Mediators of the association between depression and role functioning

Buist‐Bouwman, M. A.; Ormel, J.; De Graaf, R.; De Jonge, P.; Van Sonderen, E.; Alonso, J.; Bruffaerts, R.; Vollebergh, W. A. M.; the ESEMeD/MHEDEA 2000 investigators

doi:10.1111/j.1600-0447.2008.01285.x

Cited by 127Mental Health Treatment and AccessAnxiety, Depression, Psychometrics, Treatment, Cognitive ProcessesAging, Health, and Disability

Mediators of the association between depression and role functioning

Open access

Buist‐Bouwman, M. A., Ormel, J., De Graaf, R., De Jonge, P., Van Sonderen, E., Alonso, J., Bruffaerts, R., Vollebergh, W. A. M. +1 more·2008·Acta Psychiatrica Scandinavica

DOI 10.1111/j.1600-0447.2008.01285.xPMC PMC3659780

Open this paper in CoChat — free account Open PDF

Abstract

Objective: While the adverse effect of Major Depressive Episode on role functioning is well established, the exact pathways remain unclear. Method: Data from The European Study of the Epidemiology of Mental Disorders, a cross‐sectional survey including 21 425 adults from six European countries, were used to assess 12‐month depression (Composite International Diagnostic Interview), activity limitations and role functioning in the past 30 days (Disability Assessment Schedule). An a priori model based on the World Health Organization’s International Classification of Functioning, Disability and Health was designed and a structural equation model for categorical and ordinal data was used (MPlus) to estimate the extent to which six limitations mediated the association between depression and role functioning. Results: The unadjusted association between depression and role functioning was strong (0.43; SE = 0.04). In the best‐fitting model, only concentration and attention problems and embarrassment mediated a significant amount of association (direct effect dropped to 0.17; SE = 0.10, which was no longer significant). Conclusions: Targeting cognition and embarrassment in treatment could help reduce depression‐associated role disfunctioning.

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Integrity signals

Registry

Crossref · 10.1111/j.1600-0447.2008.01285.x

Cites

40 of 40 references verified0 citation errors · 0 not checkable

Statistics

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

In patients with major depressive disorder, cognitive complaint is correlated more closely with depressive symptoms and psychosocial functioning than is objective cognitive impairment.
“CC in MDD patients is correlated more closely with not only depressive symptoms, but also psychosocial functioning compared to objective cognitive impairment [19-23].”
From Acute Efficacy and Safety of Escitalopram Versus Desvenlafaxine and Vortioxetine in the Treatment of Depression With Cognitive Complaint: A Rater-Blinded Randomized Comparative Study (2022) · cites this paper as [21]
The Methods (page unavailable) measure reported cognitive difficulties, and the Results and Discussion (page unavailable) link those difficulties to major depressive episodes and role functioning. The paper does not compare cognitive complaints with objective cognitive impairment or show that complaints correlate more closely with depressive-symptom severity. Its sample is a population survey, not specifically patients with major depressive disorder. (LLM, conf=0.87)
Experimental — accuracy not yet measured
Cognitive deficits may impede functional recovery, including workforce performance, in patients with major depressive disorder.
“Cognitive deficits may also impede functional recovery, including workforce performance, in patients with MDD.”
From Cognitive remission: a novel objective for the treatment of major depression? (2016) · cites this paper as [15]
Several lines of evidence suggest that cognitive dysfunction is an important mediator of functioning, including workforce performance, in major depressive disorder.
“Several lines of evidence suggest that cognitive dysfunction is an important mediator of functioning, including workforce performance, in MDD [14–16].”
From Cognitive remission: a novel objective for the treatment of major depression? (2016) · cites this paper as [15]
Cognitive deficits and embarrassment account for half of the association between a major depressive episode and work loss.
“Data from The European Study of the Epidemiology of Mental Disorders, a cross-sectional survey including 21,425 adults from six European countries, reported that cognitive deficits and embarrassment (i.e. stigma) account for half of the association between a MDE and work loss [15].”
From Cognitive remission: a novel objective for the treatment of major depression? (2016) · cites this paper as [15]
Cognitive symptoms have been associated with poor occupational functioning and unemployment, work-related disability, and adverse psychosocial outcomes.
“Cognitive symptoms have also been associated with poor occupational functioning [18] and unemployment [19], work-related disability, and adverse psychosocial outcomes [20-22].”
From Wearable technology for high-frequency cognitive and mood assessment in major depressive disorder: longitudinal observational study (2019) · cites this paper as [22]

