The DOI matches its Crossref record; 24 of the 24 references it cites were found in a registry or an index.
Autoimmune Disease and Impaired Uptake of Apoptotic Cells in MFG-E8-Deficient Mice
Abstract
Apoptotic cells expose phosphatidylserine and are swiftly engulfed by macrophages. Milk fat globule epidermal growth factor (EGF) factor 8 (MFG-E8) is a protein that binds to apoptotic cells by recognizing phosphatidylserine and that enhances the engulfment of apoptotic cells by macrophages. We report that tingible body macrophages in the germinal centers of the spleen and lymph nodes strongly express MFG-E8. Many apoptotic lymphocytes were found on the MFG-E8 –/– tingible body macrophages, but they were not efficiently engulfed. The MFG-E8 –/– mice developed splenomegaly, with the formation of numerous germinal centers, and suffered from glomerulonephritis as a result of autoantibody production. These data demonstrate that MFG-E8 has a critical role in removing apoptotic B cells in the germinal centers and that its failure can lead to autoimmune diseases.
Overview
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“The best characterized of these are the soluble protein MFG-E8 87,121 and the glycolipid-anchored protein Tim-4 88.”
From Immunogenic and tolerogenic cell death (2009) · cites this paper as [88]
Citations
Cites
Fadok, V. A., Voelker, D. R., Campbell, P. A., Cohen, J., Bratton, D. L., & Henson, P. M. (1992) · The Journal of Immunology · doi:10.4049/jimmunol.148.7.2207 · Cited by 3,321
Programmed Cell Death in Animal Development
Jacobson, M. D., Weil, M., & RAFF, M. C. (1997) · Cell · doi:10.1016/s0092-8674(00)81873-5 · Cited by 2,685
A blast from the past: clearance of apoptotic cells regulates immune responses
Savill, J., Dransfield, I., Gregory, C. D., & Haslett, C. (2002) · Nature reviews. Immunology · doi:10.1038/nri957 · Cited by 1,574
Corpse clearance defines the meaning of cell death
Savill, J., & Fadok, V. A. (2000) · Nature · doi:10.1038/35037722 · Cited by 1,572
Identification of a factor that links apoptotic cells to phagocytes
Hanayama, R., Tanaka, M., Miwa, K., Shinohara, A., Iwamatsu, A., & Nagata, S. (2002) · Nature · doi:10.1038/417182a · Cited by 1,401
Self-citationPhagocytosis and clearance of apoptotic cells is mediated by MER
Scott, R. S., McMahon, E. J., Pop, S. M., Reap, E. A., Caricchio, R., Cohen, P. L., Earp, H. S., & Matsushima, G. K. (2001) · Nature · doi:10.1038/35075603 · Cited by 1,215
T-cell apoptosis detected in situ during positive and negative selection in the thymus
Surh, C. D., & Sprent, J. (1994) · Nature · doi:10.1038/372100a0 · Cited by 1,082
Systemic Exposure to Irradiated Apoptotic Cells Induces Autoantibody Production
Mevorach, D., Zhou, J. L., Song, X., & Elkon, K. B. (1998) · The Journal of Experimental Medicine · doi:10.1084/jem.188.2.387 · Cited by 567
Hoffmann, P. R., deCathelineau, A. M., Ogden, C. A., Leverrier, Y., Bratton, D. L., Daleke, D. L., Ridley, A. J., Fadok, V. A., & Henson, P. M. (2001) · The Journal of Cell Biology · doi:10.1083/jcb.200108080 · Cited by 541
Stubbs, J. D., Lekutis, C., Singer, K. L., Bui, A., Yuzuki, D., Srinivasan, U., & Parry, G. (1990) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.87.21.8417 · Cited by 313
Flagged first, then by citations
Research works printed but not linked: 3
- G. Kraal, M. Janse, Immunology58, 665 (1986).
- V. J. Gauthier, C. K. Abrass, Semin. Nephrol.12, 379 (1992).
