.-D., Kim, D. Y., Quan, H.-Y., et al. (2011) · Chemico-Biological Interactions · doi:10.1016/j.cbi.2011.10.006 · Cited by 73 · see citing works

Accumulation and Membrane Transport of Plant Alkaloids

Shitan, N., & Yazaki, K. (2007) · Current Pharmaceutical Biotechnology · doi:10.2174/138920107781387429 · Cited by 73 · see citing works

CBS domains form energy-sensing modules whose binding of adenosine ligands is disrupted by disease mutations

Scott, J. W., Hawley, S. A., Green, K. A., et al. (2004) · Journal of Clinical Investigation · doi:10.1172/jci200419874 · Cited by 70 · see citing works

Phosphorylation and inactivation of HMG‐CoA reductase at the AMP‐activated protein kinase site in response to fructose treatment of isolated rat hepatocytes

Gillespie, J. G., & Hardie, D. G. (1992) · FEBS Letters · doi:10.1016/0014-5793(92)80837-7 · Cited by 69 · see citing works

THE TREATMENT OF ACUTE RHEUMATISM BY SALICIN.

Maclagan, T. J. (1876) · The Lancet · doi:10.1016/s0140-6736(02)49509-8 · Cited by 69 · see citing works

Mechanisms underlying the metabolic actions of galegine that contribute to weight loss in mice

Mooney, M. H., Fogarty, S., Stevenson, C. L., Gallagher, A. M., Palit, P., Hawley, S. A., Hardie, D. G., Coxon, G. D., Waigh, R. D., Tate, R. J., et al. (2008) · British Journal of Pharmacology · doi:10.1038/bjp.2008.37 · Cited by 68 · see citing works

Fatal Infantile Cardiac Glycogenosis with Phosphorylase Kinase Deficiency and a Mutation in the γ2-Subunit of AMP-Activated Protein Kinase

Akman, H. O., Sampayo, J. N., Ross, F. A., Scott, J. W., Wilson, G. J., Benson, L. N., Bruno, C., Shanske, S., Hardie, D. G., & DiMauro, S. (2007) · Pediatric Research · doi:10.1203/pdr.0b013e3181462b86 · Cited by 67 · see citing works

AMP-activated protein kinase (AMPK) activation is involved in chrysin-induced growth inhibition and apoptosis in cultured A549 lung cancer cells

Shao, J.-J., Zhang, A., Qin, W., Lin, Z., Zhu, Y., & Chen, X. (2012) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2012.05.123 · Cited by 67 · see citing works

Celastrol suppresses breast cancer MCF-7 cell viability via the AMP-activated protein kinase (AMPK)-induced p53–polo like kinase 2 (PLK-2) pathway

Kim, J. H., Lee, J. O., Lee, S. K., Kim, N., You, G. Y., Moon, J. W., Sha, J., Kim, S. J., Park, S. H., & Kim, H. S. (2012) · Cellular Signalling · doi:10.1016/j.cellsig.2012.12.005 · Cited by 66 · see citing works

Octaphlorethol A, a novel phenolic compound isolated from a brown alga, Ishige foliacea, increases glucose transporter 4-mediated glucose uptake in skeletal muscle cells

Lee, S., Kang, S., Ko, S., Lee, D.-H., & Jeon, Y. (2012) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2012.03.036 · Cited by 65 · see citing works

Methyl Cinnamate Inhibits Adipocyte Differentiation via Activation of the CaMKK2–AMPK Pathway in 3T3-L1 Preadipocytes

Chen, Y., Lee, M.-H., Hsu, C.-C., Wei, C.-L., & Tsai, Y.-C. (2012) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf203981x · Cited by 65 · see citing works

ReishiMax, mushroom based dietary supplement, inhibits adipocyte differentiation, stimulates glucose uptake and activates AMPK

Thyagarajan‐Sahu, A., Lane, B. C., & Slíva, D. (2011) · BMC Complementary and Alternative Medicine · doi:10.1186/1472-6882-11-74 · Cited by 64 · see citing works

Promotion of adiponectin multimerization by emodin: A novel AMPK activator with PPARγ‐agonist activity

Chen, Z., Zhang, L., Yi, J., Yang, Z., Zhang, Z., & Li, Z. (2012) · Journal of Cellular Biochemistry · doi:10.1002/jcb.24232 · Cited by 64 · see citing works

