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Metabolic switching and fuel choice during T‐cell differentiation and memory development
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Summary: Clearance or control of pathogens or tumors usually requires T‐cell‐mediated immunity. As such, understanding the mechanisms that govern the function, maintenance, and persistence of T cells will likely lead to new treatments for controlling disease. During an immune response, T‐cell development is marked by striking changes in metabolism. There is a growing appreciation that these metabolic changes underlie the capacity of T cells to perform particular functions, and this has led to a recent focus on the idea that the manipulation of cellular metabolism can be used to shape adaptive immune responses. Although interest in this area has grown in the last few years, a full understanding of the metabolic control of T‐cell functions, particularly during an immune response in vivo , is still lacking. In this review, we first provide a basic overview of metabolism in T cells, and then we focus on recent studies providing new or updated insights into the regulation of metabolic pathways and how they underpin T‐cell differentiation and memory T‐cell development.
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“signalling pathways involving the T cell receptor (TCR), CD28 and the PI3K–Akt–mTOR axis upregulate the expression of glucose transporter 1 (GLUT1), increasing the rate of aerobic glycolysis71,72”
From The role of mitochondria in rheumatic diseases (2022) · cites this paper as [71]
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Cites
Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation
Vander Heiden, M. G., Cantley, L. C., & Thompson, C. B. (2009) · Science · doi:10.1126/science.1160809 · Cited by 16,197
The Biology of Cancer: Metabolic Reprogramming Fuels Cell Growth and Proliferation
DeBerardinis, R. J., Lum, J. J., Hatzivassiliou, G., & Thompson, C. B. (2008) · Cell Metabolism · doi:10.1016/j.cmet.2007.10.002 · Cited by 4,088
mTOR: from growth signal integration to cancer, diabetes and ageing
Zoncu, R., Efeyan, A., & Sabatini, D. M. (2011) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm3025 · Cited by 3,941
Rapamycin fed late in life extends lifespan in genetically heterogeneous mice
Harrison, D. E., Strong, R., Sharp, Z. D., Nelson, J. F., Astle, C. M., Flurkey, K., Nadon, N. L., Wilkinson, J. E., Frenkel, K., Carter, C. S., et al. (2009) · Nature · doi:10.1038/nature08221 · Cited by 3,766
On Respiratory Impairment in Cancer Cells
Warburg, O. H. (1956) · Science · doi:10.1126/science.124.3215.269 · Cited by 3,472
A C. elegans mutant that lives twice as long as wild type
Kenyon, C., Chang, J., Gensch, E., Rudner, A., & Tabtiang, R. (1993) · Nature · doi:10.1038/366461a0 · Cited by 3,387
Kim, D., Sarbassov, D. D., Ali, S. M., King, J. E., Latek, R. R., Erdjument‐Bromage, H., Tempst, P., & Sabatini, D. M. (2002) · Cell · doi:10.1016/s0092-8674(02)00808-5 · Cited by 3,051
DeBerardinis, R. J., Mancuso, A., Daikhin, E., Nissim, I., Yudkoff, M., Wehrli, S., & Thompson, C. B. (2007) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0709747104 · Cited by 2,622
