The Physiology, Signaling, and Pharmacology of Dopamine Receptors

Neurocircuitry of Addiction

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Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B

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EVIDENCE FOR THE EXISTENCE OF MONOAMINE-CONTAINING NEURONS IN THE CENTRAL NERVOUS SYSTEM. I. DEMONSTRATION OF MONOAMINES IN THE CELL BODIES OF BRAIN STEM NEURONS.

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Multiple receptors for dopamine

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Dopamine receptors: from structure to function

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Seven-transmembrane receptors

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NEURAL MECHANISMS OF ADDICTION: The Role of Reward-Related Learning and Memory

Hyman, S. E., Malenka, R. C., & Nestler, E. J. (2006) · Annual Review of Neuroscience · doi:10.1146/annurev.neuro.29.051605.113009 · Cited by 2,647

Molecular cloning and characterization of a novel dopamine receptor (D3) as a target for neuroleptics

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Hyperlocomotion and indifference to cocaine and amphetamine in mice lacking the dopamine transporter

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Dopamine Receptor Binding Predicts Clinical and Pharmacological Potencies of Antischizophrenic Drugs

Creese, I., Burt, D. R., & Snyder, S. H. (1976) · Science · doi:10.1126/science.3854 · Cited by 2,220

The Application of the Open Pharmacological Concepts Triple Store (Open PHACTS) to Support Drug Discovery Research

Ratnam, J., Zdrazil, B., Digles, D., Rodríguez, E. C., Neefs, J., Tipney, H., Siebes, R., Waagmeester, A., Bradley, G., Chau, C. H., et al. (2014) · PLoS ONE · doi:10.1371/journal.pone.0115460 · Cited by 35

Investigation of novel ropinirole analogues: synthesis, pharmacological evaluation and computational analysis of dopamine D 2 receptor functionalized congeners and homobivalent ligands

Jörg, M., Kaczor, A. A., Mak, F. S., Lee, K. C. K., Poso, A., Miller, N. D., Scammells, P. J., & Capuano, B. (2014) · MedChemComm · doi:10.1039/c4md00066h · Cited by 35

New Model of Action for Mood Stabilizers: Phosphoproteome from Rat Pre-Frontal Cortex Synaptoneurosomal Preparations

Corena-McLeod, M. D. P., Walss‐Bass, C., Oliveros, A., Villegas, A. G., Ceballos, C., Charlesworth, C. M., Madden, B. J., Linser, P. J., Ekeris, L. V., Smith, K., et al. (2013) · PLoS ONE · doi:10.1371/journal.pone.0052147 · Cited by 35

NMDA and dopamine D1 receptors within NAc-shell regulate IEG proteins expression in reward circuit during cocaine memory reconsolidation

Li, Y., Ge, S., Li, N., Chen, L., Zhang, S., Wang, J., Wu, H., Wang, X., & Wang, X. (2015) · Neuroscience · doi:10.1016/j.neuroscience.2015.11.063 · Cited by 35

Evidence for neurotoxicity associated with amoxicillin in juvenile rats

Atlı, Ö., Özkay, Ü. D., Ilgın, S., Aydin, T., Akbulut, E. N., & Sener, E. (2015) · Human & Experimental Toxicology · doi:10.1177/0960327115607948 · Cited by 35

Disease-Specific Heteromerization of G-Protein-Coupled Receptors That Target Drugs of Abuse

Gomes, I., Fujita, W., Chandrakala, M. V., & Devi, L. A. (2013) · Progress in molecular biology and translational science · doi:10.1016/b978-0-12-386931-9.00009-x · Cited by 35

Ultrasensitive electrochemiluminescence biosensor for dopamine based on ZnSe, graphene oxide@multi walled carbon nanotube and Ru(bpy)32+

Tian, L., Wang, X., Wu, K., Hu, Y., Wang, Y., & Lu, J. (2019) · Sensors and Actuators B Chemical · doi:10.1016/j.snb.2019.01.161 · Cited by 35

Highly emissive and biocompatible dopamine-derived oligomers as fluorescent probes for chemical detection and targeted bioimaging

Xiong, B., Chen, Y., Shu, Y., Shen, B., Chan, H. N., Chen, Y., Zhou, J., & Wu, H. (2014) · Chemical Communications · doi:10.1039/c4cc06139j · Cited by 34

Dopamine D2receptors' effects on renal inflammation are mediated by regulation of PP2A function

Zhang, Y., Jiang, X., Qin, C., Cuevas, S., José, P. A., & Armando, I. (2015) · American Journal of Physiology-Renal Physiology · doi:10.1152/ajprenal.00453.2014 · Cited by 34