The inhibition of oleic acid induced hepatic lipogenesis and the promotion of lipolysis by caffeic acid via up‐regulation of AMP ‐activated kinase

Liao, C., Ou, T., Huang, H., & Wang, C. (2013) · Journal of the Science of Food and Agriculture · doi:10.1002/jsfa.6386 · Cited by 62 · see citing works

Hispidulin Sensitizes Human Ovarian Cancer Cells to TRAIL-Induced Apoptosis by AMPK Activation Leading to Mcl-1 Block in Translation

Yang, J.-M., Hung, C., Fu, C.-N., Lee, J., Huang, C.-H., Yang, M., Lin, C., Kao, J., & Way, T. (2010) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf102304g · Cited by 62 · see citing works

Osthole Enhances Glucose Uptake through Activation of AMP-Activated Protein Kinase in Skeletal Muscle Cells

Lee, W., Lin, R.-J., Lin, S.-Y., et al. (2011) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf2036559 · Cited by 61 · see citing works

Extracts of Scutellaria baicalensis Reduced Body Weight and Blood Triglyceride in db/db Mice

Song, K. H., Lee, S. H., Kim, B., Park, A. Y., & Kim, J. Y. (2012) · Phytotherapy Research · doi:10.1002/ptr.4691 · Cited by 60 · see citing works

Apigenin, a chemopreventive bioflavonoid, induces AMP‐activated protein kinase activation in human keratinocytes

Tong, X., Smith, K. A., & Pelling, J. C. (2011) · Molecular Carcinogenesis · doi:10.1002/mc.20793 · Cited by 58 · see citing works

Boesenbergia pandurata Attenuates Diet-Induced Obesity by Activating AMP-Activated Protein Kinase and Regulating Lipid Metabolism

Kim, D., Kim, M., Sa, B.-K., Kim, M., & Hwang, J. (2012) · International Journal of Molecular Sciences · doi:10.3390/ijms13010994 · Cited by 55 · see citing works

Ginsenoside Rd stimulates the differentiation and mineralization of osteoblastic MC3T3-E1 cells by activating AMP-activated protein kinase via the BMP-2 signaling pathway

Kim, D. Y., Park, Y., Quan, H.-Y., et al. (2011) · Fitoterapia · doi:10.1016/j.fitote.2011.10.017 · Cited by 43 · see citing works

Arctigenin Efficiently Enhanced Sedentary Mice Treadmill Endurance

Tang, X., Zhuang, J., Chen, J., Yu, L., Hu, L., Jiang, H., & Shen, X. (2011) · PLoS ONE · doi:10.1371/journal.pone.0024224 · Cited by 42 · see citing works

Anticancer Properties of Pomolic Acid-Induced AMP-Activated Protein Kinase Activation in MCF7 Human Breast Cancer Cells

Youn, S. H., Lee, J., Lee, M. S., Cha, E. Y., Thương, P. T., Kim, J. R., & Chang, E. S. (2012) · Biological and Pharmaceutical Bulletin · doi:10.1248/bpb.35.105 · Cited by 39 · see citing works

Tanshinone IIA improves endoplasmic reticulum stress-induced insulin resistance through AMP-activated protein kinase

Hwang, S., Yang, J., Jeong, Y., Kim, Y. D., Li, X., Lü, Y., Chang, Y., Son, K. H., & Chang, H. W. (2012) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2012.12.066 · Cited by 37 · see citing works

Karanjin from Pongamia pinnata induces GLUT4 translocation in skeletal muscle cells in a phosphatidylinositol-3-kinase-independent manner

Jaiswal, N., Yadav, P. P., Maurya, R., Srivastava, A. K., & Tamrakar, A. K. (2011) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2011.08.049 · Cited by 37 · see citing works

Inhibition by AICA riboside of gluconeogenesis in isolated rat hepatocytes

Vincent, M. F., Marangos, P. J., Gruber, H. E., et al. (1991) · Diabetes · doi:10.2337/diabetes.40.10.1259 · Cited by 37 · see citing works

Phosphorylation of hepatic AMP-activated protein kinase and liver kinase B1 is increased after a single oral dose of green tea extract to mice

Banerjee, S., Ghoshal, S., & Porter, T. D. (2012) · Nutrition Research · doi:10.1016/j.nutres.2012.10.005 · Cited by 34 · see citing works

