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Cited by 140Psychosomatic Disorders and Their TreatmentsPosttraumatic Stress Disorder ResearchChild Abuse and Trauma

The DOI matches its Crossref record; 45 of the 46 references it cites were found in a registry or an index.

Amygdala and hippocampal volumes and cognition in adult survivors of childhood abuse with dissociative disorders

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Weniger, G., Lange, C., Sachsse, U., Irle, E.·2008·Acta Psychiatrica Scandinavica
DOI 10.1111/j.1600-0447.2008.01246.x
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Abstract

Objective: Trauma‐exposed individuals with post‐traumatic stress disorder (PTSD) display reduced amygdala and hippocampal size and impaired cognition. However, studies on trauma‐exposed individuals with dissociative amnesia (DA) or dissociative identity disorder (DID) are lacking. Method: Twenty‐three young women who had experienced severe childhood sexual/physical abuse, diagnosed with DA/DID or PTSD, and 25 healthy control subjects were subjected to 3D structural magnetic resonance imaging of amygdala and hippocampus and a clinical and neuropsychological investigation. Results: Compared with controls, trauma‐exposed subjects with PTSD ( n = 10) displayed significantly reduced amygdala and hippocampal size and significantly impaired cognition. By contrast, trauma‐exposed subjects with DA or DID ( n = 13) displayed normal amygdala and hippocampal size and normal cognition. Conclusion: We report for the first time volumetric results in subjects with DA/DID without PTSD as comorbid diagnosis. Our results indicate preserved amygdala and hippocampal size and preserved cognition in subjects with these disorders.

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Crossref · 10.1111/j.1600-0447.2008.01246.x

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Research works printed but not linked: 6

  1. Wittchen HU, 1997, Strukturiertes Klinisches Interview für DSM‐IV
  2. Gast U, 2000, Strukturiertes Klinisches Interview für DSM‐IV
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Metadata

Authors
Weniger, G., Lange, C., Sachsse, U., & Irle, E.
Affiliations
  • University of Zurich (CH)
  • University of Göttingen (DE)
Corresponding author
Irle, E.
ORCID
Venue
Acta Psychiatrica Scandinavica
Publisher
Wiley
Published
2008-09-10
Volume
118
Issue
4
Pages
281-290
ISSN
  • 0001-690X (ISSN-L)
  • 1600-0447
DOI
10.1111/j.1600-0447.2008.01246.x
OpenAlex
W2046297778
Cited by
140
References
46
Citations by year
2026: 2 · 2025: 4 · 2024: 4 · 2023: 4 · 2022: 5 · 2021: 9 · 2020: 7 · 2019: 4 · 2018: 6 · 2017: 8 · 2016: 15 · 2015: 14 · 2014: 12 · 2013: 8 · 2012: 15
FWCI
5.37
Type
journal article
Language
en
Open access
Licence
onlinelibrary.wiley.com/termsAndConditions#vor (vor)
Locations
  • Acta Psychiatrica Scandinavica (publishedVersion)
  • PubMed (publishedVersion)
  • Zurich Open Repository and Archive (University of Zurich) (acceptedVersion)
  • Zurich Open Repository and Archive (University of Zurich) (submittedVersion)
  • Zurich Open Repository and Archive (University of Zurich)
Funders
Deutsche Forschungsgemeinschaft
Topics
  • Health Sciences › Medicine › Psychiatry and Mental health › Psychosomatic Disorders and Their Treatments
  • Social Sciences › Psychology › Clinical Psychology › Posttraumatic Stress Disorder Research
  • Social Sciences › Psychology › Clinical Psychology › Child Abuse and Trauma
Keywords
amygdala volume, hippocampal volume, dissociative amnesia, dissociative identity disorder, child sexual abuse, child physical abuse, post-traumatic stress disorder, dissociative disorders, cognitive impairment, brain structure, trauma exposure
MeSH terms
Adult, Amygdala, Cognition, Cognition Disorders, Dissociative Disorders, Female, Hippocampus, Humans, Magnetic Resonance Imaging, Neuropsychological Tests, Organ Size, Stress Disorders, Post-Traumatic, Imaging, Three-Dimensional, Adult Survivors of Child Abuse

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