Dopamine D1/D5, But not D2/D3, Receptor Dependency of Synaptic Plasticity at Hippocampal Mossy Fiber Synapses that Is Enabled by Patterned Afferent Stimulation, or Spatial Learning

Hagena, H., & Manahan‐Vaughan, D. (2016) · Frontiers in Synaptic Neuroscience · doi:10.3389/fnsyn.2016.00031 · Cited by 34

Expression of dopamine signaling genes in the post-mortem brain of individuals with mental illnesses is moderated by body mass index and mediated by insulin signaling genes

Mansur, R. B., Fries, G. R., Subramaniapillai, M., Frangou, S., Felice, F. G. D., Rasgon, N., McEwen, B. S., Brietzke, E. M., & McIntyre, R. S. (2018) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2018.10.020 · Cited by 34

Distinct Dopamine D2 Receptor Antagonists Differentially Impact D2 Receptor Oligomerization

Wouters, E., Marín, A. R., Dalton, J. A. R., Giraldo, J., & Stove, C. P. (2019) · International Journal of Molecular Sciences · doi:10.3390/ijms20071686 · Cited by 34

Unraveling correlative roles of dopamine transporter (DAT) and Parkin in Parkinson’s disease (PD) – A road to discovery?

Jayaramayya, K., Iyer, M., Venkatesan, D., Balasubramanian, V., Narayanasamy, A., Subramaniam, M. D., Cho, S., & Vellingiri, B. (2020) · Brain Research Bulletin · doi:10.1016/j.brainresbull.2020.02.001 · Cited by 34

Stretch-Induced Activation of Pannexin 1 Channels Can Be Prevented by PKA-Dependent Phosphorylation

López, X., Escamilla, R., Fernández, P., Duarte, Y., González-Nilo, F. D., Palacios‐Prado, N., Martı́nez, A. D., & Sáez, J. C. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21239180 · Cited by 34

A novel red fluorescence dopamine biosensor selectively detects dopamine in the presence of norepinephrine in vitro

Nakamoto, C., Goto, Y., Tomizawa, Y., Fukata, Y., Fukata, M., Harpsøe, K., Gloriam, D. E. I., Aoki, K., & Takeuchi, T. (2021) · Molecular Brain · doi:10.1186/s13041-021-00882-8 · Cited by 34

Dopamine as a Potential Target for Learning and Memory: Contributing to Related Neurological Disorders

Kourosh‐Arami, M., Komaki‬, A., & Zarrindast, M. (2022) · CNS & Neurological Disorders - Drug Targets · doi:10.2174/1871527321666220418115503 · Cited by 35

Disruption of Dopamine Receptor 1 Localization to Primary Cilia Impairs Signaling in Striatal Neurons

Stubbs, T., Koemeter-Cox, A., Bingman, J. I., Zhao, F., Kalyanasundaram, A., Rowland, L. A., Periasamy, M., Carter, C. S., Sheffield, V. C., Askwith, C. C., et al. (2022) · Journal of Neuroscience · doi:10.1523/jneurosci.0497-22.2022 · Cited by 34

Neurotoxicity induced by the pyrethroid lambda-cyhalothrin: Alterations in monoaminergic systems and dopaminergic and serotoninergic pathways in the rat brain

López-Torres, B., Arés, I., Martínez, M., Maximiliano, J.-E., Martínez‐Larrañaga, M., Anadón, A., & Martínez, M. (2022) · Food and Chemical Toxicology · doi:10.1016/j.fct.2022.113434 · Cited by 34

Light-driven micromotor swarm induced in-situ polymerization and synergistic photothermal therapy

Li, Z., Fu, S., Li, H., Chen, B., Xie, D., Fu, D., Feng, Y., Gao, C., Liu, S., Wilson, D. A., et al. (2023) · Chemical Engineering Journal · doi:10.1016/j.cej.2023.143393 · Cited by 34

Dopaminergic tone regulates transient potassium current maximal conductance through a translational mechanism requiring D1Rs, cAMP/PKA, Erk and mTOR

Rodgers, E. W., Krenz, W. C., Jiang, X., Li, L., & Baro, D. J. (2013) · BMC Neuroscience · doi:10.1186/1471-2202-14-143 · Cited by 34

TRPV currents and their role in the nociception and neuroplasticity

Satheesh, N. J., Uehara, Y., Fedotova, J., Pohanka, M., Büsselberg, D., & Kružliak, P. (2016) · Neuropeptides · doi:10.1016/j.npep.2016.01.003 · Cited by 34

Walking facilitates positive affect (even when expecting the opposite).