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

A 12-Item Short-Form Health Survey: Construction of Scales and Preliminary Tests of Reliability and Validity
WARE, J. E., KOSINSKI, M., & KELLER, S. D. (1996) · Medical Care · doi:10.1097/00005650-199603000-00003 · Cited by 17,392 · see citing works
Selective Cortical Undercutting As a Means of Modifying and Studying Frontal Lobe Function in Man
Scoville, W. B. (1949) · Journal of neurosurgery · doi:10.3171/jns.1949.6.1.0065 · Cited by 7,373 · see citing works
The World Mental Health (WMH) Survey Initiative version of the World Health Organization (WHO) Composite International Diagnostic Interview (CIDI)
Kessler, R. C., & Üstün, T. B. (2004) · International Journal of Methods in Psychiatric Research · doi:10.1002/mpr.168 · Cited by 4,771 · see citing works
Species Richness of Parasite Assemblages: Evolution and Patterns
Poulin, R. (1997) · Annual Review of Ecology and Systematics · doi:10.1146/annurev.ecolsys.28.1.341 · Cited by 3,500 · see citing works
International Classification of Functioning, Disability and Health (ICF) 2001
Jiménez-Buñuales, M. T., Diego, P. G., & Moreno, J. M. ª. M. (2002) · Revista Española de Salud Pública · doi:10.1590/s1135-57272002000400002 · Cited by 3,267 · see citing works
Reliability and validity studies of the WHO-Composite International Diagnostic Interview (CIDI): A critical review
Wittchen, H.-U. (1994) · Journal of Psychiatric Research · doi:10.1016/0022-3956(94)90036-1 · Cited by 2,348 · see citing works
How Do Risk Factors Work Together? Mediators, Moderators, and Independent, Overlapping, and Proxy Risk Factors
Kraemer, H. C., Stice, E., Kazdin, A., Offord, D., & Kupfer, D. (2001) · American Journal of Psychiatry · doi:10.1176/appi.ajp.158.6.848 · Cited by 1,712 · see citing works
Depression, Disability Days, and Days Lost From Work in a Prospective Epidemiologic Survey
Broadhead, W. E. (1990) · JAMA · doi:10.1001/jama.1990.03450190056028 · Cited by 1,232 · see citing works
The epidemiology of major depressive episodes: results from the International Consortium of Psychiatric Epidemiology (ICPE) Surveys
Andrade, L., Caraveo‐anduaga, J. J., Berglund, P., Bijl, R. V., Graaf, R. D., Vollebergh, W., Dragomirecka, E., Kohn, R., Keller, M., Kessler, R. C., et al. (2003) · International Journal of Methods in Psychiatric Research · doi:10.1002/mpr.138 · Cited by 1,068 · see citing works
Self-citation
Economic burden of depression
Greenberg, P. E., Stiglin, L. E., Finkelstein, S. N., & Berndt, E. R. (1994) · PharmacoResources · doi:10.1007/bf03289581 · Cited by 974 · see citing works
Stigma as a Barrier to Recovery: Perceived Stigma and Patient-Rated Severity of Illness as Predictors of Antidepressant Drug Adherence
Sirey, J. A., Bruce, M. L., Alexopoulos, G. S., Perlick, D. A., Friedman, S. J., & Meyers, B. S. (2001) · Psychiatric Services · doi:10.1176/appi.ps.52.12.1615 · Cited by 796 · see citing works
Perceived Stigma as a Predictor of Treatment Discontinuation in Young and Older Outpatients With Depression
Sirey, J. A., BRUCE, M. L., Alexopoulos, G. S., PERLICK, D. A., Raue, P. J., Friedman, S. J., & Meyers, B. S. (2001) · American Journal of Psychiatry · doi:10.1176/appi.ajp.158.3.479 · Cited by 779 · see citing works
Childhood abuse as a risk factor for psychotic experiences
Janssen, I., Krabbendam, L., Bak, M., Hanssen, M., Vollebergh, W., de Graaf, R., & van Os, J. (2004) · Acta Psychiatrica Scandinavica · doi:10.1046/j.0001-690x.2003.00217.x · Cited by 762 · see citing works
Self-citation
Service utilization and social morbidity associated with depressive symptoms in the community
Johnson, J. (1992) · JAMA: The Journal of the American Medical Association · doi:10.1001/jama.1992.03480110054033 · Cited by 726 · see citing works
The impact of psychiatric disorders on work loss days
Kessler, R. C., & Frank, R. G. (1997) · Psychological Medicine · doi:10.1017/s0033291797004807 · Cited by 716 · see citing works
Psychosocial Disability During the Long-term Course of Unipolar Major Depressive Disorder
Judd, L. L., Akiskal, H. S., Zeller, P. J., Paulus, M., Leon, A. C., Maser, J. D., Endicott, J., Coryell, W., Kunovac, J. L., Mueller, T. I., et al. (2000) · Archives of General Psychiatry · doi:10.1001/archpsyc.57.4.375 · Cited by 593 · see citing works
Disability and quality of life impact of mental disorders in Europe: results from the European Study of the Epidemiology of Mental Disorders (ESEMeD) project
The ESEMeD/MHEDEA 2000 investigators, Alonso, J., Angermeyer, M. C., Bernert, S., Bruffaerts, R., Brugha, T. S., Bryson, H., de Girolamo, G., de Graaf, R., Demyttenaere, K., et al. (2004) · Acta Psychiatrica Scandinavica · doi:10.1111/j.1600-0047.2004.00329.x · Cited by 581 · see citing works
Self-citation
Rehabilitation of brain damage: Brain plasticity and principles of guided recovery.
Robertson, I. H., & Murre, J. M. J. (1999) · Psychological Bulletin · doi:10.1037/0033-2909.125.5.544 · Cited by 507 · see citing works
The economic burden of depression
Stoudemire, A., Frank, R. W., Hedemark, N., Kamlet, M. S., & Blazer, D. G. (1986) · General Hospital Psychiatry · doi:10.1016/0163-8343(86)90018-6 · Cited by 480 · see citing works
Service utilization and social morbidity associated with depressive symptoms in the community
Johnson, J. O. (1992) · JAMA · doi:10.1001/jama.267.11.1478 · Cited by 239 · see citing works
Sampling and methods of the European Study of the Epidemiology of Mental Disorders (ESEMeD) project
The ESEMeD/MHEDEA 2000 investigators, Alonso, J., Angermeyer, M. C., Bernert, S., Bruffaerts, R., Brugha, T. S., Bryson, H., de Girolamo, G., de Graaf, R., Demyttenaere, K., et al. (2004) · Acta Psychiatrica Scandinavica · doi:10.1111/j.1600-0047.2004.00326 · Cited by 211 · see citing works
Self-citation
Stigma and depression among primary care patients
Roeloffs, C., Sherbourne, C., Unützer, J., Fink, A., Tang, L., & Wells, K. B. (2003) · General Hospital Psychiatry · doi:10.1016/s0163-8343(03)00066-5 · Cited by 208 · see citing works
The economic impact of depression in a workplace
Conti, D. J., & Burton, W. N. (1995) · Journal of Safety Research · doi:10.1016/0022-4375(95)98077-d · Cited by 202 · see citing works
Sickness absence for psychiatric illness: The Whitehall II study
Stansfeld, S. A., Feeney, A., Head, J. A., Canner, R., North, F. M., & Marmot, M. G. (1995) · Social Science & Medicine · doi:10.1016/0277-9536(94)e0064-y · Cited by 190 · see citing works
A general population comparison of the Composite International Diagnostic Interview (CIDI) and the Schedules for Clinical Assessment in Neuropsychiatry (SCAN)
BRUGHA, T. S., JENKINS, R., TAUB, N., MELTZER, H., & BEBBINGTON, P. E. (2001) · Psychological Medicine · doi:10.1017/s0033291701004184 · Cited by 171 · see citing works
Functional disability of mental disorders and comparison with physical disorders: a study among the general population of six European countries
Buist‐Bouwman, M. A., de Graaf, R., Vollebergh, W., Alonso, J., Bruffaerts, R., Ormel, J., & the ESEMeD/MHEDEA 2000 investigators (2005) · Acta Psychiatrica Scandinavica · doi:10.1111/j.1600-0447.2005.00684.x · Cited by 167 · see citing works
Self-citation
Psychosocial Disability Before, During, and After a Major DepressiveEpisode: A 3-Wave Population-Based Study of State, Scar, and Trait Effects
Ormel, J., Oldehinkel, A. J., Nolen, W. A., & Vollebergh, W. (2004) · Archives of General Psychiatry · doi:10.1001/archpsyc.61.4.387 · Cited by 154 · see citing works
Self-citation
Emotional disability days: prevalence and predictors.
Kouzis, A. C., & Eaton, W. W. (1994) · American Journal of Public Health · doi:10.2105/ajph.84.8.1304 · Cited by 121 · see citing works
Perceived Stigma and Patient-Rated Severity of Illness as Predictors of Antidepressant Drug Adherence
Sirey, J. A., BRUCE, M. L., Alexopoulos, S., PERLICK, D. A., Friedman, S., & Meyers, S. L. (2001) · Cited by 118 · see citing works
The European Study of the Epidemiology of Mental Disorders (ESEMeD/MHEDEA 2000) project: rationale and methods
Alonso, J., Ferrer, M., Romera, B., Vilagut, G., Angermeyer, M. C., Bernert, S., Brugha, T. S., Taub, N. A., Mccolgen, Z., de Girolamo, G., et al. (2002) · International Journal of Methods in Psychiatric Research · doi:10.1002/mpr.123 · Cited by 111 · see citing works
Self-citation
The World Health Organization International Consorthm in Psychiatric Epidemiology (ICPE): initial work and future directions ‐ the NAPE Lecture 1998a
Kessler, R. C. (1999) · Acta Psychiatrica Scandinavica · doi:10.1111/j.1600-0447.1999.tb05378.x · Cited by 105 · see citing works
Neuropsychological functioning in major depression and responsiveness to selective serotonin reuptake inhibitors antidepressants
Kampf-Sherf, O. (2004) · Journal of Affective Disorders · doi:10.1016/j.jad.2004.02.006 · Cited by 76 · see citing works
Psychometric properties of the World Health Organization Disability Assessment Schedule used in the European Study of the Epidemiology of Mental Disorders
Buist‐Bouwman, M. A., Ormel, J., de Graaf, R., Vilagut, G., Alonso, J., van Sonderen, E., Vollebergh, W., & The ESEMeD/MHEDEA 2000 Investigators (2008) · International Journal of Methods in Psychiatric Research · doi:10.1002/mpr.261 · Cited by 63 · see citing works
Self-citation
Psychiatric Disability in Ontario
Goering, P. N., Lin, E. H. B., Campbell, D., Boyle, M. H., & Offord, D. R. (1996) · The Canadian Journal of Psychiatry · doi:10.1177/070674379604100924 · Cited by 63 · see citing works
Functioning after a major depressive episode: complete or incomplete recovery?
Buist‐Bouwman, M. A. (2004) · Journal of Affective Disorders · doi:10.1016/j.jad.2004.02.007 · Cited by 55 · see citing works
Self-citation
Stigma of depression – a personal view
Wolpert, L. (2001) · British Medical Bulletin · doi:10.1093/bmb/57.1.221 · Cited by 48 · see citing works
Psychopathology and the development of disability
Kouzis, A. C., & Eaton, W. W. (1997) · Social Psychiatry and Psychiatric Epidemiology · doi:10.1007/bf00788177 · Cited by 44 · see citing works
The neuropsychology of depression and its implications for cognitive therapy
Crews, W. D., & Harrison, D. W. (1995) · Neuropsychology Review · doi:10.1007/bf02208437 · Cited by 42 · see citing works
Cognitive neuroscience and brain rehabilitation: a promise kept
Robertson, I. H. (2002) · Journal of Neurology Neurosurgery & Psychiatry · doi:10.1136/jnnp.73.4.357 · Cited by 13 · see citing works
The European study of the epidemiology of mental disorders (ESEMedD) project: rationale and methods (vol 11, pg 55, 2002)
Alonso, J., Angermeyer, M. C., Brugha, S., de Girolamo, G., de Graaf, R., Demyttenaere, K., Gasquet, N. V., Haro, J. M., Katz, S. J., Kessler, R. C., et al. (2003) · University of Groningen research database (University of Groningen / Centre for Information Technology) · doi:10.1002/mpr.153 · Cited by 4 · see citing works

