The role of incretins in glucose homeostasis and diabetes treatment

Kim, Wook, Egan, Josephine M.·2008·Pharmacological Reviews

Cites (564)

Items 201–400 of 564

  1. Differential Processing of Proglucagon by the Subtilisin-like Prohormone Convertases PC2 and PC3 to Generate either Glucagon or Glucagon-like Peptide
    Yves Rouillé, Sean Martin, Donald F. Steiner · 1995 · Journal of Biological Chemistry
  2. Phosphorylation of RIM1α by PKA Triggers Presynaptic Long-Term Potentiation at Cerebellar Parallel Fiber Synapses
    György Lónárt, Susanne Schoch, Pascal S. Kaeser, C.Jenny Larkin, Thomas Christian Südhof, David J. Linden · 2003 · Cell
  3. Interoceptive stress activates glucagon-like peptide-1 neurons that project to the hypothalamus
    Linda Rinaman · 1999 · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology
  4. Glucose-dependent Insulinotropic Polypeptide (GIP) Stimulation of Pancreatic β-Cell Survival Is Dependent upon Phosphatidylinositol 3-Kinase (PI3K)/Protein Kinase B (PKB) Signaling, Inactivation of the Forkhead Transcription Factor Foxo1, and Down-regulation of bax Expression
    Sujin Kim, Kyle D. Winter, Cuilan Nian, Makoto Tsuneoka, Yoshiro Koda, Christopher H.S. McIntosh · 2005 · Journal of Biological Chemistry
  5. β-Arrestin-1 mediates glucagon-like peptide-1 signaling to insulin secretion in cultured pancreatic β cells
    Sonoda, Noriyuki, Imamura, Takeshi, Yoshizaki, Takeshi, Babendure, Jennie L., Lu, Juu-Chin, Olefsky, Jerrold M. · 2008 · Proceedings of the National Academy of Sciences
  6. Glucose-Dependent Insulinotropic Polypeptide Is a Growth Factor for β (INS-1) Cells by Pleiotropic Signaling
    Andrea Trümper, K Trümper, Heidi Trusheim, R. Arnold, Burkhard Göke, Dieter Hörsch · 2001 · Molecular Endocrinology
  7. Functional GIP Receptors Are Present on Adipocytes
    Yip, Rupert G.-C., Boylan, Michael O., Kieffer, Timothy J., Wolfe, M. Michael · 1998 · Endocrinology
  8. GIP receptor antagonism reverses obesity, insulin resistance, and associated metabolic disturbances induced in mice by prolonged consumption of high-fat diet
    Paula L. McClean, Nigel Irwin, Roslyn S. Cassidy, Jens Juul Holst, Victor A. Gault, Peter R. Flatt · 2007 · American Journal of Physiology-Endocrinology and Metabolism
  9. Glucagonostatic and Insulinotropic Action of Glucagonlike Peptide I-(7–36)-Amide
    Ryoya Komatsu, Tatsuo Matsuyama, Mitsuyoshi Namba, Nobuaki Watanabe, Hidehiko Itoh, Norio Kôno, Seiichiro Tarui · 1989 · Diabetes
  10. Reduced Insulinotropic Effect of Gastric Inhibitory Polypeptide in First-Degree Relatives of Patients With Type 2 Diabetes
    Juris Jendrik Meier, Katrin Hücking, Jens Juul Holst, Carolyn Fiona Deacon, Wolff Schmiegel, Michael Albrecht Nauck · 2001 · Diabetes
  11. β-Adrenergic regulation requires direct anchoring of PKA to cardiac Ca V 1.2 channels via a leucine zipper interaction with A kinase-anchoring protein 15
    Joanne T. Hulme, Teddy W.‐C. Lin, Ruth E. Westenbroek, Todd Scheuer, William A. Catterall · 2003 · Proceedings of the National Academy of Sciences
  12. Effects of hypoglycemic agents on vascular complications in patients with adult-onset diabetes. IV. A preliminary report on phenoformin results
    Genell L. Knatterud · 1971 · JAMA
  13. Functional expression of the rat glucagon-like peptide-I receptor, evidence for coupling to both adenylyl cyclase and phospholipase-C.
    Wheeler, M B, Lu, M, Dillon, J S, Leng, X H, Chen, C, Boyd, A E · 1993 · Endocrinology
  14. Characterisation of the processing by human neutral endopeptidase 24.11 of GLP-1(7–36) amide and comparison of the substrate specificity of the enzyme for other glucagon-like peptides
    Hupe-Sodmann, Karin, McGregor, Gerard Patrick, Bridenbaugh, Robert, Göke, Rüdiger, Göke, Burkhard, Thole, Hubert, Zimmermann, Bodo, Voigt, Karlheinz · 1995 · Regulatory Peptides
  15. Glucagon-Like Peptide 1 Induces Differentiation of Islet Duodenal Homeobox-1–Positive Pancreatic Ductal Cells Into Insulin-Secreting Cells
    Hongxiang Hui, Chris V. E. Wright, Riccardo Perfetti · 2001 · Diabetes
  16. Rapid ATP‐Dependent Priming of Secretory Granules Precedes Ca <sup>2+</sup> ‐Induced Exocytosis in Mouse Pancreatic B‐Cells
    Eliasson, Lena, Renström, Erik, Ding, Wei‐Guang, Proks, Peter, Rorsman, Patrik · 1997 · The Journal of Physiology
  17. Sulfonylurea Receptor Type 1 Knock-out Mice Have Intact Feeding-stimulated Insulin Secretion despite Marked Impairment in Their Response to Glucose
    Chiyo Shiota, Olof Larsson, Kathy D. Shelton, Masakazu Shiota, Alexander M. Efanov, Marianne Høy, Jill Lindner, Suwattanee Kooptiwut, Lisa Juntti‐Berggren, Jesper Gromada et al. · 2002 · Journal of Biological Chemistry