Emodin Protects against High-Fat Diet-Induced Obesity via Regulation of AMP-Activated Protein Kinase Pathways in White Adipose Tissue

Tzeng, T., Lu, H.-J., Liou, S., et al. (2012) · Planta Medica · doi:10.1055/s-0031-1298626 · Cited by 33 · see citing works

Foenumoside B from Lysimachia foenum-graecum inhibits adipocyte differentiation and obesity induced by high-fat diet

Seo, J. B., Park, S. W., Choe, S. S., Jeong, H. W., Park, J. Y., Choi, E.-W., Seen, D., Jeong, J.-Y., & Lee, T. G. (2011) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2011.12.039 · Cited by 31 · see citing works

2-(2,4-dihydroxyphenyl)-5-(E)-propenylbenzofuran promotes endothelial nitric oxide synthase activity in human endothelial cells

Ladurner, A., Atanasov, A. G., Heiß, E. H., Baumgartner, L., Schwaiger, S., Rollinger, J. M., Stuppner, H., & Dirsch, V. M. (2012) · Biochemical Pharmacology · doi:10.1016/j.bcp.2012.06.029 · Cited by 28 · see citing works

Alternol exerts prostate‐selective antitumor effects through modulations of the AMPK signaling pathway

Yeung, E., Morrison, A., Plumeri, D., et al. (2011) · The Prostate · doi:10.1002/pros.21417 · Cited by 28 · see citing works

THE TREATMENT OF ACUTE RHEUMATISM BY SALICIN AND SALICYLIC ACID.

Maclagan, T. J. (1879) · The Lancet · doi:10.1016/s0140-6736(02)46061-8 · Cited by 28 · see citing works

Aglycon of Rhizochalin from the Rhizochalina incrustata Induces Apoptosis via Activation of AMP-Activated Protein Kinase in HT-29 Colon Cancer Cells

Khanal, P., Kang, B. S., Yun, H. J., Cho, H., Makarieva, T. N., & Choi, H. S. (2011) · Biological and Pharmaceutical Bulletin · doi:10.1248/bpb.34.1553 · Cited by 27 · see citing works

TG accumulation inhibitory effects of Jinqi formula by AMPK signaling pathway

Qian, Q., Liu, X., He, W., An, Y., Chen, Q., Wu, J., Deng, Y., Guo, L., Zhang, Y., & Wang, T. (2012) · Journal of Ethnopharmacology · doi:10.1016/j.jep.2012.05.052 · Cited by 25 · see citing works

Inhibitory Effect of Vitamin U (S-Methylmethionine Sulfonium Chloride) on Differentiation in 3T3-L1 Pre-adipocyte Cell Lines

Lee, N. Y., Park, K. Y., Min, H. J., Song, K. Y., Lim, Y. Y., Park, J.-H., Kim, B. J., & Kim, M. N. (2012) · Annals of Dermatology · doi:10.5021/ad.2012.24.1.39 · Cited by 24 · see citing works

Fargesin improves lipid and glucose metabolism in 3T3‐L1 adipocytes and high‐fat diet‐induced obese mice

Lee, Y., Cha, B., Choi, S., Harada, Y., Choi, B., Yonezawa, T., Teruya, T., Nagai, K., & Woo, J. (2012) · BioFactors · doi:10.1002/biof.1022 · Cited by 24 · see citing works

Anti-inflammatory effects of lindenenyl acetate via heme oxygenase-1 and AMPK in human periodontal ligament cells

Jeong, G., Lee, D., Li, B., Kim, J.-J., Kim, E.-C., & Kim, Y. (2011) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2011.08.008 · Cited by 22 · see citing works

Antidiabetic Activities of Extract from Malva verticillata Seed via the Activation of AMP-Activated Protein Kinase

Jeong, Y. (2011) · Journal of Microbiology and Biotechnology · doi:10.4014/jmb.1104.04015 · Cited by 20 · see citing works

The herbal composition GGEx18 fromLaminaria japonica, Rheum palmatum, andEphedra sinicareduces obesity via skeletal muscle AMPK and PPARα

Shin, S. S., Park, D., Lee, H. Y., Hong, Y., Choi, J., Oh, J.-H., Lee, H., Lee, H. R., Kim, M.-R., Shen, Z. B., et al. (2011) · Pharmaceutical Biology · doi:10.3109/13880209.2011.618502 · Cited by 17 · see citing works

Ethanolic Extract ofVitis thunbergiiExhibits Lipid Lowering Properties via Modulation of the AMPK-ACC Pathway in Hypercholesterolemic Rabbits

Pan, C., Tsai, C.-H., Lin, W., Chen, G.-Y., & Wu, C. (2012) · Evidence-based Complementary and Alternative Medicine · doi:10.1155/2012/436786 · Cited by 15 · see citing works

The treatment of acute rheumatism by salicin, by T.J. Maclagan--The Lancet, 1876.