Flagged first, then by citations

1 of the 41 references couldn’t be matched to a known paper.

Sorted by citations

Cognitive function following a major depressive episode: a systematic review and meta-analysis
Semkovska, M., Quinlivan, L., O'Grady, T., Johnson, R., Collins, A., O'Connor, J., Knittle, H., Ahern, E., & Gload, T. (2019) · The Lancet Psychiatry · doi:10.1016/s2215-0366(19)30291-3 · Cited by 631 · see citing works
World Health Organization disability assessment schedule 2.0: An international systematic review
Federici, S., Bracalenti, M., Meloni, F., & Luciano, J. V. (2016) · Disability and Rehabilitation · doi:10.1080/09638288.2016.1223177 · Cited by 514 · see citing works
Cognitive Dysfunction in Major Depressive Disorder: Effects on Psychosocial Functioning and Implications for Treatment
Lam, R. W. M., Kennedy, S. H., McIntyre, R. S., & Khullar, A. (2014) · The Canadian Journal of Psychiatry · doi:10.1177/070674371405901206 · Cited by 444 · see citing works
A randomized, double-blind, placebo-controlled study of vortioxetine on cognitive function in depressed adults
McIntyre, R. S., Lophaven, S., & Olsen, C. K. (2014) · The International Journal of Neuropsychopharmacology · doi:10.1017/s1461145714000546 · Cited by 433 · see citing works
Cognitive Impairment in Major Depressive Disorder
Pan, Z., Park, C., Brietzke, E., Zuckerman, H., Rong, C., Mansur, R. B., Fus, D., Subramaniapillai, M., Lee, Y., & McIntyre, R. S. (2019) · CNS Spectrums · doi:10.1017/s1092852918001207 · Cited by 320 · see citing works
Severity of Depression and Magnitude of Productivity Loss
Beck, A., Crain, A. L., Solberg, L. I., Unutzer, J., Glasgow, R. E., Maciosek, M. V., & Whitebird, R. (2011) · The Annals of Family Medicine · doi:10.1370/afm.1260 · Cited by 290 · see citing works
Systematic literature review on ICF from 2001 to 2009: its use, implementation and operationalisation
Černiauskaitė, M., Quintas, R. M. M., Boldt, C., Raggi, A., Cieza, A., Bickenbach, J. E., & Leonardi, M. (2010) · Disability and Rehabilitation · doi:10.3109/09638288.2010.529235 · Cited by 287 · see citing works
Cigarette smoking and depression comorbidity: systematic review and proposed theoretical model
Mathew, A. R., Hogarth, L., Leventhal, A. M., Cook, J. W., & Hitsman, B. L. (2016) · Addiction · doi:10.1111/add.13604 · Cited by 277 · see citing works
The Role of Mental Health on Workplace Productivity: A Critical Review of the Literature
de Oliveira, C., Saka, M., Bone, L., & Jacobs, R. (2022) · Applied Health Economics and Health Policy · doi:10.1007/s40258-022-00761-w · Cited by 269 · see citing works
Cognitive remission: a novel objective for the treatment of major depression?
Bortolato, B., Miskowiak, K. W., Köhler, C. A., Maes, M., Fernandes, B. S., Berk, M., & Carvalho, A. F. (2016) · BMC Medicine · doi:10.1186/s12916-016-0560-3 · Cited by 252 · see citing works
Recognition and Treatment of Cognitive Dysfunction in Major Depressive Disorder
Zuckerman, H., Pan, Z., Park, C., Brietzke, E. M., Musial, N., Shariq, A. S., Iacobucci, M., Yim, S. J., Lui, L. M. W., Rong, C., et al. (2018) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2018.00655 · Cited by 256 · see citing works
A meta-analysis of the effects of antidepressants on cognitive functioning in depressed and non-depressed samples
Prado, C. E., Watt, S., & Crowe, S. F. (2018) · Neuropsychology Review · doi:10.1007/s11065-018-9369-5 · Cited by 188 · see citing works
Cognitive Deficits as a Mediator of Poor Occupational Function in Remitted Major Depressive Disorder Patients
Woo, Y. S., Rosenblat, J. D., Kakar, R., Bahk, W.-M., & McIntyre, R. S. (2016) · Clinical Psychopharmacology and Neuroscience · doi:10.9758/cpn.2016.14.1.1 · Cited by 183 · see citing works
The clinical relationship between cognitive impairment and psychosocial functioning in major depressive disorder: A systematic review
Cambridge, O. R., Knight, M. J., Mills, N. T., & Baune, B. T. (2018) · Psychiatry Research · doi:10.1016/j.psychres.2018.08.033 · Cited by 186 · see citing works
Cognitive dysfunction in major depressive disorder: a state-of-the-art clinical review
Bortolato, B., Carvalho, A., & McIntyre, R. (2015) · CNS & Neurological Disorders - Drug Targets · doi:10.2174/1871527313666141130203823 · Cited by 181 · see citing works
The impact of cognitive impairment on perceived workforce performance: Results from the International Mood Disorders Collaborative Project
McIntyre, R. S., Soczynska, J. K., Woldeyohannes, H. O., Alsuwaidan, M. T., Cha, D. S., Carvalho, A. F., Jerrell, J. M., Dale, R. M., Gallaugher, L. A., Muzina, D. J., et al. (2014) · Comprehensive Psychiatry · doi:10.1016/j.comppsych.2014.08.051 · Cited by 154 · see citing works
Cognitive dysfunction and work productivity in major depressive disorder
Clark, M., DiBenedetti, D. B., & Pérez, V. (2016) · Expert Review of Pharmacoeconomics & Outcomes Research · doi:10.1080/14737167.2016.1195688 · Cited by 127 · see citing works
Screening for cognitive dysfunction in unipolar depression: Validation and evaluation of objective and subjective tools
Ott, C. V., Bjertrup, A. J., Jensen, J. H., Ullum, H., Sjælland, R., Purdon, S. E., Vieta, E., Kessing, L. V., & Miskowiak, K. W. (2016) · Journal of Affective Disorders · doi:10.1016/j.jad.2015.10.059 · Cited by 128 · see citing works
The role of cognitive impairment in psychosocial functioning in remitted depression
Knight, M. J., Air, T., & Baune, B. T. (2018) · Journal of Affective Disorders · doi:10.1016/j.jad.2018.04.051 · Cited by 117 · see citing works
Cognitive Dysfunction in Depression – Pathophysiology and Novel Targets
Carvalho, A., Miskowiak, K., Hyphantis, T., Kohler, C., Alves, G., Bortolato, B., G. Sales, P., Machado-Vieira, R., Berk, M., & McIntyre, R. (2015) · CNS & Neurological Disorders - Drug Targets · doi:10.2174/1871527313666141130203627 · Cited by 107 · see citing works
Clinical characteristics associated with the discrepancy between subjective and objective cognitive impairment in depression
Petersen, J. Z., Porter, R. J., & Miskowiak, K. W. (2019) · Journal of Affective Disorders · doi:10.1016/j.jad.2018.12.105 · Cited by 98 · see citing works
Health related quality of life in recurrent depression: A comparison with a general population sample
ten Doesschate, M. C., Koeter, M. W. J., Bockting, C. L. H., & Schene, A. H. (2010) · Journal of Affective Disorders · doi:10.1016/j.jad.2009.04.026 · Cited by 91 · see citing works
Vortioxetine reduces BOLD signal during performance of the N-back working memory task: a randomised neuroimaging trial in remitted depressed patients and healthy controls
Smith, J. E. T., Browning, M. D., Conen, S., Smallman, R. P., Buchbjerg, J. K., Larsen, K. G., Olsen, C. K., Christensen, S. R., Dawson, G. R., Deakin, J. F. W., et al. (2017) · Molecular Psychiatry · doi:10.1038/mp.2017.104 · Cited by 90 · see citing works
Cognition in major depressive disorder: a ‘Systemically Important Functional Index’ (SIFI)
McIntyre, R. S., & Lee, Y. (2016) · Current Opinion in Psychiatry · doi:10.1097/yco.0000000000000221 · Cited by 85 · see citing works
Treating to target in major depressive disorder: response to remission to functional recovery
McIntyre, R. S., Lee, Y. L., & Mansur, R. B. (2015) · CNS Spectrums · doi:10.1017/s1092852915000826 · Cited by 83 · see citing works
Wearable technology for high-frequency cognitive and mood assessment in major depressive disorder: longitudinal observational study
Cormack, F., McCue, M., Taptiklis, N., Skirrow, C., Glazer, E., Panagopoulos, E., van Schaik, T. A., Fehnert, B., King, J., & Barnett, J. H. (2019) · JMIR Mental Health · doi:10.2196/12814 · Cited by 79 · see citing works
The effects of vortioxetine on cognitive performance in working patients with major depressive disorder: A short-term, randomized, double-blind, exploratory study
