Individual intestinal symbionts induce a distinct population of RORγ + regulatory T cells

Sefik, Esen, Geva-Zatorsky, Naama, Oh, Sungwhan, Konnikova, Liza, Zemmour, David, McGuire, Abigail Manson, Burzyn, Dalia, Ortiz-Lopez, Adriana +9 more·2015·Science

DOI 10.1126/science.aaa9420

Cited by (879)

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mTOR coordinates transcriptional programs and mitochondrial metabolism of activated Treg subsets to protect tissue homeostasis
Nicole M. Chapman, Hu Zeng, Thanh-Long M. Nguyen, Yanyan Wang, Peter Vogel, Yogesh Dhungana, Xiaojing Liu, Geoffrey A. M. Neale, Jason W. Locasale, Hongbo Chi · 2018 · Nature Communications
Revisiting the gut–joint axis: links between gut inflammation and spondyloarthritis
Eric Gracey, Lars Vereecke, Dermot P.B. McGovern, Mareike Fröhling, Georg Andreas Schett, Silvio Danese, Martine De Vos, Filip E Van den Bosch, Dirk Sw Elewaut · 2020 · Nature Reviews Rheumatology
Immunity by equilibrium
Gérard Eberl · 2016 · Nature reviews. Immunology
The Stromal Intervention: Regulation of Immunity and Inflammation at the Epithelial-Mesenchymal Barrier
Nowarski, Roni, Jackson, Ruaidhrí, Flavell, Richard A. · 2017 · Cell
Regionalized Development and Maintenance of the Intestinal Adaptive Immune Landscape
William W. Agace, Kathy D. McCoy · 2017 · Immunity
Crosstalk between bile acid-activated receptors and microbiome in entero-hepatic inflammation
Morgane M. Thibaut, Laure B. Bindels · 2022 · Trends in Molecular Medicine
Profound Treg perturbations correlate with COVID-19 severity
Silvia Galván-Peña, Juliette Léon, Kaitavjeet Chowdhary, Daniel A. Michelson, Brinda Vijaykumar, Liang Yang, Angela M. Magnuson, Felicia Chen, Zachary Manickas-Hill, Alicja K. Trocha et al. · 2021 · Proceedings of the National Academy of Sciences
Alterations in microbiota of patients with COVID-19: potential mechanisms and therapeutic interventions
Bin Wang, Lei Zhang, Yongqiang Wang, Tong Dai, Ziran Qin, Fangfang Zhou, Long Zhang · 2022 · Signal Transduction and Targeted Therapy
The maternal gut microbiome in pregnancy: implications for the developing immune system
Omry Koren, Liza Konnikova, Petter Brodin, Indira U. Mysorekar, María Carmen Collado · 2023 · Nature Reviews Gastroenterology & Hepatology
c-Maf-dependent Treg cell control of intestinal TH17 cells and IgA establishes host–microbiota homeostasis
Christian Neumann, Jonas Blume, Urmi Roy, Peggy P. Teh, Ajithkumar Vasanthakumar, Alexander V. Beller, Yang Liao, Frederik Heinrich, Teresita L. Arenzana, Jason A. Hackney et al. · 2019 · Nature Immunology
The Aryl Hydrocarbon Receptor Preferentially Marks and Promotes Gut Regulatory T Cells
Jian Ye, Ju Qiu, John W. Bostick, Aki Ueda, Hilde Schjerven, Shiyang Li, Christian Jobin, Zongming E. Chen, Liang Zhou · 2017 · Cell Reports
Regulatory CD4 + T Cells Recognize Major Histocompatibility Complex Class II Molecule–Restricted Peptide Epitopes of Apolipoprotein B
Takayuki Kimura, Kouji Kobiyama, Holger Winkels, Kevin Y. Tse, Jacqueline F. Miller, Melanie Vassallo, Dennis Wolf, Christian Ryden, Marco Orecchioni, Thamotharampillai Dileepan et al. · 2018 · Circulation
An Immunologic Mode of Multigenerational Transmission Governs a Gut Treg Setpoint
Deepshika Ramanan, Esen Sefik, Silvia Galván-Peña, Meng Wu, Liang Yang, Zhen Yang, Aleksandar David Kostic, Tatyana V. Golovkina, Dennis Lee Kasper, Diane J. Mathis et al. · 2020 · Cell
Dynamic balance between master transcription factors determines the fates and functions of CD4 T cell and innate lymphoid cell subsets
