Autoimmune Disease and Impaired Uptake of Apoptotic Cells in MFG-E8-Deficient Mice

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MFG-E8/lactadherin regulates cyclins D1/D3 expression and enhances the tumorigenic potential of mammary epithelial cells

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Induction of TGF-β1 Synthesis by Macrophages in Response to Apoptotic Cells Requires Activation of the Scavenger Receptor CD36

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Genetic polymorphism in milk fat globule-EGF factor 8 (MFG-E8) is associated with systemic lupus erythematosus in human

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Prolonged Apoptotic Cell Accumulation in Germinal Centers of Mer-Deficient Mice Causes Elevated B Cell and CD4+ Th Cell Responses Leading to Autoantibody Production

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Restoration of Circulating MFGE8 (Milk Fat Globule-EGF Factor 8) Attenuates Cardiac Hypertrophy Through Inhibition of Akt Pathway

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Intracellular mammalian DNA stimulates myeloid dendritic cells to produce type I interferons predominantly through a toll‐like receptor 9–independent pathway

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Clearance phagocytosis by the retinal pigment epithelial during photoreceptor outer segment renewal: Molecular mechanisms and relation to retinal inflammation

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Defects in Germinal Center Selection in SLE

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Recombinant human MFG-E8 ameliorates colon damage in DSS- and TNBS-induced colitis in mice

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Macrophage‐fibroblast circuits in the spleen

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Maturation-induced down-regulation of MFG-E8 impairs apoptotic cell clearance and enhances endotoxin response

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Spatiotemporal transcriptomic maps of mouse intracerebral hemorrhage at single-cell resolution

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Characterizing follicular dendritic cells: A progress report

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Apoptotic PS to Phagocyte TIM-4: Eat Me

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Lack of the Long Pentraxin PTX3 Promotes Autoimmune Lung Disease but not Glomerulonephritis in Murine Systemic Lupus Erythematosus

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Enhanced efferocytosis by dendritic cells underlies memory T-cell expansion and susceptibility to autoimmune disease in CD300f-deficient mice

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Macrophagic Stabilin-1 Restored Disruption of Vascular Integrity Caused by Sepsis

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Roles and mechanisms of MFG-E8 in vascular aging-related diseases

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Milk fat globule EGF factor 8 restores mitochondrial function via integrin‐medicated activation of the FAK‐STAT3 signaling pathway in acute pancreatitis

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Gene expression profiling reveals the defining features of monocytes from septic patients with compensatory anti-inflammatory response syndrome

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Control of apoptosis in autoimmunity

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Efferocytosis Creates a Tumor Microenvironment Supportive of Tumor Survival and Metastasis

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Milk Fat Globule-Epidermal Growth Factor 8 Is Decreased in Intestinal Epithelium of Ulcerative Colitis Patients and Thereby Causes Increased Apoptosis and Impaired Wound Healing

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A new role for the P2X7 receptor: a scavenger receptor for bacteria and apoptotic cells in the absence of serum and extracellular ATP

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NMR solution structure of C2 domain of MFG-E8 and insights into its molecular recognition with phosphatidylserine

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The Dendritic Cell Receptor DNGR-1 Promotes the Development of Atherosclerosis in Mice

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A scavenging system against internal pathogens promoted by the circulating protein apoptosis inhibitor of macrophage (AIM)

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Employing New Cellular Therapeutic Targets for Alzheimers Disease: A Change for the Better?

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Inflammaging: triggers, molecular mechanisms, immunological consequences, sex differences, and cutaneous manifestations

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Apoptotic Cell Clearance in Development

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Recombinant human milk fat globule-EGF factor 8 produces dose-dependent benefits in sepsis

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Modulation of antigen presentation by intracellular trafficking

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Abl Kinase Inhibits the Engulfment of Apopotic Cells in Caenorhabditis elegans

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Significance of Glycosylphosphatidylinositol-anchored Protein Enrichment in Lipid Rafts for the Control of Autoimmunity

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Milk fat globule–EGF factor VIII ameliorates liver injury after hepatic ischemia-reperfusion

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Cross-Presentation of Cell-Associated Antigens by Mouse Splenic Dendritic Cell Populations

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Frontline Science: Tim-3-mediated dysfunctional engulfment of apoptotic cells in SLE

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Clearance of Apoptotic Bodies, NETs, and Biofilm DNA: Implications for Autoimmunity

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Human umbilical tissue-derived cells rescue retinal pigment epithelium dysfunction in retinal degeneration

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Inflammation and the apopto-phagocytic system

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Beyond Immunity: Underappreciated Functions of Intestinal Macrophages

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Sexually dimorphic activation of innate antitumor immunity prevents adrenocortical carcinoma development

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Loading of nuclear autoantigens prototypically recognized by systemic lupus erythematosus sera into late apoptotic vesicles requires intact microtubules and myosin light chain kinase activity

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Milk Fat Globule-Epidermal Growth Factor-8 Pretreatment Attenuates Apoptosis and Inflammation via the Integrin-β3 Pathway after Surgical Brain Injury in Rats

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Massive Apoptosis in Lymphoid Organs in Animal Models for Primary and Secondary Progressive Multiple Sclerosis

