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In vivo demonstration that α-synuclein oligomers are toxic

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PolyQ Proteins Interfere with Nuclear Degradation of Cytosolic Proteins by Sequestering the Sis1p Chaperone

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Metazoan Hsp70 machines use Hsp110 to power protein disaggregation

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Assembly and Function of Heterotypic Ubiquitin Chains in Cell-Cycle and Protein Quality Control

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The insulin paradox: aging, proteotoxicity and neurodegeneration

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Principles of Protein Stability and Their Application in Computational Design

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Hormetic heat stress and HSF-1 induce autophagy to improve survival and proteostasis in C. elegans

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Widespread aggregation and neurodegenerative diseases are associated with supersaturated proteins

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Prion Switching in Response to Environmental Stress

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Mechanisms and Functions of Spatial Protein Quality Control

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Ablation of the UPR-Mediator CHOP Restores Motor Function and Reduces Demyelination in Charcot-Marie-Tooth 1B Mice

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Huntington's DiseasePreprint

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Folding and Misfolding of Human Membrane Proteins in Health and Disease: From Single Molecules to Cellular Proteostasis

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Shaping proteostasis at the cellular, tissue, and organismal level

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The chaperonin TRiC blocks a huntingtin sequence element that promotes the conformational switch to aggregation

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