The DOI matches its Crossref record; 37 of the 37 references it cites were found in a registry or an index.
A CRISPR-Cas autocatalysis-driven feedback amplification network for supersensitive DNA diagnostics
Open accessAbstract
A CRISPR-Cas–driven positive feedback circuit with exponential dynamic enables ultrasensitive detection of genomic DNA.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
CRISPR-Cas12a target binding unleashes indiscriminate single-stranded DNase activity
Chen, J. S., Ma, E., Harrington, L. B., Da Costa, M., Tian, X., Palefsky, J. M., & Doudna, J. A. (2018) · Science · doi:10.1126/science.aar6245 · Cited by 4,507
Nucleic acid detection with CRISPR-Cas13a/C2c2
Gootenberg, J. S., Abudayyeh, O. O., Lee, J. W., Essletzbichler, P., Dy, A. J., Joung, J., Verdine, V., Donghia, N., Daringer, N. M., Freije, C. A., et al. (2017) · Science · doi:10.1126/science.aam9321 · Cited by 3,844
Multiplexed and portable nucleic acid detection platform with Cas13, Cas12a, and Csm6
Gootenberg, J. S., Abudayyeh, O. O., Kellner, M. J., Joung, J., Collins, J. J., & Zhang, F. (2018) · Science · doi:10.1126/science.aaq0179 · Cited by 2,638
An updated evolutionary classification of CRISPR–Cas systems
Makarova, K. S., Wolf, Y. I., Alkhnbashi, O. S., Costa, F., Shah, S. A., Saunders, S. J., Barrangou, R., Brouns, S. J. J., Charpentier, E., Haft, D. H., et al. (2015) · Nature Reviews Microbiology · doi:10.1038/nrmicro3569 · Cited by 2,480
Triggered amplification by hybridization chain reaction
Dirks, R. M., & Pierce, N. A. (2004) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0407024101 · Cited by 2,063
Programming biomolecular self-assembly pathways
Yin, P., Choi, H. M. T., Calvert, C. R., & Pierce, N. A. (2008) · Nature · doi:10.1038/nature06451 · Cited by 1,600
CRISPR-Cas12a-assisted nucleic acid detection
Li, S.-Y., Cheng, Q.-X., Wang, J.-M., Li, X.-Y., Zhang, Z.-L., Gao, S., Cao, R.-B., Zhao, G.-P., & Wang, J. (2018) · Cell Discovery · doi:10.1038/s41421-018-0028-z · Cited by 1,530
CRISPR-Cas guides the future of genetic engineering
Knott, G. J., & Doudna, J. A. (2018) · Science · doi:10.1126/science.aat5011 · Cited by 1,410
Programmed DNA destruction by miniature CRISPR-Cas14 enzymes
Harrington, L. B., Burstein, D., Chen, J. S., Paez-Espino, D., Ma, E., Witte, I. P., Cofsky, J. C., Kyrpides, N. C., Banfield, J. F., & Doudna, J. A. (2018) · Science · doi:10.1126/science.aav4294 · Cited by 1,247
Engineering Entropy-Driven Reactions and Networks Catalyzed by DNA
Zhang, D. Y., Turberfield, A. J., Yurke, B., & Winfree, E. (2007) · Science · doi:10.1126/science.1148532 · Cited by 1,242
Two distinct RNase activities of CRISPR-C2c2 enable guide-RNA processing and RNA detection
East-Seletsky, A., O’Connell, M. R., Knight, S. C., Burstein, D., Cate, J. H. D., Tjian, R., & Doudna, J. A. (2016) · Nature · doi:10.1038/nature19802 · Cited by 1,236
Tiollais, P., Pourcel, C., & Dejean, A. (1985) · Nature · doi:10.1038/317489a0 · Cited by 1,205
DINAMelt web server for nucleic acid melting prediction
Markham, N. R., & Zuker, M. (2005) · Nucleic Acids Research · doi:10.1093/nar/gki591 · Cited by 944
Li, L., Li, S., Wu, N., Wu, J., Wang, G., Zhao, G., & Wang, J. (2019) · ACS Synthetic Biology · doi:10.1021/acssynbio.9b00209 · Cited by 793
Wang, F., Lu, C.-H., & Willner, I. (2014) · Chemical Reviews · doi:10.1021/cr400354z · Cited by 649
Structural Basis for Guide RNA Processing and Seed-Dependent DNA Targeting by CRISPR-Cas12a
Swarts, D. C., van der Oost, J., & Jinek, M. (2017) · Molecular Cell · doi:10.1016/j.molcel.2017.03.016 · Cited by 608
Mechanistic Insights into the cis- and trans-Acting DNase Activities of Cas12a
Swarts, D. C., & Jinek, M. (2019) · Molecular Cell · doi:10.1016/j.molcel.2018.11.021 · Cited by 592
Zuo, X., Xia, F., Xiao, Y., & Plaxco, K. W. (2010) · Journal of the American Chemical Society · doi:10.1021/ja909551b · Cited by 497
The crystal structure of Cpf1 in complex with CRISPR RNA
Dong, D., Ren, K., Qiu, X., Zheng, J., Guo, M., Guan, X., Liu, H., Li, N., Zhang, B., Yang, D., et al. (2016) · Nature · doi:10.1038/nature17944 · Cited by 430
Self-citationHuman cancers express mutator phenotypes: origin, consequences and targeting
Loeb, L. A. (2011) · Nature Reviews Cancer · doi:10.1038/nrc3063 · Cited by 396
