The protein secretory pathway of Candida albicans

SNAREs — engines for membrane fusion

Jahn, R., & Scheller, R. H. (2006) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm2002 · Cited by 2,635 · see citing works

Membrane Fusion

Wilschut, J. (1990) · Cited by 2,414 · see citing works

The Mechanisms of Vesicle Budding and Fusion

Bonifacino, J. S., & Glick, B. S. (2004) · Cell · doi:10.1016/s0092-8674(03)01079-1 · Cited by 1,863 · see citing works

Proof and evolutionary analysis of ancient genome duplication in the yeast Saccharomyces cerevisiae

Kellis, M., Birren, B. W., & Lander, E. S. (2004) · Nature · doi:10.1038/nature02424 · Cited by 1,500 · see citing works

Membrane Fusion

Jahn, R., Lang, T., & Südhof, T. C. (2003) · Cell · doi:10.1016/s0092-8674(03)00112-0 · Cited by 1,331 · see citing works

X-ray structure of a protein-conducting channel

van den Berg, B., Clemons, W., Collinson, I. R., Modis, Y., Hartmann, E., Harrison, S. C., & Rapoport, T. A. (2003) · Nature · doi:10.1038/nature02218 · Cited by 1,252 · see citing works

BI-DIRECTIONAL PROTEIN TRANSPORT BETWEEN THE ER AND GOLGI

Lee, M., Miller, E. A., Goldberg, J. D., Orci, L., & Schekman, R. W. (2004) · Annual Review of Cell and Developmental Biology · doi:10.1146/annurev.cellbio.20.010403.105307 · Cited by 909 · see citing works

The diversity of Rab proteins in vesicle transport

Novick, P., & Zerial, M. (1997) · Current Opinion in Cell Biology · doi:10.1016/s0955-0674(97)80025-7 · Cited by 767 · see citing works

Cell Wall and Secreted Proteins of<i>Candida albicans</i>: Identification, Function, and Expression

Chaffin, W. L., López-Ribot, J. L., Casanova, M., Gozalbo, D., & Martínez, J. P. (1998) · Microbiology and Molecular Biology Reviews · doi:10.1128/mmbr.62.1.130-180.1998 · Cited by 726 · see citing works

A genomic perspective on membrane compartment organization

Bock, J. B., Matern, H. T., Peden, A. A., & Scheller, R. H. (2001) · Nature · doi:10.1038/35057024 · Cited by 696 · see citing works

Coats, Tethers, Rabs, and SNAREs Work Together to Mediate the Intracellular Destination of a Transport Vesicle

Cai, H., Reinisch, K. M., & Ferro‐Novick, S. (2007) · Developmental Cell · doi:10.1016/j.devcel.2007.04.005 · Cited by 686 · see citing works

The mystery of nonclassical protein secretion

Nickel, W. (2003) · European Journal of Biochemistry · doi:10.1046/j.1432-1033.2003.03577.x · Cited by 586 · see citing works

Membrane-protein topology

von HEIJNE, G. (2006) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm2063 · Cited by 539 · see citing works

How to build a biofilm: a fungal perspective

Blankenship, J. R., & Mitchell, A. P. (2006) · Current Opinion in Microbiology · doi:10.1016/j.mib.2006.10.003 · Cited by 530 · see citing works

Large‐scale essential gene identification in Candida albicans and applications to antifungal drug discovery

Roemer, T., Jiang, B., Davison, J., Ketela, T. W., Veillette, K., Breton, A., Tandia, F., Linteau, A., Sillaots, S., Marta, C., et al. (2003) · Molecular Microbiology · doi:10.1046/j.1365-2958.2003.03697.x · Cited by 513 · see citing works

Hydrolytic enzymes as virulence factors of <i>Candida albicans</i>

Schaller, M., Borelli, C., Korting, H. C., & Hube, B. (2005) · Mycoses · doi:10.1111/j.1439-0507.2005.01165.x · Cited by 506 · see citing works

Vesicle tethering complexes in membrane traffic

Whyte, J. R. C., & Munro, S. (2002) · Journal of Cell Science · doi:10.1242/jcs.115.13.2627 · Cited by 457 · see citing works

A novel GTP-binding protein, Sar1p, is involved in transport from the endoplasmic reticulum to the Golgi apparatus.

Nakano, A., & Muramatsu, M. (1989) · The Journal of Cell Biology · doi:10.1083/jcb.109.6.2677 · Cited by 452 · see citing works

Type I secretion in gram-negative bacteria

Delepelaire, P. (2004) · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research · doi:10.1016/j.bbamcr.2004.05.001 · Cited by 411 · see citing works

The Unfolding Tale of the Unfolded Protein Response

Ma, Y., & Hendershot, L. M. (2001) · Cell · doi:10.1016/s0092-8674(01)00623-7 · Cited by 401 · see citing works

Contributions of hyphae and hypha-co-regulated genes to Candida albicans virulence

Kumamoto, C. A., & Vinces, M. D. (2005) · Cellular Microbiology · doi:10.1111/j.1462-5822.2005.00616.x · Cited by 388 · see citing works

Sec3p Is a Spatial Landmark for Polarized Secretion in Budding Yeast

Finger, F. P., Hughes, T. E., & Novick, P. (1998) · Cell · doi:10.1016/s0092-8674(00)80948-4 · Cited by 384 · see citing works

Discovering the secrets of the<i>Candida albicans</i>agglutinin-like sequence (ALS) gene family – a sticky pursuit