AMP-activated protein kinase (AMPK) action in skeletal muscle via direct phosphorylation of PGC-1α
Jäger, S., Handschin, C., St.-Pierre, J., & Spiegelman, B. M. (2007) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0705070104 · Cited by 2,491
Ido expression by dendritic cells: tolerance and tryptophan catabolism
Mellor, A. L., & Munn, D. H. (2004) · Nature Reviews Immunology · doi:10.1038/nri1457 · Cited by 2,341
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Fox, A., & Blazeck, J. (2024) · Metabolic Engineering · doi:10.1016/j.ymben.2024.10.009 · Cited by 7
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Perucha, B., Martinez-Tabar, M., Sánchez-Moreno, I., Justicia-Lirio, P., Lozano, T., & Lasarte, J. J. (2025) · Pharmacological Research · doi:10.1016/j.phrs.2025.107928 · Cited by 7
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Willett, B. A. S., Thompson, S. B., Chen, V., Darehshouri, A., Jackson, C. L., Brunetti, T. M., D’Alessandro, A., Klarquist, J. S., Nemkov, T. G., & Kedl, R. M. (2025) · Cell Reports · doi:10.1016/j.celrep.2025.115610 · Cited by 9
Orlik, C., Berschneider, K. M., Jahraus, B., Niesler, B., Balta, E., Schäkel, K., Schröder–Braunstein, J., Souto‐Carneiro, M., & Samstag, Y. (2022) · Frontiers in Immunology · doi:10.3389/fimmu.2022.1016112 · Cited by 6
Zhang, W., Cai, H., & Tan, W. (2018) · Journal of Biotechnology · doi:10.1016/j.jbiotec.2018.09.010 · Cited by 6
Zhang, Q., Liu, B., Zhao, L., Lian, Y., Yuan, X., Zhang, Y. L., Lin, J., & Li, C. (2018) · Artificial Organs · doi:10.1111/aor.13367 · Cited by 6
T cell metabolism in graft-versus-host disease
Zou, Y., & Chen, B. J. (2020) · Blood Science · doi:10.1097/bs9.0000000000000035 · Cited by 6
Chen, S., Nguyen, T. D., Lee, K.-Z., & Liu, D. (2024) · Biotechnology Advances · doi:10.1016/j.biotechadv.2024.108434 · Cited by 7
The Vast Universe of T Cell Diversity: Subsets of Memory Cells and Their Differentiation
Jandus, C., Martínez-Usatorre, A., Viganó, S., Zhang, L., & Romero, P. J. (2016) · Methods in molecular biology · doi:10.1007/978-1-4939-6548-9_1 · Cited by 8
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Kagoya, Y. (2022) · International Immunology · doi:10.1093/intimm/dxac016 · Cited by 5
Saleki, K., & Rezaei, N. (2022) · Springer eBooks · doi:10.1007/978-3-030-80962-1_9-1 · Cited by 5
Huckestein, B. R., Antos, D., Manni, M. L., Zeng, K., Miller, L. M., Parenteau, K. L., Gelhaus, S. L., Mullett, S. J., Shoemaker, J. E., & Alcorn, J. F. (2024) · American Journal of Physiology-Lung Cellular and Molecular Physiology · doi:10.1152/ajplung.00407.2023 · Cited by 4
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Qu, D., Zhao, L., Zhang, Q., Li, R., Li, Y., & Wang, H. (2025) · Biochemical Pharmacology · doi:10.1016/j.bcp.2025.117217 · Cited by 4
Gurevich‐Shapiro, A., Zwicky, P., Winter, E. E., Zada, M., Shapira, N., Barboy, O., Chalan, P., Sharet-Eshed, R., Kedmi, M., Ingelfinger, F., et al. (2025) · Cancer Research · doi:10.1158/0008-5472.can-25-3596 · Cited by 4
Liu, X., Hu, W., Sun, J., & Wu, B. (2025) · Nature Communications · doi:10.1038/s41467-025-66064-5 · Cited by 5
Gmyrek, G. B., Predki, P., Gershburg, E., & Carr, D. J. J. (2022) · Journal of Virology · doi:10.1128/jvi.01724-21 · Cited by 4
