The Physiology, Signaling, and Pharmacology of Dopamine Receptors

Neurocircuitry of Addiction

Koob, G. F., & Volkow, N. D. (2010) · Neuropsychopharmacology · doi:10.1038/npp.2009.110 · Cited by 5,340

Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B

Cross, D. A. E., Alessi, D. R., Cohen, P., Andjelkovich, M., & Hemmings, B. A. (1995) · Nature · doi:10.1038/378785a0 · Cited by 5,244

EVIDENCE FOR THE EXISTENCE OF MONOAMINE-CONTAINING NEURONS IN THE CENTRAL NERVOUS SYSTEM. I. DEMONSTRATION OF MONOAMINES IN THE CELL BODIES OF BRAIN STEM NEURONS.

Dahlstroem, A., & Fuxé, K. (1964) · PubMed · Cited by 5,133

Multiple receptors for dopamine

Kebabian, J. W., & Calne, D. B. (1979) · Nature · doi:10.1038/277093a0 · Cited by 3,756

Dopamine receptors: from structure to function

MISSALE, C., NASH, S. R., ROBINSON, S. W., JABER, M., & CARON, M. G. (1998) · Physiological Reviews · doi:10.1152/physrev.1998.78.1.189 · Cited by 3,633

Seven-transmembrane receptors

Pierce, K. L., Premont, R. T., & Lefkowitz, R. J. (2002) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm908 · Cited by 2,712

NEURAL MECHANISMS OF ADDICTION: The Role of Reward-Related Learning and Memory

Hyman, S. E., Malenka, R. C., & Nestler, E. J. (2006) · Annual Review of Neuroscience · doi:10.1146/annurev.neuro.29.051605.113009 · Cited by 2,647

Molecular cloning and characterization of a novel dopamine receptor (D3) as a target for neuroleptics

Sokoloff, P., Bruno Giros, A., Martres, M., Bouthenet, M.-L., & Schwartz, J. (1990) · Nature · doi:10.1038/347146a0 · Cited by 2,608

Hyperlocomotion and indifference to cocaine and amphetamine in mice lacking the dopamine transporter

Giros, B., Jaber, M., Jones, S. R., Wightman, R. M., & Caron, M. G. (1996) · Nature · doi:10.1038/379606a0 · Cited by 2,476

Dopamine Receptor Binding Predicts Clinical and Pharmacological Potencies of Antischizophrenic Drugs

Creese, I., Burt, D. R., & Snyder, S. H. (1976) · Science · doi:10.1126/science.3854 · Cited by 2,220

Long-term treatment with l-DOPA and an mGlu5 receptor antagonist prevents changes in brain basal ganglia dopamine receptors, their associated signaling proteins and neuropeptides in parkinsonian monkeys

Morin, N., Jourdain, V. A., Morissette, M., Grégoire, L., & Paolo, T. D. (2014) · Neuropharmacology · doi:10.1016/j.neuropharm.2014.01.014 · Cited by 31

Enzymatic-reaction induced production of polydopamine nanoparticles for sensitive and visual sensing of urea

Li, N., Wang, H., Thia, L., Wang, J., & Wang, X. (2014) · The Analyst · doi:10.1039/c4an01900h · Cited by 31

(-)-Stepholidine is a potent pan-dopamine receptor antagonist of both G protein- and β-arrestin-mediated signaling

Meade, J. A., Free, R. B., Miller, N., Chun, L. S., Doyle, T. B., Moritz, A. E., Conroy, J., Watts, V. J., & Sibley, D. R. (2014) · Psychopharmacology · doi:10.1007/s00213-014-3726-8 · Cited by 31

Adolescent exposure to cocaine, amphetamine, and methylphenidate cross-sensitizes adults to methamphetamine with drug- and sex-specific effects

Shanks, R. A., Ross, J. M., Doyle, H. H., Helton, A., Picou, B. D., Schulz, J., Tavares, C., Bryant, S., Dawson, B. L., & Lloyd, S. A. (2014) · Behavioural Brain Research · doi:10.1016/j.bbr.2014.12.002 · Cited by 31

Pharmacological analysis of dopamine modulation in theDrosophila melanogasterlarval heart

Titlow, J., Rufer, J. M., King, K. E., & Cooper, R. L. (2013) · Physiological Reports · doi:10.1002/phy2.20 · Cited by 31

A Novel Developmental Role for Dopaminergic SigNAling to Specify Hypothalamic Neurotransmitter Identity

Chen, Y., Semenova, S. A., Rozov, S. V., Sundvik, M., Bonkowsky, J. L., & Panula, P. (2016) · Journal of Biological Chemistry · doi:10.1074/jbc.m115.697466 · Cited by 31

RasGRP1 promotes amphetamine-induced motor behavior through a Rhes interaction network (“Rhesactome”) in the striatum