Hoyer, L. L., Green, C. B., Oh, S.-H., & Zhao, X. (2008) · Medical Mycology · doi:10.1080/13693780701435317 · Cited by 356 · see citing works

Vesicular transport inHistoplasma capsulatum: an effective mechanism for trans-cell wall transfer of proteins and lipids in ascomycetes

Albuquerque, P. C., Nakayasu, E. S., Rodrigues, M. L., Frasés, S., Casadevall, A., Zancopé‐Oliveira, R. M., de Almeida, I. C., & Nosanchuk, J. D. (2008) · Cellular Microbiology · doi:10.1111/j.1462-5822.2008.01160.x · Cited by 347 · see citing works

A Human-Curated Annotation of the Candida albicans Genome

Braun, B. R., van het Hoog, M., d'Enfert, C., Martchenko, M., Dungan, J., Kuo, A., Inglis, D. O., Uhl, M. A., Hogues, H., Berriman, M., et al. (2005) · PLoS Genetics · doi:10.1371/journal.pgen.0010001 · Cited by 342 · see citing works

Adhesion in Candida spp

Sundstrom, P. (2002) · Cellular Microbiology · doi:10.1046/j.1462-5822.2002.00206.x · Cited by 336 · see citing works

Heat Shock Protein 70 Is Secreted from Tumor Cells by a Nonclassical Pathway Involving Lysosomal Endosomes

Mambula, S. S., & Calderwood, S. K. (2006) · The Journal of Immunology · doi:10.4049/jimmunol.177.11.7849 · Cited by 335 · see citing works

Polarisome Meets Spitzenkorper: Microscopy, Genetics, and Genomics Converge

Harris, S. D., Read, N. D., Roberson, R. W., Shaw, B. D., Seiler, S., Plamann, M., & Momany, M. (2005) · Eukaryotic Cell · doi:10.1128/ec.4.2.225-229.2005 · Cited by 279 · see citing works

Genome-wide identification of fungal GPI proteins.

de Groot, P. W. J., Hellingwerf, K. J., & Klis, F. M. (2003) · Yeast · doi:10.1002/yea.1007 · Cited by 276 · see citing works

TRAPPI tethers COPII vesicles by binding the coat subunit Sec23

Cai, H., Yu, S. S. B., Menon, S., Cai, Y., Lazarova, D. L., Fu, C., Reinisch, K. M., Hay, J., & Ferro‐Novick, S. (2007) · Nature · doi:10.1038/nature05527 · Cited by 238 · see citing works

Outer Chain N-Glycans Are Required for Cell Wall Integrity and Virulence of Candida albicans

Bates, S., Hughes, H. B., Munro, C. A., Thomas, W. P. H., MacCallum, D. M., Bertram, G., Atrih, A., Ferguson, M. A. J., Brown, A. J. P., Odds, F. C., et al. (2005) · Journal of Biological Chemistry · doi:10.1074/jbc.m510360200 · Cited by 238 · see citing works

Essential Gene Identification and Drug Target Prioritization in Aspergillus fumigatus

Hu, W., Sillaots, S., Lemieux, S., Davison, J., Kauffman, S., Breton, A., Linteau, A., Xin, C., Bowman, J., Becker, J., et al. (2007) · PLoS Pathogens · doi:10.1371/journal.ppat.0030024 · Cited by 237 · see citing works

Targeting proteins to membranes: structure of the signal recognition particle

Egea, P. F., Stroud, R. M., & Walter, P. (2005) · Current Opinion in Structural Biology · doi:10.1016/j.sbi.2005.03.007 · Cited by 236 · see citing works

Mechanisms of COPII vesicle formation and protein sorting

Sato, K., & Nakano, A. (2007) · FEBS Letters · doi:10.1016/j.febslet.2007.01.091 · Cited by 235 · see citing works

Interleukin-1β Secretion Is Impaired by Inhibitors of the Atp Binding Cassette Transporter, ABC1

Hamon, Y., Luciani, M., Becq, F., Verrier, B., Rubartelli, A., & Chimini, G. (1997) · Blood · doi:10.1182/blood.v90.8.2911 · Cited by 224 · see citing works

Non-conventional protein secretionin yeast

Nombela, C., Gil, C., & Chaffin, W. L. (2005) · Trends in Microbiology · doi:10.1016/j.tim.2005.11.009 · Cited by 211 · see citing works

Candida albicans biofilm development, modeling a host–pathogen interaction

Nett, J., & Andes, D. (2006) · Current Opinion in Microbiology · doi:10.1016/j.mib.2006.06.007 · Cited by 210 · see citing works

A new pathway for protein export in Saccharomyces cerevisiae.

Cleves, A. E., Cooper, D. N., Barondes, S. H., & Kelly, R. B. (1996) · The Journal of Cell Biology · doi:10.1083/jcb.133.5.1017 · Cited by 206 · see citing works

Candida albicans hyphae have a Spitzenkorper that is distinct from the polarisome found in yeast and pseudohyphae

Crampin, H., Finley, K. R., Gerami‐Nejad, M., Court, H., Gale, C. A., Berman, J. G., & Sudbery, P. E. (2005) · Journal of Cell Science · doi:10.1242/jcs.02414 · Cited by 187 · see citing works

The Architecture of the Multisubunit TRAPP I Complex Suggests a Model for Vesicle Tethering

Kim, Y., Raunser, S., Munger, C., Wagner, J., Song, Y.-L., Cygler, M., Walz, T., Oh, B., & Sacher, M. G. (2006) · Cell · doi:10.1016/j.cell.2006.09.029 · Cited by 174 · see citing works