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Culberson, A. L., Bowles, A. C., Wang, B., Kottke, P. A., Jimenez, A. C., Roy, K., & Fedorov, A. G. (2023) · Cytotherapy · doi:10.1016/j.jcyt.2023.03.010 · Cited by 4
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Zhang, X., Gao, Y., Tang, K., Li, Z., Halberstam, A. A., Zhou, L., & Perry, R. J. (2024) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00346.2023 · Cited by 4
Krug, A., Mhaidly, R., Tosolini, M., Mondragón, L., Tari, G., Martinez-Turtos, A., Paul, R., Asnafi, V., Marchetti, S., Mascio, L. D., et al. (2024) · Cell Death Discovery · doi:10.1038/s41420-024-02061-9 · Cited by 4
Zhao, Y., Zhu, W., Dong, S., Zhang, H., & Zhou, W. (2025) · Journal of Gastroenterology and Hepatology · doi:10.1111/jgh.16873 · Cited by 5
Metabolic landscape and rewiring in normal hematopoiesis, leukemia and aging
Fang, H., Yu, E., Liu, C., Eapen, C., Cheng, C., & Hu, T. (2025) · Seminars in Cancer Biology · doi:10.1016/j.semcancer.2025.02.003 · Cited by 5
Metabolic regulation of γδ intraepithelial lymphocytes
Alonso, S., & Edelblum, K. L. (2023) · Discovery Immunology · doi:10.1093/discim/kyad011 · Cited by 4
Expression of bovine interleukin 15 and evaluation of its biological activity in vitro
Nagaraj, V. K., Lijo, J., Dechamma, H. J., Bhanuprakash, V., Suresh, B., Ganesh, K., & Reddy, G. R. (2015) · Veterinary World · doi:10.14202/vetworld.2015.295-300 · Cited by 4
Mitochondria and Antiviral Immunity
Thomas, S., & Gale, M. (2016) · Springer eBooks · doi:10.1007/978-1-4939-3612-0_10 · Cited by 4
Mathiassen, T. B. W., Hansen, M. R., Karlsson, M. G., Hadrup, S. R., Ormhøj, M., & Jensen, P. R. (2025) · Scientific Reports · doi:10.1038/s41598-025-24712-2 · Cited by 3
Taraballi, F., & Corradetti, B. (2026) · Journal of Materials Chemistry B · doi:10.1039/d6tb00355a · Cited by 3
Fu, W., Xie, Q., Yu, P., Liu, S., Xu, L., Ye, X., Zhao, W., Wang, Q., Pan, Y., Zhang, Z., et al. (2025) · Frontiers in Immunology · doi:10.3389/fimmu.2025.1530214 · Cited by 4
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Goodin, D. A., & Frieboes, H. B. (2022) · Journal of Theoretical Biology · doi:10.1016/j.jtbi.2022.111383 · Cited by 3
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Effector Tc17 cells resist shift from OXPHOS to aerobic glycolysis
John, R., Mudalagiriyappa, S., Chandrashekar, N., & Nanjappa, S. G. (2025) · Frontiers in Immunology · doi:10.3389/fimmu.2025.1571221 · Cited by 3
Zubatkina, O. V., Dobrodeeva, L. K., Popov, A. A., Васильевна, С. А., & Kruglov, S. D. (2020) · Экология человека · doi:10.33396/1728-0869-2020-8-20-25 · Cited by 3
Scrima, R. (2014) · Journal of Clinical & Cellular Immunology · doi:10.4172/2155-9899.1000184 · Cited by 2
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Sawinski, D. L., & Maltzman, J. S. (2015) · American Journal of Transplantation · doi:10.1111/ajt.13348 · Cited by 3
Rodia, C. N., Li, D., Tambini, N. S., Johnson, Z. K., Jellison, E. R., Vella, A. T., & Kohan, A. B. (2019) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/823690 · Cited by 3
Ma, L., Morgan, D. M., Sulkaj, I., Yousefpour, P., Whittaker, C. A., Abraham, W. D., Li, N., Love, J. C., & Irvine, D. J. (2022) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2022.10.05.511036 · Cited by 3