Baune, B. T., Sluth, L. B., & Olsen, C. K. (2017) · Journal of Affective Disorders · doi:10.1016/j.jad.2017.12.056 · Cited by 73 · see citing works
The glycine site of NMDA receptors: A target for cognitive enhancement in psychiatric disorders
Peyrovian, B., Rosenblat, J. D., Pan, Z., Iacobucci, M., Brietzke, E. M., & McIntyre, R. S. (2019) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2019.02.001 · Cited by 70 · see citing works
Cognitive Dysfunction in Major Depressive Disorder: Assessment, Impact, and Management
Chakrabarty, T., Hadjipavlou, G., & Lam, R. W. (2016) · Focus · doi:10.1176/appi.focus.20150043 · Cited by 84 · see citing works
Potential and Challenges for the Clinical Use of d-Serine As a Cognitive Enhancer
Guercio, G. D., & Panizzutti, R. (2018) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2018.00014 · Cited by 64 · see citing works
The effect of bupropion XL and escitalopram on memory and functional outcomes in adults with major depressive disorder: Results from a randomized controlled trial
Soczynska, J. K., Ravindran, L. N., Styra, R., McIntyre, R. S., Cyriac, A., Manierka, M. S., & Kennedy, S. H. (2014) · Psychiatry Research · doi:10.1016/j.psychres.2014.06.053 · Cited by 60 · see citing works
A randomized, double-blind, placebo-controlled, crossover trial evaluating the effect of intranasal insulin on cognition and mood in individuals with treatment-resistant major depressive disorder
Cha, D. S., Best, M. W., Bowie, C. R., Gallaugher, L. A., Woldeyohannes, H. O., Soczynska, J. K., Lewis, G. F., MacQUEEN, G. M., Sahakian, B. J., Kennedy, S. H., et al. (2016) · Journal of Affective Disorders · doi:10.1016/j.jad.2016.12.006 · Cited by 56 · see citing works
Cognitive impairment as measured by the THINC-integrated tool (THINC-it): Association with psychosocial function in major depressive disorder
Cha, D. S., Carmona, N. E., Subramaniapillai, M., Mansur, R. B., Lee, Y. L., Lee, J. H., Lee, J., Rosenblat, J. D., Shekotikhina, M., Park, C., et al. (2017) · Journal of Affective Disorders · doi:10.1016/j.jad.2017.06.036 · Cited by 53 · see citing works
Long-term functioning outcomes are predicted by cognitive symptoms in working patients with major depressive disorder treated with vortioxetine: results from the AtWoRC study
Chokka, P. R., Bougie, J. K., Proulx, J., Tvistholm, A. H., & Ettrup, A. (2019) · CNS Spectrums · doi:10.1017/s1092852919000786 · Cited by 55 · see citing works
Assessment in work productivity and the relationship with cognitive symptoms (AtWoRC): primary analysis from a Canadian open-label study of vortioxetine in patients with major depressive disorder (MDD)
Chokka, P., Bougie, J., Rampakakis, E., & Proulx, J. (2019) · CNS Spectrums · doi:10.1017/s1092852918000913 · Cited by 48 · see citing works
Vortioxetine improves symptomatic and functional outcomes in major depressive disorder: A novel dual outcome measure in depressive disorders
Christensen, M. C., Loft, H., & McIntyre, R. S. (2017) · Journal of Affective Disorders · doi:10.1016/j.jad.2017.11.081 · Cited by 46 · see citing works
A Hot-Cold Cognitive Model of Depression: Integrating the Neuropsychological Approach Into the Cognitive Theory Framework
Ahern, E., Bockting, C., & Semkovska, M. (2019) · Clinical Psychology in Europe · doi:10.32872/cpe.v1i3.34396 · Cited by 43 · see citing works
The effect of social adjustment and attachment style on suicidal behaviour
Lizardi, D., Grunebaum, M. F., Burke, A. K., Stanley, B., Mann, J. J., Harkavy‐Friedman, J., & Oquendo, M. A. (2011) · Acta Psychiatrica Scandinavica · doi:10.1111/j.1600-0447.2011.01724.x · Cited by 45 · see citing works
Subjective memory and concentration deficits in medication-free, non-elderly Asians with major depressive disorder: Prevalence and their correlates
Srisurapanont, M., Bautista, D., Chen, C., Wang, G., Udomratn, P., & Eurviriyanukul, K. (2014) · Journal of Affective Disorders · doi:10.1016/j.jad.2014.09.007 · Cited by 39 · see citing works
Differences in Perceptions of Major Depressive Disorder Symptoms and Treatment Priorities Between Patients and Health Care Providers Across the Acute, Post-Acute, and Remission Phases of Depression
Baune, B. T., & Christensen, M. C. (2019) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2019.00335 · Cited by 38 · see citing works
Relationship between prefrontal hemodynamic responses and quality of life differs between melancholia and non-melancholic depression
Tsujii, N., Mikawa, W., Tsujimoto, E., Akashi, H., Adachi, T., Kirime, E., & Shirakawa, O. (2016) · Psychiatry Research Neuroimaging · doi:10.1016/j.pscychresns.2016.04.015 · Cited by 36 · see citing works
Assessing and measuring cognitive function in major depressive disorder
Ragguett, R., Cha, D. S., Kakar, R., Rosenblat, J. D., Lee, Y. L., & McIntyre, R. S. (2016) · Evidence-Based Mental Health · doi:10.1136/eb-2016-102456 · Cited by 37 · see citing works
Assessment and Management of Cognitive and Psychosocial Dysfunctions in Patients With Major Depressive Disorder: A Clinical Review
Fiorillo, A., Carpiniello, B., Giorgi, S. D., Pia, S. L., Maina, G., Sampogna, G., Spina, E., Tortorella, A. A. V., & Vita, A. (2018) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2018.00493 · Cited by 35 · see citing works
Disability Mediates the Impact of Common Conditions on Perceived Health
Alonso, J., Vilagut, G., Adroher, N. D., Chatterji, S., He, Y., Andrade, L. H., Bromet, E., Bruffaerts, R., Fayyad, J., Florescu, S., et al. (2013) · PLoS ONE · doi:10.1371/journal.pone.0065858 · Cited by 34 · see citing works
Self-citation
Explaining heterogeneity in disability with major depressive disorder: Effects of personal and environmental characteristics
Verboom, C. E., Sentse, M., Sijtsema, J. J., Nolen, W. A., Ormel, J., & Penninx, B. W. J. H. (2011) · Journal of Affective Disorders · doi:10.1016/j.jad.2011.01.016 · Cited by 34 · see citing works
Self-citation
Phosphodiesterase: An Interface Connecting Cognitive Deficits to Neuropsychiatric and Neurodegenerative Diseases
Wang, Z., Zhang, Y., Zhang, H., & Li, Y. (2014) · Current Pharmaceutical Design · doi:10.2174/1381612820666140826115559 · Cited by 33 · see citing works
Work Functioning Measurement: Tools for Occupational Mental Health Research
Nieuwenhuijsen, K., Franche, R., & van Dijk, F. J. H. (2010) · Journal of Occupational and Environmental Medicine · doi:10.1097/jom.0b013e3181ec7cd3 · Cited by 33 · see citing works
Self Efficacy in Depression
Milanovic, M., Ayukawa, E., Usyatynsky, A., Holshausen, K., & Bowie, C. R. (2018) · The Journal of Nervous and Mental Disease · doi:10.1097/nmd.0000000000000804 · Cited by 33 · see citing works
The Association Between PTSD and Functional Outcome Is Mediated by Perception of Cognitive Problems Rather Than Objective Neuropsychological Test Performance
Samuelson, K. W., Abadjian, L. R., Jordan, J. T., Bartel, A., Vasterling, J. J., & Seal, K. H. (2017) · Journal of Traumatic Stress · doi:10.1002/jts.22223 · Cited by 31 · see citing works
The ‘cognitive footprint’ of psychiatric and neurological conditions: cross‐sectional study in the UK Biobank cohort
Cullen, B., Smıth, D. J., Deary, I. J., Evans, J. J., & Pell, J. P. (2017) · Acta Psychiatrica Scandinavica · doi:10.1111/acps.12733 · Cited by 28 · see citing works
Depressive symptoms can amplify embarrassment in essential tremor
Louis, E. D., Cosentino, S., & Huey, E. D. (2016) · Journal of Clinical Movement Disorders · doi:10.1186/s40734-016-0039-6 · Cited by 29 · see citing works
Characterizing, Assessing, and Treating Cognitive Dysfunction in Major Depressive Disorder
McIntyre, R. S., Lee, Y. L., Carmona, N. E., Subramaniapillai, M., Cha, D. S., Lee, J., Lee, J.-H., Alageel, A. A. S., Rodrigues, N. B., Park, C., et al. (2018) · Harvard Review of Psychiatry · doi:10.1097/hrp.0000000000000171 · Cited by 28 · see citing works