A Complete Set of SNAREs in Yeast

Burri, L., & Lithgow, T. J. (2003) · Traffic · doi:10.1046/j.1600-0854.2003.00151.x · Cited by 164 · see citing works

The germ tubes of Candida albicans hyphae and pseudohyphae show different patterns of septin ring localization

Sudbery, P. E. (2001) · Molecular Microbiology · doi:10.1046/j.1365-2958.2001.02459.x · Cited by 161 · see citing works

Polarized growth and organelle segregation in yeast

Bretscher, A. P. (2003) · The Journal of Cell Biology · doi:10.1083/jcb.200301035 · Cited by 149 · see citing works

Endoplasmic Reticulum α-Glycosidases of Candida albicans Are Required for N Glycosylation, Cell Wall Integrity, and Normal Host-Fungus Interaction

Mora-Montes, H. M., Bates, S., Netea, M. G., Díaz-Jiménez, D. F., López-Romero, E., Zinker, S., Ponce‐Noyola, P., Kullberg, B. J., Brown, A. J. P., Odds, F. C., et al. (2007) · Eukaryotic Cell · doi:10.1128/ec.00350-07 · Cited by 149 · see citing works

Exomer: a coat complex for transport of select membrane proteins from the trans-Golgi network to the plasma membrane in yeast

Wang, C.-W., Hamamoto, S., Orci, L., & Schekman, R. (2006) · Journal of Cell Biology · doi:10.1083/jcb.200605106 · Cited by 141 · see citing works

Integrated Proteomics and Genomics Strategies Bring New Insight into Candida albicans Response upon Macrophage Interaction

Fernández‐Arenas, E., Cabezón, V., Bermejo, C., Arroyo, J., Nombela, C., Diez‐Orejas, R., & Gil, C. (2006) · Molecular & Cellular Proteomics · doi:10.1074/mcp.m600210-mcp200 · Cited by 131 · see citing works

Mechanism of Polypeptide Translocation into the Endoplasmic Reticulum

Corsi, A. K., & Schekman, R. W. (1996) · Journal of Biological Chemistry · doi:10.1074/jbc.271.48.30299 · Cited by 131 · see citing works

The machinery of membrane protein assembly

White, S. H., & von HEIJNE, G. (2004) · Current Opinion in Structural Biology · doi:10.1016/j.sbi.2004.07.003 · Cited by 130 · see citing works

Involvement of BNIP1 in apoptosis and endoplasmic reticulum membrane fusion

Nakajima, K., Hirose, H., Taniguchi, M., Kurashina, H., Arasaki, K., Nagahama, M., Tani, K., Yamamoto, A., & Tagaya, M. (2004) · The EMBO Journal · doi:10.1038/sj.emboj.7600333 · Cited by 128 · see citing works

Cryptococcus neoformans: the yeast that likes it hot

Perfect, J. R. (2006) · FEMS Yeast Research · doi:10.1111/j.1567-1364.2006.00051.x · Cited by 122 · see citing works

Ras family therapy: Rab, Rho and Ral talk to the exocyst

Novick, P., & Guo, W. (2002) · Trends in Cell Biology · doi:10.1016/s0962-8924(02)02293-6 · Cited by 118 · see citing works

Impact of the unfolded protein response upon genome-wide expression patterns, and the role of Hac1 in the polarized growth, of Candida albicans

Wimalasena, T. T., Enjalbert, B., Guillemette, T., Plumridge, A., Budge, S., Yin, Z., Brown, A. J. P., & Archer, D. B. (2008) · Fungal Genetics and Biology · doi:10.1016/j.fgb.2008.06.001 · Cited by 118 · see citing works

Threonine-Rich Repeats Increase Fibronectin Binding in the <i>Candidaalbicans</i> Adhesin Als5p

Rauceo, J. M., De Armond, R., Otoo, H., Kahn, P. C., Klotz, S. A., Gaur, N. K., & Lipke, P. N. (2006) · Eukaryotic Cell · doi:10.1128/ec.00120-06 · Cited by 115 · see citing works

Septin Function in Yeast Model Systems and Pathogenic Fungi

Douglas, L. M., Álvarez, F. J., McCreary, C., & Konopka, J. B. (2005) · Eukaryotic Cell · doi:10.1128/ec.4.9.1503-1512.2005 · Cited by 115 · see citing works

CDC42 Is Required for Polarized Growth in Human Pathogen Candida albicans

Ushinsky, S. C., Harcus, D., Ash, J., Dignard, D., Marcil, A., Morchhauser, J., Thomas, D. Y., Whiteway, M. S., & Leberer, E. (2002) · Eukaryotic Cell · doi:10.1128/ec.1.1.95-104.2002 · Cited by 113 · see citing works

Rho GTPase regulation of exocytosis in yeast is independent of GTP hydrolysis and polarization of the exocyst complex

Roumanie, O., Wu, H., Molk, J. N., Rossi, G., Bloom, K., & Brennwald, P. (2005) · The Journal of Cell Biology · doi:10.1083/jcb.200504108 · Cited by 109 · see citing works

Dsl1p, Tip20p, and the Novel Dsl3(Sec39) Protein Are Required for the Stability of the Q/t-SNARE Complex at the Endoplasmic Reticulum in Yeast

Kraynack, B. A., Chan, A., Rosenthal, E. H., Essid, M., Umansky, B., Waters, M. G., & Schmitt, H. D. (2005) · Molecular Biology of the Cell · doi:10.1091/mbc.e05-01-0056 · Cited by 106 · see citing works

Candida-host cell receptor-ligand interactions.