Buchanan, W. W., & Kean, W. F. (2002) · PubMed · Cited by 13 · see citing works

The 1,4-naphthoquinone derivative from Pyrola rotundifolia activates AMPK phosphorylation in C2C12 myotubes

Ptitsyn, L. R., Nomura, K., Sklyar, I. V., et al. (2011) · Fitoterapia · doi:10.1016/j.fitote.2011.09.005 · Cited by 11 · see citing works

Attenuation of tumor growth by honokiol: An evolving role in oncology

Kapoor (2012) · Drug Discoveries & Therapeutics · doi:10.5582/ddt.2012.v6.6.327 · Cited by 4 · see citing works

Mechanisms of activation of the transcription factor Nrf2 by redox stressors, nutrient cues, and energy status and the pathways through which it attenuates degenerative disease

Tebay, L. E., Robertson, H., Durant, S. T., Vitale, S. R., Penning, T. M., Dinkova-Kostova, A. T., & Hayes, J. D. (2015) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2015.06.021 · Cited by 837 · see citing works

AMPK activators: mechanisms of action and physiological activities

Kim, J., Yang, G., Kim, Y., Kim, J., & Ha, J. (2016) · Experimental &amp; Molecular Medicine · doi:10.1038/emm.2016.16 · Cited by 817 · see citing works

Systemic pan-AMPK activator MK-8722 improves glucose homeostasis but induces cardiac hypertrophy

Myers, R. W., Guan, H.-P., Ehrhart, J., Petrov, A., Prahalada, S., Tozzo, E., Yang, X., Kurtz, M. M., Trujillo, M., Gonzalez Trotter, D., et al. (2017) · Science · doi:10.1126/science.aah5582 · Cited by 346 · see citing works

Role of mitochondria in the mechanism(s) of action of metformin

Vial, G., Detaille, D., & Guigas, B. (2019) · Frontiers in Endocrinology · doi:10.3389/fendo.2019.00294 · Cited by 303 · see citing works

Emerging Role of cAMP/AMPK Signaling

Aslam, M., & Ladilov, Y. (2022) · Cells · doi:10.3390/cells11020308 · Cited by 241 · see citing works

Differential regulation by AMP and ADP of AMPK complexes containing different γ subunit isoforms

Ross, F. A., Jensen, T. E., & Hardie, D. G. (2016) · Biochemical Journal · doi:10.1042/bj20150910 · Cited by 172 · see citing works

Eukaryotic elongation factor 2 kinase as a drug target in cancer, and in cardiovascular and neurodegenerative diseases

Liu, R., & Proud, C. G. (2016) · Acta Pharmacologica Sinica · doi:10.1038/aps.2015.123 · Cited by 117 · see citing works

Mitochondrial dysfunction and tissue injury by alcohol, high fat, nonalcoholic substances and pathological conditions through post-translational protein modifications

Song, B.-J., Akbar, M., Abdelmegeed, M. A., Byun, K., Lee, B., Yoon, S. K., & Hardwick, J. P. (2014) · Redox Biology · doi:10.1016/j.redox.2014.10.004 · Cited by 123 · see citing works

Diet and physical exercise as key players to tackle MASLD through improvement of insulin resistance and metabolic flexibility

Mambrini, S. P., Grillo, A., Colosimo, S., Zarpellon, F., Pozzi, G., Furlan, D., Amodeo, G., & Bertoli, S. (2024) · Frontiers in Nutrition · doi:10.3389/fnut.2024.1426551 · Cited by 70 · see citing works

Metformin activation of AMPK suppresses AGE-induced inflammatory response in hNSCs