Executive Function and Spatial Cognition Mediate Psychosocial Dysfunction in Major Depressive Disorder
Knight, M. J., & Baune, B. T. (2018) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2018.00539 · Cited by 27 · see citing works
Eveningness is associated with greater subjective cognitive impairment in individuals with self-reported symptoms of unipolar depression
Coleman, M. Y., & Cain, S. W. (2019) · Journal of Affective Disorders · doi:10.1016/j.jad.2019.05.054 · Cited by 27 · see citing works
Subjective cognitive functioning in relation to changes in levels of depression and anxiety in youth over 3 months of treatment
Allott, K., Gao, C., Hetrick, S. E., Filia, K. M., Menssink, J. M., Fisher, C., Hickie, I. B., Herrman, H. E., Rickwood, D. J., Parker, A. G., et al. (2020) · BJPsych Open · doi:10.1192/bjo.2020.68 · Cited by 26 · see citing works
A pilot study of cognitive remediation in remitted major depressive disorder patients
Hammar, Å., Semkovska, M., Borgen, I. M. H., Myklebost, S. B., Ronold, E. H., Sveen, T., Ueland, T., Porter, R., & Johnson, S. L. (2020) · Applied Neuropsychology Adult · doi:10.1080/23279095.2020.1726919 · Cited by 27 · see citing works
The impact of cognitive challenges in major depression: the role of the primary care physician
Mattingly, G., Anderson, R. H., Mattingly, S. G., & Anderson, E. Q. (2016) · Postgraduate Medicine · doi:10.1080/00325481.2016.1221318 · Cited by 24 · see citing works
A simple attention test in the acute phase of a major depressive episode is predictive of later functional remission
Cléry-Melin, M.-L., & Gorwood, P. A. P. M. (2016) · Depression and Anxiety · doi:10.1002/da.22575 · Cited by 25 · see citing works
Cognitive performance and brain structural connectome alterations in major depressive disorder
Gruber, M., Mauritz, M., Meinert, S., Grotegerd, D., de Lange, S. C., Grumbach, P., Goltermann, J., Winter, N. R., Waltemate, L., Lemke, H., et al. (2023) · Psychological Medicine · doi:10.1017/s0033291722004007 · Cited by 24 · see citing works
Response time variability and response inhibition predict affective problems in adolescent girls, not in boys: the TRAILS study
van Deurzen, P. A. M., Buitelaar, J. K., Brunnekreef, J. A., Ormel, J., Minderaa, R. B., Hartman, C. A., Huizink, A. C., Speckens, A. E. M., Oldehinkel, A. J., & Slaats-Willemse, D. I. E. (2012) · European Child & Adolescent Psychiatry · doi:10.1007/s00787-012-0260-2 · Cited by 23 · see citing works
Self-citation
Cognitive outcomes of transcranial magnetic stimulation in treatment-resistant depression: A randomized controlled study
YILDIZ, T., OĞUZHANOĞLU, N. K., & TOPAK, O. Z. (2023) · Turkish Journal of Medical Sciences · doi:10.55730/1300-0144.5580 · Cited by 24 · see citing works
A clinical study of the efficacy of a single session of individual exercise for depressive patients, assessed by the change in saliva free cortisol level
Ida, M., Ida, I., Wada, N., Sohmiya, M., Tazawa, M., & Shirakura, K. (2013) · BioPsychoSocial Medicine · doi:10.1186/1751-0759-7-18 · Cited by 20 · see citing works
Explaining heterogeneity in disability associated with current major depressive disorder: Effects of illness characteristics and comorbid mental disorders
van der Werff, E., Verboom, C. E., Penninx, B. W. J. H., Nolen, W. A., & Ormel, J. (2010) · Journal of Affective Disorders · doi:10.1016/j.jad.2010.05.024 · Cited by 20 · see citing works
Self-citation
Determination of a clinically important difference and definition of a responder threshold for the UCSD performance-based skills assessment (UPSA) in patients with major depressive disorder
Harvey, P. D., Jacobson, W., Zhong, W., Nomikos, G. G., Christensen, M. C., Olsen, C. K., & Merikle, E. P. (2017) · Journal of Affective Disorders · doi:10.1016/j.jad.2017.02.014 · Cited by 19 · see citing works
Activation therapy for the treatment of inpatients with depression – protocol for a randomised control trial compared to treatment as usual
Averill, I. R. E., Beaglehole, B., Douglas, K. M., Jordan, J., Crowe, M., Inder, M., Lacey, C. J., FRAMPTON, C. M. A., Bowie, C. R., & Porter, R. (2019) · BMC Psychiatry · doi:10.1186/s12888-019-2038-2 · Cited by 20 · see citing works
Perceived Sleep Quality Predicts Cognitive Function in Adults with Major Depressive Disorder Independent of Depression Severity
Cha, D. S., Carmona, N. E., Cha, R. H., Zhou, A. J., Subramaniapillai, M., Mansur, R. B., Lee, Y. L., Lee, J. H., Lee, J., Almatham, F. A., et al. (2019) · Annals of Clinical Psychiatry · doi:10.1177/104012371903100112 · Cited by 17 · see citing works
An ethnographic study of the effects of cognitive symptoms in patients with major depressive disorder: the IMPACT study
Ebert, B., Miskowiak, K. W., Kloster, M., Johansen, J., Eckholm, C., Wærner, T., Holme, M., & Bruun, L. M. (2017) · BMC Psychiatry · doi:10.1186/s12888-017-1523-8 · Cited by 17 · see citing works
Depressive Symptomatology, Presenteeism Productivity, and Quality of Life
Lopes, S. L., Ferreira, A. I., Passos, A., Neves, M. V. Z. B., Sousa, C., & Sá, M. J. (2017) · Journal of Occupational and Environmental Medicine · doi:10.1097/jom.0000000000001253 · Cited by 15 · see citing works
Co-design of a Virtual Reality Cognitive Remediation Program for Depression (bWell-D) With Patient End Users and Clinicians: Qualitative Interview Study Among Patients and Clinicians
Hernandez, M. E. H., Michalak, E. E., Choudhury, N., Hewko, M. D., Torres, I. J., Menon, M., Lam, R. W. M., & Chakrabarty, T. (2023) · JMIR Serious Games · doi:10.2196/43904 · Cited by 14 · see citing works
Differences in Selective Attention and Inhibitory Control in Patients with Major Depressive Disorder and Healthy Controls Who Do Not Engage in Sufficient Physical Activity
Gerber, M., Cody, R., Beck, J., Brand, S., Donath, L., Eckert, A., Faude, O., Hatzinger, M., Imboden, C., Kreppke, J.-N., et al. (2023) · Journal of Clinical Medicine · doi:10.3390/jcm12103370 · Cited by 15 · see citing works
Network analysis of cold cognition and depression in middle-aged and elder population: the moderation of grandparenting
Yuan, D., Wu, J., Li, S., Zhang, R., Zhou, X., & Zhang, Y. (2023) · Frontiers in Public Health · doi:10.3389/fpubh.2023.1204977 · Cited by 14 · see citing works
Mediating effect of neurocognition between severity of symptoms and social-occupational function in anxious depression
Liu, W., Zhou, Y., Zheng, W., Wang, C., Zhan, Y., Li, H., Chen, L., Zhao, C., & Ning, Y. (2018) · Journal of Affective Disorders · doi:10.1016/j.jad.2018.12.129 · Cited by 16 · see citing works
Cognitive profiles in major depressive disorder: Comparing remitters and non-remitters to rTMS treatment
Aoun, M. A., Meek, B. P., & Modirrousta, M. (2019) · Psychiatry Research · doi:10.1016/j.psychres.2019.07.007 · Cited by 13 · see citing works
Beyond Empathy: Familial Incarceration, Stress Proliferation, and Depressive Symptoms Among African Americans
Smith, N. C., & Coleman, M. E. (2024) · Social Forces · doi:10.1093/sf/soad151 · Cited by 13 · see citing works
Acute Efficacy and Safety of Escitalopram Versus Desvenlafaxine and Vortioxetine in the Treatment of Depression With Cognitive Complaint: A Rater-Blinded Randomized Comparative Study
Lee, S.-H., Jeon, S. W., Shin, C., Pae, C.-U., Patkar, A. A., Masand, P. S., An, H., & Han, C. (2022) · Psychiatry Investigation · doi:10.30773/pi.2021.0368 · Cited by 12 · see citing works
Depression severity and concentration difficulties are independently associated with HRQOL in patients with unipolar depressive disorders
the ILDE Study Group, Fattori, A., Neri, L., Bellomo, A., Vaggi, M., & Mencacci, C. (2017) · Quality of Life Research · doi:10.1007/s11136-017-1595-4 · Cited by 12 · see citing works
Relationship between objective cognitive functioning and work performance among Japanese workers
Shibaoka, M., Masuda, M., Iwasawa, S., Ikezawa, S., Eguchi, H., & Nakagome, K. (2023) · Journal of Occupational Health · doi:10.1002/1348-9585.12385 · Cited by 13 · see citing works