  18. Proglucagon is processed to glucagon by prohormone convertase PC2 in alpha TC1-6 cells.
    Yves Rouillé, Gunilla Torstensdotter Westermark, S K Martin, Donald F. Steiner · 1994 · Proceedings of the National Academy of Sciences
  19. Incretin-Based Therapies in Type 2 Diabetes Mellitus
    Chee W. Chia, Josephine Mary Egan · 2008 · The Journal of Clinical Endocrinology & Metabolism
  20. Effects of hypoglycemic agents on vascular complications in patients with adult-onset diabetes. 3. Clinical implications of UGDP results
    Goldner Mg · 1971 · JAMA
  21. Glucagon-Like Peptide 1 Secretion by the L-Cell
    Gareth E. Lim, Patricia Lee Brubaker · 2006 · Diabetes
  22. Glucagon-like peptide-1 mobilizes intracellular Ca2+ and stimulates mitochondrial ATP synthesis in pancreatic MIN6 beta-cells
    Takashi Tsuboi, Gabriela da Silva Xavier, George G. Holz, Laurence Sophie Jouaville, Andrew P. Thomas, Guy A. Rutter · 2003 · Biochemical Journal
  23. Activation of Lipoprotein Lipase by Glucose-dependent Insulinotropic Polypeptide in Adipocytes
    Kim, Su-Jin, Nian, Cuilan, McIntosh, Christopher H.S. · 2007 · Journal of Biological Chemistry
  24. Pancreatic Glucagon-Like Peptide-1 Receptor Couples to Multiple G Proteins and Activates Mitogen-Activated Protein Kinase Pathways in Chinese Hamster Ovary Cells
    Chahrzad Montrose‐Rafizadeh, Pavel V. Avdonin, Michael J. Garant, Buel D. Rodgers, Sutapa Kole, Huan Min Yang, Michael A. Levine, William F. Schwindinger, Michel Bernier · 1999 · Endocrinology
  25. Gastric inhibitory polypeptide (GIP) and insulin in obesity: Increased response to stimulation and defective feedback control of serum levels
    W. Creutzfeldt, Reinhold Ebert, B. Willms, H. Frerichs, John Canvin Brown · 1978 · Diabetologia
  26. CD38 Disruption Impairs Glucose-induced Increases in Cyclic ADP-ribose, [Ca2+] , and Insulin Secretion
    Ichiro Kato, Yasuhiko Yamamoto, Miki Fujimura, Naoya Noguchi, Shin Takasawa, Hiroshi Okamoto · 1999 · Journal of Biological Chemistry
  27. Electronimmunocytochemical evidence for the K cell localization of gastric inhibitory polypeptide (GIP) im man
    Alison M. J. Buchan, Julia Margaret Polak, C. Capella, Enrico Solcia, A. G. E. Pearse · 1978 · Histochemistry and Cell Biology
  28. GUT-HORMONE PROFILE IN CŒLIAC DISEASE
    Harvey S. Besterman, Stephen Robert Bloom, D. L. Sarson · 1978 · The Lancet
  29. GLP‐1 receptor agonists are growth and differentiation factors for pancreatic islet beta cells
    Josephine Mary Egan, Angela Bulotta, Hongxiang Hui, Riccardo Perfetti · 2003 · Diabetes/Metabolism Research and Reviews
  30. Defective Glucose-Dependent Insulinotropic Polypeptide Receptor Expression in Diabetic Fatty Zucker Rats
    Lynn, Francis C., Pamir, Nathalie, Ng, Eddy H.C., McIntosh, Christopher H.S., Kieffer, Timothy J., Pederson, Raymond A. · 2001 · Diabetes
  31. Changes in arterial blood pressure and heart rate induced by glucagon-like peptide-1-(7-36) amide in rats.
    J. Barragán, Raquel E. Rodríguez, E. Blázquez · 1994 · American Journal of Physiology
  32. Exendin-4 Uses Irs2 Signaling to Mediate Pancreatic β Cell Growth and Function
    Sunmin Park, Xiaocheng Charlie Dong, Tracy L. Fisher, Sarah Dunn, Abdulkadir Omer, Gordon C. Weir, Morris F. White · 2005 · Journal of Biological Chemistry
  33. Effects of glucose-dependent insulinotropic peptide on osteoclast function
    Qing Zhong, Takashi Itokawa, Supriya Sridhar, Kehong Ding, Ding Xie, Baolin Kang, Wendy Bollinger Bollag, Roni J. Bollag, Mark W. Hamrick, Karl Leonard Insogna et al. · 2006 · American Journal of Physiology-Endocrinology and Metabolism
  34. cAMP‐regulated guanine nucleotide exchange factor II (Epac2) mediates Ca2+‐induced Ca2+ release in INS‐1 pancreatic β‐cells
    Guoxin Kang, Oleg G. Chepurny, George G. Holz · 2001 · The Journal of Physiology
  35. Vagal hepatopancreatic reflex effect evoked by intraportal appearance of tGLP-1
    Hajime Nakabayashi, MITSUAKI NISHIZAWA, A. Nakagawa, R Takeda, Akira Niijima · 1996 · American Journal of Physiology-Endocrinology and Metabolism
  36. Portal GLP-1 administration in rats augments the insulin response to glucose via neuronal mechanisms
    Börk Balkan, Xue Li · 2000 · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology
  37. Suppression of glucose production by GLP-1 independent of islet hormones: A novel extrapancreatic effect
    Prigeon, Ronald L., Quddusi, Shaista, Paty, Breay, D'Alessio, David A. · 2003 · American Journal of Physiology-Endocrinology and Metabolism
  38. Gastric Inhibitory Polypeptide as an Endogenous Factor Promoting New Bone Formation after Food Ingestion
    Tsukiyama, Katsushi, Yamada, Yuichiro, Yamada, Chizumi, Harada, Norio, Kawasaki, Yukiko, Ogura, Masahito, Bessho, Kazuhisa, Li, Minqi, Amizuka, Norio, Sato, Masahiro et al. · 2006 · Molecular Endocrinology
  39. Piccolo, a Ca2+ Sensor in Pancreatic β-Cells
    Kei Fujimoto, Tadao Shibasaki, Norihide Yokoi, Yasushige Kashima, Masanari Matsumoto, Takashi Sasaki, Naoko Tajima, Toshihiko Iwanaga, Susumu Seino · 2002 · Journal of Biological Chemistry
  40. Dexamethasone Induces Cell Death in Insulin-Secreting Cells, an Effect Reversed by Exendin-4
    Felicia Ranta, Diana Avram, Susanne Berchtold, Martina Düfer, Gisela Drews, Florian J.W. Lang, Susanne Ullrich · 2006 · Diabetes
  41. Mechanisms of mitogenic and anti-apoptotic signaling by glucose-dependent insulinotropic polypeptide in beta(INS-1)-cells
    Andrea Trümper, K Trümper, Dieter Hörsch · 2002 · Journal of Endocrinology
  42. Anchoring of protein kinase A facilitates hormone-mediated insulin secretion
    Linda B. Lester, Lorene K. Langeberg, John D. Scott · 1997 · Proceedings of the National Academy of Sciences
  43. Cardiac Function in Mice Lacking the Glucagon-Like Peptide-1 Receptor
    Robert Gros, Xiaomang You, Laurie L. Baggio, M. Golam Kabir, Al Muktafi Sadi, Imran N. Mungrue, Thomas G. Parker, Qingling Huang, Daniel J. Drucker, Mansoor Husain · 2003 · Endocrinology
  44. Gastric Inhibitory Polypeptide (GIP) Stimulated by Fat Ingestion in Man
    James M. Falko, Samuel E. Crockett, Samuel Cataland, Ernest L. Mazzaferri · 1975 · The Journal of Clinical Endocrinology & Metabolism
  45. Glucose-Dependent Insulinotropic Polypeptide Is Expressed in Adult Hippocampus and Induces Progenitor Cell Proliferation
    Nyberg, Jenny, Anderson, Michelle F., Meister, Björn, Alborn, Ann-Marie, Ström, Anna-Karin, Brederlau, Anke, Illerskog, Ann-Christin, Nilsson, Ola, Kieffer, Timothy J., Hietala, Max Albert et al. · 2005 · The Journal of Neuroscience