Fang, Difeng, Zhu, Jinfang · 2017 · Journal of Experimental Medicine
Insulin-Like Growth Factors Are Key Regulators of T Helper 17 Regulatory T Cell Balance in Autoimmunity
Daniel Francis Ditoro, Stacey N. Harbour, Jennifer K. Bando, Gloria A. Benavides, Steven J. Witte, Vincent A. Laufer, Carson E. Moseley, Jeffery R. Singer, Blake F. Frey, Henrietta Turner et al. · 2020 · Immunity
The microbiota, immunoregulation, and mental health: implications for public health
Lowry, Christopher A., Smith, David G., Siebler, Philip H., Schmidt, Dominic, Stamper, Christopher E., Hassell, James E., Yamashita, Paula S., Fox, James H., Reber, Stefan O., Brenner, Lisa A. et al. · 2016 · Current Environmental Health Reports
Gut CD4+ T cell phenotypes are a continuum molded by microbes, not by TH archetypes
Evgeny Kiner, Elijah Willie, Brinda Vijaykumar, Kaitavjeet Chowdhary, Hugo Schmutz, Jodie S. Chandler, Alexandra Schnell, Pratiksha I. Thakore, Graham S Le Gros, Sara Mostafavi et al. · 2021 · Nature Immunology
Analyses of a Mutant Foxp3 Allele Reveal BATF as a Critical Transcription Factor in the Differentiation and Accumulation of Tissue Regulatory T Cells
Norihito Hayatsu, Takahisa Miyao, Masashi Tachibana, Ryuichi Murakami, Akihiko Kimura, Takako Katō, Eiryo Kawakami, Takaho A. Endo, Ruka Setoguchi, Hiroshi Watarai et al. · 2017 · Immunity
Interleukin-6 produced by enteric neurons regulates the number and phenotype of microbe-responsive regulatory T cells in the gut
Yan, Yiqing, Ramanan, Deepshika, Rozenberg, Milena, McGovern, Kelly, Rastelli, Daniella, Vijaykumar, Brinda, Yaghi, Omar, Voisin, Tiphaine, Mosaheb, Munir, Chiu, Isaac et al. · 2021 · Immunity
Interleukin-2 signaling in the regulation of T cell biology in autoimmunity and cancer
Acacia N. Shouse, Kathryn M LaPorte, Thomas R. Malek · 2024 · Immunity
Single-cell chromatin accessibility landscape identifies tissue repair program in human regulatory T cells
Delacher, Michael, Simon, Malte, Sanderink, Lieke, Hotz-Wagenblatt, Agnes, Wuttke, Marina, Schambeck, Kathrin, Schmidleithner, Lisa, Bittner, Sebastian, Pant, Asmita, Ritter, Uwe et al. · 2021 · Immunity
Flicr , a long noncoding RNA, modulates Foxp3 expression and autoimmunity
David Zemmour, Alvin Pratama, Scott M. Loughhead, Diane J. Mathis, Christophe O. Benoist · 2017 · Proceedings of the National Academy of Sciences
Molecular diversification of regulatory T cells in nonlymphoid tissues
Joanna R. DiSpirito, David Zemmour, Deepshika Ramanan, Jun Cho, Rapolas Žilionis, Allon Moshe Klein, Christophe O. Benoist, Diane J. Mathis · 2018 · Science Immunology
Regulatory T-cell therapy in Crohn’s disease: challenges and advances
Jennifer Clough, Omer S. Omer, Scott Tasker, Graham M. Lord, Peter Miles Irving · 2020 · Gut
Gut microbiota derived bile acid metabolites maintain the homeostasis of gut and systemic immunity
Lei Su, Yunhuan Gao, Rongcun Yang · 2023 · Frontiers in Immunology
The Microbiome and Food Allergy
Onyinye I. Iweala, Cathryn Nagler‐Anderson · 2019 · Annual Review of Immunology
Goblet cell associated antigen passages support the induction and maintenance of oral tolerance
Devesha Hrishikesh Kulkarni, Jenny K. Gustafsson, Kathryn A. Knoop, Keely G. McDonald, Shay S. Bidani, Jazmyne E. Davis, Alexandria N. Floyd, Simon Patrick Hogan, Chyi‐Song Hsieh, Rodney D. Newberry · 2019 · Mucosal Immunology
The gut microbiome and mental health: implications for anxiety- and trauma-related disorders
Malan-Muller, Stefanie, Valles-Colomer, Mireia, Raes, Jeroen, Lowry, Christopher A., Seedat, Soraya, Hemmings, Sian M.J. · 2018 · OMICS: A Journal of Integrative Biology