Miller, J. C., & Križan, Z. (2016) · Emotion · doi:10.1037/a0040270 · Cited by 34

Dopamine-2 receptor extracellular N-terminus regulates receptor surface availability and is the target of human pathogenic antibodies from children with movement and psychiatric disorders

Sinmaz, N., Tea, F., Pilli, D., Zou, A., Amatoury, M., Nguyen, T. T.-T. N., Merheb, V., Ramanathan, S., Cooper, S. T., Dale, R. C., et al. (2016) · Acta Neuropathologica Communications · doi:10.1186/s40478-016-0397-1 · Cited by 34

A fresh look at cortical dopamine D2 receptor expressing neurons

Quintana, C., & Beaulieu, J. (2018) · Pharmacological Research · doi:10.1016/j.phrs.2018.12.001 · Cited by 34

Bromophenols from Symphyocladia latiuscula Target Human Monoamine Oxidase and Dopaminergic Receptors for the Management of Neurodegenerative Diseases

Paudel, P., Park, S. E., Seong, S. H., Jung, H. A., & Choi, J. S. (2020) · Journal of Agricultural and Food Chemistry · doi:10.1021/acs.jafc.0c00007 · Cited by 34

Advances in the Therapeutic Use of Non-Ergot Dopamine Agonists in the Treatment of Motor and Non-Motor Symptoms of Parkinson’s Disease

Jing, X., Yang, H., Taximaimaiti, R., & Wang, X. (2022) · Current Neuropharmacology · doi:10.2174/1570159x20666220915091022 · Cited by 33

Hippocampal synaptic failure is an early event in experimental parkinsonism with subtle cognitive deficit

Belloso-Iguerategui, A., Zamarbide, M., Merino-Galán, L., Rodríguez-Chinchilla, T., Gago, B., Santamaría, E., Fernández‐Irigoyen, J., Cotman, C. W., Prieto, G. A., Quiroga‐Varela, A., et al. (2023) · Brain · doi:10.1093/brain/awad227 · Cited by 33

Chronic administration of cholesterol oximes in mice increases transcription of cytoprotective genes and improves transcriptome alterations induced by alpha-synuclein overexpression in nigrostriatal dopaminergic neurons

Richter, F., Gao, F., Medvedeva, V. P., Lee, P. C., Bove, N., Fleming, S. M., Michaud, M., Lemesre, V., Patassini, S., Rosa, K. D. L., et al. (2014) · Neurobiology of Disease · doi:10.1016/j.nbd.2014.05.012 · Cited by 33

COMT and ANKK1 Genetics Interact With Depression to Influence Behavior Following Severe TBI

Myrga, J. M., Juengst, S. B., Failla, M. D., Conley, Y. P., Arenth, P. M., Grace, A. A., & Wagner, A. K. (2016) · Neurorehabilitation and neural repair · doi:10.1177/1545968316648409 · Cited by 33

NCS-Rapgef2, the Protein Product of the NeuronalRapgef2Gene, Is a Specific Activator of D1 Dopamine Receptor-Dependent ERK Phosphorylation in Mouse Brain

Jiang, S. Z., Xu, W., Emery, A. C., Gerfen, C. R., Eiden, M. V., & Eiden, L. E. (2017) · eNeuro · doi:10.1523/eneuro.0248-17.2017 · Cited by 33

The effects of single-dose injections of modafinil and methamphetamine on epigenetic and functional markers in the mouse medial prefrontal cortex: potential role of dopamine receptors

González, B., Torres, O. V., Jayanthi, S., Gomez, N. V., Sosa, M. H., Bernardi, A., Urbano, F. J., García‐Rill, E., Cadet, J. L., & Bisagno, V. (2018) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2018.07.019 · Cited by 33

Eckol as a Potential Therapeutic against Neurodegenerative Diseases Targeting Dopamine D3/D4 Receptors

Paudel, P., Seong, S. H., Wu, S., Park, S. H., Jung, H. A., & Choi, J. S. (2019) · Marine Drugs · doi:10.3390/md17020108 · Cited by 33

Forebrain Dopamine System Regulates Inner Ear Auditory Sensitivity to Socially Relevant Acoustic Signals

Perelmuter, J. T., Wilson, A. B., Sisneros, J. A., & Forlano, P. M. (2019) · Current Biology · doi:10.1016/j.cub.2019.05.055 · Cited by 33

Selective D2 and D3 receptor antagonists oppositely modulate cocaine responses in mice via distinct postsynaptic mechanisms in nucleus accumbens

Manvich, D. F., Petko, A. K., Branco, R. C., Foster, S. L., Porter‐Stransky, K. A., Stout, K. A., Newman, A. H., Miller, G. W., Paladini, C. A., & Weinshenker, D. (2019) · Neuropsychopharmacology · doi:10.1038/s41386-019-0371-2 · Cited by 33