Understanding the Impairment Associated With Depressive Symptoms
Hanson, B., & Young, M. A. (2016) · The Journal of Nervous and Mental Disease · doi:10.1097/nmd.0000000000000644 · Cited by 12 · see citing works
The mediational role of cognitive function on occupational outcomes in persons with major depressive and bipolar disorder
Tamura, J. K., Harangi, D., Rodrigues, N. B., Mansur, R. B., Subramaniapillai, M., Johnson, D. E., Rosenblat, J. D., Lee, Y. L., Vincenzo, J. D. D., Ho, R., et al. (2024) · CNS Spectrums · doi:10.1017/s1092852924002293 · Cited by 11 · see citing works
Effects of depression and excess body weight on cognition and functioning in young adults: A population-based study
Vieira, I. S., Ferrugem, S. C. R., Reyes, A. N., Branco, J. C., Mondin, T. C., Cardoso, T. D. A., Kapczinski, F. P., Souza, L. D. D. M., Jansen, K., da Silva, R. A., et al. (2020) · Journal of Affective Disorders · doi:10.1016/j.jad.2020.12.083 · Cited by 12 · see citing works
The impact of depressive symptomology, rumination and objective memory performance on subjective cognitive complaints
Szyszkowska, J., & Bala, A. (2023) · International Journal of Psychophysiology · doi:10.1016/j.ijpsycho.2023.05.351 · Cited by 11 · see citing works
Relationship between work functioning and self-reported cognitive complaints in patients with major depressive disorder treated with desvenlafaxine
Alonso‐Prieto, E., Rubino, C., Lucey, M., Evans, V. C., Tam, E. M., Woo, C., Iverson, G. L., Chakrabarty, T., Yatham, L. N., & Lam, R. W. M. (2018) · Psychiatry Research · doi:10.1016/j.psychres.2018.12.062 · Cited by 10 · see citing works
Effects of vortioxetine on functional capacity across different levels of functional impairment in patients with major depressive disorder: a University of California, San Diego Performance-based Skills Assessment (UPSA) analysis
Jacobson, W., Zhong, W., Nomikos, G. G., Christensen, M. C., Olsen, C. K., & Harvey, P. D. (2019) · Current Medical Research and Opinion · doi:10.1080/03007995.2019.1657692 · Cited by 10 · see citing works
Explaining functional outcomes in depression treatment: a multilevel modelling approach
Gadelrab, H. F., Cabello, M., Vieta, E., Valle, J., Leonardi, M., Chatterji, S., & Ayuso‐Mateos, J. L. (2010) · Disability and Rehabilitation · doi:10.3109/09638288.2010.520808 · Cited by 10 · see citing works
Testing the efficacy of INtegral Cognitive REMediation (INCREM) in major depressive disorder: study protocol for a randomized clinical trial
Vicent-Gil, M., Raventós, B., Martínez, E. D. M., González-Simarro, S., Martínez‐Arán, A., Bonnín, C. D. M., Trujols, J., Pérez‐Blanco, J., de Diego-Adeliño, J., Puigdemont, D., et al. (2019) · BMC Psychiatry · doi:10.1186/s12888-019-2117-4 · Cited by 10 · see citing works
Developing an internet-delivered intervention targeting residual cognitive symptoms after major depressive disorder: a person-based approach
Myklebost, S. B., Amundsen, O. M., Geraghty, A. W. A., İnal, Y., Hammar, Å., & Nordgreen, T. (2022) · Journal of Mental Health · doi:10.1080/09638237.2021.2022618 · Cited by 11 · see citing works
Correction: Disability Mediates the Impact of Common Conditions on Perceived Health
Alonso, J., Vilagut, G., Adroher, N. D., Chatterji, S., He, Y., Andrade, L. H., Bromet, E. J., Bruffaerts, R., Fayyad, J. A., Florescu, S., et al. (2013) · PLoS ONE · doi:10.1371/annotation/1b1c6fa4-a665-4241-8cdc-fad6eb6709fc · Cited by 10 · see citing works
Self-citation
Depressive symptoms and health-related quality of life in a heterogeneous psychiatric sample: conditional indirect effects of pain severity and interference
Teh, W. L., Liu, J., Satghare, P., Samari, E., Mok, Y. M., & Subramaniam, M. (2021) · BMC Psychiatry · doi:10.1186/s12888-021-03470-1 · Cited by 9 · see citing works
The longitudinal change pattern of cognitive subtypes in medication-free patients with major depressive disorder: a cluster analysis
Guo, W., Liu, B., Wei, X., Ju, Y., Wang, M., Dong, Q., Lu, X., Sun, J., Zhang, L., Guo, H., et al. (2023) · Psychiatry Research · doi:10.1016/j.psychres.2023.115413 · Cited by 9 · see citing works
Formulating Cognitive Functioning to Guide Personalised Treatment for People Diagnosed With Mental Disorders
Allott, K., Bryce, S., Douglas, K., Stainton, A., Wood, S., & Bowie, C. R. (2025) · Acta Psychiatrica Scandinavica · doi:10.1111/acps.13811 · Cited by 10 · see citing works
Alterations of functional connectivity in young people with depression mediate the relationship between sleep quality and cognitive function
Hu, Z., Li, W., Ye, Y., Zhang, F., Liu, H., Wang, C., Lan, X., Chen, X., You, Z., Lan, Y., et al. (2023) · Journal of Affective Disorders · doi:10.1016/j.jad.2023.08.026 · Cited by 9 · see citing works
If you feel you can’t, you won’t: the role of subjective and objective cognitive competence on psychosocial functioning in depression
Vicent-Gil, M., Trujols, J., Serra-Blasco, M., Navarra‐Ventura, G., Puigdemont, D., Alemany, C., Crivillés, S., de Diego-Adeliño, J., Cardoner, N., & Portella, M. J. (2023) · European Psychiatry · doi:10.1192/j.eurpsy.2023.2454 · Cited by 9 · see citing works
Protocol Across study: longitudinal transdiagnostic cognitive functioning, psychiatric symptoms, and biological parameters in patients with a psychiatric disorder
Nieman, D., Chavez-Baldini, U., Vulink, N., Smit, D., van Wingen, G. V., de Koning, P. D., Sutterland, A., Mocking, R. J. T., Bockting, C., Verweij, K., et al. (2020) · BMC Psychiatry · doi:10.1186/s12888-020-02624-x · Cited by 10 · see citing works
Obesity, Disability and Self-Perceived Health Outcomes in Australian Adults: A Longitudinal Analysis Using 14 Annual Waves of the HILDA Cohort
Keramat, S. A., Alam, K., Ahinkorah, B. O., Islam, M. S., Islam, M. I., Hossain, M. Z., Ahmed, S., Gow, J., & Biddle, S. (2021) · ClinicoEconomics and Outcomes Research · doi:10.2147/ceor.s318094 · Cited by 8 · see citing works
Kognitive Störungen bei Patienten mit Depression
Schilling, T. M., Bossert, M., Weisbrod, M., & Aschenbrenner, S. (2021) · Der Nervenarzt · doi:10.1007/s00115-021-01074-4 · Cited by 9 · see citing works
A Pilot Study Assessing the Effects of Goal Management Training on Cognitive Functions among Individuals with Major Depressive Disorder and the Effect of Post-Traumatic Symptoms on Response to Intervention
Boyd, J. E., Sanger, B., Cameron, D. H., Protopopescu, A., McCabe, R. E., O’Connor, C., Lanius, R. A., & McKinnon, M. C. (2022) · Brain Sciences · doi:10.3390/brainsci12070864 · Cited by 8 · see citing works
The influence of age on ECT efficacy in depression, mania, psychotic depression and schizophrenia: A transdiagnostic analysis.
Mahmood, S., Tan, X.-C., Chen, B.-R., & Tor, P. (2024) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2024.07.012 · Cited by 7 · see citing works
An updated systematic review and appraisal of the pathophysiologic mechanisms of probiotics in alleviating depression
Sulaiman, N. N. Y., Nizam, N. B. M., Noor, N. A. M., Lim, S. M., Ramasamy, K., Alabsi, A. M., & Fareez, I. M. (2025) · Nutritional Neuroscience · doi:10.1080/1028415x.2025.2531357 · Cited by 6 · see citing works
Objective speech measures capture depressive symptoms and associated cognitive difficulties
Wiseman, M., Yep, R., Alexander, M. W., Pople, C. B., Perri, L., Gopinath, G., Vasileiadi, M., Robin, J., Spilka, M. J., Simpson, W. S., et al. (2025) · Translational Psychiatry · doi:10.1038/s41398-025-03728-2 · Cited by 6 · see citing works
Computational biological analysis reveals that HIF-1 and FoxO signaling pathways influence cognitive impairment in patients with depression
Zhuo, C., Zhang, Y., Zhang, Q., Yang, L., Xi-ming, C., Ma, X., Li, R., Wang, L., Tian, H., & Mao, F. (2025) · Translational Psychiatry · doi:10.1038/s41398-025-03775-9 · Cited by 6 · see citing works