Filler, S. (2006) · Current Opinion in Microbiology · doi:10.1016/j.mib.2006.06.005 · Cited by 104 · see citing works

Identification of <i>Candida albicans ALS2</i> and <i>ALS4</i> and Localization of Als Proteins to the Fungal Cell Surface

Hoyer, L. L., Payne, T. L., & Hecht, J. E. (1998) · Journal of Bacteriology · doi:10.1128/jb.180.20.5334-5343.1998 · Cited by 103 · see citing works

Initial characterization of the nascent polypeptide-associated complex in yeast

Reimann, B., Bradsher, J., Franke, J., Hartmann, E., Wiedmann, M., Prehn, S., & Wiedmann, B. (1999) · Yeast · doi:10.1002/(sici)1097-0061(19990330)15:5 · Cited by 92 · see citing works

Genetic control of chlamydospore formation in Candida albicans

Nobile, C. J., Bruno, V. M., Richard, M. L., Davis, D. A., & Mitchell, A. P. (2003) · Microbiology · doi:10.1099/mic.0.26640-0 · Cited by 89 · see citing works

The Saccharomyces cerevisiae SEC20 gene encodes a membrane glycoprotein which is sorted by the HDEL retrieval system.

Sweet, D. J., & Pelham, H. R. B. (1992) · The EMBO Journal · doi:10.1002/j.1460-2075.1992.tb05071.x · Cited by 89 · see citing works

Identification of pH-Regulated Antigen 1 Released from Candida albicans as the Major Ligand for Leukocyte Integrin αMβ2

Soloviev, D. A., Fonzi, W. A., Sentandreu, R., Pluskota, E., Forsyth, C. B., Yadav, S. P., & Plow, E. F. (2007) · The Journal of Immunology · doi:10.4049/jimmunol.178.4.2038 · Cited by 82 · see citing works

The Sec14-superfamily and the regulatory interface between phospholipid metabolism and membrane trafficking

Mousley, C. J., Tyeryar, K. R., Vincent-Pope, P., & Bankaitis, V. A. (2007) · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids · doi:10.1016/j.bbalip.2007.04.002 · Cited by 81 · see citing works

Predicting the distribution, conservation, and functions of SNAREs and related proteins in fungi

Gupta, G. D., & Heath, I. B. (2002) · Fungal Genetics and Biology · doi:10.1016/s1087-1845(02)00017-8 · Cited by 80 · see citing works

Mating‐type locus homozygosis, phenotypic switching and mating: a unique sequence of dependencies in Candida albicans

Soll, D. R. (2003) · BioEssays · doi:10.1002/bies.10379 · Cited by 79 · see citing works

Snapshots of ARF1

Roth, M. G. (1999) · Cell · doi:10.1016/s0092-8674(00)80723-0 · Cited by 77 · see citing works

Inactivation of Kex2p Diminishes the Virulence of Candida albicans

Newport, G., Kuo, A., Flattery, A. M., Gill, C., Blake, J., Kurtz, M. B., Abruzzo, G. K., & Agabian, N. M. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m209713200 · Cited by 77 · see citing works

An analysis of the Candida albicans genome database for soluble secreted proteins using computer‐based prediction algorithms

Lee, S. A., Wormsley, S., Kamoun, S., Lee, A. F. S., Joiner, K. A., & Wong, B. (2003) · Yeast · doi:10.1002/yea.988 · Cited by 75 · see citing works

Sep7 Is Essential to Modify Septin Ring Dynamics and Inhibit Cell Separation during<i>Candida albicans</i>Hyphal Growth

González-Novo, A., Correa-Bordes, J., Labrador, L., Sánchez, M., Vázquez de Aldana, C. R., & Jiménez, J. (2008) · Molecular Biology of the Cell · doi:10.1091/mbc.e07-09-0876 · Cited by 75 · see citing works

The ADP Ribosylation Factor-Nucleotide Exchange Factors Gea1p and Gea2p Have Overlapping, but Not Redundant Functions in Retrograde Transport from the Golgi to the Endoplasmic Reticulum

Spang, A., Herrmann, J. M., Hamamoto, S., & Schekman, R. W. (2001) · Molecular Biology of the Cell · doi:10.1091/mbc.12.4.1035 · Cited by 75 · see citing works

Unusual routes of protein secretion: the easy way out

Kuchler, K. (1993) · Trends in Cell Biology · doi:10.1016/0962-8924(93)90030-5 · Cited by 73 · see citing works

A general mechanism for regulation of access to the translocon: Competition for a membrane attachment site on ribosomes

Möller, I., Jung, M., Beatrix, B., Levy, R. J., Kreibich, G., Zimmermann, R., Wiedmann, M., & Lauring, B. P. (1998) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.95.23.13425 · Cited by 72 · see citing works

Low virulent strains of Candida albicans: Unravelling the antigens for a future vaccine

Fernández‐Arenas, E., Molero, G., Nombela, C., Diez‐Orejas, R., & Gil, C. (2004) · PROTEOMICS · doi:10.1002/pmic.200400929 · Cited by 69 · see citing works

Molecular and Phenotypic Analysis ofCaVRG4, Encoding an Essential Golgi Apparatus GDP-Mannose Transporter

Nishikawa, A., Poster, J. B., Jigami, Y., & Dean, N. (2002) · Journal of Bacteriology · doi:10.1128/jb.184.1.29-42.2002 · Cited by 65 · see citing works