  46. Glucagon-like peptide-1 is a physiological incretin in rat.
    Z Wang, R M Wang, A. A. Owji, David M. Smith, Mohammad A. Ghatei, Stephen Robert Bloom · 1995 · Journal of Clinical Investigation
  47. Inhibition of Kv2.1 Voltage-dependent K+Channels in Pancreatic β-Cells Enhances Glucose-dependent Insulin Secretion
    Patrick E. MacDonald, Sabine Sewing, Jianli Wang, Jamie W. Joseph, Simon R. Smukler, George Sakellaropoulos, Jing Wang, Monique C. Saleh, Catherine B. Chan, Robert G. Tsushima et al. · 2002 · Journal of Biological Chemistry
  48. Glucagon-Like Peptide-1 Inhibits Pancreatic ATP-Sensitive Potassium Channels via a Protein Kinase A- and ADP-Dependent Mechanism
    Peter E. Light, Jocelyn E. Manning Fox, Michael J Riedel, Michael B. Wheeler · 2002 · Molecular Endocrinology
  49. Activation of a cAMP-regulated Ca2+-Signaling Pathway in Pancreatic β-Cells by the Insulinotropic Hormone Glucagon-like Peptide-1
    Holz, George G., Leech, Colin A., Habener, Joel F. · 1995 · Journal of Biological Chemistry
  50. Reduction of the Incretin Effect in Rats by the Glucagon-Like Peptide 1 Receptor Antagonist Exendin (9–39) Amide
    Frank Thomas Kolligs, Hans-C. Fehmann, Rüdiger Göke, Burkhard Göke · 1995 · Diabetes
  51. Insulinotropic Glucagon-Like Peptide I Receptor Expression in Glucagon-Producing α-Cells of the Rat Endocrine Pancreas
    Heller, R Scott, Kieffer, Timothy J, Habener, Joel F · 1997 · Diabetes
  52. Transcription factor FoxO1 mediates glucagon-like peptide-1 effects on pancreatic β-cell mass
    Buteau, Jean, Spatz, Marianne L., Accili, Domenico · 2006 · Diabetes
  53. Cloning and functional expression of the human glucagon-like peptide-1 (GLP-1) receptor
    Joseph Stephen Dillon, Y Tanizawa, M B Wheeler, X H Leng, B B Ligon, D U Rabin, H Yoo-Warren, M A Permutt, A E Boyd · 1993 · Endocrinology
  54. Glucagon-like peptide-1 receptor (GLP1-R) mRNA in the rat hypothalamus.
    Paul J. Shughrue, Malcolm V. Lane, Istvan J. Merchenthaler · 1996 · Endocrinology
  55. Neutral endopeptidase 24.11 and dipeptidyl peptidase IV are both mediators of the degradation of glucagon-like peptide 1 in the anaesthetised pig
    Astrid Plamboeck, Jens Juul Holst, Richard David Carr, Carolyn Fiona Deacon · 2005 · Diabetologia
  56. Glucose-dependent insulinotropic polypeptide receptor knockout mice have altered bone turnover
    Ding Xie, Hua Cheng, Mark W. Hamrick, Qing Zhong, Ke-Hong Ding, Daniel José Correa, Sandra Williams, Anthony L. Mulloy, Wendy Bollinger Bollag, Roni J. Bollag et al. · 2005 · Bone
  57. Chemical Ablation of Gastric Inhibitory Polypeptide Receptor Action by Daily (Pro3)GIP Administration Improves Glucose Tolerance and Ameliorates Insulin Resistance and Abnormalities of Islet Structure in Obesity-Related Diabetes
    Victor A. Gault, Nigel Irwin, Brian D. Green, Jane T. McCluskey, Brett Greer, Clifford J. Bailey, Patrick Harriott, Finbarr P.M. O'Harte, Peter R. Flatt · 2005 · Diabetes
  58. Polypyrimidine tract-binding protein promotes insulin secretory granule biogenesis
    Klaus-Peter Knoch, Hendrik Bergert, Barbara Borgonovo, Hans‐Detlev Saeger, Anke Altkrüger, Paul Verkade, Michele Solimena · 2004 · Nature Cell Biology
  59. Interplay of Nutrients and Hormones in the Regulation of Glucagon Release*
    PIPELEERS, D. G., SCHUIT, F. C., SCHRAVENDIJK, C. F. H. VAN, WINKEL, M. VAN DE · 1985 · Endocrinology
  60. Regulation of Glucagon-Like Peptide-1 Synthesis and Secretion in the GLUTag Enteroendocrine Cell Line1
    PATRICIA L. BRUBAKER, Jürgen Schloos, Daniel J. Drucker · 1998 · Endocrinology
  61. Enhanced glucose-dependent insulinotropic polypeptide secretion and insulinotropic action in glucagon-like peptide 1 receptor -/- mice.
    Raymond A. Pederson, Malathy Satkunarajah, Christopher H.S. McIntosh, Louise A. Scrocchi, Daisy Flamez, Frans C Schuit, Daniel J. Drucker, Michael B. Wheeler · 1998 · Diabetes
  62. Glucagon gene regulatory region directs oncoprotein expression to neurons and pancreatic a cells
    Shimon Efrat, Gladys Teitelman, Muhammad Anwar, David A. Ruggiero, Douglas Hanahan · 1988 · Neuron
  63. Inhibition of Histamine-, Pentagastrin-, and Insulin-Stimulated Canine Gastric Secretion by Pure “Gastric Inhibitory Polypeptide”
    Raymond A. Pederson, John C. Brown · 1972 · Gastroenterology
  64. Dihydrotestosterone Decreases Tumor Necrosis Factor-α and Lipopolysaccharide-Induced Inflammatory Response in Human Endothelial Cells
    Giuseppe Danilo Norata, Gianpaolo Tibolla, P.M. Seccomandi, Angelo Poletti, Alberico Luigi Catapano · 2006 · The Journal of Clinical Endocrinology & Metabolism
  65. Control of Insulin mRNA Stability in Rat Pancreatic Islets
    Linda Tillmar, Carina Carlsson, Nils Welsh · 2002 · Journal of Biological Chemistry
  66. Regulation of Intestinal Proglucagon- Derived Peptide Secretion by Intestinal Regulatory Peptides*
    Patricia Lee Brubaker · 1991 · Endocrinology
  67. Glucose-Dependent Insulinotropic Polypeptide Promotes β-(INS-1) Cell Survival via Cyclic Adenosine Monophosphate-Mediated Caspase-3 Inhibition and Regulation of p38 Mitogen-Activated Protein Kinase
    Jan A. Ehses, Vanbric R. Casilla, Timothy Doty, John Andrew Pospisilik, Kyle D. Winter, Hans‐Ulrich Demuth, Raymond A. Pederson, Christopher H.S. McIntosh · 2003 · Endocrinology
  68. Pharmacokinetic actions of exendin‐4 in the rat: Comparison with glucagon‐like peptide‐1
    David G. Parkes, Carolyn M. Jodka, Pam Smith, Sonali Nayak, Liz Rinehart, Ron Gingerich, Kim S. Chen, Andrew John Young · 2001 · Drug Development Research
  69. Muscarinic Receptors Control Postprandial Release of Glucagon-Like Peptide-1: In Vivo and in Vitro Studies in Rats
    Younès Anini, Tanya Hansotia, Patricia Lee Brubaker · 2002 · Endocrinology
  70. Glucagon-Like Peptide-1 Gene Therapy in Obese Diabetic Mice Results in Long-Term Cure of Diabetes by Improving Insulin Sensitivity and Reducing Hepatic Gluconeogenesis
    Lee, Young-Sun, Shin, Seungjin, Shigihara, Toshikatsu, Hahm, Eunsil, Liu, Meng-Ju, Han, Jaeseok, Yoon, Ji-Won, Jun, Hee-Sook · 2007 · Diabetes
  71. Gastric inhibitory polypeptide does not inhibit gastric emptying in humans
    Juris Jendrik Meier, Oliver Goetze, Jens Anstipp, Dirk Hagemann, Jens Juul Holst, Wolfgang Ekkehard Schmidt, Baptist Gallwitz, Michael Albrecht Nauck · 2004 · American Journal of Physiology-Endocrinology and Metabolism
  72. Interaction of Gastric Inhibitory Polypeptide, Glucose, and Arginine on Insulin and Glucagon Secretion from the Perfused Rat Pancreas*
    PEDERSON, RAYMOND A., BROWN, JOHN C. · 1978 · Endocrinology
  73. Glucagon-Like Peptide-1
    Maı̀re E. Doyle · 2001 · Recent Progress in Hormone Research
  74. Secretion of Proglucagon-Derived Peptides in Response to Intestinal Luminal Nutrients*
    J. N. ROBERGE, Patricia Lee Brubaker · 1991 · Endocrinology
  75. Gut incretin hormones in identical twins discordant for non-insulin-dependent diabetes mellitus (NIDDM)—evidence for decreased glucagon-like peptide 1 secretion during oral glucose ingestion in NIDDM twins
    Allan Arthur Vaag, Jens Juul Holst, Aage Vølund, Henning Beck‐Nielsen · 1996 · European Journal of Endocrinology
  76. Cross Talk between the Insulin and Wnt Signaling Pathways: Evidence from Intestinal Endocrine L Cells
    Fenghua Yi, Jane Sun, Gareth E. Lim, Ivan George Fantus, Patricia Lee Brubaker, Tianru Jin · 2008 · Endocrinology
  77. The inhibitory effect of glucagon-like peptide-1 (GLP-1) 7-36 amide on gastric acid secretion in humans depends on an intact vagal innervation.
