Cited by 43Antifungal resistance and susceptibilityFungal Plant Pathogen ControlYeasts and Rust Fungi Studies

EUCAST Technical Note on Candida and micafungin, anidulafungin and fluconazole

Cavling Arendrup, Maiken, Cuenca‐Estrella, Manuel, Lass‐Flörl, Cornelia, Hope, William W., The European Committee on Antimicrobial Susceptibility Testing – Subcommittee on Antifungal Susceptibility Testing (EUCAST‐AFST)·2014·Mycoses

Abstract

The European Committee on Antimicrobial Susceptibility Testing Subcommittee on Antifungal Susceptibility Testing has determined breakpoints for micafungin and revised breakpoints for anidulafungin and fluconazole for Candida spp. This Technical Note is based on the corresponding rationale documents (http://www.eucast.org). The micafungin breakpoints are based on PK data, animal PK/PD data, microbiological data and clinical experience. The anidulafungin breakpoints for C. parapsilosis and fluconazole breakpoints for C. glabrata have been modified to species-specific values that categorise the wild-type as intermediate to accommodate use of these compounds in some clinical situations.

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Crossref · 10.1111/myc.12170

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Authors
Cavling Arendrup, M., Cuenca‐Estrella, M., Lass‐Flörl, C., Hope, W. W., & The European Committee on Antimicrobial Susceptibility Testing – Subcommittee on Antifungal Susceptibility Testing (EUCAST‐AFST)
Affiliations
  • Unit of Mycology Department of Microbiology & Infection Control Statens Serum Institute Copenhagen Denmark
  • Mycology National Center for Microbiology Madrid Spain
  • Innsbruck Medical University (AT)
  • University of Liverpool (GB)
Venue
Mycoses
Publisher
Wiley
Published
2014-01-13
Volume
57
Issue
6
Pages
377-379
ISSN
  • 0027-5557 (ISSN-L)
  • 0933-7407
  • 1439-0507
OpenAlex
W1971164793
Cited by
43
References
20
Citations by year
2026: 2 · 2023: 2 · 2022: 2 · 2021: 1 · 2020: 3 · 2019: 2 · 2018: 2 · 2017: 10 · 2016: 6 · 2015: 5 · 2014: 6 · 2013: 2
FWCI
6.30
Type
journal article
Language
en
Open access
closed
Locations
  • Mycoses (publishedVersion)
  • PubMed (publishedVersion)
Funders
  • National Institute for Health and Care Research (CS/08/08/10)
  • National Institutes of Health
Topics
  • Health Sciences › Medicine › Infectious Diseases › Antifungal resistance and susceptibility
  • Life Sciences › Agricultural and Biological Sciences › Ecology, Evolution, Behavior and Systematics › Fungal Plant Pathogen Control
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Yeasts and Rust Fungi Studies
Keywords
Candida, micafungin, anidulafungin, fluconazole, antifungal susceptibility breakpoints, Candida parapsilosis, Candida glabrata, intermediate susceptibility, antifungal agents
MeSH terms
Micafungin, Anidulafungin, Animals, Antifungal Agents, Candida, Europe, Humans, Microbial Sensitivity Tests, Fluconazole, Echinocandins, Lipopeptides

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