Protein-O-mannosyltransferases in virulence and development

Lengeler, K. B., Tielker, D., & Ernst, J. F. (2007) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-007-7409-z · Cited by 64 · see citing works

Computational and experimental approaches double the number of known introns in the pathogenic yeast Candida albicansPreprint

Mitrovich, Q. M., Tuch, B. B., Guthrie, C., & Johnson, A. D. (2007) · Genome Research · doi:10.1101/gr.6111907 · Cited by 64 · see citing works

Candida albicanshyphal morphogenesis occurs in Sec3p-independent and Sec3p-dependent phases separated by septin ring formation

Li, C.-R., Lee, R. T.-H., Wang, Y.-M., Zheng, X., & Wang, Y. (2007) · Journal of Cell Science · doi:10.1242/jcs.002931 · Cited by 64 · see citing works

Spatial regulation of exocytosis and cell polarity: Yeast as a model for animal cells

Brennwald, P., & Rossi, G. (2007) · FEBS Letters · doi:10.1016/j.febslet.2007.03.043 · Cited by 62 · see citing works

Yeast-to-Hyphal Transition Triggers Formin-dependent Golgi Localization to the Growing Tip inCandida albicans

Rida, P. C. G., Nishikawa, A., Won, G. Y., & Dean, N. (2006) · Molecular Biology of the Cell · doi:10.1091/mbc.e06-02-0143 · Cited by 59 · see citing works

Bicarbonate-mediated social communication stimulates meiosis and sporulation ofSaccharomyces cerevisiae

Ohkuni, K., Hayashi, M., & Yamashita, I. (1998) · Yeast · doi:10.1002/(sici)1097-0061(199805)14:7 · Cited by 57 · see citing works

Control of filamentous fungal cell shape by septins and formins

Gladfelter, A. S. (2006) · Nature Reviews Microbiology · doi:10.1038/nrmicro1345 · Cited by 56 · see citing works

The TIP1 gene of Saccharomyces cerevisiae encodes an 80 kDa cytoplasmic protein that interacts with the cytoplasmic domain of Sec20p.

Sweet, D. J., & Pelham, H. R. B. (1993) · The EMBO Journal · doi:10.1002/j.1460-2075.1993.tb05944.x · Cited by 55 · see citing works

Candida albicans VPS1 contributes to protease secretion, filamentation, and biofilm formation

Bernardo, S. M., Khalique, Z., Kot, J., Jones, J. K., & Lee, S. A. (2008) · Fungal Genetics and Biology · doi:10.1016/j.fgb.2008.01.001 · Cited by 53 · see citing works

Evidence for a nuclear passage of nascent polypeptide-associated complex subunits in yeast

Franke, J., Reimann, B., Hartmann, E., Köhler, M., & Wiedmann, B. (2001) · Journal of Cell Science · doi:10.1242/jcs.114.14.2641 · Cited by 52 · see citing works

Secretion of N-glycosylated interleukin-1 beta in Saccharomyces cerevisiae using a leader peptide from Candida albicans. Effect of N-linked glycosylation on biological activity

Livi, G. P., Lillquist, J. S., Miles, L. M., Ferrara, A., Sathe, G. M., Simon, P. L., Meyers, C. A., Gorman, J. A., & Young, P. R. (1991) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)98622-9 · Cited by 51 · see citing works

N-Myristoylation of Arf proteins in Candida albicans: an in vivo assay for evaluating antifungal inhibitors of myristoyl-CoA:protein N-myristoyltransferase

Lodge, J. K., Jackson-Machelski, E., Devadas, B., Zupec, M. E., Getman, D. P., Kishore, N. S., Freeman, S. K., McWherter, C. A., Sikorski, J. A., & Gordon, J. I. (1997) · Microbiology · doi:10.1099/00221287-143-2-357 · Cited by 47 · see citing works

Candida albicans Rho-Type GTPase-Encoding Genes Required for Polarized Cell Growth and Cell Separation

Dünkler, A., & Wendland, J. (2007) · Eukaryotic Cell · doi:10.1128/ec.00201-06 · Cited by 46 · see citing works

Cdc42p GTPase Regulates the Budded-to-Hyphal-Form Transition and Expression of Hypha-Specific Transcripts in Candida albicans

vandenBerg, A. L., Ibrahim, A. S., Edwards, J. E., Toenjes, K. A., & Johnson, D. I. (2004) · Eukaryotic Cell · doi:10.1128/ec.3.3.724-734.2004 · Cited by 46 · see citing works

Cloning of Candida albicans SEC14 Gene Homologue Coding for a Putative Essential Function

Monteoliva, L., Sánchez, M., Plá, J., Gil, C., & Nombela, C. (1996) · Yeast · doi:10.1002/(sici)1097-0061(19960915)12:11 · Cited by 43 · see citing works

Interactions between Spc2p and Other Components of the Endoplasmic Reticulum Translocation Sites of the YeastSaccharomyces cerevisiae

Antonin, W., Meyer, H., & Hartmann, E. (2000) · Journal of Biological Chemistry · doi:10.1074/jbc.m006126200 · Cited by 40 · see citing works

Overexpression of a Dominant-Negative Allele of SEC4 Inhibits Growth and Protein Secretion in Candida albicans

Mao, Y., Kalb, V. F., & Wong, B. (1999) · Journal of Bacteriology · doi:10.1128/jb.181.23.7235-7242.1999 · Cited by 40 · see citing works

The nascent polypeptide‐associated complex (NAC) of yeast functions in the targeting process of ribosomes to the ER membrane