- G. Kelsoe, Immunity4, 107 (1996).
Cited by
Sorted by citations
Items 801–900 of 991
Wang, J., Hashimoto, Y., Hiemori-Kondo, M., Nakamoto, A., Sakai, T., Ye, W., & Abe‐Kanoh, N. (2024) · Bioscience Biotechnology and Biochemistry · doi:10.1093/bbb/zbae079 · Cited by 3
Consequence of alcohol intoxication-mediated efferocytosis impairment
Brahadeeswaran, S., & Tamizhselvi, R. (2024) · Frontiers in Immunology · doi:10.3389/fimmu.2024.1386658 · Cited by 4
Homeostatic Functions of Tissue-Resident Macrophages and Their Role in Tissue Maintenance
Crisóstomo, L., Mäkinen, A., Hyseni, B., Bergman, H. ‐., & Mildner, A. (2024) · Results and problems in cell differentiation · doi:10.1007/978-3-031-65944-7_1 · Cited by 3
Saas, P., Bonnefoy, F., Kleinclauss, F., Sun, Y., Tiberghien, P., Gaugler, B., & Perruche, S. (2008) · Transfusion Clinique et Biologique · doi:10.1016/j.tracli.2008.04.004 · Cited by 3
Iizuka, A., Segawa, S., Kondo, Y., Kaneko, S., Yokosawa, M., Furuyama, K., Miki, H., Tahara‐Hanaoka, S., Shibuya, A., Tsuboi, H., et al. (2018) · International Journal of Rheumatic Diseases · doi:10.1111/1756-185x.13381 · Cited by 3
Spleen, lymph nodes, and lymphoid tissues—Inflammatory system
Lima-Junior, D. S., Collins, N., & Han, S. (2022) · Elsevier eBooks · doi:10.1016/b978-0-12-821385-8.00001-9 · Cited by 3
Luo, Y., Lu, D., Zhou, J., Wu, J., Wang, W., & Qian, L. (2023) · Stem Cells and Development · doi:10.1089/scd.2022.0247 · Cited by 3
Nie, K., Liu, S., Zhang, L., Zhang, Z., Xiao, Z., & Ji, Y. (2017) · Oncology and Translational Medicine · doi:10.1007/s10330-016-0184-4 · Cited by 3
Host DNA Induced Inflammation and Autoimmune Diseases
Pandey, S., & Kawai, T. (2013) · Elsevier eBooks · doi:10.1016/b978-0-12-404732-7.00005-8 · Cited by 3
Two paradoxes and a surprise on the road to an understanding of systemic lupus erythematosus
Salaman, M. R. (2012) · Immunology Letters · doi:10.1016/j.imlet.2012.07.004 · Cited by 3
Kajiwara, C., Kimura, S., Tanaka, Y., Akasaka, Y., Ishii, Y., & Tateda, K. (2020) · ImmunoHorizons · doi:10.4049/immunohorizons.2000054 · Cited by 3
Milk fat-globule epidermal growth factor 8: A potential Regulator of Cutaneous Wound Healing
Xiao, Y., Tang, Y., Shu, X., Zhu, J., Wu, X., & Zhang, Y. (2022) · Molecular Biology Reports · doi:10.1007/s11033-022-07365-6 · Cited by 3
Proteases from Inflammatory Cells: Regulation of Inflammatory Response
Pederzoli-Ribeil, M., Gabillet, J., & Witko‐Sarsat, V. (2011) · Springer eBooks · doi:10.1007/978-3-0348-0157-7_4 · Cited by 3
Acute kidney injury: Clear the kidney of apoptotic debris!*
Harrois, A., & Duranteau, J. (2011) · Critical Care Medicine · doi:10.1097/ccm.0b013e318226619c · Cited by 3
Loss-of-function of MFGE8 and protection against coronary atherosclerosisPreprint
