An Increased Percentage of Long Amyloid β Protein Secreted by Familial Amyloid β Protein Precursor (βApp 717 ) Mutants

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Items 101–118 of 118

1. Intracellular Accumulation of Insoluble, Newly Synthesized Aβn-42 in Amyloid Precursor Protein-transfected Cells That Have Been Treated with Aβ1–42
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2. Amyloid‐β protein (Aβ) Glu11 is the major β‐secretase site of β‐site amyloid‐β precursor protein‐cleaving enzyme 1(BACE1), and shifting the cleavage site to Aβ Asp1 contributes to Alzheimer pathogenesis
   Deng, Yu, Wang, Zhe, Wang, Ruitao, Zhang, Xiaozhu, Zhang, Shuting, Wu, Yili, Staufenbiel, Matthias, Cai, Fang, Song, Weihong · 2013 · European Journal of Neuroscience
3. Additive Effects of PS1 and APP Mutations on Secretion of the 42-Residue Amyloid β-Protein
   Citron, Martin, Eckman, Christopher B., Diehl, Thekla S., Corcoran, Chris, Ostaszewski, Beth L., Xia, Weiming, Levesque, Georges, St. George Hyslop, Peter, Younkin, Steven G., Selkoe, Dennis J. · 1998 · Neurobiology of Disease
4. The impact of Aβ-plaques on cortical cholinergic and non-cholinergic presynaptic boutons in alzheimer's disease-like transgenic mice
   Hu, L, Wong, T.P, Côté, S.L, Bell, K.F.S, Cuello, A.C · 2003 · Neuroscience
5. Cerebral white matter lesions – associations with Aβ isoforms and amyloid PET
   van Westen, Danielle, Lindqvist, Daniel, Blennow, Kaj, Minthon, Lennart, Nägga, Katarina, Stomrud, Erik, Zetterberg, Henrik, Hansson, Oskar · 2016 · Scientific Reports
6. Evidence for lymphatic Aβ clearance in Alzheimer's transgenic mice
   Pappolla, Miguel, Sambamurti, Kumar, Vidal, Ruben, Pacheco-Quinto, Javier, Poeggeler, Burkhard, Matsubara, Etsuro · 2014 · Neurobiology of Disease
7. Alzheimer’s Disease as a Major Public Health Concern: Role of Dietary Saponins in Mitigating Neurodegenerative Disorders and Their Underlying Mechanisms
   Abduljawad, Asaad A., Elawad, Mohammed Ahmed, Elkhalifa, Modawy Elnour Modawy, Ahmed, Alshebli, Hamdoon, Alashary Adam Eisa, Salim, Liga Hasan Mohammed, Ashraf, Muhammad, Ayaz, Muhammad, Hassan, Syed Shams ul, Bungau, Simona · 2022 · Molecules
8. Turning the tide on Alzheimer’s disease: modulation of γ-secretase
   Luo, Joanna E., Li, Yue-Ming · 2022 · Cell & Bioscience
9. Modulation of ABCA1 by an LXR Agonist Reduces Beta-Amyloid Levels and Improves Outcome after Traumatic Brain Injury
   Loane, David J., Washington, Patricia M., Vardanian, Lilit, Pocivavsek, Ana, Hoe, Hyang-Sook, Duff, Karen E., Cernak, Ibolja, Rebeck, G. William, Faden, Alan I., Burns, Mark P. · 2011 · Journal of Neurotrauma
10. The levels of cerebrospinal fluid Aβ40 and Aβ42(43) are regulated age-dependently
    Shoji, M., Kanai, M., Matsubara, E., Tomidokoro, Y., Shizuka, M., Ikeda, Y., Ikeda, M., Harigaya, Y., Okamoto, K., Hirai, S. · 2001 · Neurobiology of Aging
11. Mechanisms of memory loss in Aβ and tau mouse models
    Ashe, K.H. · 2005 · Biochemical Society Transactions
12. High throughput screens for the identification of compounds that alter the accumulation of the Alzheimer's amyloid β peptide (Aβ)
    Haugabook, S.J, Yager, D.M, Eckman, E.A, Golde, T.E, Younkin, S.G, Eckman, C.B · 2001 · Journal of Neuroscience Methods
13. Amyloid β-peptide in cerebrospinal fluid in individuals with the Swedish Alzheimer amyloid precursor protein mutation
    Lannfelt, Lars, Basun, Hans, Vigo-Pelfrey, Carmen, Wahlund, Lars-Olof, Winblad, Bengt, Lieberburg, Ivan, Schenk, Dale · 1995 · Neuroscience Letters
14. Amyloid β Protein in Plasma as a Diagnostic Marker for Alzheimer’s Disease
    Iwatsubo, T. · 1998 · Neurobiology of Aging
15. Tyrosine phosphatase STEP61 negatively regulates amyloid β‐mediated ERK/CREB signaling pathways via α7 nicotinic acetylcholine receptors
    Zhang, Lin, Xie, Jing‐Wei, Yang, Jing, Cao, Yun‐Peng · 2013 · Journal of Neuroscience Research
16. A flow cytometry–based in vitro assay reveals that formation of apolipoprotein E (ApoE)–amyloid beta complexes depends on ApoE isoform and cell type
    Kara, Eleanna, Marks, Jordan D., Roe, Allyson D., Commins, Caitlin, Fan, Zhanyun, Calvo-Rodriguez, Maria, Wegmann, Susanne, Hudry, Eloise, Hyman, Bradley T. · 2018 · Journal of Biological Chemistry
17. Apolipoprotein E, Aβ‐Amyloid, and the Molecular Pathology of Alzheimer's Disease Therapeutic Implicationsa
    KAPLITT, MICHAEL, GOURAS, GUNNAR K., MAKIMURA, HIDEO, JOVANOVIC, JASMINA, SWEENEY, DAVID, GREENGARD, PAUL, RELKIN, NORMAN R., GANDY, SAMUEL · 1996 · Annals of the New York Academy of Sciences
18. A new brain metalloendopeptidase which degrades the Alzheimer ß-amyloid 1-40 peptide producing soluble fragments without neurotoxic effects
    Carvalho, K.M., França, M.S.F., Camarão, G.C., Ruchon, A.F. · 1997 · Brazilian Journal of Medical and Biological Research