Wiedmann, B., & Prehn, S. (1999) · FEBS Letters · doi:10.1016/s0014-5793(99)01118-7 · Cited by 36 · see citing works

Yarrowia lipolytica vesicle-mediated protein transport pathways

Swennen, D., & Beckerich, J.-M. (2007) · BMC Evolutionary Biology · doi:10.1186/1471-2148-7-219 · Cited by 32 · see citing works

Isolation of Pichia pastoris genes involved in ER‐to‐Golgi transport

Payne, W. E., Kaiser, C. A., Bevis, B. J., Soderholm, J., Fu, D., Sears, I. B., & Glick, B. S. (2000) · Yeast · doi:10.1002/1097-0061(200008)16:11 · Cited by 32 · see citing works

Functional characterization of the Candida albicans homologue of secretion‐associated and Ras‐related (Sar1) protein

Jiang, L., Lee, C., & Shen, S. (2002) · Yeast · doi:10.1002/yea.842 · Cited by 27 · see citing works

Use of green fluorescent protein fusions to analyse the N‐ and C‐terminal signal peptides of GPI‐anchored cell wall proteins in Candida albicans

Mao, Y., Zhang, Z., & Wong, B. (2003) · Molecular Microbiology · doi:10.1046/j.1365-2958.2003.03794.x · Cited by 27 · see citing works

Large-Scale Identification of Putative Exported Proteins in Candida albicans by Genetic Selection

Monteoliva, L., Matas, M., Gil, C., Nombela, C., & Plá, J. (2002) · Eukaryotic Cell · doi:10.1128/ec.1.4.514-525.2002 · Cited by 26 · see citing works

Pmt-Mediated O Mannosylation Stabilizes an Essential Component of the Secretory Apparatus, Sec20p, in Candida albicans

Weber, Y., Prill, S. K. ‐., & Ernst, J. F. (2004) · Eukaryotic Cell · doi:10.1128/ec.3.5.1164-1168.2004 · Cited by 26 · see citing works

Overexpression of a dominant-negative allele of YPT1 inhibits growth and aspartyl protease secretion in Candida albicans The GenBank accession number for the C. albicans YPT1 sequence reported in this paper is AF330211.

Lee, S. A., Mao, Y., Zhang, Z., & Wong, B. (2001) · Microbiology · doi:10.1099/00221287-147-7-1961 · Cited by 25 · see citing works

Cloning and characterization of the gene encoding the ADP-ribosylation factor in Candida albicans

Denich, K., Malloy, P. J., & Feldman, D. (1992) · Gene · doi:10.1016/0378-1119(92)90455-x · Cited by 23 · see citing works

Candida albicans RHO1is required for cell viability in vitro and in vivo

Smith, S. E., Csank, C., Reyes, G. H., Ghannoum, M. A., & Berlin, V. (2002) · FEMS Yeast Research · doi:10.1111/j.1567-1364.2002.tb00075.x · Cited by 22 · see citing works

Cloning and characterization of the SEC18 gene from Candida albicans

Nieto, A., Sentandreu, R., Agudo, L. D. C., & Sanz, P. (1993) · Yeast · doi:10.1002/yea.320090808 · Cited by 22 · see citing works

A functional analysis of theCandida albicanshomolog ofSaccharomyces cerevisiae VPS4

Lee, S. A., Jones, J. K., Khalique, Z., Kot, J., Alba, M., Bernardo, S. M., Seghal, A., & Wong, B. (2007) · FEMS Yeast Research · doi:10.1111/j.1567-1364.2007.00253.x · Cited by 21 · see citing works

Divergence of Eukaryotic Secretory Components: the Candida albicans Homolog of the Saccharomyces cerevisiae Sec20 Protein Is N Terminally Truncated, and Its Levels Determine Antifungal Drug Resistance and Growth

Weber, Y. G., Santore, U. J., Ernst, J. F., & Swoboda, R. (2001) · Journal of Bacteriology · doi:10.1128/jb.183.1.46-54.2001 · Cited by 17 · see citing works

Two transcripts, differing at their 3′ ends, are produced from the Candida albicans SEC14 gene

Riggle, P. J., Slobodkin, I. V., Brown, D. H., Hanson, M. P., Volkert, T. L., & Kumamoto, C. A. (1997) · Microbiology · doi:10.1099/00221287-143-11-3527 · Cited by 15 · see citing works

Brefeldin A blocks an early stage of protein transport in Candida albicans

Arioka, M., Hirata, A., Takatsuki, A., & Yamasaki, M. (1991) · Journal of General Microbiology · doi:10.1099/00221287-137-6-1253 · Cited by 15 · see citing works

Phosphatidylcholine transfer activity of yeast Sec14p is not essential for its function in vivo

Tahotná, D., Holič, R., Poloncová, K., Balážová, M., & Griač, P. (2006) · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids · doi:10.1016/j.bbalip.2006.11.002 · Cited by 10 · see citing works

Analysis of heterologous expression of Candida albicans SEC61 gene reveals differences in Sec61p homologues related to species-specific functionality

Arranz, J. M. D. L. R., Ruiz, T., Fonzi, W. A., & Rodríguez, L. (2004) · Fungal Genetics and Biology · doi:10.1016/j.fgb.2004.07.004 · Cited by 10 · see citing works

Identification and characterization of a Jem1p ortholog of Candida albicans: dissection of Jem1p functions in karyogamy and protein quality control in Saccharomyces cerevisiae