The mediational role of cognition on functional outcomes in major depressive disorder
McIntyre, R. S., Cha, D. S., & Soczynska, J. K. (2014) · Oxford University Press eBooks · doi:10.1093/med/9780199688807.003.0006
Neurocognition and Depressive Symptoms have Unique Pathways to Predicting Different Domains of Functioning in Major Depressive Disorder
Wood‐Ross, C., Tran, T. B., Milanovic, M., Jokic, R., Milev, R. V., & Bowie, C. R. (2022) · The Canadian Journal of Psychiatry · doi:10.1177/07067437221133375 · Cited by 3 · see citing works
Depression, Disability and Intermediate Pathways: A Review of Longitudinal Studies in Elders
Schillerstrom, J. E., Royall, D. R., & Palmer, R. F. (2008) · Journal of Geriatric Psychiatry and Neurology · doi:10.1177/0891988708320971 · Cited by 128 · see citing works
COGNITIVE DEFICITS AND FUNCTIONAL OUTCOMES IN MAJOR DEPRESSIVE DISORDER: DETERMINANTS, SUBSTRATES, AND TREATMENT INTERVENTIONS: Review: Cognitive Deficits and Functional Outcomes in MDD
McIntyre, R. S., Cha, D. S., Soczynska, J. K., Woldeyohannes, H. O., Gallaugher, L. A., Kudlow, P., Alsuwaidan, M., & Baskaran, A. (2013) · Depression and Anxiety · doi:10.1002/da.22063 · Cited by 765 · see citing works
Psychotic symptoms and neurocognition among patients with major depressive disorder: A chained mediation model of depressive symptoms and socio-occupational functioning
Zeng, Y., Zhang, F., Liu, H., Li, W., Ning, Y., & Zhou, Y. (2023) · Journal of Affective Disorders · doi:10.1016/j.jad.2023.04.005 · Cited by 3 · see citing works