Heterogeneity of dopamine release sites in health and degeneration

Lebowitz, J. J., & Khoshbouei, H. (2019) · Neurobiology of Disease · doi:10.1016/j.nbd.2019.104633 · Cited by 33

Crystal structure of dopamine receptor D4 bound to the subtype selective ligand, L745870

Zhou, Y., Cao, C., He, L., Wang, X., & Zhang, X. C. (2019) · eLife · doi:10.7554/elife.48822 · Cited by 33

Photoactivatable Dopamine and Sulpiride to Explore the Function of Dopaminergic Neurons and Circuits

Asad, N., McLain, D. E., Condon, A. F., Gore, S., Hampton, S. E., Vijay, S., Williams, J. T., & Dore, T. M. (2020) · ACS Chemical Neuroscience · doi:10.1021/acschemneuro.9b00675 · Cited by 33

Immunomodulatory effect and clinical outcome in Parkinson's disease patients on levodopa-pramipexole combo therapy: A two-year prospective study

Espinosa-Cárdenas, R., Arce-Sillas, A., Álvarez‐Luquín, D. D., Leyva-Hernández, J., Montes-Moratilla, E. U., Gonzalez-Saavedra, I., Boll, M., García-García, E., Ángeles-Perea, S., Fragoso, G., et al. (2020) · Journal of Neuroimmunology · doi:10.1016/j.jneuroim.2020.577328 · Cited by 33

Epidermal growth factor receptor as a molecular determinant of glioblastoma response to dopamine receptor D2 inhibitors

He, Y., Li, J., Koga, T., Ma, J., Dhawan, S., Suzuki, Y., Furnari, F. B., Prabhu, V. V., Allen, J. E., & Chen, C. C. (2020) · Neuro-Oncology · doi:10.1093/neuonc/noaa188 · Cited by 33

Neuroprotective effects of Tongtian oral liquid, a Traditional Chinese Medicine in the Parkinson's disease-induced zebrafish model

Shan, D., Rajendran, R. S., Xia, Q., She, G., Tu, P., Zhang, Y., & Liu, K. (2022) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2022.112706 · Cited by 34

Food craving-like episodes during pregnancy are mediated by accumbal dopaminergic circuits

Haddad-Tóvolli, R., Ramírez, S., Muñoz‐Moreno, E., Milà‐Guasch, M., Miquel-Rio, L., Pozo, M., Chivite, Í., Altirriba, J., Obri, A., Gómez-Valadés, A. G., et al. (2022) · Nature Metabolism · doi:10.1038/s42255-022-00557-1 · Cited by 33

Recent advances in dopamine D 2 receptor ligands in the treatment of neuropsychiatric disorders

Jůza, R., Musílek, K., Mezeiová, E., Soukup, O., & Korábečný, J. (2022) · Medicinal Research Reviews · doi:10.1002/med.21923 · Cited by 34

Mood and behavior regulation: interaction of lithium and dopaminergic system

Mohamadian, M., Fallah, H., Ghofrani-Jahromi, Z., Rahimi-Danesh, M., Saadlou, M.-S. S. Q., & Vaseghi, S. (2023) · Naunyn-Schmiedeberg s Archives of Pharmacology · doi:10.1007/s00210-023-02437-1 · Cited by 33

Lithium engages autophagy for neuroprotection and neuroplasticity: Translational evidence for therapy

Puglisi‐Allegra, S., Lazzeri, G., Busceti, C. L., Giorgi, F. S., Biagioni, F., & Fornai, F. (2023) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2023.105148 · Cited by 33

Structure and function of G protein‐coupled receptor oligomers: implications for drug discovery

Schonenbach, N. S., Hussain, S., & O’Malley, M. (2014) · Wiley Interdisciplinary Reviews Nanomedicine and Nanobiotechnology · doi:10.1002/wnan.1319 · Cited by 33

Biogenic amines and the control of neuromuscular signaling in schistosomes

Ribeiro, P., Gupta, V., & El‐Sakkary, N. (2012) · Invertebrate Neuroscience · doi:10.1007/s10158-012-0132-y · Cited by 33

Early postnatal experience and DRD2 genotype affect dopamine receptor expression in the rat ventral striatum

Lovic, V., Belay, H. T., Walker, C., Burton, C. L., Meaney, M. J., Sokolowski, M. B., & Fleming, A. S. (2012) · Behavioural Brain Research · doi:10.1016/j.bbr.2012.09.046 · Cited by 33

Aberrant CaMKII activity in the medial prefrontal cortex is associated with cognitive dysfunction in ADHD model rats

Yabuki, Y., Shioda, N., Maeda, T., Hiraide, S., Togashi, H., & Fukunaga, K. (2014) · Brain Research · doi:10.1016/j.brainres.2014.02.025 · Cited by 33