Shahani, N., Swarnkar, S., Giovinazzo, V., Morgenweck, J., Bohn, L., Scharager-Tapia, C., Pascal, B. D., Martínez-Acedo, P., Khare, K., & Subramaniam, S. (2016) · Science Signaling · doi:10.1126/scisignal.aaf6670 · Cited by 31

Dopamine D1 Receptor Immunoreactivity on Fine Processes of GFAP-Positive Astrocytes in the Substantia Nigra Pars Reticulata of Adult Mouse

Nagatomo, K., Suga, S., Saitoh, M., Kogawa, M., Kobayashi, K., Yamamoto, Y., & Yamada, K. (2017) · Frontiers in Neuroanatomy · doi:10.3389/fnana.2017.00003 · Cited by 31

Alterations and interactions of subcortical modulatory systems in Alzheimer's disease

Leko, M. B., Hof, P. R., & Šimić, G. (2021) · Progress in brain research · doi:10.1016/bs.pbr.2020.07.016 · Cited by 31

Changing the Cortical Conductor’s Tempo: Neuromodulation of the Claustrum

Wong, K. L. L., Nair, A., & Augustine, G. J. (2021) · Frontiers in Neural Circuits · doi:10.3389/fncir.2021.658228 · Cited by 31

Neural underpinnings of fine motor skills under stress and anxiety: A review

Martins, L. A., Schiavo, A., Paz, L. V., Xavier, L. L., & Mestriner, R. G. (2024) · Physiology & Behavior · doi:10.1016/j.physbeh.2024.114593 · Cited by 30

Neurotransmitters: an emerging target for therapeutic resistance to tumor immune checkpoint inhibitors

Yang, J., Wu, Y., Lv, X., Liu, S., Yuan, Z., Chen, Y., Ding, X., Zhong, L., & Wang, X. (2025) · Molecular Cancer · doi:10.1186/s12943-025-02413-8 · Cited by 30

Association study of dopamine receptor genes polymorphism with cognitive functions in bipolar I disorder patients

Zhao, L., Lin, Y., Lao, G., Wang, Y., Guan, L., Wei, J., Yang, Z., Ni, P., Li, X., Jiang, Z., et al. (2014) · Journal of Affective Disorders · doi:10.1016/j.jad.2014.08.039 · Cited by 30

Dazzled by the dominions of dopamine: clinical roles of D3, D2, and D1 receptors

Stahl, S. M. (2017) · CNS Spectrums · doi:10.1017/s1092852917000426 · Cited by 30

Association of genetic ancestry with striatal dopamine D2/D3 receptor availability

Wiers, C. E., Towb, P., Hodgkinson, C. A., Shen, P.-H., Freeman, C. R., Miller, G., Lindgren, E., Kojori, E. S., Demiral, Ş. B., Kim, S. W., et al. (2017) · Molecular Psychiatry · doi:10.1038/mp.2017.208 · Cited by 30

1-[3-(4-Butylpiperidin-1-yl)propyl]-1,2,3,4-tetrahydroquinolin-2-one (77-LH-28-1) as a Model for the Rational Design of a Novel Class of Brain Penetrant Ligands with High Affinity and Selectivity for Dopamine D4 Receptor

Bello, F. D., Bonifazi, A., Giorgioni, G., Cifani, C., Bonaventura, M. V. M. D., Petrelli, R., Piergentili, A., Fontana, S., Mammoli, V., Yano, H., et al. (2018) · Journal of Medicinal Chemistry · doi:10.1021/acs.jmedchem.8b00265 · Cited by 30

Selective D2 receptor PET in manganese-exposed workers

Criswell, S. R., Warden, M. N., Nielsen, S. S., Perlmutter, J. S., Moerlein, S. M., Sheppard, L. A., Lenox-Krug, J., Checkoway, H., & Racette, B. A. (2018) · Neurology · doi:10.1212/wnl.0000000000006163 · Cited by 30

Current and emerging pharmaceutical interventions for myopia

Vutipongsatorn, K., Yokoi, T., & Ohno‐Matsui, K. (2019) · British Journal of Ophthalmology · doi:10.1136/bjophthalmol-2018-313798 · Cited by 30

In vivo identification of small molecules mediating Gpr126/Adgrg6 signaling during Schwann cell development

Bradley, E. C., Cunningham, R. L., Wilde, C., Morgan, R. K., Klug, E. A., Letcher, S. M., Schöneberg, T., Monk, K. R., Liebscher, I., & Petersen, S. C. (2019) · Annals of the New York Academy of Sciences · doi:10.1111/nyas.14233 · Cited by 30

Chronic dietary exposure to arsenic at environmentally relevant concentrations impairs cognitive performance in adult zebrafish (Danio rerio) via oxidative stress and dopaminergic dysfunction