Ruotsalainen, S., Surakka, I. L., Mars, N., Karjalainen, J. M., Kurki, M., Kanai, M., Krebs, K., Mishra, P. P., Mishra, B. H., Sinisalo, J. P., et al. (2021) · medRxiv · doi:10.1101/2021.06.23.21259381 · Cited by 3
Peiser, L. (2016) · Wiley eBooks · doi:10.1002/9780470015902.a0001214.pub3 · Cited by 3
Efferocytosis in the Tumor Microenvironment
Vaught, D., Stanford, J. C., & Cook, R. S. (2016) · Elsevier eBooks · doi:10.1016/b978-0-12-821618-7.30050-5 · Cited by 4
Kuroda, M., Nomura, K., Wada, A., Hatano, Y., Ogawa, M., Okamoto, S., Ishikawa, E., Izumi-Mishima, Y., Yasui‐Yamada, S., Tsutsumi, Y. M., et al. (2026) · npj Metabolic Health and Disease · doi:10.1038/s44324-026-00099-0 · Cited by 2
Miki, Y., Akimoto, J., Sato, A., & Fujiwara, Y. (2015) · Fundamental Toxicological Sciences · doi:10.2131/fts.2.111 · Cited by 2
Oxygenated Lipids: A Mode to WiPE Out Inflammation?
Hochreiter, A. E., & Ravichandran, K. S. (2012) · Immunity · doi:10.1016/j.immuni.2012.05.006 · Cited by 2
Kono, D. H., & Theofilopoulos, A. N. (2013) · Elsevier eBooks · doi:10.1016/b978-1-4377-1738-9.00020-7 · Cited by 2
TAG-FREE GLYCOSYLATED RHMFG-E8 AS A THERAPY FOR ACUTE KIDNEY INJURY
Zhang, F., Ma, G., Chaung, W. W., Jacob, A., Brenner, M., & Wang, P. (2024) · Shock · doi:10.1097/shk.0000000000002382 · Cited by 2
Kanuri, S. H. (2024) · The Egyptian Journal of Neurology Psychiatry and Neurosurgery · doi:10.1186/s41983-024-00853-5 · Cited by 2
Augmented CD47 expression impairs alloreactive T-cell clearance after allo-HCT
Flamann, C., Shaikh, H., Matos, C., Kreutz, M. P., Ali, H., Kern, M. A. G., Büttner-Herold, M. J., Jacobs, B., Völkl, S., Lischer, C., et al. (2025) · Blood · doi:10.1182/blood.2023023056 · Cited by 2
Autoimmune Diseases and the Role of MFG-E8
Hanayama, R. (2014) · Springer eBooks · doi:10.1007/978-94-017-8765-9_6 · Cited by 2
Self-citationImmune Regulation by Dead Cell Clearance
Tanaka, M., & Nishitai, G. (2015) · Current topics in microbiology and immunology · doi:10.1007/82_2015_472 · Cited by 2
Self-citationAutoimmunity, Atherosclerosis and Apoptotic Cell Clearance
Aprahamian, T. R. (2012) · InTech eBooks · doi:10.5772/25575 · Cited by 2
Xia, C., Campbell, K., Keselowsky, B. G., & Clare-Salzler, M. J. (2011) · InTech eBooks · doi:10.5772/22113 · Cited by 1
AFM Imaging in Physiological Environment: From Biomolecules to Living Cells
Cohen-Bouhacina, T., & Maali, A. (2008) · Springer eBooks · doi:10.1007/978-1-4020-4465-6_28 · Cited by 2
MFGE8 Does Not Influence Chorio-Retinal Homeostasis or Choroidal Neovascularization in vivo
Raoul, W., Poupel, L., Trégouët, D., Lavalette, S., Camelo, S., Keller, N., Krumeich, S., Calippe, B., Guillonneau, X., Béhar‐Cohen, F., et al. (2012) · PLoS ONE · doi:10.1371/journal.pone.0033244 · Cited by 2
Cell Survival and Death in Rheumatic Diseases
Elkon, K. B. (2013) · Elsevier eBooks · doi:10.1016/b978-1-4377-1738-9.00027-x · Cited by 2
B Cells Producing Pathogenic Autoantibodies