    Wettergren, A, Wøjdemann, M, Meisner, S, Stadil, F, Holst, J J · 1997 · Gut
  78. GLP-1 reduces intestinal lymph flow, triglyceride absorption, and apolipoprotein production in rats
    Xiaofa Qin, Hui Shen, Min Liu, Qing Yang, Shuqin Zheng, Mary Sabo, David A. D’Alessio, Patrick Tso · 2005 · American Journal of Physiology-Gastrointestinal and Liver Physiology
  79. Exendin-4 Protects β-Cells From Interleukin-1β–Induced Apoptosis by Interfering With the c-Jun NH2-Terminal Kinase Pathway
    M. Ferdaoussi, S. Abdelli, Jiang-Yan Yang, M. Cornu, G. Niederhauser, D. Favre, C. Widmann, R. Regazzi, B. Thorens, G. Waeber et al. · 2008 · Diabetes
  80. Glucagon-Like Peptide I Reduces Postprandial Glycemic Excursions in IDDM
    John Dupre, Margaret T. Behme, IRENE M. HRAMIAK, Philip A. McFarlane, Michael P. Williamson, Pamela L. Zabel, Thomas J. McDonald · 1995 · Diabetes
  81. Alpha-Cell-Specific Expression of the Glucagon Gene Is Conferred to the Glucagon Promoter Element by the Interactions of DNA-Binding Proteins
    Jacques Philippé, Daniel J. Drucker, Willhart Knepel, Lisa I. Jepeal, Ziva Misulovin, Joel Francis Habener · 1988 · Molecular and Cellular Biology
  82. Effects of liraglutide (NN2211), a long‐acting GLP‐1 analogue, on glycaemic control and bodyweight in subjects with Type 2 diabetes
    Mark N. Feinglos, Mohammed F. Saad, F X Pi-Sunyer, Bob An, Olga M. Santiago, on behalf of the Liraglutide Dose‐Response Study Group · 2005 · Diabetic Medicine
  83. Forty years of calcitonin—where are we now? A tribute to the work of Iain Macintyre, FRS
    Zaidi, M, Inzerillo, A.M, Moonga, B.S, Bevis, P.J.R, Huang, C.L.-H · 2002 · Bone
  84. cAMP sensor Epac as a determinant of ATP‐sensitive potassium channel activity in human pancreatic β cells and rat INS‐1 cells
    Guoxin Kang, Oleg G. Chepurny, Brian Malester, Michael J. Rindler, Holger Rehmann, Johannes L. Bos, Frank Schwede, William A. Coetzee, George G. Holz · 2006 · The Journal of Physiology
  85. Postprandial stimulation of insulin release by glucose-dependent insulinotropic polypeptide (GIP). Effect of a specific glucose-dependent insulinotropic polypeptide receptor antagonist in the rat.
    Chi‐Chuan Tseng, Timothy J. Kieffer, Linda A. Jarboe, Ted Björn Usdin, M. Michael Wolfe · 1996 · Journal of Clinical Investigation
  86. Pax 4 and 6 regulate gastrointestinal endocrine cell development
    Lars‐Inge Larsson, Luc St‐Onge, DAVID MICHAEL HOUGAARD · 1998 · Mechanisms of Development
  87. Somatostatin restrains the secretion of glucagon-like peptide-1 and -2 from isolated perfused porcine ileum
    Lene Hansen, Bolette Hartmann, Thue Bisgaard, Hitoshi Mineo, Peer Nobert Jørgensen, Jens Juul Holst · 2000 · American Journal of Physiology-Endocrinology and Metabolism
  88. Stimulation of pancreatic β-cell replication by incretins involves transcriptional induction of cyclin D1 via multiple signalling pathways
    Birgitte Nissen Friedrichsen, Nicole Neubauer, Ying C. Lee, Vivian K Gram, Niels Blume, Jacob Steen Petersen, Jens Høiriis Nielsen, Annette Møldrup · 2006 · Journal of Endocrinology
  89. Glucagon gene 5'-flanking sequences direct expression of simian virus 40 large T antigen to the intestine, producing carcinoma of the large bowel in transgenic mice.
    Y C Lee, S.L. Asa, Daniel J. Drucker · 1992 · Journal of Biological Chemistry
  90. GLP-1 stimulates secretion of macromolecules from airways and relaxes pulmonary artery
    G. Richter, O.C. Feddersen, Ulrich Wagner, Peter Josef Barth, Rüdiger Göke, Burkhard Göke · 1993 · American Journal of Physiology-Lung Cellular and Molecular Physiology
  91. Five Weeks of Treatment with the GLP-1 Analogue Liraglutide Improves Glycaemic Control and Lowers Body weight in Subjects with Type 2 Diabetes
    Michael Albrecht Nauck, Marcus Hompesch, R. Filipczak, T. Le, Marija D. Zdravkovic, Jakub Janusz Gumprecht · 2006 · Experimental and Clinical Endocrinology & Diabetes