Dopaminergic Modulation of GABAergic Transmission in the Entorhinal Cortex: Concerted Roles of 1 Adrenoreceptors, Inward Rectifier K+, and T-Type Ca2+ Channels

Cilz, N. I., Kurada, L., Hu, B., & Lei, S. (2013) · Cerebral Cortex · doi:10.1093/cercor/bht177 · Cited by 33

Electrochemical oxidation of catecholamines on fluorine-doped SnO2 substrates. Square-wave voltammetric method for methyldopa determination in pharmaceutical dosage forms

Ramirez, C. G., del Valle, M. A., Isaacs, M. A., & Armijo, F. (2016) · Electrochimica Acta · doi:10.1016/j.electacta.2016.03.093 · Cited by 33

Evidence of sexual dimorphism in D1 and D2 dopaminergic receptors expression in frontal cortex and striatum of young rats

Orendain-Jaime, E. N., Ortega‐Ibarra, J., & López‐Pérez, S. J. (2016) · Neurochemistry International · doi:10.1016/j.neuint.2016.09.001 · Cited by 33

Endocytosis following dopamine D2 receptor activation is critical for neuronal activity and dendritic spine formation via Rabex-5/PDGFRβ signaling in striatopallidal medium spiny neurons

Shioda, N., Yabuki, Y., Wang, Y., Uchigashima, M., Hikida, T., Sasaoka, T., Mori, H., Watanabe, M., Sasahara, M., & Fukunaga, K. (2016) · Molecular Psychiatry · doi:10.1038/mp.2016.200 · Cited by 33

Role of Dopamine D2/D3 Receptors in Development, Plasticity, and Neuroprotection in Human iPSC-Derived Midbrain Dopaminergic Neurons

Bono, F., Savoia, P., Guglielmi, A., Gennarelli, M., Piovani, G., Sigala, S., Leo, D., Espinoza, S., Gainetdinov, R. R., Devoto, P., et al. (2017) · Molecular Neurobiology · doi:10.1007/s12035-016-0376-3 · Cited by 34

The DRD2 rs1076560 polymorphism and schizophrenia-related intermediate phenotypes: A systematic review and meta-analysis

Luykx, J. J., Broersen, J. L., & de Leeuw, M. (2017) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2017.01.006 · Cited by 33

The structural determinants of the bitopic binding mode of a negative allosteric modulator of the dopamine D 2 receptor

Draper-Joyce, C. J., Michino, M., Verma, R. K., Herenbrink, C. K., Shonberg, J., Kopinathan, A., Scammells, P. J., Capuano, B., Thal, D. M., Javitch, J. A., et al. (2018) · Biochemical Pharmacology · doi:10.1016/j.bcp.2018.01.002 · Cited by 33

Dopamine D4 Receptor-Selective Compounds Reveal Structure–Activity Relationships that Engender Agonist Efficacy

Keck, T. M., Free, R. B., Day, M. M., Brown, S. L., Maddaluna, M. S., Fountain, G., Cooper, C., Fallon, B., Holmes, M. D., Stang, C. R. T., et al. (2019) · Journal of Medicinal Chemistry · doi:10.1021/acs.jmedchem.9b00231 · Cited by 33

Dopamine Receptor Expression Among Local and Visual Cortex-Projecting Frontal Eye Field Neurons

Mueller, A. L., Krock, R. M., Shepard, S. B., & Moore, T. (2019) · Cerebral Cortex · doi:10.1093/cercor/bhz078 · Cited by 33

A mechanistic model of ADHD as resulting from dopamine phasic/tonic imbalance during reinforcement learning

Véronneau-Veilleux, F., Robaey, P., Ursino, M., & Nekka, F. (2022) · Frontiers in Computational Neuroscience · doi:10.3389/fncom.2022.849323 · Cited by 32

Laser Scribing Turns Plastic Waste into a Biosensor via the Restructuration of Nanocarbon Composites for Noninvasive Dopamine Detection

Suriyaprakash, J., Huang, Y., Hu, Z., Wang, H., Zhan, Y., Zhou, Y., Thangavelu, I., & Wu, L. (2023) · Biosensors · doi:10.3390/bios13080810 · Cited by 32

Anti-Inflammatory Effects of Peripheral Dopamine

Moore, S. C., de Castro, P. A. S. V., Yaqub, D., José, P. A., & Armando, I. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms241813816 · Cited by 32

Dopaminergic circuits controlling threat and safety learning

Duvarci, S. (2024) · Trends in Neurosciences · doi:10.1016/j.tins.2024.10.001 · Cited by 32

Three Mechanisms by which Striatal Denervation Causes Breakdown of Dopamine Signaling