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Identification of poly-reactive natural IgM antibody that recognizes late apoptotic cells and promotes phagocytosis of the cells

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Essential Role of MFG-E8 for Phagocytic Properties of Microglial Cells

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Protective effect of milk fat globule-epidermal growth factor-factor VIII after renal ischemia-reperfusion injury in mice*

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Effect of talaporfin sodium-mediated photodynamic therapy on cell death modalities in human glioblastoma T98G cells

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The evolving roles of pericyte in early brain injury after subarachnoid hemorrhage

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Osteopontin in Spontaneous Germinal Centers Inhibits Apoptotic Cell Engulfment and Promotes Anti-Nuclear Antibody Production in Lupus-Prone Mice

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MFG-E8 overexpression promotes colorectal cancer progression via AKT/MMPs signalling

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MFG-E8 and HMGB1 Are Involved in the Mechanism Underlying Alcohol-Induced Impairment of Macrophage Efferocytosis

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Lipoxin A4 suppresses angiotensin II type 1 receptor autoantibody in preeclampsia via modulating caspase-1

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Prolactin induces MFG-E8 production in macrophages via transcription factor C/EBPβ-dependent pathway

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Role of lactadherin in the clearance of phosphatidylserine‐expressing red blood cells

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Anti-Inflammatory Neutrophils Reprogram Macrophages toward a Pro-Healing Phenotype with Increased Efferocytosis Capacity

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Dys-regulated phosphatidylserine externalization as a cell intrinsic immune escape mechanism in cancer

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Epistatic Interactions Between Mutations of Deoxyribonuclease 1-Like 3 and the Inhibitory Fc Gamma Receptor IIB Result in Very Early and Massive Autoantibodies Against Double-Stranded DNA

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Production of the long and short forms of MFG-E8 by epidermal keratinocytes

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Identification of TLT2 as an Engulfment Receptor for Apoptotic Cells

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Expression of milk fat globule EGF-factor 8 (MFG-E8) mRNA and protein in the human endometrium and its regulation by prolactin

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Incomplete clearance of apoptotic cells in systemic lupus erythematosus: pathogenic role and potential biomarker

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Autoreactive MZ and B-1 B-cell activation by Faslpr is coincident with an increased frequency of apoptotic lymphocytes and a defect in macrophage clearance

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Missing in action—The meaning of cell death in tissue damage and inflammation

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Some news from the unknown soldier, the Peyer’s patch macrophage

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Insight into the role of phosphatidylserine in complement-mediated synapse loss in Alzheimer’s disease

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Non-coding RNAs and lipids mediate the function of extracellular vesicles in cancer cross-talk

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Leveraging Antibody, B Cell and Fc Receptor Interactions to Understand Heterogeneous Immune Responses in Tuberculosis

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Macrophage metabolic rewiring improves heme-suppressed efferocytosis and tissue damage in sickle cell disease

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Cigarette smoke attenuates phagocytic ability of macrophages through down-regulating Milk fat globule-EGF factor 8 (MFG-E8) expressions

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Carbohydrate chains and phosphatidylserine successively work as signals for apoptotic cell removal

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Tyro3, Axl, Mertk receptor-mediated efferocytosis and immune regulation in the tumor environment

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Comparison of Milk Fat Globule Membrane (MFGM) Proteins of Chianina and Holstein Cattle Breed Milk Samples Through Proteomics Methods

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Polymer nanotherapeutics to correct autoimmunity

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SED1 function during mammalian sperm–egg adhesion

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Retardation of removal of radiation-induced apoptotic cells in developing neural tubes in macrophage galactose-type C-type lectin-1-deficient mouse embryos

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Integrin α PAT-2/CDC-42 Signaling Is Required for Muscle-Mediated Clearance of Apoptotic Cells in Caenorhabditis elegans

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Nuclear Receptors and Clearance of Apoptotic Cells: Stimulating the Macrophage’s Appetite

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MFG-E8 inhibits neutrophil migration through αvβ3-integrin-dependent MAP kinase activation

Aziz, M., Yang, W., Corbo, L., Chaung, W. W., Matsuo, S., & Wang, P. (2015) · International Journal of Molecular Medicine · doi:10.3892/ijmm.2015.2196 · Cited by 34

Efferocytosis capacities of blood monocyte‐derived macrophages in systemic sclerosis

Ballerie, A., Lescoat, A., Augagneur, Y., Lelong, M., Morzadec, C., Cazalets, C., Jouneau, S., Fardel, O., Vernhet, L., Jégo, P., et al. (2018) · Immunology and Cell Biology · doi:10.1111/imcb.12217 · Cited by 34

Knockdown of milk‐fat globule EGF factor‐8 suppresses glioma progression in GL261 glioma cells by repressing microglial M2 polarization

Wu, J., Yang, H., Cheng, J., Zhang, L., Ke, Y., Zhu, Y., Wang, C., Zhang, X., Zhen, X., & Zheng, L. T. (2020) · Journal of Cellular Physiology · doi:10.1002/jcp.29712 · Cited by 34

