The DOI matches its Crossref record; 6 of the 6 references it cites were found in a registry or an index.
Antibiotics for Emerging Pathogens
Open accessAbstract
Toward New Scaffolds: Most existing antibiotics are derived from a small number of core molecular structures or scaffolds. As more and more pathogens emerge that are resistant to existing antibiotics, Fischbach and Walsh (p. 1089 ) review why renewed efforts must be made to find not only new antibiotics but new scaffolds. Approaches in the areas of natural products, synthesis, and target-based discovery are all yielding promising antibiotics candidates. The battle against resistance should also involve researching narrow-spectrum antibiotics and using combination therapies to extend the usefulness of drugs with high intrinsic resistance rates.
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Cited by
Ribosome-targeting antibiotics and mechanisms of bacterial resistance
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Metadata
- Authors
- Fischbach, M. A., & Walsh, C. T.
- Venue
- Science
- Published
- 2009-08-28
- Volume
- 325
- Issue
- 5944
- Pages
- 1089-1093
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W1970798262
- Cited by
- 1,777
- References
- 6
- FWCI
- 73.43
- Type
- journal article
- Language
- en
- Open access
- green
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