Rachamalla, M., Salahinejad, A., Khan, M., Datusalia, A. K., & Niyogi, S. (2023) · The Science of The Total Environment · doi:10.1016/j.scitotenv.2023.163771 · Cited by 30

The characterization, current medications, and promising therapeutics targets for premature ejaculation

Gür, S., & Sikka, S. C. (2015) · Andrology · doi:10.1111/andr.12032 · Cited by 30

Prion Protein Modulates Monoaminergic Systems and Depressive-like Behavior in Mice

Beckman, D., Santos, L. E., Americo, T. A., Ledo, J. H., Mello, F. G. D., & Linden, R. (2015) · Journal of Biological Chemistry · doi:10.1074/jbc.m115.666156 · Cited by 30

Modulation of A2a receptor antagonist on D2 receptor internalization and ERK phosphorylation

Huang, L., Wu, D., Zhang, L., & Feng, L. (2013) · Acta Pharmacologica Sinica · doi:10.1038/aps.2013.87 · Cited by 30

Expression and function of dopamine receptors in the developing medial frontal cortex and striatum of the rat

Daws, S. E., & Konradi, C. L. (2011) · Neuroscience · doi:10.1016/j.neuroscience.2011.10.004 · Cited by 30

Chronic cocaine disrupts mesocortical learning mechanisms

Buchta, W. C., & Riegel, A. C. (2015) · Brain Research · doi:10.1016/j.brainres.2015.02.003 · Cited by 30

Discovery, Optimization, and Characterization of Novel D2 Dopamine Receptor Selective Antagonists

Xiao, J., Free, R. B., Barnaeva, E. S., Conroy, J., Doyle, T. B., Miller, B. N., Bryant-Genevier, M. G., Taylor, M. K., Hu, X., Dulcey, A. E., et al. (2014) · Journal of Medicinal Chemistry · doi:10.1021/jm500126s · Cited by 30

Chronic Exposure to Arsenic in Drinking Water Causes Alterations in Locomotor Activity and Decreases Striatal mRNA for the D2 Dopamine Receptor in CD1 Male Mice

Ávila, C. L. M., Limón-Pacheco, J. H., Giòrdano, M., & Rodríguez, V. M. (2016) · Journal of Toxicology · doi:10.1155/2016/4763434 · Cited by 30

Multiple signaling pathways convey central and peripheral signals to regulate pituitary function: Lessons from human and non-human primate models

Vázquez-Borrego, M. C., Gahete, M. D., Martínez‐Fuentes, A. J., Fuentes-Fayos, A. C., Castano, J. P., Kineman, R. D., & Luque, R. M. (2017) · Molecular and Cellular Endocrinology · doi:10.1016/j.mce.2017.12.007 · Cited by 30

Radiobromine and radioiodine for medical applications

Wilbur, D. S., & Adam, M. J. (2019) · Radiochimica Acta · doi:10.1515/ract-2019-0004 · Cited by 30

Impaired dopamine- and adenosine-mediated signaling and plasticity in a novel rodent model for DYT25 dystonia

Yu-Taeger, L., Ott, T., Bonsi, P., Tomczak, C., Wassouf, Z., Martella, G., Sciamanna, G., Imbriani, P., Ponterio, G., Tassone, A., et al. (2019) · Neurobiology of Disease · doi:10.1016/j.nbd.2019.104634 · Cited by 30

Highly sensitive isotope-dilution liquid-chromatography–electrospray ionization–tandem-mass spectrometry approach to study the drug-mediated modulation of dopamine and serotonin levels in Caenorhabditis elegans

Schumacher, F., Chakraborty, S., Kleuser, B., Gulbins, E., Schwerdtle, T., Aschner, M., & Bornhorst, J. (2015) · Talanta · doi:10.1016/j.talanta.2015.05.057 · Cited by 30

Dissociable control of motivation and reinforcement by distinct ventral striatal dopamine receptors

Enríquez-Traba, J., Arenivar, M. A., Yarur, H. E., Noh, C., Flores, R. J., Weil, T. A., Roy, S., Usdin, T. B., LaGamma, C. T., Wang, H., et al. (2024) · Nature Neuroscience · doi:10.1038/s41593-024-01819-9 · Cited by 31

Impact of neuroinflammation on brain glutamate and dopamine signalling in schizophrenia: an update

Nayak, U. Y., Manikkath, J., Arora, D. S., & Mudgal, J. (2025) · Metabolic Brain Disease · doi:10.1007/s11011-025-01548-3 · Cited by 29

Neuronal circuits and physiological roles of the basal ganglia in terms of transmitters, receptors and related disorders

Yamada, K., TAKAHASHI, S. Y., Karube, F., Fujiyama, F., Kobayashi, K., Nishi, A., & Momiyama, T. (2016) · The Journal of Physiological Sciences · doi:10.1007/s12576-016-0445-4 · Cited by 29