  92. Insulin regulation of the glucagon gene is mediated by an insulin-responsive DNA element.
    J Philippe · 1991 · Proceedings of the National Academy of Sciences
  93. Glucose-dependent insulinotropic peptide-overexpressing transgenic mice have increased bone mass
    Xie, Ding, Zhong, Qing, Ding, Ke-Hong, Cheng, Hua, Williams, Sandra, Correa, Daniel, Bollag, Wendy B., Bollag, Roni J., Insogna, Karl, Troiano, Nancy et al. · 2007 · Bone
  94. Glucagon-Like Peptide-1 Causes Pancreatic Duodenal Homeobox-1 Protein Translocation from the Cytoplasm to the Nucleus of Pancreatic β-Cells by a Cyclic Adenosine Monophosphate/Protein Kinase A-Dependent Mechanism
    Xiaolin Wang, Jie Zhou, Maı̀re E. Doyle, Josephine Mary Egan · 2001 · Endocrinology
  95. Neural contribution to the effect of glucagon-like peptide-1-(7—36) amide on arterial blood pressure in rats
    Barragán, José Manuel, Eng, John, Rodríguez, Raquel, Blázquez, Enrique · 1999 · American Journal of Physiology-Endocrinology and Metabolism
  96. Glucose-dependent insulinotropic peptide is an integrative hormone with osteotropic effects
    Roni J. Bollag, Qing Zhong, Ke Ding, P Phillips, L Zhong, F Qin, J Cranford, Anthony L. Mulloy, Richard S. Cameron, Carlos M. Isales · 2001 · Molecular and Cellular Endocrinology
  97. Proprotein convertases (PC1/PC3 and PC2) in normal and neoplastic human tissues: their use as markers of neuroendocrine differentiation
    Lucio Scopsi, M Gullo, Franco O. Rilke, S Martin, Donald F. Steiner · 1995 · The Journal of Clinical Endocrinology & Metabolism
  98. Agonist-induced internalization and recycling of the glucagon-like peptide-1 receptor in transfected fibroblasts and in insulinomas
    Christian Widmann, Wanda Dolci, Bernard Thorens · 1995 · Biochemical Journal
  99. Peptides and the control of meal size
    Stephen C. Woods, David B. West, Leslie J. Stein, L. David McKay, Elizabeth C. Lotter, Stephanie G. Porte, Nancy J. Kenney, Daniel Porte · 1981 · Diabetologia
  100. Glucagon-Like Peptide-1 Regulates the Beta Cell Transcription Factor, PDX-1, in Insulinoma Cells
    Xiaolin Wang, Catherine M. Cahill, Marco A. Piñeyro, Jie Zhou, Maı̀re E. Doyle, Josephine Mary Egan · 1999 · Endocrinology
  101. Glucose-Dependent Insulinotropic Polypeptide-Mediated Up-Regulation of β-Cell Antiapoptotic Bcl-2 Gene Expression Is Coordinated by Cyclic AMP (cAMP) Response Element Binding Protein (CREB) and cAMP-Responsive CREB Coactivator 2
    Su‐jin Kim, Cuilan Nian, Scott B. Widenmaier, Christopher H.S. McIntosh · 2007 · Molecular and Cellular Biology
  102. Caveolin-1 Regulates Cellular Trafficking and Function of the Glucagon-Like Peptide 1 Receptor
    Colin A. Syme, Lei Zhang, Alessandro Bisello · 2006 · Molecular Endocrinology
  103. Glucose-Dependent Insulinotropic Polypeptide Enhances Adipocyte Development and Glucose Uptake in Part Through Akt Activation
    Song, Diane H., Getty–Kaushik, Lisa, Tseng, Eva, Simon, Jonathan, Corkey, Barbara E., Wolfe, M. Michael · 2007 · Gastroenterology
  104. Glucagon-Like Peptide-1 Limits Myocardial Stunning following Brief Coronary Occlusion and Reperfusion in Conscious Canines
    Nikolaidis, Lazaros A., Doverspike, Aaron, Hentosz, Teresa, Zourelias, Lee, Shen, You-Tang, Elahi, Dariush, Shannon, Richard P. · 2005 · The Journal of Pharmacology and Experimental Therapeutics
  105. An Albumin-Exendin-4 Conjugate Engages Central and Peripheral Circuits Regulating Murine Energy and Glucose Homeostasis
    Baggio, Laurie L., Huang, Qingling, Cao, Xiemin, Drucker, Daniel J. · 2008 · Gastroenterology
  106. GLP-1 action in L6 myotubes is via a receptor different from the pancreatic GLP-1 receptor
    Huan Min Yang, Josephine Mary Egan, Y. Wang, Chris D. Moyes, Jesse Roth, Marshall H. Montrose, Chahrzad Montrose‐Rafizadeh · 1998 · American Journal of Physiology-Cell Physiology
  107. Muscarinic Receptors Control Glucagon-Like Peptide 1 Secretion by Human Endocrine L Cells
    Younès Anini, Patricia Lee Brubaker · 2003 · Endocrinology
  108. Effects of the novel (Pro3)GIP antagonist and exendin(9–39)amide on GIP- and GLP-1-induced cyclic AMP generation, insulin secretion and postprandial insulin release in obese diabetic (ob/ob) mice: evidence that GIP is the major physiological incretin
    Victor A. Gault, Finbarr P.M. O'Harte, Patrick Harriott, MH Mooney, BD Green, Peter R. Flatt · 2003 · Diabetologia
  109. Essential Requirement for Pax6 in Control of Enteroendocrine Proglucagon Gene Transcription
    Mary Elizabeth Hill, Sylvia L. Asa, Daniel J. Drucker · 1999 · Molecular Endocrinology
  110. Exendin-4, but not glucagon-like peptide-1, is cleared exclusively by glomerular filtration in anaesthetised pigs
    Simonsen, L., Holst, J. J., Deacon, C. F. · 2006 · Diabetologia
  111. Glucose-dependent Insulinotropic Polypeptide Activates the Raf-Mek1/2-ERK1/2 Module via a Cyclic AMP/cAMP-dependent Protein Kinase/Rap1-mediated Pathway
    Jan A. Ehses, Steven Pelech, Raymond A. Pederson, Christopher H.S. McIntosh · 2002 · Journal of Biological Chemistry
  112. Glucagon-like peptide-1 stimulates luteinizing hormone-releasing hormone secretion in a rodent hypothalamic neuronal cell line.
    Beak, S A, Heath, M M, Small, C J, Morgan, D G, Ghatei, M A, Taylor, A D, Buckingham, J C, Bloom, S R, Smith, D M · 1998 · Journal of Clinical Investigation
  113. Neuroendocrine Function and Response to Stress in Mice with Complete Disruption of Glucagon-Like Peptide-1 Receptor Signaling1
    MacLusky, Neil J., Cook, Sonya, Scrocchi, Louise, Shin, Jennifer, Kim, Julie, Vaccarino, Franco, Asa, Sylvia L., Drucker, Daniel J. · 2000 · Endocrinology
  114. Glucagon-Like Peptide-1 7-36 Amide and Peptide YY from the L-Cell of the Ileal Mucosa Are Potent Inhibitors of Vagally Induced Gastric Acid Secretion in Man
    Wettergren, A., Petersen, H., ørskov, C., Christiansen, J., Sheikh, S. P., Holst, J. J. · 1994 · Scandinavian Journal of Gastroenterology
  115. Pancreatic tumoral cell line AR42J: an amphicrine model
    Jean Christophe · 1994 · American Journal of Physiology-Gastrointestinal and Liver Physiology
  116. Leptin interacts with glucagon‐like peptide‐1 neurons to reduce food intake and body weight in rodents
    Anthony Peter Goldstone, Julian G. Mercer, Irene Gunn, Kim M. Moar, C. M. B. Edwards, Michela Rossi, Jane K. Howard, Shahnawaz Rasheed, Mandy D. Turton, Caroline J. Small et al. · 1997 · FEBS Letters
  117. Glucagon-like peptide-1 (GLP-1) and glucose metabolism in human myocytes
    M.A. Luque, Nieves González, L Marquez, Alicia Acitores, Araceli Redondo, Mónica Morales, Isabel Valverde, ML Villanueva-Penacarrillo · 2002 · Journal of Endocrinology
  118. Reversal of islet GIP receptor down-regulation and resistance to GIP by reducing hyperglycemia in the Zucker rat
    Piteau, Shalea, Olver, Amy, Kim, Su-Jin, Winter, Kyle, Pospisilik, John Andrew, Lynn, Francis, Manhart, Susanne, Demuth, Hans-Ulrich, Speck, Madeleine, Pederson, Raymond A. et al. · 2007 · Biochemical and Biophysical Research Communications
  119. Rapid Oscillations in Plasma Glucagon-Like Peptide-1 (GLP-1) in Humans: Cholinergic Control of GLP-1 Secretion via Muscarinic Receptors1
    H.J. Balks, Jens Juul Holst, A. von zur Mühlen, Georg E. Brabant · 1997 · The Journal of Clinical Endocrinology & Metabolism
  120. Hypersecretion of Gastric Inhibitory Polypeptide Following Oral Glucose in Diabetes Mellitus
    S A Ross, John C. Brown, John Dupré · 1977 · Diabetes
  121. Functional expression of the rat pancreatic islet glucose-dependent insulinotropic polypeptide receptor: ligand binding and intracellular signaling properties.