Makio, T., Nishikawa, S., Nakayama, T., Nagai, H., & Endo, T. (2008) · Genes to Cells · doi:10.1111/j.1365-2443.2008.01223.x · Cited by 9 · see citing works

Intracellular trafficking of fluorescently tagged proteins associated with pathogenesis inCandida albicans

Lee, S. A., Khalique, Z., Gale, C. A., & Wong, B. (2005) · Medical Mycology · doi:10.1080/13693780400013340 · Cited by 7 · see citing works

Deletion analysis of yeast Sec65p reveals a central domain that is sufficient for function in vivo

Régnacq, M., Hewitt, E. W., Allen, J., Rosamond, J., & Stirling, C. J. (1998) · Molecular Microbiology · doi:10.1046/j.1365-2958.1998.00969.x · Cited by 7 · see citing works

Sec20p-interacting proteins (Tip20p, Ufe1p) in the retrograde secretory pathway of the fungal pathogen Candida albicans

Weber, Y. G., Swoboda, R., & Ernst, J. F. (2002) · Molecular Genetics and Genomics · doi:10.1007/s00438-002-0777-z · Cited by 6 · see citing works

Characterization of Candida albicans orthologue of the Saccharomyces cerevisiae signal‐peptidase‐subunit encoding gene SPC3

Arranz, J. M. D. L. R., González, J. M., Gutiérrez, F., Ruíz, T., & Rodríguez, L. (2004) · Yeast · doi:10.1002/yea.1137 · Cited by 6 · see citing works

Gene order in a 10 275 bp fragment of Yarrowia lipolytica , including adjacent YlURA5 and YlSEC65 genes conserved in four yeast species

Sánchez, M., & Domínguez, Á. (2001) · Yeast · doi:10.1002/yea.735 · Cited by 3 · see citing works

The dental plaque biofilm matrix

Jakubovics, N. S., Goodman, S. D., Mashburn‐Warren, L., Stafford, G. P., & Cieplik, F. (2021) · Periodontology 2000 · doi:10.1111/prd.12361 · Cited by 488 · see citing works

The secretory pathway: exploring yeast diversity

Delic, M., Valli, M., Graf, A. B., Pfeffer, M., Mattanovich, D., & Gasser, B. (2013) · FEMS Microbiology Reviews · doi:10.1111/1574-6976.12020 · Cited by 254 · see citing works

Proteomics Unravels Extracellular Vesicles as Carriers of Classical Cytoplasmic Proteins in Candida albicans

Gil-Bona, A., Llama‐Palacios, A., Parra‐Giraldo, C. M., Vivanco, F., Nombela, C., Monteoliva, L., & Gil, C. (2014) · Journal of Proteome Research · doi:10.1021/pr5007944 · Cited by 151 · see citing works

Comparative analysis of secretomes in basidiomycete fungi

Alfaro, M., Oguiza, J. A., Ramı́rez, L., & Pisabarro, A. G. (2014) · Journal of Proteomics · doi:10.1016/j.jprot.2014.03.001 · Cited by 113 · see citing works

Comparative and transcriptional analysis of the predicted secretome in the lignocellulose‐degrading basidiomycete fungus Pleurotus ostreatus

Alfaro, M., Castanera, R., Lavín, J. L., Grigoriev, I. V., Oguiza, J. A., Ramı́rez, L., & Pisabarro, A. G. (2016) · Environmental Microbiology · doi:10.1111/1462-2920.13360 · Cited by 85 · see citing works

Lipid Biosynthetic Genes Affect Candida albicans Extracellular Vesicle Morphology, Cargo, and Immunostimulatory Properties

Wolf, J. M., Espadas, J., Luque-Garcia, J. L., Reynolds, T. B., & Casadevall, A. (2015) · Eukaryotic Cell · doi:10.1128/ec.00054-15 · Cited by 82 · see citing works

Phagosomal Neutralization by the Fungal Pathogen Candida albicans Induces Macrophage Pyroptosis

Vylkova, S., & Lorenz, M. C. (2016) · Infection and Immunity · doi:10.1128/iai.00832-16 · Cited by 75 · see citing works

Beyond the wall:Candida albicanssecret(e)s to survive

Sorgo, A. G., Heilmann, C. J., Brul, S., de Koster, C. G., & Klis, F. M. (2012) · FEMS Microbiology Letters · doi:10.1111/1574-6968.12049 · Cited by 72 · see citing works

SECRETOOL: integrated secretome analysis tool for fungi

Cortázar, A. R., Aransay, A. M., Alfaro, M., Oguiza, J. A., & Lavín, J. L. (2013) · Amino Acids · doi:10.1007/s00726-013-1649-z · Cited by 61 · see citing works

The external face of Candida albicans : A proteomic view of the cell surface and the extracellular environment

Gil-Bona, A., Amador-García, A., Gil, C., & Monteoliva, L. (2017) · Journal of Proteomics · doi:10.1016/j.jprot.2017.12.002 · Cited by 61 · see citing works

The Role of Secretory Pathways in Candida albicans Pathogenesis

Rollenhagen, C., Mamtani, S. S., Ma, D., Dixit, R., Eszterhas, S. K., & Lee, S. A. (2020) · Journal of Fungi · doi:10.3390/jof6010026 · Cited by 32 · see citing works

A comparative analysis of protein virulence factors released via extracellular vesicles in two Candida albicans strains cultivated in a nutrient-limited medium.