Genetic deletion of the dopamine D3 receptor increases vulnerability to heroin in mice

Zhan, J., Jordan, C. J., Bi, G., He, X., Gardner, E. L., Wang, Y., & Xi, Z. (2018) · Neuropharmacology · doi:10.1016/j.neuropharm.2018.08.016 · Cited by 29

Dexmedetomidine Ameliorates Sleep Deprivation-Induced Depressive Behaviors in Mice

Moon, E.-J., Ko, I., Kim, S., Jin, J., Hwang, L., Kim, C., An, H., Lee, B.-J., & Yi, J.-W. (2018) · International Neurourology Journal · doi:10.5213/inj.1836228.114 · Cited by 29

Dopaminergic Agents in Rheumatoid Arthritis

Capellino, S. (2019) · Journal of Neuroimmune Pharmacology · doi:10.1007/s11481-019-09850-5 · Cited by 29

OATP1A2 and OATP2B1 Are Interacting with Dopamine-Receptor Agonists and Antagonists

Schäfer, A. M., zu Schwabedissen, H. E. M., Bien-Möller, S., Hubeny, A., Vogelgesang, S., Oswald, S., & Grube, M. (2020) · Molecular Pharmaceutics · doi:10.1021/acs.molpharmaceut.0c00159 · Cited by 29

Dopaminergic modulation of reward discounting in healthy rats: a systematic review and meta-analysis

Castrellon, J. J., Meade, J., Greenwald, L. M., Hurst, K., & Samanez-Larkin, G. R. (2020) · Psychopharmacology · doi:10.1007/s00213-020-05723-5 · Cited by 29

A rapid and sensitive method for the quantification of dopamine and serotonin metabolites in cerebrospinal fluid based on UHPLC with fluorescence detection

Boulghobra, A., Bonose, M., Billault, I., & Pallandre, A. (2022) · Journal of Chromatography B · doi:10.1016/j.jchromb.2022.123264 · Cited by 29

Whole-brain tracking of cocaine and sugar rewards processing

Bijoch, Ł., Klos, J., Pawłowska, M., Wiśniewska, J., Legutko, D., Szachowicz, U., Kaczmarek, L., & Beroun, A. (2023) · Translational Psychiatry · doi:10.1038/s41398-023-02318-4 · Cited by 29

Towards the convergent therapeutic potential of G protein‐coupled receptors in autism spectrum disorders

Annamneedi, A., Gora, C., Dudas, A., Leray, X., Bozon, V., Crépieux, P., & Pellissier, L. P. (2023) · British Journal of Pharmacology · doi:10.1111/bph.16216 · Cited by 29

The effect of modafinil on the rat dopamine transporter and dopamine receptors D1–D3 paralleling cognitive enhancement in the radial arm maze

Karabacak, Y., Sase, S., Aher, Y. D., Sase, A., Saroja, S. R., Cicvaric, A., Höger, H., Berger, M. L., Bakulev, V. A., Sitte, H. H., et al. (2015) · Frontiers in Behavioral Neuroscience · doi:10.3389/fnbeh.2015.00215 · Cited by 29

The Dopaminergic Reward System and Leisure Time Exercise Behavior: A Candidate Allele Study

Huppertz, C., Bartels, M., Groen‐Blokhuis, M. M., Dolan, C. V., de Moor, M. H. M., Abdellaoui, A., van Beijsterveldt, C. E. M., Ehli, E. A., Hottenga, J., Willemsen, G. A. H. M., et al. (2014) · BioMed Research International · doi:10.1155/2014/591717 · Cited by 29

Dopamine receptor dysregulation in hippocampus of aged rats underlies chronic pulsatile l-Dopa treatment induced cognitive and emotional alterations

Hernández, V. S., Luquı́n, S., Jáuregui-Huerta, F., Corona-Morales, A. A., Medina‐Pizarro, M., Ruiz‐Velasco, S., & Zhang, L. (2013) · Neuropharmacology · doi:10.1016/j.neuropharm.2013.11.013 · Cited by 29

Differential Role of D 1 and D 2 Receptors in the Perifornical Lateral Hypothalamus in Controlling Ethanol Drinking and Food Intake: Possible Interaction with Local Orexin Neurons

Chen, Y., Morganstern, I., Barson, J. R., Hoebel, B. G., & LEIBOWITZ, S. F. (2013) · Alcoholism Clinical and Experimental Research · doi:10.1111/acer.12313 · Cited by 29

Involvement of Dopamine D2 Receptors in Addictive-Like Behaviour for Acetaldehyde

Brancato, A., Plescia, F., Marino, R. A. M., Maniaci, G., Navarra, M., & Cannizzaro, C. (2014) · PLoS ONE · doi:10.1371/journal.pone.0099454 · Cited by 29