Dreyer, J. K. (2014) · Journal of Neuroscience · doi:10.1523/jneurosci.1458-14.2014 · Cited by 32

Selective Expression of a Dominant-Negative Type Ια PKA Regulatory Subunit in Striatal Medium Spiny Neurons Impairs Gene Expression and Leads to Reduced Feeding and Locomotor Activity

Yang, L., Gilbert, M. L., Zheng, R., & McKnight, G. S. (2014) · Journal of Neuroscience · doi:10.1523/jneurosci.3460-13.2014 · Cited by 32

Cariprazine exerts antimanic properties and interferes with dopamine D2 receptor β‐arrestin interactions

Gao, Y., Peterson, S. M., Masri, B., Hougland, M. T., Adham, N., Gyertyán, I., Kiss, B., Caron, M. G., & El‐Mallakh, R. S. (2014) · Pharmacology Research & Perspectives · doi:10.1002/prp2.73 · Cited by 32

Pharmacological and signalling properties of a D2-like dopamine receptor (Dop3) in Tribolium castaneum

Verlinden, H., Vleugels, R., Verdonck, R., Urlacher, E., Broeck, J. V., & Mercer, A. R. (2014) · Insect Biochemistry and Molecular Biology · doi:10.1016/j.ibmb.2014.11.002 · Cited by 32

Effects of methylphenidate on the aggressive behavior, serotonin and dopamine levels, and dopamine-related gene transcription in brain of male Nile tilapia (Oreochromis niloticus)

Batalhão, I. G., Lima, D., Russi, A. P. M., Boscolo, C. N. P., da Silva, D. G. H., Pereira, T. S. B., Bainy, A. C. D., & de Almeida, E. A. (2019) · Fish Physiology and Biochemistry · doi:10.1007/s10695-019-00645-2 · Cited by 32

Aptamer-based electrochemical biosensors

Shadman, S. M., Daneshi, M., Shafiei, F., Azimimehr, M., Khorasgani, M. R., Sadeghian, M., Motaghi, H., & Mehrgardi, M. A. (2019) · Elsevier eBooks · doi:10.1016/b978-0-12-816491-4.00008-5 · Cited by 32

Chronic exposure to methylmercury induces puncta formation in cephalic dopaminergic neurons in Caenorhabditis elegans

Ke, T., Tsatsakis, A. M., Santamarı́a, A., Soares, F. A. A., Tinkov, A. A., Docea, A. O., Skalny, A. V., Bowman, A. B., & Aschner, M. (2020) · NeuroToxicology · doi:10.1016/j.neuro.2020.01.003 · Cited by 32

The KBTBD6/7-DRD2 axis regulates pituitary adenoma sensitivity to dopamine agonist treatment

Liu, Y. T., Liu, F., Cao, L., Li, X., Gu, W. T., Zheng, Y. Z., Tang, H., Wang, Y., Yao, H. W., Zhang, Y., et al. (2020) · Acta Neuropathologica · doi:10.1007/s00401-020-02180-4 · Cited by 32

Current and emerging therapeutic targets for Parkinson’s disease

Pingale, T. D., & Gupta, G. L. (2020) · Metabolic Brain Disease · doi:10.1007/s11011-020-00636-w · Cited by 32

Aging-related modifications to G protein-coupled receptor signaling diversity

van Gastel, J., Leysen, H., Boddaert, J., Vangenechten, L., Luttrell, L. M., Martin, B., & Maudsley, S. R. (2020) · Pharmacology & Therapeutics · doi:10.1016/j.pharmthera.2020.107793 · Cited by 32

The dopamine D1–D2DR complex in the rat spinal cord promotes neuropathic pain by increasing neuronal excitability after chronic constriction injury

Bao, Y., Dai, W., Fan, J.-F., Ma, B., Li, S., Zhao, W., Yu, B., & Liu, J.-H. (2021) · Experimental & Molecular Medicine · doi:10.1038/s12276-021-00563-5 · Cited by 32

UEG Week 2018 Poster Presentations

Pittet, V., Aslan, N., Fournier, N., Decollogny, A., Schoepfer, A., Seibold, F., & Rodondi, P. Y. (2018) · United European Gastroenterology Journal · doi:10.1177/2050640618792819 · Cited by 32

A portable and sensitive dopamine sensor based on AuNPs functionalized ZnO-rGO nanocomposites modified screen-printed electrode

Gu, M., Xiao, H., Wei, S., Chen, Z., & Cao, L. (2022) · Journal of Electroanalytical Chemistry · doi:10.1016/j.jelechem.2022.116117 · Cited by 32

Chronobiology of Parkinson's disease: Past, present and future

Asadpoordezaki, Z., Coogan, A. N., & Henley, B. M. (2022) · European Journal of Neuroscience · doi:10.1111/ejn.15859 · Cited by 32