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Scaglione, M., Knight, M., Trihemasava, K., Rome, K., Archambault, A., Oh, J., Tanaka, E., Hall, E., Le, T. N. V., Lines, C. L., et al. (2025) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2025.01.22.632829 · Cited by 3
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Huang, M., Pan, J., Sei, S., Wang, Y., & You, M. (2024) · Advanced Therapeutics · doi:10.1002/adtp.202400430 · Cited by 2
Leung, P. Y. M., Graver, A. S., Katerelos, M., Skene, A., Whitlam, J. B., Power, D. A., & Mount, P. F. (2025) · BMC Nephrology · doi:10.1186/s12882-025-04196-y · Cited by 2
Huang, Y., Chen, Z., Yang, X., & Ren, B. (2025) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2025.1550958 · Cited by 2
Mercier‐Letondal, P., Marton, C., Royer, B., Peixoto, P., Dehecq, B., Adotévi, O., Galaine, J., & Godet, Y. (2025) · Molecular Therapy — Methods & Clinical Development · doi:10.1016/j.omtm.2025.101553 · Cited by 3
Sun, Y., Tang, Y., Ortiz, P., Rausseo, B. N., Pazdrak, B., Elzohary, L., Katailiha, A. S., Talukder, A. H., Yee, C., Davis, R. E., et al. (2025) · Frontiers in Immunology · doi:10.3389/fimmu.2025.1572342 · Cited by 2
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Abd-El-Raouf, R., Harrison-Gleason, J., Kim, J., Wai, C. M., Yerlioglu, K. L., Ananías-Sáez, C., Ksiazek, A., Poomkudy, J. T., Araínga, M., Bose, D., et al. (2026) · JCI Insight · doi:10.1172/jci.insight.198810 · Cited by 2
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Lei, Y., Yu, J., Huo, X., Li, Z., Wang, J., Jiang, Y., Yu, Y., Huang, Y., Jiang, W., Tian, J., et al. (2025) · Journal of Neuroinflammation · doi:10.1186/s12974-025-03538-9 · Cited by 2
DJ-1 depletion prevents immunoaging in T-cell compartments
Zeng, N., Capelle, C., Baron, A. G., Kobayashi, T., Ciré, S., Tslaf, V., Leonard, C. A., Coowar, D., Koseki, H., Westendorf, A. M., et al. (2022) · immuneACCESS · doi:10.21417/nz2022embor · Cited by 2
He, H., Yao, Y., Tang, L., Li, Y., Li, Z., Liu, B., & Lan, Y. (2023) · Frontiers in Immunology · doi:10.3389/fimmu.2023.1240859 · Cited by 1
Mahendran, R., Venn, Z. L., Alomar, F. A., Abbas-Abad, A. N., Edagwa, B., Gorantla, S., & Bidasee, K. R. (2025) · Viruses · doi:10.3390/v17040547 · Cited by 1
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Saleki, K., & Rezaei, N. (2025) · Springer eBooks · doi:10.1007/978-3-032-00749-0_9 · Cited by 1
Kates, M., Paul, M. S., Ohashi, P. S., & Saibil, S. D. (2025) · STAR Protocols · doi:10.1016/j.xpro.2025.104173 · Cited by 1
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Anderson, L., Mason, N. J., & O’Connor, R. S. (2026) · Advances in pharmacology · doi:10.1016/bs.apha.2026.05.001 · Cited by 1
Papaneophytou, C. P., & Petrou, C. C. (2026) · Frontiers in Bioscience-Landmark · doi:10.31083/fbl49369 · Cited by 1
Chen, N., Yue, Y., & Zhou, L. (2026) · Frontiers in Immunology · doi:10.3389/fimmu.2026.1879634 · Cited by 2
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Bustos, X. E., Tordesillas, L., Martinez-Planes, E., Fontela, M. G., Snedal, S. A., Rossetti, R., Izumi, V., Fang, B., Koomen, J. M., Welsh, E. A., et al. (2026) · Cellular & Molecular Immunology · doi:10.1038/s41423-026-01475-y
Dynamic Metabolism in Immune Response.