Zou, Y.-R., & Diamond, B. (2014) · Elsevier eBooks · doi:10.1016/b978-0-12-397933-9.00023-0 · Cited by 2
The Innate Immune System in SLE
Bossaller, L., & Marshak‐Rothstein, A. (2012) · Elsevier eBooks · doi:10.1016/b978-1-4377-1893-5.00006-6 · Cited by 2
Activating and Inhibitory FcγRs in Autoimmune Disorders
Nimmerjahn, F. (2013) · Elsevier eBooks · doi:10.1016/b978-0-12-394802-1.00011-x · Cited by 2
Lescoat, A., Cavalin, C., Lecureur, V., & Jégo, P. (2021) · La Revue de Médecine Interne · doi:10.1016/j.revmed.2021.03.005 · Cited by 2
Jin, Y., Ouyang, Y., Fan, X., Huang, J., Guo, W., & Miao, Y. (2022) · Animal Bioscience · doi:10.5713/ab.22.0120 · Cited by 2
You are what you eat and how you digest it! A discussion on inflammatory efferocytosis
Tanzer, M. C. (2023) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2023.1132696 · Cited by 2
B cell responses to apoptotic cells in MFG-E8-/- mice
Peng, Y. (2018) · PLoS ONE · doi:10.1371/journal.pone.0205172 · Cited by 2
Apoptotic Cells as a Source of Autoantigens
Casciola-Rosen, L. A., & Rosen, A. (2006) · Elsevier eBooks · doi:10.1016/b978-012595961-2/50018-4 · Cited by 2
Fadeel, B. (2005) · Springer eBooks · doi:10.1007/1-4020-3302-8_3 · Cited by 2
Proteins and Ions Compete for Membrane Interaction: the case of LactadherinPreprint
Lio, A. M. D., Paul, D., Jain, R., Morrissey, J. H., & Pogorelov, T. V. (2020) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2020.04.03.023838 · Cited by 2
Peiser, L., & Gordon, S. (2009) · Wiley eBooks · doi:10.1002/9780470015902.a0001214.pub2 · Cited by 2
Modes of Chemically Induced Cell Death
Aki, T., Unuma, K., Funakoshi, T., & Uemura, K. (2023) · Elsevier eBooks · doi:10.1016/b978-0-323-95488-4.00013-9 · Cited by 1
Serum level of lactadhedrin (MFGE8) in inflamatory bowel disease
Kozioł, K., Owczarek, D., Cibor, D., & Zwolinska-Wcislo, M. M. (2023) · Folia Medica Cracoviensia · doi:10.24425/fmc.2023.147212 · Cited by 1
Li, D., Mu, X., Ma, Y., Lu, W., & Wang, R. (2025) · Food Science and Human Wellness · doi:10.26599/fshw.2025.9250621 · Cited by 1
Vats, P., Kumar, R. C., Kumar, R., Kaushik, J. K., Mohanty, A. K., & Kumar, S. (2025) · Scientific Reports · doi:10.1038/s41598-025-00155-7 · Cited by 1
Bridging Inflammation and Repair: The Promise of MFG-E8 in Ischemic Stroke Therapy
Han, Y.-J., Lee, H., Geum, D., Kim, J., & Park, D. (2025) · International Journal of Molecular Sciences · doi:10.3390/ijms26178708 · Cited by 1
Jenkins, S. J., & Gregory, C. D. (2025) · Advances in experimental medicine and biology · doi:10.1007/978-3-031-92785-0_6 · Cited by 1
Efferocytosis: Signaling Pathways and New Therapeutic Strategies for Diseases
Wang, L., Ge, J., Wang, Z., Fang, Y., Jia, Y., Zhang, R., & Qin, Y. (2026) · MedComm · doi:10.1002/mco2.70764 · Cited by 1
FGFR1/KLB-MFG-E8 Maintains Microvascular Integrity and Adaptive Cardiac Remodeling