Effects of immobilization stress on emotional behaviors in dopamine D3 receptor knockout mice

Xing, B., Liu, P., Jiang, W., Liu, F., Zhang, H., Cao, G., Chen, T., & Dang, Y. (2013) · Behavioural Brain Research · doi:10.1016/j.bbr.2013.01.019 · Cited by 29

Synthesis and characterization of porous carbon–MoS 2 nanohybrid materials: electrocatalytic performance towards selected biomolecules

Dolinska, J., Chidambaram, A., Adamkiewicz, W., Estili, M., Lisowski, W., Iwan, M., Pałys, B., Sudhölter, E. J. R., Marken, F., Opałło, M., et al. (2016) · Journal of Materials Chemistry B · doi:10.1039/c5tb02175h · Cited by 29

A novel report of MiR‐4301 induces cell apoptosis by negatively regulating DRD2 expression in human breast cancer cells

Gholipour, N., Ohradanova‐Repic, A., & Ahangari, G. (2017) · Journal of Cellular Biochemistry · doi:10.1002/jcb.26577 · Cited by 29

Etiology and functional validation of gastrointestinal motility dysfunction in a zebrafish model of CHARGE syndrome

Cloney, K., Steele, S. L., Stoyek, M. R., Croll, R. P., Smith, F. M., Prykhozhij, S. V., Brown, M. M., Midgen, C., BLAKE, K. D., & Berman, J. N. (2018) · FEBS Journal · doi:10.1111/febs.14473 · Cited by 29

Chemoenzymatic synthesis and evaluation of 3-azabicyclo[3.2.0]heptane derivatives as dopaminergic ligands

Reinart‐Okugbeni, R., Ausmees, K., Kriis, K., Werner, F. F., Rinken, A., & Kanger, T. (2012) · European Journal of Medicinal Chemistry · doi:10.1016/j.ejmech.2012.07.025 · Cited by 29

Dopamine Signaling in Circadian Photoentrainment: Consequences of Desynchrony.

Grippo, R. M., & Güler, A. D. (2019) · PubMed Central · Cited by 29

Variability in Action Selection Relates to Striatal Dopamine 2/3 Receptor Availability in Humans: A PET Neuroimaging Study Using Reinforcement Learning and Active Inference Models

Adams, R. A., Moutoussis, M., Nour, M. M., Dahoun, T., Lewis, D. J., Illingworth, B. J. G., Veronese, M., Mathys, C. D., de Boer, L., Guitart‐Masip, M., et al. (2019) · Cerebral Cortex · doi:10.1093/cercor/bhz327 · Cited by 29

Lipid Rafts and Dopamine Receptor Signaling

Martinez, V. J., Asico, L. D., José, P. A., & Tiu, A. C. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21238909 · Cited by 29

Heteromerization of dopaminergic receptors in the brain: Pharmacological implications

Misganaw, D. (2021) · Pharmacological Research · doi:10.1016/j.phrs.2021.105600 · Cited by 29

Nonhuman Primate Models of Addiction and PET Imaging: Dopamine System Dysregulation

Gould, R. W., Porrino, L. J., & Nader, M. A. (2011) · Current topics in behavioral neurosciences · doi:10.1007/7854_2011_168 · Cited by 29

Clinical Motor and Cognitive Neurobehavioral Relationships in the Basal Ganglia

Leisman, G., Melillo, R. J., & Frederick, R. (2013) · InTech eBooks · doi:10.5772/55227 · Cited by 29

Early-Life Adversity Induces Epigenetically Regulated Changes in Hippocampal Dopaminergic Molecular Pathways

Köhler, J. C., Gröger, N., Lesse, A., Guara Ciurana, S., Rether, K., Fegert, J., Bock, J., & Braun, K. (2019) · Molecular Neurobiology · doi:10.1007/s12035-018-1199-1 · Cited by 28

Impact of micronutrients and nutraceuticals on cognitive function and performance in Alzheimer's disease

Guarnieri, L., Bosco, F., Leo, A., Citraro, R., Palma, E., Sarro, G. D., & Mollace, V. (2024) · Ageing Research Reviews · doi:10.1016/j.arr.2024.102210 · Cited by 28

Tonic Dopamine Induces Persistent Changes in the Transient Potassium Current through Translational Regulation

Rodgers, E. W., Krenz, W. C., & Baro, D. J. (2011) · Journal of Neuroscience · doi:10.1523/jneurosci.2194-11.2011 · Cited by 28

Models of neuromodulation for computational psychiatry

Iglesias, S., Tomiello, S., Schneebeli, M., & Stephan, K. E. (2016) · Wiley Interdisciplinary Reviews Cognitive Science · doi:10.1002/wcs.1420 · Cited by 28

Pt-grown carbon nanofibers for enzymatic glutamate biosensors and assessment of their biocompatibility