Al-Hommrani, M., Chakraborty, P., Chatterjee, S., & Mehrotra, S. (2016) · PubMed · Cited by 1
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Purev, E., & Fry, T. J. (2017) · Annals of Lymphoma · doi:10.21037/aol.2017.10.02 · Cited by 2
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Ferreira, C. M., Barbosa, A. M., Pereira, I. M., & Torrado, E. (2018) · Experientia supplementum · doi:10.1007/978-3-319-74932-7_8 · Cited by 1
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Land, W. G. (2018) · Springer eBooks · doi:10.1007/978-3-319-78655-1_35 · Cited by 1
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Holzinger, A., & Abken, H. (2020) · Learning materials in biosciences · doi:10.1007/978-3-030-54630-4_10 · Cited by 2
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Kotha, A., Madu, C. O., & Lu, Y. (2023) · IntechOpen eBooks · doi:10.5772/intechopen.108830 · Cited by 1
Congrave‐Wilson, Z., Kim, M., Sutherland, A., Jumarang, J., Lee, Y., Valle, J. D., Cheng, W. A., Antunes, R. D. S., & Pannaraj, P. S. (2023) · Journal of Immunological Methods · doi:10.1016/j.jim.2023.113520 · Cited by 1
Adaptive immunity and metabolism
Verbist, K., Sharma, P., Beere, H. M., & Green, D. R. (2025) · Elsevier eBooks · doi:10.1016/b978-0-443-15447-8.00008-8 · Cited by 1
Voda, A.-I., Correa, K., Hamp, J., Moscrop, C., Dustin, M. L., & Jostins-Dean, L. (2022) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2022.11.23.517727 · Cited by 1
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MIALLOT, R., Millet, V., Roger, A., Fenouil, R., Tardivel, C., Martin, J., Shintu, L., BERCHARD, P., Lanza, J. S., MALISSEN, B., et al. (2022) · Research Square · doi:10.21203/rs.3.rs-2345803/v1 · Cited by 1
Fert, A., Richard, J., Marchand, L. R., Planas, D., Routy, J., Chomont, N., Finzi, A., & Ancuța, P. (2024) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2024.02.15.580166 · Cited by 1
Obenaus, M., Poupault, C. L., McGinnis, C. S., Prange, C. J., Jiang, H., Su, L., Chen, X. T., Miao, Z., Muldoon, J. J., Yao, W., et al. (2025) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.64898/2025.12.04.692214 · Cited by 1
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Klenerman, P., & Fergusson, J. R. (2015) · Elsevier eBooks · doi:10.1016/b978-0-12-394447-4.30087-6
Piccoli, C., Quarato, G., Ripoli, M. C., Mastrolonardo, M., & Capitanio, N. (2014)
Previte, D. M. (2017) · D-Scholarship@Pitt (University of Pittsburgh)
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Gao, F. (2017) · TSpace (University of Toronto)
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Byersdorfer, C. A., & Reddy, P. R. (2019) · Elsevier eBooks · doi:10.1016/b978-0-12-812630-1.00019-0
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Rosa, M. H. (2020) · Digital Library of Theses and Dissertations (Universidade de São Paulo) · doi:10.11606/d.17.2020.tde-18082020-213816
AN, J. W. (2020) · ERA: Education and Research Archive (University of Alberta) · doi:10.7939/r3-c3fw-vz10
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Chan, Y. T. (2019) · TSpace (University of Toronto)
Alley, J. (2021) · Iowa State University Digital Repository (Iowa State University) · doi:10.31274/etd-20210609-3
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Barlier, C., Barriales, D., Samosyuk, A., Jung, S., Ravichandran, S., Medvedeva, Y. A., Anguíta, J., & del Sol, A. (2021) · Cell Death and Disease · doi:10.1038/s41419-021-04075-y
