The DOI matches its Crossref record; 3 of the 3 references it cites were found in a registry or an index.
An RNA biosensor for imaging the first round of translation from single cells to living animals
Open accessAbstract
Measuring translation in space and time: The ribosome translates the information contained within messenger RNAs (mRNAs) into proteins. When and where ribosomes encounter mRNAs can regulate gene expression. Halstead et al. developed an RNA biosensor that allows single molecules of mRNAs that have never been translated to be distinguished from ones that have undergone translation by the ribosome in living cells (see the Perspective by Popp and Maquat). The authors demonstrated the utility of their technique by examining the spatial and temporal regulation of translation in single cells and in Drosophila oocytes during development. Science , this issue p. 1367 ; see also p. 1316
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Cites
Mfold web server for nucleic acid folding and hybridization prediction
Zuker, M. (2003) · Nucleic Acids Research · doi:10.1093/nar/gkg595 · Cited by 13,404
Global quantification of mammalian gene expression control
Schwanhäusser, B., Busse, D., Li, N., Dittmar, G., Schuchhardt, J., Wolf, J., Chen, W., & Selbach, M. (2011) · Nature · doi:10.1038/nature10098 · Cited by 6,566
Genome-Wide Analysis in Vivo of Translation with Nucleotide Resolution Using Ribosome Profiling
Ingolia, N. T., Ghaemmaghami, S., Newman, J. R. S., & Weissman, J. S. (2009) · Science · doi:10.1126/science.1168978 · Cited by 3,853
Research works printed but not linked: 34
- 10.1126/science.1202142 · DOI · Paper page
- 10.1146/annurev.biophys.37.032807.125928 · DOI · Paper page
- 10.1101/cshperspect.a012310 · DOI
- 10.1038/nmeth.2305 · DOI · Paper page
- 10.1038/nature04530 · DOI · Paper page
- 10.1073/pnas.93.8.3346 · DOI · Paper page
- 10.1261/rna.038356.113 · DOI
- 10.1083/jcb.201112145 · DOI · Paper page
- 10.1126/science.1099754 · DOI · Paper page
- 10.1038/ncb2056 · DOI · Paper page
- 10.1016/0006-291X(66)90390-1 · doi:10.1016/0006-291x(66)90390-1
- 10.1101/gad.209635.112 · DOI
- 10.1016/j.molcel.2009.11.020 · DOI · Paper page
- 10.1016/j.tibs.2013.07.004 · DOI · Paper page
- 10.1083/jcb.200502088 · DOI · Paper page
- 10.1091/mbc.E08-05-0499 · DOI · Paper page
- 10.1101/gad.17355911 · DOI · Paper page
- 10.1038/358387a0 · DOI · Paper page
- 10.1016/0092-8674(95)90393-3 · DOI · Paper page
- 10.1242/dev.121.11.3723 · DOI · Paper page
- 10.1016/j.devcel.2013.06.011 · DOI
- 10.1016/j.ydbio.2008.07.033 · DOI
- 10.1016/j.cell.2013.04.056 · DOI
- 10.1016/j.cell.2007.05.028 · DOI · Paper page
- 10.1016/j.cell.2014.09.039 · DOI · Paper page
- 10.1021/bc900249e · DOI
- 10.7554/eLife.03939 · DOI · Paper page
- 10.7554/eLife.00750 · DOI
- 10.1016/j.bpj.2012.05.017 · DOI · Paper page
- 10.1038/nmeth.1551 · DOI · Paper page
- 10.1038/nmeth.3256 · DOI · Paper page
- 10.1093/nar/gkp108 · DOI
- 10.1016/S1097-2765(00)80143-4 · DOI · Paper page
- 10.1242/dev.129.15.3705 · doi:10.1242/dev.129.15.3705
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Self-citationReal-Time Imaging of Translation on Single mRNA Transcripts in Live Cells
Wang, C., Han, B., Zhou, R., & Zhuang, X. (2016) · Cell · doi:10.1016/j.cell.2016.04.040 · Cited by 359
Control of Transcript Variability in Single Mammalian Cells
Battich, N., Stoeger, T., & Pelkmans, L. (2015) · Cell · doi:10.1016/j.cell.2015.11.018 · Cited by 324
The Dynamics of mRNA Turnover Revealed by Single-Molecule Imaging in Single Cells
Horvathova, I., Voigt, F., Kotrys, A. V., Zhan, Y., Artus-Revel, C. G., Eglinger, J., Stadler, M. B., Giorgetti, L., & Chao, J. A. (2017) · Molecular Cell · doi:10.1016/j.molcel.2017.09.030 · Cited by 225
Self-citationSpatially resolved single-cell translatomics at molecular resolution
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Metadata
- Authors
- Halstead, J. M., Lionnet, T., Wilbertz, J. H., Wippich, F., Ephrussi, A., Singer, R. H., & Chao, J. A.
- Venue
- Science
- Published
- 2015-03-20
- Volume
- 347
- Issue
- 6228
- Pages
- 1367-1671
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W1983358637
- Cited by
- 266
- References
- 3
- FWCI
- 14.28
- Type
- journal article
- Language
- en
- Open access
- green
- Funders
- NIH (NS83085, EB013571, GM57071)
- Howard Hughes Medical Institute
- Novartis Research Foundation
- European Molecular Biology Laboratory
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- Halstead, J. M., Lionnet, T., Wilbertz, J. H., Wippich, F., Ephrussi, A., Singer, R. H., & Chao, J. A. (2015). An RNA biosensor for imaging the first round of translation from single cells to living animals. Science. https://doi.org/10.1126/science.aaa3380
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