Isoaho, N., Peltola, E., Sainio, S., Koskinen, J., & Laurila, T. T. (2018) · RSC Advances · doi:10.1039/c8ra07766e · Cited by 28

Influence of bradykinin B2 receptor and dopamine D2 receptor on the oxidative stress, inflammatory response, and apoptotic process in human endothelial cells

Niewiarowska-Sendo, A., Kozik, A., & Guevara-Lora, I. (2018) · PLoS ONE · doi:10.1371/journal.pone.0206443 · Cited by 28

Defining Structure–Functional Selectivity Relationships (SFSR) for a Class of Non-Catechol Dopamine D1 Receptor Agonists

Martini, M. L., Liu, J., Ray, C., Yu, X., Huang, X., Urs, A. N., Urs, N. M., McCorvy, J. D., Caron, M. G., Roth, B. L., et al. (2019) · Journal of Medicinal Chemistry · doi:10.1021/acs.jmedchem.9b00351 · Cited by 28

Altered gastric tone and motility response to brain-stem dopamine in a rat model of parkinsonism

Bove, C., Anselmi, L., & Travagli, R. A. (2019) · American Journal of Physiology-Gastrointestinal and Liver Physiology · doi:10.1152/ajpgi.00076.2019 · Cited by 28

Brain targeted delivery of lurasidone HCl via nasal administration of mucoadhesive nanoemulsion formulation for the potential management of schizophrenia

Patel, M. R., Patel, R. B., Thakore, S. D., & Solanki, A. B. (2020) · Pharmaceutical Development and Technology · doi:10.1080/10837450.2020.1772292 · Cited by 28

Anxiety-like behavior in female mice is modulated by STAT3 signaling in midbrain dopamine neurons

Fernandes, M. F., Lau, D., Sharma, S., & Fulton, S. (2021) · Brain Behavior and Immunity · doi:10.1016/j.bbi.2021.04.013 · Cited by 28

Cannabinoid Modulation of Dopamine Release During Motivation, Periodic Reinforcement, Exploratory Behavior, Habit Formation, and Attention

Oleson, E. B., Hamilton, L. R., & Gomez, D. M. (2021) · Frontiers in Synaptic Neuroscience · doi:10.3389/fnsyn.2021.660218 · Cited by 28

Lipopolysaccharide/D-galactosamine-induced acute liver injury could be attenuated by dopamine receptor agonist rotigotine via regulating NF-κB signaling pathway

Yue, S., Wang, T., Yang, Y., Fan, Y., Zhou, L., Li, M., & Fu, F. (2021) · International Immunopharmacology · doi:10.1016/j.intimp.2021.107798 · Cited by 28

Cannabidiol impairs the rewarding effects of methamphetamine: Involvement of dopaminergic receptors in the nucleus accumbens

Sharifi, A., Karimi‐Haghighi, S., Shabani, R., Asgari, H. R., Ahadi, R., & Haghparast, A. (2021) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2021.110458 · Cited by 28

Resistance to Dopamine Agonists in Pituitary Tumors: Molecular Mechanisms

Pivonello, C., Patalano, R., Negri, M., Pirchio, R., Colao, A. A. L., Pivonello, R., & Auriemma, R. S. (2022) · Frontiers in Endocrinology · doi:10.3389/fendo.2021.791633 · Cited by 28

Neurocognitive Psychiatric and Neuropsychological Alterations in Parkinson’s Disease: A Basic and Clinical Approach

González-Usigli, H., Ortíz, G. G., Niño, C. L. C., Mireles-Ramírez, M. A., Pacheco-Moisés, F. P., Torres-Mendoza, B. M., Hernández-Cruz, J. J., Delgado-Lara, D. L. C., & Ramírez-Jirano, L. J. (2023) · Brain Sciences · doi:10.3390/brainsci13030508 · Cited by 28

Effects of hypothyroidism on the respiratory system and control of breathing: Human studies and animal models

Schlenker, E. H. (2012) · Respiratory Physiology & Neurobiology · doi:10.1016/j.resp.2012.02.007 · Cited by 28

Early antipsychotic treatment in childhood/adolescent period has long-term effects on depressive-like, anxiety-like and locomotor behaviours in adult rats

Santis, M. D., Lian, J., Huang, X., & Deng, C. (2015) · Journal of Psychopharmacology · doi:10.1177/0269881115616383 · Cited by 28

Activation of Dopamine D1 Receptors in Dermal Fibroblasts Restores Vascular Endothelial Growth Factor-A Production by These Cells and Subsequent Angiogenesis in Diabetic Cutaneous Wound Tissues

Chakroborty, D., Sarkar, C., Lǚ, K., Bhat, M., Dasgupta, P., & Basu, S. (2016) · American Journal Of Pathology · doi:10.1016/j.ajpath.2016.05.008 · Cited by 28