Konečná, K., Klimentova, J., Benada, O., Němečková, I., Janďourek, O., Jílek, P., & Vejsová, M. (2019) · Microbial Pathogenesis · doi:10.1016/j.micpath.2019.103666 · Cited by 23 · see citing works

Aliphatic fatty acids and esters: Inhibition of growth and exoenzyme production of Candida, and their cytotoxicity in vitro

Souza, J. L. S., da Silva, A. F., Carvalho, P. H. D. A., Pacheco, B. S., de Pereira, C. M. P., & Lund, R. G. (2014) · Archives of Oral Biology · doi:10.1016/j.archoralbio.2014.05.017 · Cited by 20 · see citing works

The Candida albicans Kar2 protein is essential and functions during the translocation of proteins into the endoplasmic reticulum

Morrow, M. W., Janke, M. R., Lund, K., Morrison, E. P., & Paulson, B. A. (2010) · Current Genetics · doi:10.1007/s00294-010-0323-1 · Cited by 12 · see citing works

(7-Chloroquinolin-4-yl)arylhydrazones: Candida albicansenzymatic repression and cytotoxicity evaluation, Part 2

Carvalho, P. H. D. A., Duval, A. R., Leite, F. R. M., Nedel, F., Cunico, W. J., & Lund, R. G. (2015) · Journal of Enzyme Inhibition and Medicinal Chemistry · doi:10.3109/14756366.2015.1010527 · Cited by 10 · see citing works

Quorum-driven microbial consortium for Bioplastic production from agro-waste

Crespo-Roche, D., Herráez, M., Guerrero-Flores, J., Martı́nez, M. J., Louie, K., Northen, T. R., Prieto, A., & Barriuso, J. (2025) · ACS Sustainable Chemistry & Engineering · doi:10.1021/acssuschemeng.5c05453 · Cited by 8 · see citing works

The Secretory Pathway in the Filamentous Fungus Trichoderma

Hernández-Chávez, M. J., González-Hernández, R. J., Trujillo-Esquivel, J. E., Hernández-Cervantes, A., & Mora-Montes, H. M. (2014) · Elsevier eBooks · doi:10.1016/b978-0-444-59576-8.00009-6 · Cited by 8 · see citing works

Essential Functional Modules for Pathogenic and Defensive Mechanisms inCandida albicansInfections

Wang, Y., Tsai, I.-C., Lin, C., Hsieh, W., Lan, C., Chuang, Y., & Chen, B. (2014) · BioMed Research International · doi:10.1155/2014/136130 · Cited by 7 · see citing works

Candida albicans cDNA library screening reveals novel potential diagnostic targets for invasive candidiasis

Bregón-Villahoz, M., Menéndez-Manjón, P., Carrano, G., Díez, A., Arrieta-Aguirre, I., Fernandez-de-Larrinoa, Í., & Moragues, M. D. (2024) · Diagnostic Microbiology and Infectious Disease · doi:10.1016/j.diagmicrobio.2024.116311 · Cited by 5 · see citing works

The P-type calcium pump Spf1 regulates immune response by maintenance of the endoplasmic reticulum-plasma membrane contacts during Candida albicans systemic infection

Ji, Y., Chen, D., Shao, M., Liu, Z., Li, M., & Yu, Q. (2024) · Mycology&#58 An International Journal on Fungal Biology · doi:10.1080/21501203.2024.2409299 · Cited by 3 · see citing works

Antifungal Susceptibility, Exoenzyme Production and Cytotoxicity of Novel Oximes against Candida

Souza, J., Nedel, F., Ritter, M., Carvalho, P. H. D. A., de Pereira, C. M. P., & Lund, R. G. (2013) · Mycopathologia · doi:10.1007/s11046-013-9675-7 · Cited by 3 · see citing works

Current awareness on yeast

(2009) · Yeast · doi:10.1002/yea.1627

References

(2021) · Elsevier eBooks · doi:10.1016/b978-0-12-816983-4.00003-1

Candida albicans: Pathogenesis and Secretory Pathways

Afzelius, P., Proestos, C., & Behzadi, P. (2024) · IntechOpen eBooks · doi:10.5772/intechopen.1005420

Les jonctions serrées des entérocytes comme cible pour la translocation de Candida albicans à travers la barrière intestinale

Paradis, T. (2021) · theses.fr (ABES) · doi:10.70675/cafcd288za23dz457ezb0ddz92235b0c3f89

The Role of Secretory Pathways in Candida albicans Pathogenesis

Rollenhagen, C., Mamtani, S. S., Ma, D., Dixit, R., Eszterhas, S. K., & Lee, S. A. (2020) · Journal of Fungi · doi:10.3390/jof6010026 · Cited by 32 · see citing works

Secreted proteins of Candida albicans

Hrušková‐Heidingsfeldová, O. (2008) · Frontiers in bioscience · doi:10.2741/3224 · Cited by 46 · see citing works

Candida albicans: Pathogenesis and Secretory Pathways

Afzelius, P., Proestos, C., & Behzadi, P. (2024) · IntechOpen eBooks · doi:10.5772/intechopen.1005420

Hyphae-specific genes HGC1, ALS3, HWP1, and ECE1 and relevant signaling pathways in Candida albicans

Fan, Y., He, H., Dong, Y., & Pan, H. (2013) · Mycopathologia · doi:10.1007/s11046-013-9684-6 · Cited by 93 · see citing works

Intracellular trafficking of fluorescently tagged proteins associated with pathogenesis inCandida albicans

Lee, S. A., Khalique, Z., Gale, C. A., & Wong, B. (2005) · Medical Mycology · doi:10.1080/13693780400013340 · Cited by 7 · see citing works