Chung, M.-M., Nicol, C. J., Cheng, Y.-C., Lin, K.-H., Chen, Y.-L., Pei, D., Lin, C.-H., Shih, Y.-N., Yen, C.-H., Chen, S.-J., et al. (2017) · Experimental Cell Research · doi:10.1016/j.yexcr.2017.01.017 · Cited by 66 · see citing works

Discovery of MK-8722: A systemic, direct pan-activator of amp-activated protein kinase

Feng, D., Biftu, T., Romero, F. A., Kekec, A., Dropinski, J., Kassick, A., Xu, S., Kurtz, M. M., Gollapudi, A., Shao, Q., et al. (2018) · ACS Medicinal Chemistry Letters · doi:10.1021/acsmedchemlett.7b00417 · Cited by 64 · see citing works

Eukaryotic elongation factor-2 kinase (eEF2K) signaling in tumor and microenvironment as a novel molecular target

Karakas, D., & Ozpolat, B. (2020) · Journal of Molecular Medicine · doi:10.1007/s00109-020-01917-8 · Cited by 54 · see citing works

Sensing and responding to energetic stress: Evolution of the AMPK network

Craig, P. M., Moyes, C. D., & LeMoine, C. M. R. (2018) · Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular Biology · doi:10.1016/j.cbpb.2017.11.001 · Cited by 46 · see citing works

Minimal requirements for a neuron to coregulate many properties and the implications for ion channel correlations and robustness

Yang, J., Shakil, H., Ratté, S., & Prescott, S. A. (2022) · eLife · doi:10.7554/elife.72875 · Cited by 41 · see citing works

Insulin resistance and metabolic flexibility as drivers of liver and cardiac disease in T2DM

Colosimo, S., Mitra, S. K., Chaudhury, T., & Marchesini, G. (2023) · Diabetes Research and Clinical Practice · doi:10.1016/j.diabres.2023.111016 · Cited by 38 · see citing works

1H-NMR metabolomics reveals the Glabrescione B exacerbation of glycolytic metabolism beside the cell growth inhibitory effect in glioma

D’Alessandro, G., Quaglio, D., Monaco, L., Lauro, C., Ghirga, F., Ingallina, C., De Martino, M., Fucile, S., Porzia, A., Di Castro, M. A., et al. (2019) · Cell Communication and Signaling · doi:10.1186/s12964-019-0421-8 · Cited by 32 · see citing works

Pharmacological Targeting of AMP-Activated Protein Kinase and Opportunities for Computer-Aided Drug Design: Miniperspective

Miglianico, M., Nicolaes, G. A. F., & Neumann, D. (2016) · Journal of Medicinal Chemistry · doi:10.1021/acs.jmedchem.5b01201 · Cited by 24 · see citing works

Pharmacologic targeting of eEF2K in cardiovascular diseases: Mechanisms and potential clinical applications

Rezabakhsh, A., Habtemariam, S., Khani, E., Ghorbani Yekta, B., Rahmani, R., Iraji, H., & Nabavi, S. M. (2025) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2025.178253 · Cited by 3 · see citing works

Hypothalamic PDE3B deficiency alters body weight and glucose homeostasis in mouse

Sahu, M., Anamthathmakula, P., & Sahu, A. (2018) · Journal of Endocrinology · doi:10.1530/joe-18-0304 · Cited by 6 · see citing works

Hypothalamic Proopiomelanocortin Is Necessary for Normal Glucose Homeostasis in Female Mice

Alsina, R., Trotta, M., & Bumaschny, V. F. (2018) · Frontiers in Endocrinology · doi:10.3389/fendo.2018.00554 · Cited by 9 · see citing works

Central Nervous System Nutrient-sensing and the Regulation of Energy and Glucose Homeostasis

Lam, K. L. C. (2010) · TSpace (University of Toronto)

Role of probiotics in modulating glucose homeostasis: evidence from animal and human studies

Firouzi, S., Yusof, B. N. M., Ismail, A., Majid, H. A., & Azmi, K. N. (2013) · International Journal of Food Sciences and Nutrition · doi:10.3109/09637486.2013.775227 · Cited by 26 · see citing works

Wired on sugar: the role of the CNS in the regulation of glucose homeostasis

Grayson, B. E., Seeley, R. J., & Sandoval, D. A. (2012) · Nature reviews. Neuroscience · doi:10.1038/nrn3409 · Cited by 122 · see citing works