The potential roles of dopamine in malignant glioma

Lan, Y., Wang, X., Xing, J., Lou, J., Ma, X., & Zhang, B. (2016) · Acta Neurologica Belgica · doi:10.1007/s13760-016-0730-2 · Cited by 28

Emerging role of dopamine in neovascularization of pheochromocytoma and paraganglioma

Osinga, T. E., Links, T. P., Dullaart, R. P. F., Pacák, K., van der Horst‐Schrivers, A. N. A., Kerstens, M. N., & Kema, I. P. (2017) · The FASEB Journal · doi:10.1096/fj.201601131r · Cited by 28

Dopamine D2 receptors and the circadian clock reciprocally mediate antipsychotic drug-induced metabolic disturbances

Freyberg, Z., & McCarthy, M. J. (2017) · Schizophrenia · doi:10.1038/s41537-017-0018-4 · Cited by 28

Ventral tegmental area D2 receptor knockdown enhances choice impulsivity in a delay-discounting task in rats

Bernosky‐Smith, K. A., Qiu, Y., Feja, M., Lee, Y. B., Loughlin, B., Li, J., & Bass, C. E. (2017) · Behavioural Brain Research · doi:10.1016/j.bbr.2017.12.029 · Cited by 28

In Silico Studies Targeting G-protein Coupled Receptors for Drug Research Against Parkinson’s Disease

Lemos, A., Melo, R., Preto, A. J., de Almeida, J. G., Moreira, I. S., & Cordeiro, M. N. D. S. (2018) · Current Neuropharmacology · doi:10.2174/1570159x16666180308161642 · Cited by 28

Deconstructing value-based decision making via temporally selective manipulation of neural activity: Insights from rodent models

Orsini, C. A., Hernandez, C. M., Bizon, J. L., & Setlow, B. (2018) · Cognitive Affective & Behavioral Neuroscience · doi:10.3758/s13415-018-00649-0 · Cited by 28

The small molecule CA140 inhibits the neuroinflammatory response in wild-type mice and a mouse model of AD

Lee, J., Nam, J. H., Nam, Y., Nam, H. Y., Yoon, G., Ko, E., Kim, G.-C., Bautista, M. R., Capule, C. C., Koyanagi, T., et al. (2018) · Journal of Neuroinflammation · doi:10.1186/s12974-018-1321-3 · Cited by 28

Primate Nigrostriatal Dopamine System Regulates Saccadic Response Inhibition

Ogasawara, T., Nejime, M., Takada, M., & Matsumoto, M. (2018) · Neuron · doi:10.1016/j.neuron.2018.10.025 · Cited by 28

Conventional and Novel Pharmacological Approaches to Treat Dopamine-Related Disorders: Focus on Parkinson’s Disease and Schizophrenia

de la Mora, M. P., Hernández-Mondragón, J. C., Crespo‐Ramírez, M., Rejón-Orantes, J. D. C., Borroto‐Escuela, D. O., & Fuxé, K. (2019) · Neuroscience · doi:10.1016/j.neuroscience.2019.07.026 · Cited by 28

Anti‐dopamine D2 receptor antibodies in chronic tic disorders

Addabbo, F., Baglioni, V., Schrag, A. E., Schwarz, M. J., Dietrich, A., Hoekstra, P. J., Martino, D., Buttiglione, M., & Emtics Collaborative Group (2020) · Developmental Medicine & Child Neurology · doi:10.1111/dmcn.14613 · Cited by 29

Influence of dopamine receptor gene polymorphisms on circulating T lymphocytes: A pilot study in healthy subjects

Cosentino, M., Ferrari, M., Kuštrimović, N. Z., Rasini, E., & Marino, F. (2015) · Human Immunology · doi:10.1016/j.humimm.2015.09.032 · Cited by 28

L-745,870 reduces the expression of abnormal involuntary movements in the 6-OHDA-lesioned rat

Huot, P., Johnston, T. H., Koprich, J. B., Espinosa, M. C., Reyes, M. G., Fox, S. H., & Brotchie, J. M. (2014) · Behavioural Pharmacology · doi:10.1097/fbp.0000000000000096 · Cited by 28

Dysregulation of the dopaminergic system secondary to traumatic brain injury: implications for mood and anxiety disorders

Mata-Bermúdez, A., Trejo-Chávez, R., Martínez-Vargas, M., Pérez-Arredondo, A., Martínez-Cárdenas, M. D. L. Á., Dı́az-Ruiz, A., Rı́os, C., & Navarro, L. (2024) · Frontiers in Neuroscience · doi:10.3389/fnins.2024.1447688 · Cited by 27