Exploring the underlying mechanisms of drug‐induced impulse control disorders: a pharmacovigilance‐pharmacodynamic study

Fusaroli, M., Giunchi, V., Battini, V., Gringeri, M., Rimondini, R., Menchetti, M., Radice, S., Pozzi, M., Nobile, M., Clementi, E., et al. (2022) · Psychiatry and Clinical Neurosciences · doi:10.1111/pcn.13511 · Cited by 32

Dopamine D2 receptor agonist Bromocriptine ameliorates Aβ1-42-induced memory deficits and neuroinflammation in mice

Liu, X., Cheng, Z.-Y., Li, Y.-F., Liu, C., Wang, C., Gong, X., & He, L. (2022) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2022.175443 · Cited by 32

Dissociable effects of dopamine on learning and performance within sensorimotor striatum

Leventhal, D., Stoetzner, C. R., Abraham, R., Pettibone, J. R., DeMarco, K., & Berke, J. D. (2013) · Basal Ganglia · doi:10.1016/j.baga.2013.11.001 · Cited by 32

Signalling profile differences: paliperidone versus risperidone

Clarke, W. P., Chavera, T. A., Silva, M., Sullivan, L. C., & Berg, K. A. (2013) · British Journal of Pharmacology · doi:10.1111/bph.12295 · Cited by 32

Dopamine Receptor Gene (DRD1-DRD5) Expression Changes as Stress Factors Associated with Breast Cancer

Pornour, M., Ahangari, G., Hejazi, S. H., Ahmadkhaniha, H., & Akbari, M. (2015) · Asian Pacific Journal of Cancer Prevention · doi:10.7314/apjcp.2014.15.23.10339 · Cited by 32

Dopamine D3 autoreceptor inhibition enhances cocaine potency at the dopamine transporter

McGinnis, M. M., Siciliano, C. A., & Jones, S. R. (2016) · Journal of Neurochemistry · doi:10.1111/jnc.13732 · Cited by 32

G-protein coupled receptors as therapeutic targets for neurodegenerative and cerebrovascular diseases

Guerram, M., Zhang, L., & Jiang, Z. (2016) · Neurochemistry International · doi:10.1016/j.neuint.2016.09.005 · Cited by 32

Metabolomics approach reveals metabolic disorders and potential biomarkers associated with the developmental toxicity of tetrabromobisphenol A and tetrachlorobisphenol A

Ye, G., Chen, Y., Wang, H., Ye, T., Lin, Y., Huang, Q., Chi, Y., & Dong, S. (2016) · Scientific Reports · doi:10.1038/srep35257 · Cited by 32

Contrasting Regulation of Catecholamine Neurotransmission in the Behaving Brain: Pharmacological Insights from an Electrochemical Perspective

Fox, M. E., & Wightman, R. M. (2016) · Pharmacological Reviews · doi:10.1124/pr.116.012948 · Cited by 32

Newly Developed Dopamine D3 Receptor Antagonists, R-VK4-40 and R-VK4-116, Do Not Potentiate Cardiovascular Effects of Cocaine or Oxycodone in Rats

Jordan, C. J., Humburg, B. A., Thorndike, E. B., Shaik, A. B., Xi, Z., Baumann, M. H., Newman, A. H., & Schindler, C. W. (2019) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1124/jpet.119.259390 · Cited by 32

Dopamine Supersensitivity: A Novel Hypothesis of Opioid-Induced Neurobiological Mechanisms Underlying Opioid-Stimulant Co-use and Opioid Relapse

Strickland, J. C., Gipson, C. D., & Dunn, K. E. (2022) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2022.835816 · Cited by 31

Dopamine induces fear extinction by activating the reward-responding amygdala neurons

Zhang, X., Flick, K., Rizzo, M., Pignatelli, M., & Tonegawa, S. (2025) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2501331122 · Cited by 31

Carbon thin films as electrode material in neural sensing

Kaivosoja, E., Sainio, S., Lyytinen, J., Palomäki, T., Laurila, T. T., Kim, S.-I., Han, J. G., & Koskinen, J. (2014) · Surface and Coatings Technology · doi:10.1016/j.surfcoat.2014.07.056 · Cited by 31

D5 dopamine receptor decreases NADPH oxidase, reactive oxygen species and blood pressure via heme oxygenase-1

Lu, Q., Yang, Y., Villar, V. A. M., Asico, L. D., Jones, J. E., Yu, P., Li, H., Weinman, E. J., Eisner, G. M., & José, P. A. (2013) · Hypertension Research · doi:10.1038/hr.2013.9 · Cited by 31

