The DOI matches its Crossref record.
Dorsal , an Embryonic Polarity Gene in Drosophila , Is Homologous to the Vertebrate Proto-Oncogene, c- rel
Abstract
The Drosophila gene, dorsal , is a maternal effect locus that is essential for the establishment of dorsal-ventral polarity in the developing embryo. The dorsal protein was predicted from the complementary DNA sequence; it is almost 50 percent identical, over an extensive region, to the protein encoded by the avian oncogene v- rel , its cellular homolog, c- rel , and a human c- rel fragment. The oncogene v- rel is highly oncogenic in avian lymphoid, spleen, and bone marrow cells.
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Metadata
- Authors
- Steward, R.
- Venue
- Science
- Published
- 1987-10-30
- Volume
- 238
- Issue
- 4827
- Pages
- 692-694
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2076854746
- Cited by
- 484
- References
- 0
- FWCI
- 7.00
- Type
- journal article
- Language
- en
- Open access
- closed
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