Identification of a new selective dopamine D4 receptor ligand

Sampson, D., Zhu, X. Y., Eyunni, S., Etukala, J. R., Ofori, E., Bricker, B. A., Lamango, N. S., Setola, V., Roth, B. L., & Ablordeppey, S. Y. (2014) · Bioorganic & Medicinal Chemistry · doi:10.1016/j.bmc.2014.04.026 · Cited by 27

Chronic administration of aripiprazole activates GSK3β-dependent signalling pathways and up-regulates GABAA receptor expression and CREB1 activity in rats

Pan, B., Huang, X., & Deng, C. (2016) · Scientific Reports · doi:10.1038/srep30040 · Cited by 27

DAKB-GPCRs: An Integrated Computational Platform for Drug Abuse Related GPCRs

Chen, M., Jing, Y., Wang, L., Feng, Z., & Xie, X. (2019) · Journal of Chemical Information and Modeling · doi:10.1021/acs.jcim.8b00623 · Cited by 27

Current Knowledge on the Multifactorial Regulation of Corpora Lutea Lifespan: The Rabbit Model

Zerani, M., Polisca, A., Boiti, C., & Maranesi, M. (2021) · Animals · doi:10.3390/ani11020296 · Cited by 27

Canonical and Non-Canonical Antipsychotics’ Dopamine-Related Mechanisms of Present and Next Generation Molecules: A Systematic Review on Translational Highlights for Treatment Response and Treatment-Resistant Schizophrenia

de Bartolomeis, A., Ciccarelli, M., Simone, G. D., Mazza, B., Barone, A., & Vellucci, L. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms24065945 · Cited by 29

Single hormone or synthetic agonist induces G s /G i coupling selectivity of EP receptors via distinct binding modes and propagating paths

Huang, S.-M., Xiong, M.-Y., Liu, L., Mu, J., Wang, M.-W., Jia, Y., Cai, K., Tie, L., Zhang, C., Cao, S., et al. (2023) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2216329120 · Cited by 27

Dopamine D4 receptors inhibit proliferation and migration of vascular smooth muscle cells induced by insulin via down-regulation of insulin receptor expression

Yu, C., Wang, Z., Han, Y., Liu, Y., Wang, W. E., Chen, C., Wang, H., José, P. A., & Zeng, C. (2014) · Cardiovascular Diabetology · doi:10.1186/1475-2840-13-97 · Cited by 27

Inhibiting effects of rhynchophylline on zebrafish methamphetamine dependence are associated with amelioration of neurotransmitters content and down-regulation of TH and NR2B expression

Jiang, M., Chen, Y., Li, C., Peng, Q., Fang, M., Liu, W., Qun-zhao, K., Lin, Y., Yung, K. K. L., & Mo, Z. (2016) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2016.03.004 · Cited by 27

Association of DRD3 , COMT , and SLC6A4 Gene Polymorphisms with Type 2 Diabetes in Southern Chinese: A Hospital-Based Case–Control Study

Xiu, L., Lin, M., Liu, W., Kong, D., Liu, Z., Zhang, Y., Ouyang, P., Liang, Y., Zhong, S., Chen, C., et al. (2015) · Diabetes Technology & Therapeutics · doi:10.1089/dia.2014.0344 · Cited by 27

Neuronal signaling repertoire in the mammalian sperm functionality

Ramírez‐Reveco, A., Villarroel‐Espíndola, F., Rodríguez-Gil, J. E., & Concha, I. I. (2017) · Biology of Reproduction · doi:10.1095/biolreprod.116.144154 · Cited by 27

Molecular and synaptic mechanisms regulating drug-associated memories: towards a bidirectional treatment strategy

Rich, M. T., & Torregrossa, M. M. (2018) · Brain Research Bulletin · doi:10.1016/j.brainresbull.2017.09.003 · Cited by 27

Dopamine receptors – IUPHAR R eview 13

Beaulieu, J., Espinoza, S., & Gainetdinov, R. R. (2014) · British Journal of Pharmacology · doi:10.1111/bph.12906 · Cited by 561

Structure and function of dopamine receptors

Vallone, D., Picetti, R., & Borrelli, E. (2000) · Neuroscience & Biobehavioral Reviews · doi:10.1016/s0149-7634(99)00063-9 · Cited by 857

[Dopamine receptors--structure, characterization and function].

Zawilska, J. B. (2003) · PubMed · Cited by 8

The dopamine D4 receptor: one decade of research

Oak, J. N., Oldenhof, J., & Tol, H. H. M. V. (2000) · European Journal of Pharmacology · doi:10.1016/s0014-2999(00)00562-8 · Cited by 421

Dopamine: Functions, Signaling, and Association with Neurological Diseases

Klein, M. O., Battagello, D. S., Cardoso, A. R., Hauser, D. N., Bittencourt, J. C., & Correa, R. G. (2019) · Cellular and Molecular Neurobiology · doi:10.1007/s10571-018-0632-3 · Cited by 1,073