    Wheeler, M B, Gelling, R W, McIntosh, C H, Georgiou, J, Brown, J C, Pederson, R A · 1995 · Endocrinology
  122. Glucagon-like peptide 1 stimulates insulin gene promoter activity by protein kinase A-independent activation of the rat insulin I gene cAMP response element.
    Gunnar Skoglund, Mehboob Ali Hussain, George G. Holz · 2000 · Diabetes
  123. The role of phospholipid-derived mediators including arachidonic acid, its metabolites, and inositoltrisphosphate and of intracellular Ca2+ in glucose-induced insulin secretion by pancreatic islets.
    J. Turk, B. Wolf, M. L. Mcdaniel · 1987 · Progress in lipid research
  124. Intravenous infusion of glucagon-like peptide-1 potently inhibits food intake, sham feeding, and gastric emptying in rats
    Prasanth K. Chelikani, Alvin C. Haver, Roger D. Reidelberger · 2005 · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology
  125. Glucose-dependent insulinotropic polypeptide receptor null mice exhibit compensatory changes in the enteroinsular axis
    Pamir, Nathalie, Lynn, Francis C., Buchan, Alison M. J., Ehses, Jan, Hinke, Simon A., Pospisilik, J. Andrew, Miyawaki, Kazumasa, Yamada, Yuichiro, Seino, Yutaka, McIntosh, Christopher H. S. et al. · 2003 · American Journal of Physiology-Endocrinology and Metabolism
  126. Identical mRNA for preproglucagon in pancreas and gut
    Ulrike Novak, Andrew F. Wilks, Gary N. Buell, Stephen J. McEwen · 1987 · European Journal of Biochemistry
  127. Reversal of impaired GIP and insulin secretion in patients with pancreatogenic steatorrhea following enzyme substitution
    Reinhold Ebert, W. Creutzfeldt · 1980 · Diabetologia
  128. Pancreatic-duodenal homeobox 1 -role in gastric endocrine patterning
    Lars‐Inge Larsson, Ole D. Madsen, Palle Serup, Jörgen Jönsson, Helena Edlund · 1996 · Mechanisms of Development
  129. Prohormone Convertase 1/3 Is Essential for Processing of the Glucose-dependent Insulinotropic Polypeptide Precursor
    Randi Ugleholdt, Marie-Louise H. Poulsen, Peter Johannes Holst, Jean-Claude Irminger, Cathrine Ørskov, Jens Pedersen, METTE MARIE ROSENKILDE, Xiaorong Zhu, Donald F. Steiner, Jens Juul Holst · 2006 · Journal of Biological Chemistry
  130. Generation of Nicotinic Acid Adenine Dinucleotide Phosphate and Cyclic ADP-Ribose by Glucagon-Like Peptide-1 Evokes Ca2+ Signal That Is Essential for Insulin Secretion in Mouse Pancreatic Islets
    Byung-Ju Kim, Kwang-Hyun Park, Chang-Yeol Yim, Shin Takasawa, Hiroshi Okamoto, Mie-Jae Im, Uh‐Hyun Kim · 2008 · Diabetes
  131. Myocardial Ischaemia-reperfusion Injury is Attenuated by Intact Glucagon Like Peptide-1 (GLP-1) in the In Vitro Rat Heart and may Involve the p70s6K Pathway
    Amal Bose, Mihaela M. Mocanu, Richard David Carr, Derek M. Yellon · 2007 · Cardiovascular Drugs and Therapy
  132. Role of Central Nervous System Glucagon-Like Peptide-1 Receptors in Enteric Glucose Sensing
    Claude Knauf, Patrice D. Cani, Donghoon Kim, Miguel A. Iglesias, Chantal Chabo, Aurélie Waget, André Colom, Sophie Rastrelli, Nathalie M. Delzenne, Daniel J. Drucker et al. · 2008 · Diabetes
  133. Initial experience with GLP-1 treatment on metabolic control and myocardial function in patients with type 2 diabetes mellitus and heart failure
    Inga Sigurros Thrainsdottir, Klas Malmberg, Arne Olsson, M. Gutniak, Lars Rydén · 2004 · Diabetes and Vascular Disease Research
  134. Glucagon-like peptide-1(7-36) amide (GLP-1) enhances insulin-stimulated glucose metabolism in 3T3-L1 adipocytes: one of several potential extrapancreatic sites of GLP-1 action
    Josephine Mary Egan, Chahrzad Montrose‐Rafizadeh, Y Wang, Michel Bernier, Jesse Roth · 1994 · Endocrinology
  135. Protein Kinase A-Dependent Stimulation of Exocytosis in Mouse Pancreatic β-Cells by Glucose-Dependent Insulinotropic Polypeptide
    Wei‐Guang Ding, Jesper Gromada · 1997 · Diabetes
  136. Structure of the human ghicagon gene
    James W. White, Grady F. Saunders · 1986 · Nucleic Acids Research
  137. Elimination of the action of glucagon-like peptide 1 causes an impairment of glucose tolerance after nutrient ingestion by healthy baboons.
    David A. D’Alessio, R Vogel, Ronald L. Prigeon, Ellen C. Laschansky, Donna J. Koerker, John Eng, J W Ensinck · 1996 · Journal of Clinical Investigation
  138. Resistin Is a Key Mediator of Glucose-dependent Insulinotropic Polypeptide (GIP) Stimulation of Lipoprotein Lipase (LPL) Activity in Adipocytes
    Kim, Su-Jin, Nian, Cuilan, McIntosh, Christopher H.S. · 2007 · Journal of Biological Chemistry
  139. Gastrin-releasing peptide is a novel mediator of proximal nutrient- induced proglucagon-derived peptide secretion from the distal gut
    J N Roberge, Karen A. Gronau, Patricia Lee Brubaker · 1996 · Endocrinology
  140. Antagonism of Rat β-Cell Voltage-dependent K+ Currents by Exendin 4 Requires Dual Activation of the cAMP/Protein Kinase A and Phosphatidylinositol 3-Kinase Signaling Pathways
    Patrick E. MacDonald, Xiaolin Wang, Fuzhen Xia, Wasim El-kholy, Elisha D. Targonsky, Robert G. Tsushima, Michael B. Wheeler · 2003 · Journal of Biological Chemistry
  141. Immunohistochemical distribution of glucose‐dependent insulinotropic polypeptide in the adult rat brain
    Jenny Nyberg, Calle Jacobsson, Michelle F. Anderson, Peter S. Eriksson · 2007 · Journal of Neuroscience Research
  142. Identification of the intestinal cell storing gastric inhibitory peptide
    Roberto Buffa, Julia Margaret Polak, A. G. E. Pearse, Enrico Solcia, Lars Grimelius, C. Capella · 1975 · Histochemistry and Cell Biology
  143. Regulatory Role of CD38 (ADP-ribosyl Cyclase/Cyclic ADP-ribose Hydrolase) in Insulin Secretion by Glucose in Pancreatic βCells
    Ichiro Kato, Shin Takasawa, Atsuya Akabane, Osamu Tanaka, Hiroshi Abe, Toshinari Takamura, Yu Suzuki, Koji Nata, Hideto Yonekura, Takashi Yoshimoto et al. · 1995 · Journal of Biological Chemistry
  144. The neurotransmitters glycine and GABA stimulate glucagon‐like peptide‐1 release from the GLUTag cell line
    A. Gameiro, Frank M. Reimann, Abdella M. Habib, Dervla O’Malley, L. Williams, Anna K. Simpson, Fiona Mary Gribble · 2005 · The Journal of Physiology
  145. The vasoconstrictor effect of neuropeptide Y and related peptides in the guinea pig isolated heart
    Francis Rioux, Hélène Bachelard, Jean‐Claude Martel · 1986 · Peptides
  146. Sequence of an intestinal cDNA encoding human gastric inhibitory polypeptide precursor.
    Jun Takeda, Yutaka Seino, Kazuo Tanaka, Hirofumi Fukumoto, Toshiaki Kayano, Hideo Kohka Takahashi, Tadao Mitani, M Kurono, T Suzuki, T Tobe · 1987 · Proceedings of the National Academy of Sciences
  147. Impaired Intestinal Proglucagon Processing in Mice Lacking Prohormone Convertase 1
    Randi Ugleholdt, Xiaorong Zhu, Carolyn Fiona Deacon, Cathrine Ørskov, Donald F. Steiner, Jens Juul Holst · 2003 · Endocrinology
  148. NFAT Regulates Insulin Gene Promoter Activity in Response to Synergistic Pathways Induced by Glucose and Glucagon-Like Peptide-1
    Michael C. Lawrence, Harshika S. Bhatt, Richard A. Easom · 2002 · Diabetes
  149. Identification of glucagon-like peptide 1 (GLP-1) actions essential for glucose homeostasis in mice with disruption of GLP-1 receptor signaling.