Gare, S. R., Alatawi, N. H. O., Chen, X., Zhang, J., Ross, C. A., Fonseka, O., Han, Y., Kaur, N., Ruiz‐Velasco, A., Zhao, X., et al. (2026) · Circulation Research · doi:10.1161/circresaha.125.327950 · Cited by 1
Beyond inflammation: Lipoxins; resolution of inflammation and regulation of fibrosis
MADERNA, P., & Godson, C. (2008) · Birkhäuser Basel eBooks · doi:10.1007/978-3-7643-7506-5_7 · Cited by 1
Methods Used to Study Apoptotic Cell Clearance
Trahtemberg, U., & Mevorach, D. (2009) · Springer eBooks · doi:10.1007/978-1-4020-9293-0_8 · Cited by 1
The future of lupus therapy modulating autoantigen recognition
Okamoto, A., Fujio, K., & Yamamoto, K. (2010) · Lupus · doi:10.1177/0961203310374306 · Cited by 1
Aziz, M., & Wang, P. (2014) · Springer eBooks · doi:10.1007/978-94-017-8765-9_9 · Cited by 1
Goldman, A. S., Chheda, S., Keeney, S. E., & Schmalstieg, F. C. (2016) · Elsevier eBooks · doi:10.1016/b978-0-323-35214-7.00129-3 · Cited by 1
Efferocytosis: An Interface between Apoptosis and Pathophysiology
Pratima, B. J., & Nalini, N. (2021) · IntechOpen eBooks · doi:10.5772/intechopen.97819 · Cited by 1
Anti-Inflammatory Role of MFG-E8 in the Intestinal Tract
Ishihara, S., Kusunoki, R., & Kinoshita, Y. (2014) · Springer eBooks · doi:10.1007/978-94-017-8765-9_8 · Cited by 1
Yang, N., & Goping, I. S. (2013) · Colloquium Series on Building Blocks of the Cell Cell Structure and Function · doi:10.4199/c00080ed1v01y201303bbc003 · Cited by 1
Cell Survival and Death in Rheumatic Diseases
Elkon, K. B. (2009) · Elsevier eBooks · doi:10.1016/b978-1-4160-3285-4.10024-5 · Cited by 1
Role of macrophages in prevention and control of diseases and their upregulation through cowpathy
Chauhan, R. S., & Chauhan, D. (2022) · International Journal of Cow Science · doi:10.18231/j.ijcs.2022.004 · Cited by 1
Han, C. W., Jeong, M. S., Lee, H. N., Hwang, E. Y., & Jang, S. B. (2024) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2024.149544 · Cited by 1
Gadiyar, V., Calianese, D. C., Pulica, R., Varsanyi, C., Wang, Z., Aquib, A., Choudhary, A. K., & Birge, R. B. (2024) · Methods in cell biology · doi:10.1016/bs.mcb.2024.10.003 · Cited by 1
Modes of Chemically Induced Cell Death
Aki, T., Noritake, K., Funakoshi, T., & Uemura, K. (2014) · Elsevier eBooks · doi:10.1016/b978-0-12-801238-3.01893-6 · Cited by 1
Isolation, bioinformatic analysis and tissue expression profile of a novel water buffalo gene-MFG-E8
ChunFeng, W., Liu, L., Huo, J., Li, D., Yuan, Y., Yuan, F., & Miao, Y. (2013) · Archives animal breeding/Archiv für Tierzucht · doi:10.7482/0003-9438-56-083 · Cited by 1
Cell Death and Autoimmune Disease
Gallucci, S., Caricchio, R., & Cohen, P. L. (2019) · Elsevier eBooks · doi:10.1016/b978-0-12-812102-3.00016-6 · Cited by 1
Does the RGD region of certain proteins affect metabolic activity?