Teng, F., Guo, L., Cui, T., Wang, X.-G., Xu, K., Gao, Q., Zhou, Q., & Li, W. (2019) · Genome Biology · doi:10.1186/s13059-019-1742-z · Cited by 385
Li, J., Green, A. A., Yan, H., & Fan, C. (2017) · Nature Chemistry · doi:10.1038/nchem.2852 · Cited by 353
Henderson, S., Chakravarthy, A., Su, X., Boshoff, C., & Fenton, T. R. (2014) · Cell Reports · doi:10.1016/j.celrep.2014.05.012 · Cited by 345
López-Knowles, E., Hernández, S., Malats, N., Kogevinas, M., Lloreta, J., Carrato, A., Tardón, A., Serra, C., Real, F. X., & EPICURO Study Group Investigators (2006) · Cancer Research · doi:10.1158/0008-5472.can-06-1182 · Cited by 218
Lopez-Knowles, E., Hernandez, S., Malats, N., Kogevinas, M., Lloreta, J., Carrato, A., Tardon, A., Serra, C., & Real, F. X. (2006) · European Urology Supplements · doi:10.1016/s1569-9056(06)61338-9 · Cited by 173
A DNAzyme Feedback Amplification Strategy for Biosensing
Liu, M., Zhang, Q., Chang, D., Gu, J., Brennan, J. D., & Li, Y. (2017) · Angewandte Chemie International Edition · doi:10.1002/anie.201700054 · Cited by 161
Anti-CRISPR-mediated control of gene editing and synthetic circuits in eukaryotic cells
Nakamura, M., Srinivasan, P., Chavez, M., Carter, M., Dominguez, A. A., Russa, M. F. L., Lau, M. B., Abbott, T. R., Xu, X., Zhao, D., et al. (2019) · Nature Communications · doi:10.1038/s41467-018-08158-x · Cited by 147
Switching the activity of Cas12a using guide RNA strand displacement circuits
Oesinghaus, L., & Simmel, F. C. (2019) · Nature Communications · doi:10.1038/s41467-019-09953-w · Cited by 142
Engineering Synthetic Gene Circuits in Living Cells with CRISPR Technology
Jusiak, B., Cleto, S., Pérez‐Piñera, P., & Lu, T. K. (2016) · Trends in biotechnology · doi:10.1016/j.tibtech.2015.12.014 · Cited by 133
Isothermal digital detection of microRNAs using background-free molecular circuit
Gines, G., Menezes, R., Nara, K., Kirstetter, A.-S., Taly, V., & Rondelez, Y. (2020) · Science Advances · doi:10.1126/sciadv.aay5952 · Cited by 119
Luo, X., Xue, B., Feng, G., Zhang, J., Lin, B., Zeng, P., Li, H., Yi, H., Zhang, X., Zhu, H., et al. (2019) · Journal of the American Chemical Society · doi:10.1021/jacs.8b10265 · Cited by 116
Self-citationHanewich-Hollatz, M. H., Chen, Z., Hochrein, L. M., Huang, J., & Pierce, N. A. (2019) · ACS Central Science · doi:10.1021/acscentsci.9b00340 · Cited by 111
Constrained Multistate Sequence Design for Nucleic Acid Reaction Pathway Engineering
Wolfe, B. R., Porubsky, N. J., Zadeh, J. N., Dirks, R. M., & Pierce, N. A. (2017) · Journal of the American Chemical Society · doi:10.1021/jacs.6b12693 · Cited by 106
Multiple Input Sensing and Signal Integration Using a Split Cas12a System
Kempton, H. R., Goudy, L., Love, K. S., & Qi, L. S. (2020) · Molecular Cell · doi:10.1016/j.molcel.2020.01.016 · Cited by 94
A modular positive feedback-based gene amplifier
Nistala, G. J., Wu, K., Rao, C. V., & Bhalerao, K. D. (2010) · Journal of Biological Engineering · doi:10.1186/1754-1611-4-4 · Cited by 69
Detection of HBV Covalently Closed Circular DNA
Li, X., Zhao, J., Yuan, Q., & Xia, N. (2017) · Viruses · doi:10.3390/v9060139 · Cited by 60
A DNAzyme-powered cross-catalytic circuit for amplified intracellular imaging
Zou, L., Wu, Q. D., Zhou, Y., Gong, X. Q., Liu, X., & Wang, F. (2019) · Chemical Communications · doi:10.1039/c9cc02637a · Cited by 60
Cited by
Amplification-free CRISPR/Cas detection technology: challenges, strategies, and perspectives
Li, H., Xie, Y., Chen, F., Bai, H., Xiu, L., Zhou, X., Guo, X., Hu, Q., & Yin, K. (2023) · Chemical Society Reviews · doi:10.1039/d2cs00594h · Cited by 346
Programmable RNA detection with CRISPR-Cas12a
Rananaware, S. R., Vesco, E. K., Shoemaker, G. M., Anekar, S. S., Sandoval, L. S. W., Meister, K. S., Macaluso, N. C., Nguyen, L. T., & Jain, P. K. (2023) · Nature Communications · doi:10.1038/s41467-023-41006-1 · Cited by 266
Metadata
- Authors
- Shi, K., Xie, S., Tian, R., Wang, S., Lu, Q., Gao, D., Lei, C., Zhu, H., & Nie, Z.
- Venue
- Science Advances
- Published
- 2021-01-29
- Volume
- 7
- Issue
- 5
- ISSN
- 2375-2548 (ISSN-L)
- OpenAlex
- W3123905071
- Cited by
- 334
- References
- 37
- FWCI
- 13.28
- Type
- journal article
- Language
- en
- Open access
- gold
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.