    Louise A. Scrocchi, Bess Adkins Marshall, Sonya Cook, Patricia Lee Brubaker, Daniel J. Drucker · 1998 · Diabetes
  150. The Dipeptidyl Peptidase 4 Inhibitor Vildagliptin Does Not Accentuate Glibenclamide-Induced Hypoglycemia but Reduces Glucose-Induced Glucagon-Like Peptide 1 and Gastric Inhibitory Polypeptide Secretion
    Andrea El-Ouaghlidi, Erika Rehring, Jens Juul Holst, Anja Schweizer, James Edward Foley, David Holmes, Michael Albrecht Nauck · 2007 · The Journal of Clinical Endocrinology & Metabolism
  151. Glucagon-like peptide 1 increases insulin sensitivity in depancreatized dogs.
    Harmanjit Sandhu, Stephanie R. Wiesenthal, Patrick E. MacDonald, Richard H. McCall, Vaja Tchipashvili, S Rashid, Malathy Satkunarajah, David M. Irwin, Zhi Qing Shi, PATRICIA L. BRUBAKER et al. · 1999 · Diabetes
  152. Cloning and functional expression of the human glucagon-like peptide-1 (GLP-1) receptor.
    Joseph Stephen Dillon, Yukio Tanizawa, Michael B. Wheeler · 1993 · Endocrinology
  153. Glucagon like peptide-1 (7-36) amide (GLP-1) nerve terminals densely innervate corticotropin-releasing hormone neurons in the hypothalamic paraventricular nucleus
    Sumit Sarkar, Csaba Fekete, Gábor Légrádi, Ronald Michael Lechan · 2003 · Brain Research
  154. Glucagon-Like Peptide-1-(7-36)Amide Is Transformed to Glucagon-Like Peptide-1-(9-36)Amide by Dipeptidyl Peptidase IV in the Capillaries Supplying the L Cells of the Porcine Intestine
    L. Hansen · 1999 · Endocrinology
  155. The pathogenesis of NIDDM involves a defective expression of the GIP receptor
    Jens Juul Holst, Jesper Gromada, Michael Albrecht Nauck · 1997 · Diabetologia
  156. Effects of Ingestion of Triglyceride or Galactose on Secretion of Gastric Inhibitory Polypeptide and on Responses to Intravenous Glucose in Normal and Diabetic Subjects
    S A Ross, John Dupré · 1978 · Diabetes
  157. Exendin-4 modulates diabetes onset in nonobese diabetic mice
    Hadjiyanni, Irene, Baggio, Laurie L., Poussier, Philippe, Drucker, Daniel J. · 2008 · Endocrinology
  158. Improving function and survival of pancreatic islets by endogenous production of glucagon-like peptide 1 (GLP-1)
    Rhonda D. Wideman, Irene L.Y. Yu, Travis D. Webber, C. Bruce Verchere, James D. Johnson, Anthony T. Cheung, Timothy J. Kieffer · 2006 · Proceedings of the National Academy of Sciences
  159. Insulinotropic Properties of Synthetic Human Gastric Inhibitory Polypeptide in Man: Interactions with Glucose, Phenylalanine, and Cholecystokinin-8
    Michael Albrecht Nauck, Wolfgang Ekkehard Schmidt, Reinhold Ebert, JUERGEN STRIETZEL, Per Cantor, Georg E. HOFFMANN, W. Creutzfeldt · 1989 · The Journal of Clinical Endocrinology & Metabolism
  160. Munc13-1 Deficiency Reduces Insulin Secretion and Causes Abnormal Glucose Tolerance
    Edwin P. Kwan, Li Xie, Laura Sheu, Christopher James Nolan, Marc Prentki, Andrea Betz, Nils Brose, Herbert Y. Gaisano · 2006 · Diabetes
  161. Taste Cells of the Gut and Gastrointestinal Chemosensation
    Josephine Mary Egan, Robert F. Margolskee · 2008 · Molecular Interventions
  162. GLUT2 and the incretin receptors are involved in glucose-induced incretin secretion
    Patrice D. Cani, Jens Juul Holst, Daniel J. Drucker, Nathalie M. Delzenne, Bernard Thorens, Rémy Burcelin, Claude Knauf · 2007 · Molecular and Cellular Endocrinology
  163. Glucagon-related peptide 1 (GLP-1): hormone and neurotransmitter
    Philip Just Larsen, Jens Juul Holst · 2004 · Regulatory Peptides
  164. cAMP-Activated Protein Kinase-Independent Potentiation of Insulin Secretion by cAMP Is Impaired in SUR1 Null Islets
    Mitsuhiro Nakazaki, Ana Crane, Min Hu, Victor J. Seghers, Susanne Ullrich, Lydia Aguilar‐Bryan, Joseph Bryan · 2002 · Diabetes
  165. Characterization of the Cellular and Metabolic Effects of a Novel Enzyme-Resistant Antagonist of Glucose-Dependent Insulinotropic Polypeptide
    Victor A. Gault, Finbarr P.M. O'Harte, Patrick Harriott, Peter R. Flatt · 2002 · Biochemical and Biophysical Research Communications
  166. Pharmacokinetics and Pharmacodynamics of Vildagliptin??in??Patients?? with Type??2??Diabetes??Mellitus
    Yanling He, Denise B. Serra, Yibin Wang, Joelle Campestrini, Gilles‐Jacques Rivière, Carolyn Fiona Deacon, Jens Juul Holst, Sherwyn Leon Schwartz, Jace C. Nielsen, Monica Ligueros‐Saylan · 2007 · Clinical Pharmacokinetics
  167. The glucagon superfamily: Precursor structure and gene organization
    Graeme I. Bell · 1986 · Peptides
  168. Glucagon gene transcription is negatively regulated by insulin in a hamster islet cell line.
    Jacques Philippé · 1989 · Journal of Clinical Investigation
  169. Functional receptors for the insulinotropic hormone glucagon‐like peptide‐I(7–37) on a somatostatin secreting cell line
    Hans Christoph Fehmann, Joel Francis Habener · 1991 · FEBS Letters
  170. Abnormalities of GIP in Spontaneous Syndromes of Obesity and Diabetes in Mice
    Peter R. Flatt, Clifford J. Bailey, P. Kwasowski, Sara K. Swanston-Flatt, Vincent Marks · 1983 · Diabetes