Authors: Buist‐Bouwman, M. A., Ormel, J., De Graaf, R., De Jonge, P., Van Sonderen, E., Alonso, J., Bruffaerts, R., Vollebergh, W. A. M., & the ESEMeD/MHEDEA 2000 investigators
Affiliations: University Medical Center Groningen (NL)
Universitair Ziekenhuis Leuven (BE)
Utrecht University (NL)
ORCID: Ormel, J.
Alonso, J.
Bruffaerts, R.
Vollebergh, W. A. M.
Venue: Acta Psychiatrica Scandinavica
Publisher: Wiley
Published: 2008-11-11
Volume: 118
Issue: 6
Pages: 451-458
ISSN: 0001-690X (ISSN-L)
1600-0447
DOI: 10.1111/j.1600-0447.2008.01285.x
PMC: PMC3659780
OpenAlex: W2170135777
Cited by: 127
References: 41
Citations by year: 2026: 2 · 2025: 4 · 2024: 6 · 2023: 11 · 2022: 7 · 2021: 5 · 2020: 6 · 2019: 16 · 2018: 17 · 2017: 10 · 2016: 13 · 2015: 10 · 2014: 8 · 2013: 3 · 2012: 1
FWCI: 3.56
Type: journal article
Language: en
Open access: bronze
doi.org
Licence: onlinelibrary.wiley.com/termsAndConditions#vor (vor)
Locations: Acta Psychiatrica Scandinavica (publishedVersion)
Research portal (Tilburg University) (publishedVersion)
PubMed (publishedVersion)
Europe PMC (PubMed Central) (acceptedVersion)
PubMed Central (acceptedVersion)
RECERCAT (Consorci de Serveis Universitaris de Catalunya) (acceptedVersion)
Data Archiving and Networked Services (DANS) (submittedVersion)
Leicester Research Archive (University of Leicester) (submittedVersion)
University of Groningen research database (University of Groningen / Centre for Information Technology) (submittedVersion)
Repositori digital de la UPF (Universitat Pompeu Fabra) (submittedVersion)
Funders: John D. and Catherine T. MacArthur Foundation (R01 DA016558, R13-MH066849)
Bristol-Myers Squibb
Eli Lilly and Company
Pfizer
GlaxoSmithKline
World Health Organization
European Commission (1999-01042, QLG5–1999-01042, SANCO2004123, 2004123)
Generalitat de Catalunya (01042)
Regione Piemonte
National Institutes of Health (5r13mh066849-04, 5r01mh069864-04, 5r01mh070884-05)
Pfizer Foundation (R01‐MH069864, R01-DA016558, R13-MH066849)
Pan American Health Organization
Instituto de Salud Carlos III
Departament de Salut, Generalitat de Catalunya
National Institute of Mental Health (R13-MH-066849, R01‐MH070884, MH069864, MH066849, R01‐MH069864)
National Institute on Drug Abuse (K05DA015799, R01DA016558)
Fogarty International Center (FIRCA R01-TW006481, R01-TW006481, R03TW006481)
Topics: Social Sciences › Psychology › Social Psychology › Mental Health Treatment and Access
Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Aging, Health, and Disability
Keywords: depression, role functioning, mediation, activity limitation, embarrassment, disability, International Classification of Functioning, Disability and Health, major depressive episode, cognitive impairment
MeSH terms: Activities of Daily Living, Adaptation, Psychological, Adolescent, Adult, Aged, Cognition Disorders, Cross-Sectional Studies, Major Depressive Disorder, Disability Evaluation, Efficiency, Europe, Health Surveys, Humans, Middle Aged, Models, Psychological, Motivation, Personality Assessment, Role, Shame, Social Environment, Cost of Illness, Young Adult

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Mediators of the association between depression and role functioning

Abstract

Integrity signals

Claims the paper makes

Claims other papers make about this one

Self-check

Cites

Cited by

Related

Record

About these checks