Design, synthesis, and pharmacological evaluation of novel tetrahydroprotoberberine derivatives: Selective inhibitors of dopamine D1 receptor

Qian, W., Lu, W., Sun, H., Li, Z., Zhu, L., Zhao, R., Zhang, L. J., Zhou, S., Zhou, Y., Jiang, H., et al. (2012) · Bioorganic & Medicinal Chemistry · doi:10.1016/j.bmc.2012.05.057 · Cited by 31

Modeling and protein engineering studies of active and inactive states of human dopamine D2 receptor (D2R) and investigation of drug/receptor interactions

Salmas, R. E., Yurtsever, M., Stein, M., & Durdağı, S. (2015) · Molecular Diversity · doi:10.1007/s11030-015-9569-3 · Cited by 31

Differential effects of dopamine D1 and D2/3 receptor antagonism on motor responses

Tran, S., Nowicki, M., Muraleetharan, A., & Gerlai, R. T. (2014) · Psychopharmacology · doi:10.1007/s00213-014-3713-0 · Cited by 31

D2-Dopaminergic Receptor-Linked Pathways: Critical Regulators of CYP3A, CYP2C, and CYP2D

Daskalopoulos, E. P., Lang, M. A., Μαρσέλος, Μ., Malliou, F., & Konstandi, M. (2012) · Molecular Pharmacology · doi:10.1124/mol.112.078709 · Cited by 31

Altered dopaminergic regulation of the dorsal striatum is able to induce tic-like movements in juvenile rats

Nespoli, E., Rizzo, F. R., Boeckers, T. M., Schulze, U., & Hengerer, B. (2018) · PLoS ONE · doi:10.1371/journal.pone.0196515 · Cited by 31

Dopamine D1 receptor signalling in dyskinetic Parkinsonian rats revealed by fiber photometry using FRET-based biosensors

Jones-Tabah, J., Mohammad, H., Hadj-Youssef, S., Kim, L., Martin, R., Benaliouad, F., Tanny, J. C., Clarke, P. B. S., & Hébert, T. E. (2020) · Scientific Reports · doi:10.1038/s41598-020-71121-8 · Cited by 31

Understanding How Physical Exercise Improves Alzheimer’s Disease: Cholinergic and Monoaminergic Systems

Zong, B., Yu, F., Zhang, X., Zhao, W., Sun, P., Li, S., & Li, L. (2022) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2022.869507 · Cited by 31

Histone Deacetylases as Epigenetic Targets for Treating Parkinson’s Disease

Li, Y., Gu, Z., Lin, S., Chen, L., Dzreyan, V., Eid, M., Demyanenko, S. V., & He, B. (2022) · Brain Sciences · doi:10.3390/brainsci12050672 · Cited by 31

Long-term memory, synaptic plasticity and dopamine in rodent medial prefrontal cortex: Role in executive functions

Sheynikhovich, D., Otani, S., Bai, J., & Arleo, A. (2023) · Frontiers in Behavioral Neuroscience · doi:10.3389/fnbeh.2022.1068271 · Cited by 31

Exploring the Role of Neurotransmitters in Multiple Sclerosis: An Expanded Review

Akyüz, E., Celik, B. R., Aslan, F. Ş., Sahin, H., & Angelopoulou, E. (2023) · ACS Chemical Neuroscience · doi:10.1021/acschemneuro.2c00589 · Cited by 32

Dopaminergic Modulation of Prefrontal Cortex Inhibition

Domenico, D. D., & Mapelli, L. (2023) · Biomedicines · doi:10.3390/biomedicines11051276 · Cited by 31

Dopamine receptors – IUPHAR R eview 13

Beaulieu, J., Espinoza, S., & Gainetdinov, R. R. (2014) · British Journal of Pharmacology · doi:10.1111/bph.12906 · Cited by 561

Structure and function of dopamine receptors

Vallone, D., Picetti, R., & Borrelli, E. (2000) · Neuroscience & Biobehavioral Reviews · doi:10.1016/s0149-7634(99)00063-9 · Cited by 857

[Dopamine receptors--structure, characterization and function].

Zawilska, J. B. (2003) · PubMed · Cited by 8

The dopamine D4 receptor: one decade of research

Oak, J. N., Oldenhof, J., & Tol, H. H. M. V. (2000) · European Journal of Pharmacology · doi:10.1016/s0014-2999(00)00562-8 · Cited by 421

Dopamine: Functions, Signaling, and Association with Neurological Diseases

Klein, M. O., Battagello, D. S., Cardoso, A. R., Hauser, D. N., Bittencourt, J. C., & Correa, R. G. (2019) · Cellular and Molecular Neurobiology · doi:10.1007/s10571-018-0632-3 · Cited by 1,073