Nagasaki, K., Gavrilova, O., Hajishengallis, G., & Somerman, M. J. (2022) · Frontiers in Dental Medicine · doi:10.3389/fdmed.2022.974862 · Cited by 1
Clearance of Apoptotic Cells – Mechanisms and Consequences
Marek, C. J., & Erwig, L. (2009) · Humana Press eBooks · doi:10.1007/978-1-60327-381-7_11 · Cited by 1
Developmental role and ligand binding properties of macrophage scavenger receptor MARCO
Chen, Y. (2006) · Figshare · Cited by 1
Tsabar, N., Gefen, A., Elias, S., & Frank, D. (2005) · Developmental Dynamics · doi:10.1002/dvdy.20308 · Cited by 1
B‐cell abnormality and systemic lupus erythematosus
Tsubata, T. (2006) · APLAR Journal of Rheumatology · doi:10.1111/j.1479-8077.2006.00240.x · Cited by 1
Mountz, J. D., Li, J., & Hsu, H. (2011) · Arthritis & Rheumatism · doi:10.1002/art.34321 · Cited by 1
Cell death: initiation, propagation and clearance
Krysko, D. V. (2006) · Ghent University Academic Bibliography (Ghent University) · Cited by 1
The regulation of B cell responses in systemic autoimmunity
Duhlin, A. (2017) · Figshare · Cited by 1
Phenotypic and Functional Characteristics of the IgM-IgD+ Naive B Cell Population in SLE Patients
Kim, J. J. (2010) · TSpace (University of Toronto) · Cited by 1
Wilmouth, J., Olabe, J., García-García, D., Lucas, C., Guiton, R., Roucher‐Boulez, F., Dufour, D., Damon‐Soubeyrand, C., Sahut‐Barnola, I., Pointud, J., et al. (2022) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2022.04.29.489846 · Cited by 1
The Role of MFG-E8 in Suppressing AT1-AA Production and Protecting Against PreeclampsiaPreprint
Xie, F., Shi, Z., Zhu, J., Lin, C., & Lin, F. (2023) · Preprints.org · doi:10.20944/preprints202312.1954.v1 · Cited by 1
Macrophage WDFY3, a protector against autoimmunityPreprint
Wu, X., Wang, Z., Croce, K. R., Li, F., Cui, J. G., D’Agati, V. D., Soni, R. K., Khalid, S., Saleheen, D., Tabas, I. A., et al. (2024) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2024.08.17.608411 · Cited by 1
Meshikhes, F. (2015) · ScholarlyCommons (University of Pennsylvania) · Cited by 1
Monogenic predisposition to systemic lupus erythematosus and efferocytosis
Guillet, S. (2019) · theses.fr (ABES) · doi:10.70675/f38861b1z1aa3z4ae5zaf45ze9aefb5c6af3 · Cited by 1
Modulation of dendritic cells and autoimmunity by apoptotic and necrotic cells
Miller, J. (2011) · OpenGrey (Institut de l'Information Scientifique et Technique) · Cited by 1
Fismen, S. (2011) · NORA - Norwegian Open Research Archives
Accumulation of Self-Antigens in Systemic Lupus Erythematosus
Yasutomo, K. (2006) · Springer eBooks · doi:10.1007/0-387-24534-0_20
The role of annexin A1 in secondary necrosis
Blume, K. (2011)
Apoptosis: A Potential Therapeutic Target in Sepsis and Non‐Infectious Systemic Inflammation
Chung, C., Swan, R., Perl, M., Wesche‐Soldato, D. E., & Ayala, A. (2008) · doi:10.1002/9783527626151.ch9
Apoptosis and Antiphospholipid Antibodies
Elkon, K. B., Mozaffarian, N., & Tishkevich, N. (2006) · Springer eBooks · doi:10.1007/1-84628-009-5_39
Mattsson, J. (2012) · Gothenburg University Publications Electronic Archive (Gothenburg University)
Lauber, K., & Wesselborg, S. (2006) · Wiley eBooks · doi:10.1002/9783527619665.ch24
Fas Pathway of Cell Death and B Cell Dysregulation in SLE
Paganelli, R., Paganelli, A., & Maria, C. (2012) · InTech eBooks · doi:10.5772/26509
The Annexin Code : revealing cardiovascular disease
Kietselaer, B. (2008) · Research Publications (Maastricht University) · doi:10.26481/dis.20080619bk
INNATE MECHANISMS REGULATING PERIPHERAL B CELL TOLERANCE
Wermeling, F. (2010) · Figshare
Dendritic cell responses to apoptotic cells : Is there life after death?