Erythrophagocytosis by angiogenic endothelial cells is enhanced by loss of erythrocyte deformability

Fens, M. H. A. M., Storm, G., Pelgrim, R. C. M., Ultee, A., Byrne, A. T., Gaillard, S., van Solinge, W. W., & Schiffelers, R. M. (2010) · Experimental Hematology · doi:10.1016/j.exphem.2010.02.001 · Cited by 34

Abnormal Production of Pro- and Anti-Inflammatory Cytokines by Lupus Monocytes in Response to Apoptotic Cells

Sule, S. D., Rosen, A., Petri, M., Akhter, E., & Andrade, F. (2011) · PLoS ONE · doi:10.1371/journal.pone.0017495 · Cited by 34

Dendritic Cells in Systemic Lupus Erythematosus

Seitz, H., & Matsushima, G. K. (2010) · International Reviews of Immunology · doi:10.3109/08830181003602507 · Cited by 35

The role of nucleotides in apoptotic cell clearance: implications for disease pathogenesis

Chekeni, F. B., & Ravichandran, K. S. (2010) · Journal of Molecular Medicine · doi:10.1007/s00109-010-0673-7 · Cited by 34

Necrotizing infundibulo-hypophysitis: an entity too rare to be true?

Gutenberg, A., Caturegli, P., Metz, I., Martínez, R., Mohr, A., Brück, W., & Rohde, V. (2011) · Pituitary · doi:10.1007/s11102-011-0307-2 · Cited by 33

PTEN Negatively Regulates Engulfment of Apoptotic Cells by Modulating Activation of Rac GTPase

Mondal, S., Ghosh-Roy, S., Loison, F., Li, Y., Jia, Y., Harris, C. E., Williams, D. A., & Luo, H. R. (2011) · The Journal of Immunology · doi:10.4049/jimmunol.1100484 · Cited by 33

Association of placenta‐derived extracellular vesicles with pre‐eclampsia and associated hypercoagulability: a clinical observational study

Chen, Y., Huang, P., Han, C., Li, J., Liu, L., Zhao, Z., Gao, Y., Qin, Y., Xu, Q., Ye, Y., et al. (2020) · BJOG An International Journal of Obstetrics & Gynaecology · doi:10.1111/1471-0528.16552 · Cited by 33

Prix Fixe: Efferocytosis as a Four-Course Meal

Martinez, J. (2015) · Current topics in microbiology and immunology · doi:10.1007/82_2015_467 · Cited by 36

Taking insult from injury: Lipoxins and lipoxin receptor agonists and phagocytosis of apoptotic cells

MADERNA, P., & Godson, C. (2005) · Prostaglandins Leukotrienes and Essential Fatty Acids · doi:10.1016/j.plefa.2005.05.004 · Cited by 33

Neutrophils Accelerate Macrophage-Mediated Digestion of Apoptotic Cells In Vivo as Well as In Vitro

Iyoda, T., Nagata, K., Akashi, M., & Kobayashi, Y. (2005) · The Journal of Immunology · doi:10.4049/jimmunol.175.6.3475 · Cited by 33

Correction: Abl Kinase Inhibits the Engulfment of Apopotic Cells in Caenorhabditis elegans

Hurwitz, M. E., Vanderzalm, P. J., Bloom, L., Goldman, J., Garriga, G., & Horvitz, H. R. (2009) · PLoS Biology · doi:10.1371/annotation/2259f958-a68e-4e57-92b5-2ef003070cf1 · Cited by 33

Apoptotic Cells Ameliorate Chronic Intestinal Inflammation by Enhancing Regulatory B-cell Function

Ansary, M. M. U., Ishihara, S., Oka, A., Kusunoki, R., Oshima, N., Yuki, T., Kawashima, K., Maegawa, H., Kashiwagi, N., & Kinoshita, Y. (2014) · Inflammatory Bowel Diseases · doi:10.1097/mib.0000000000000240 · Cited by 33

Tolerogenic Dendritic Cells: Key Regulators of Peripheral Tolerance in Health and Disease

Saei, A., & Hadjati, J. (2013) · International Archives of Allergy and Immunology · doi:10.1159/000350328 · Cited by 39

MFG-E8-Dependent Clearance of Apoptotic Cells, and Autoimmunity Caused by Its Failure

Hanayama, R., Miyasaka, K., Nakaya, M., & Nagata, S. (2005) · KARGER eBooks · doi:10.1159/000090780 · Cited by 69

Cell Death and Autoimmune Disease

(2004) · Science s STKE · doi:10.1126/stke.2342004tw188

Autoimmune Diseases and the Role of MFG-E8

Hanayama, R. (2014) · Springer eBooks · doi:10.1007/978-94-017-8765-9_6 · Cited by 2

Apoptotic cell clearance by phagocytes

Tanaka, M. (2005) · International Congress Series · doi:10.1016/j.ics.2005.07.080 · Cited by 4

Autoimmunity in MFG-E8-deficient mice is associated with altered trafficking and enhanced cross-presentation of apoptotic cell antigens.

Peng, Y.-F., & Elkon, K. (2011) · Journal of Clinical Investigation · doi:10.1172/jci43254 · Cited by 96