Regulatory T cell adaptation in the intestine and skin
Natasha Whibley, Andrea Tucci, Fiona M. Powrie · 2019 · Nature Immunology
ICOS+ Tregs: A Functional Subset of Tregs in Immune Diseases
Dan-Yang Li, Xian‐Zhi Xiong · 2020 · Frontiers in Immunology
Roles of Regulatory T Cells in Tissue Pathophysiology and Metabolism
Campbell, Clarissa, Rudensky, Alexander · 2020 · Cell Metabolism
Bacterial virulence phenotypes of Escherichia coli and host susceptibility determine risk for urinary tract infections
Henry L. Schreiber, Matt S. Conover, Wen‐Chi Chou, Michael E. Hibbing, Abigail L. Manson, Karen Dodson, Thomas J. Hannan, Pacita L. Roberts, Ann E. Stapleton, Thomas M. Hooton et al. · 2017 · Science Translational Medicine
Gut Microbiota Modulation on Intestinal Mucosal Adaptive Immunity
Li Wang, Limeng Zhu, Song Qin · 2019 · Journal of Immunology Research
Deconstructing Mechanisms of Diet-Microbiome-Immune Interactions
Margaret Alexander, Peter James Turnbaugh · 2020 · Immunity
Gut microbiota and Hashimoto’s thyroiditis
Camilla Virili, Poupak Fallahi, Alessandro Antonelli, Salvatore Benvenga, Marco Centanni · 2018 · Reviews in Endocrine and Metabolic Disorders
Emerging concepts in intestinal immune control of obesity-related metabolic disease
Saad M. Khan, Helen Luck, Shawn Winer, Daniel A. Winer · 2021 · Nature Communications
Regulatory T Cell-Derived TGF-β1 Controls Multiple Checkpoints Governing Allergy and Autoimmunity
Jacob Turner, Emmanuel Stephen Victor, Sen Wang, Magali Noval Rivas, Azza Abdel-Gadir, Hani Harb, Ye Cui, Manoussa Fanny, Louis‐Marie Charbonnier, Jason Jun Hung Fong et al. · 2020 · Immunity
Identification and validation of a tumor-infiltrating Treg transcriptional signature conserved across species and tumor types
Angela M. Magnuson, Evgeny Kiner, Ayla Ergün, Jun Seok Park, Natasha Asinovski, Adriana Ortiz-Lopez, Aoife Kilcoyne, Elisa Paoluzzi-Tomada, Ralph Weissleder, Diane J. Mathis et al. · 2018 · Proceedings of the National Academy of Sciences
How bile acids and the microbiota interact to shape host immunity
Lee, Michael H., Nuccio, Sean-Paul, Mohanty, Ipsita, Hagey, Lee R., Dorrestein, Pieter C., Chu, Hiutung, Raffatellu, Manuela · 2024 · Nature Reviews Immunology
Epigenetic mechanisms regulating T-cell responses
Christian Schmidl, Michael Delacher, Jochen Huehn, Markus Feuerer · 2018 · Journal of Allergy and Clinical Immunology
Regulatory T cells in skin are uniquely poised to suppress profibrotic immune responses
Lokesh A. Kalekar, Jarish N. Cohen, Nicolas Prevel, Priscila Muñoz Sandoval, Anubhav N. Mathur, Joshua Michael Moreau, Margaret M. Lowe, Audrey Nosbaum, Paul J. Wolters, Anna K. Haemel et al. · 2019 · Science Immunology
Generation of RORγt+ Antigen-Specific T Regulatory 17 Cells from Foxp3+ Precursors in Autoimmunity
Kim, Byung-Seok, Lu, Huiping, Ichiyama, Kenji, Chen, Xiang, Zhang, Yi-Bing, Mistry, Nipun A., Tanaka, Kentaro, Lee, Young-hee, Nurieva, Roza, Zhang, Li et al. · 2017 · Cell Reports
The TNF Receptor Superfamily-NF-κB Axis Is Critical to Maintain Effector Regulatory T Cells in Lymphoid and Non-lymphoid Tissues
Ajithkumar Vasanthakumar, Yang Liao, Peggy P. Teh, María Fernanda Pascutti, Anna E. Oja, Alexandra L. Garnham, Renee Gloury, Jessica C. Tempany, Tom Sidwell, Eloy Cuadrado et al. · 2017 · Cell Reports
Role of probiotics and prebiotics in immunomodulation
Nour Yahfoufi, Jean‐François Mallet, Émilie A. Graham, Chantal Matar · 2018 · Current Opinion in Food Science
‘Layered immunity’ and the ‘neonatal window of opportunity’ – timed succession of non‐redundant phases to establish mucosal host–microbial homeostasis after birth