Johansson, U. (2010) · Figshare
Diamond, B. (2009) · Defense Technical Information Center (DTIC) · doi:10.21236/ada509183
Engulfment of Apoptotic Cells and Its Physiological Roles
Hanayama, R., Miyanishi, M., Yamaguchi, H., Suzuki, J., & Nagata, S. (2009) · Wiley eBooks · doi:10.1002/9780470015902.a0021580
Self-citationGallucci, S., Caricchio, R., & Cohen, P. L. (2013) · Elsevier eBooks · doi:10.1016/b978-0-12-384929-8.00017-4
Miki, Y., Hirano, K., & Beppu, M. (2012) · Bioscience Biotechnology and Biochemistry · doi:10.1271/bbb.120413
Macrophage Clearance Defects Prior to the Onset of Diabetes in NOD Mice
Geng, X. (2005) · Summit (Simon Fraser University)
Molecular, colloidal and cellular approaches to attack tumor vasculature
Fens, M. H. A. M. (2007) · Utrecht University Repository (Utrecht University)
Investigating Thiol-Dependent Processes in the Phagosome of Macrophages
Balce, D. R. (2014) · Libraries and Cultural Resources (University of Calgary) · doi:10.11575/prism/26648
Metadata
- Authors
- Hanayama, R., Tanaka, M., Miyasaka, K., Aozasa, K., Koike, M., Uchiyama, Y., & Nagata, S.
- Affiliations
- RIKEN (JP)
- Corresponding author
- Nagata, Shigekazu
- Venue
- Science
- Published
- 2004-05-21
- Volume
- 304
- Issue
- 5674
- Pages
- 1147-1150
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2037393136
- Cited by
- 992
- References
- 24
- Citations by year
- 2026: 10 · 2025: 22 · 2024: 32 · 2023: 37 · 2022: 34 · 2021: 48 · 2020: 36 · 2019: 36 · 2018: 41 · 2017: 46 · 2016: 32 · 2015: 42 · 2014: 51 · 2013: 64 · 2012: 59
- FWCI
- 21.82
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Science (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Immunology and Microbiology › Immunology › Phagocytosis and Immune Regulation
- Health Sciences › Medicine › Rheumatology › Systemic Lupus Erythematosus Research
- Health Sciences › Medicine › Hepatology › Liver Diseases and Immunity
- Keywords
- MFG-E8, efferocytosis, phosphatidylserine, macrophages, tingible body macrophages, germinal center, splenomegaly, glomerulonephritis, autoantibodies, autoimmune disease, B cell apoptosis
- MeSH terms
- CD68 Molecule, Animals, Antigens, Surface, Antibodies, Antinuclear, Autoantibodies, Autoimmune Diseases, B-Lymphocytes, Female, Glomerulonephritis, Macrophage Activation, Macrophages, Membrane Glycoproteins, Milk Proteins, Phagocytosis, Phosphatidylserines, Protein Binding, Spleen, Splenomegaly, T-Lymphocytes, Blotting, Northern, Antigens, Differentiation, Myelomonocytic, Antigens, CD, Apoptosis, Macrophages, Peritoneal, Gene Targeting, Germinal Center, In Situ Nick-End Labeling, Mice
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review