  171. Gut hormones in tropical malabsorption.
    Harvey S. Besterman, Gordon C Cook, D. L. Sarson, N.D. Christofides, M G Bryant, Michael Gregor, S.R. Bloom · 1979 · BMJ
  172. Protection of pancreatic β-cells by exendin-4 may involve the reduction of endoplasmic reticulum stress; in vivo and in vitro studies
    Shin Tsunekawa, Naoki Yamamoto, Katsura Tsukamoto, Yuji Itoh, Yukiko Kurohane Kaneko, Toshihide Kimura, Yoh Ariyoshi, Yoshitaka Miura, Yutaka Oiso, Ichiro Niki · 2007 · Journal of Endocrinology
  173. Effects of 3 Months of Continuous Subcutaneous Administration of Glucagon-Like Peptide 1 in Elderly Patients With Type 2 Diabetes
    Graydon S. Meneilly, Nigel H. Greig, Hugh D. Tildesley, Joel Francis Habener, Josephine Mary Egan, Dariush Elahi · 2003 · Diabetes Care
  174. Sensory nerves contribute to insulin secretion by glucagon-like peptide-1 in mice
    Bo Åhrén · 2004 · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology
  175. Cell signalling of the GLP-1 action in rat liver
    Araceli Redondo · 2003 · Molecular and Cellular Endocrinology
  176. Munc13-1 is required for the sustained release of insulin from pancreatic β cells
    Kang, Lijun, He, Zixuan, Xu, Pingyong, Fan, Junmei, Betz, Andrea, Brose, Nils, Xu, Tao · 2006 · Cell Metabolism
  177. Somatostatin-28 regulates GLP-1 secretion via somatostatin receptor subtype 5 in rat intestinal cultures
    Chisholm, Connie, Greenberg, Gordon R. · 2002 · American Journal of Physiology-Endocrinology and Metabolism
  178. Absolute bioavailability of sitagliptin, an oral dipeptidyl peptidase‐4 inhibitor, in healthy volunteers
    Arthur J. Bergman, David L. Ebel, Fang Liu et al. · 2007 · Biopharmaceutics & Drug Disposition
  179. Potential Role for a Regulator of G Protein Signaling (RGS3) in Gonadotropin-Releasing Hormone (GnRH) Stimulated Desensitization
    Jimmy D. Neill, Lennard Wayne Duck, Jeffrey C. Sellers · 1997 · Endocrinology
  180. Exendin‐4 differentiation of a human pancreatic duct cell line into endocrine cells: Involvement of PDX‐1 and HNF3β transcription factors
    Jie Zhou, Marco A. Piñeyro, Xiaolin Wang, Maı̀re E. Doyle, Josephine Mary Egan · 2002 · Journal of Cellular Physiology
  181. Amplification of Insulin Secretion by Lipid Messengers
    J. Turk, R. Gross, S. Ramanadham · 1993 · Diabetes
  182. Role of glucagon-like peptide-1 in the pathogenesis and treatment of diabetes mellitus
    León, Diva D. De, Crutchlow, Michael F., Ham, Jee-Young Nina, Stoffers, Doris A. · 2006 · The International Journal of Biochemistry &amp; Cell Biology
  183. Influence of Gastric Inhibitory Polypeptide Antiserum on Glucose-Induced Insulin Secretion in Rats
    Reinhold Ebert, W. Creutzfeldt · 1982 · Endocrinology
  184. Cellular Engineering and Gene Therapy Strategies for Insulin Replacement in Diabetes
    C. Newgard · 1994 · Diabetes
  185. The hepatic vagal nerve is receptive to incretin hormone glucagon-like peptide-l, but not to glucose-dependent insulinotropic polypeptide, in the portal vein
    Makoto Nishizawa, Hajime Nakabayashi, Kenzo Uchida, Atsushi Nakagaw, Akira Niijima · 1996 · Journal of the Autonomic Nervous System
  186. Human Gastric Inhibitory Polypeptide Receptor: Cloning of the Gene (GIPR) and cDNA
    Yuichiro Yamada, Tadao HAYAMI, KATSUKI NAKAMURA, Pamela J. Kaisaki, Yoshimichi Someya, Changzheng Wang, Susumu Seino, Yutaka Seino · 1995 · Genomics
  187. Different domains in the third intracellular loop of the GLP-1 receptor are responsible for Gαs and Gαi/Gαo activation
    Mattias Hällbrink, Tomas G. Holmqvist, Magnus Olsson, Claes‐Göran Östenson, Suad Efendić, Ülo Langel · 2001 · Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology
  188. A novel pathway for regulation of glucose‐dependent insulinotropic polypeptide receptor expression in β‐cells
    Lynn, Francis C., Thompson, Stephen A., Pospisilik, J. Andrew, Ehses, Jan A., Hinke, Simon A., Pamir, Nathalie, McIntosh, Christopher H. S., Pederson, Raymond A. · 2003 · The FASEB Journal
  189. The glucose dependent insulinotropic polypeptide response to oral glucose and mixed meals is increased in patients with Type 2 (non-insulin-dependent) diabetes mellitus
    Ian Richard Jones, David R. Owens, Stephen D. Luzio, Susan Eileen Isabella Williams, T M Hayes · 1989 · Diabetologia
  190. Effect of GLP-1 treatment on GLUT2 and GLUT4 expression in type 1 and type 2 rat diabetic models
    M. Villanueva-Peñacarrillo, J. Puente, A. Redondo, F. Clemente, I. Valverde · 2001 · Endocrine
  191. Chronic Exposure to GLP-1R Agonists Promotes Homologous GLP-1 Receptor Desensitization In Vitro but Does Not Attenuate GLP-1R–Dependent Glucose Homeostasis In Vivo
    Laurie L. Baggio, Jung‐Guk Kim, Daniel J. Drucker · 2004 · Diabetes
  192. Transcriptional activation of the rat glucagon gene by the cyclic AMP-responsive element in pancreatic islet cells.
    W Knepel, J Chafitz, Joel Francis Habener · 1990 · Molecular and Cellular Biology
  193. The Croonian Lectures ON THE CHEMICAL CORRELATION OF THE FUNCTIONS OF THE BODY.
    1905 · The Lancet
  194. Role of the Vagus Nerve in Mediating Proximal Nutrient-Induced Glucagon-Like Peptide-1 Secretion
    A. S. Rocca · 1999 · Endocrinology
  195. Mechanisms underlying proglucagon gene expression
    Tianru Jin · 2008 · Journal of Endocrinology
  196. Glucose-Dependent Insulinotropic Polypeptide Is a Growth Factor for (INS-1) Cells by Pleiotropic Signaling
    A. Trumper · 2001 · Molecular Endocrinology
  197. Transcriptional Activation of the Proglucagon Gene by Lithium and β-Catenin in Intestinal Endocrine L Cells
    Zuyao Ni, Younès Anini, Xianjun Fang, Gordon Brent Mills, Patricia Lee Brubaker, Tianru Jin · 2003 · Journal of Biological Chemistry
  198. Exendin-4 increases insulin sensitivity via a PI-3-kinase-dependent mechanism: contrasting effects of GLP-1
    ISKANDAR RAUF IDRIS, Divina Patiag, Samuel Gray, Richard Donnelly · 2002 · Biochemical Pharmacology
  199. Gastric Inhibitory Polypeptide (GIP) in Maturity-onset Diabetes Mellitus
    Samuel E. Crockett, Ernest L. Mazzaferri, Samuel Cataland · 1976 · Diabetes
  200. Increasing GLP-1–Induced β-Cell Proliferation by Silencing the Negative Regulators of Signaling cAMP Response Element Modulator-α and DUSP14
    Klinger, Sonia, Poussin, Carine, Debril, Marie-Bernard, Dolci, Wanda, Halban, Philippe A., Thorens, Bernard · 2008 · Diabetes