Metabolic Profile of Adaptive Immune Cells
Domínguez-Amorocho, O. A., Soto‐Heredero, G., & Mittelbrunn, M. (2021) · Springer eBooks · doi:10.1007/978-3-030-86684-6_6
Metabolic Pathways in Immune Cells Commitment and Fate
Alves, R. W., da Silva, E. M., Doretto-Silva, L., & Andrade‐Oliveira, V. (2021) · Springer eBooks · doi:10.1007/978-3-030-86684-6_4
Validity of maternal-reported weight and height of 2-5 year old children (Scientific Letter)
Jani, R., Mihrshahi, S., Mandalika, S., & Mallan, K. M. (2014) · QUT ePrints (Queensland University of Technology)
DECOMPOSITION OF LINE-BROADENING CALCULATIONS INTO STATE-TO-STATE TERMS*
Flannery, C., Steinfeld, J. I., & Gamache, R. R. (1992) · The Knowledge Bank (The Ohio State University)
Gurshaney, S., Alvarez, A. M., Ezhakunnel, K., Manalo, A., Huynh, T.-H., Le, N.-T., Lupu, D. S., Gardell, S. J., & Nguyen, H. D. (2021) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2021.12.06.471421
Косякова, Н. И., Акуленко, М. В., Сероштанова, И. Э., Ильеня, Э. Л., Balyasnikova, V. S., Панкратова, Е. В., & Андреева, Л. А. (2021) · doi:10.17513/np.461
McDermott, M., & Rahmati, M. (2021) · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature · doi:10.3410/f.738095897.793584287
Metadata
- Authors
- van der Windt, G. J. W., & Pearce, E. L.
- Affiliations
- Department of Pathology & Immunology Washington University School of Medicine St. Louis MO USA
- Washington University in St. Louis (US)
- Corresponding author
- Pearce, Erika L.
- ORCID
- Pearce, Erika L.
- Venue
- Immunological Reviews
- Publisher
- Wiley
- Published
- 2012-08-14
- Volume
- 249
- Issue
- 1
- Pages
- 27-42
- ISSN
- 0105-2896 (ISSN-L)
- 1600-065X
- PMC
- PMC3645891
- OpenAlex
- W1999195849
- Cited by
- 563
- References
- 157
- Citations by year
- 2026: 38 · 2025: 52 · 2024: 44 · 2023: 55 · 2022: 58 · 2021: 53 · 2020: 54 · 2019: 44 · 2018: 41 · 2017: 35 · 2016: 22 · 2015: 26 · 2014: 23 · 2013: 14 · 2012: 3
- FWCI
- 1.95
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Immunological Reviews (publishedVersion)
- PubMed (publishedVersion)
- Pure Amsterdam UMC (publishedVersion)
- Europe PMC (PubMed Central) (acceptedVersion)
- PubMed Central (acceptedVersion)
- Data Archiving and Networked Services (DANS) (submittedVersion)
- MPG.PuRe (Max Planck Society) (submittedVersion, other-oa)
- Funders
- Emerald Foundation
- Nederlandse Organisatie voor Wetenschappelijk Onderzoek
- National Institutes of Health
- National Cancer Institute (R21CA158823)
- National Institute of Allergy and Infectious Diseases (R01AI091965)
- Topics
- Life Sciences › Immunology and Microbiology › Immunology › T-cell and B-cell Immunology
- Life Sciences › Immunology and Microbiology › Immunology › Immune cells in cancer
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Cancer Research › Cancer, Hypoxia, and Metabolism
- Keywords
- T cell metabolism, metabolic switch, fuel selection, T cell differentiation, memory T cells, metabolic reprogramming, adaptive immune response, T cell immunity
- MeSH terms
- Animals, Cell Differentiation, Energy Metabolism, Humans, Immunity, Cellular, Immunologic Memory, Lymphocyte Activation, Mitochondria, T-Lymphocytes, Cell Proliferation
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Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
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