Mathias Walter Hornef, Natalia Torow · 2019 · Immunology
Small intestine vs. colon ecology and physiology: Why it matters in probiotic administration
Benjamin A. H. Jensen, Marc Heyndrickx, Daisy M.A.E. Jonkers, Alan R. Mackie, Sam Millet, Malwina Naghibi, Simone Isling Pærregaard, Bruno Pot, Delphine M. A. Saulnier, Christian Sina et al. · 2023 · Cell Reports Medicine
Gut Microbiome and Osteoporosis
Ding, Kai, Hua, Fei, Ding, Wenge · 2020 · Aging and disease
CD103hi Treg cells constrain lung fibrosis induced by CD103lo tissue-resident pathogenic CD4 T cells
Tomomi Ichikawa, Kiyoshi Hirahara, Kota Kokubo, Masahiro Kiuchi, Ami Aoki, Yuki Morimoto, Jin Kumagai, Atsushi Onodera, Naoko Mato, Damon John Tumes et al. · 2019 · Nature Immunology
Arresting microbiome development limits immune system maturation and resistance to infection in mice
Jean‐Bernard Lubin, Jamal Green, Sarah Maddux, Lidiya Denu, Tereza Duranova, Matthew R. Lanza, Meghan A. Wynosky-Dolfi, Julia N. Flores, Logan P. Grimes, Igor E. Brodsky et al. · 2023 · Cell Host & Microbe
The role of transcription factors in shaping regulatory T cell identity
Jorge Luis Trujillo-Ochoa, Majid Kazemian, Behdad Afzali · 2023 · Nature reviews. Immunology
Ten questions concerning the built environment and mental health
Andrew J. Hoisington, Kelly A. Stearns‐Yoder, Steven Schuldt, Cody J. Beemer, Juan Pedro Maestre, Kerry A. Kinney, Teodor T. Postolache, Christopher A. Lowry, Lisa A. Brenner · 2019 · Building and Environment
Comparing early life nutritional sources and human milk feeding practices: personalized and dynamic nutrition supports infant gut microbiome development and immune system maturation
Spencer R. Ames, Larisa C. Lotoski, Meghan B. Azad · 2023 · Gut Microbes
The gut ecosystem and immune tolerance
Tihong Shao, Ronald Hsu, Desiree L. Rafizadeh, Li Wang, Christopher L. Bowlus, Narendra Kumar, Jayshree Mishra, Suraj Timilsina, William M. Ridgway, Merrill Eric Gershwin et al. · 2023 · Journal of Autoimmunity
Host-Microbiota Interactions Shape Local and Systemic Inflammatory Diseases
Grigg, John B, Sonnenberg, Gregory F · 2017 · The Journal of Immunology
Talk to your gut: the oral-gut microbiome axis and its immunomodulatory role in the etiology of rheumatoid arthritis
Marines du Teil Espina, Giorgio Gabarrini, Hermie J. M. Harmsen, Johanna Westra, Arie Jan Van Winkelhoff, Jan Maarten van Dijl · 2018 · FEMS Microbiology Reviews
Microbial transmission in the social microbiome and host health and disease
Amar Sarkar, Cameron J.A. McInroy, Siobhán Harty, Aura Raulo, Neil G.O. Ibata, Mireia Valles‐Colomer, Katerina V.‐A. Johnson, Ilana Brito, Joseph Henrich, Elizabeth A. Archie et al. · 2024 · Cell
Arachidonic acid in health and disease with focus on hypertension and diabetes mellitus: A review
Undurti Narasimha Das · 2018 · Journal of Advanced Research
Regulatory T Cell Plasticity and Stability and Autoimmune Diseases
Runze Qiu, Liyu Zhou, Yuanjing Ma, Lingling Zhou, Tao Liang, Le Shi, Jun Long, Dongping Yuan · 2018 · Clinical Reviews in Allergy & Immunology
Regulatory T cells in the face of the intestinal microbiota
Ramanan, Deepshika, Pratama, Alvin, Zhu, Yangyang, Venezia, Olivia, Sassone-Corsi, Martina, Chowdhary, Kaitavjeet, Galván-Peña, Silvia, Sefik, Esen, Brown, Chrysothemis, Gélineau, Adélaïde et al. · 2023 · Nature Reviews Immunology
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Hanna, Bola S., Wang, Gang, Galván-Peña, Silvia, Mann, Alexander O., Ramirez, Ricardo N., Muñoz-Rojas, Andrés R., Smith, Kathleen, Wan, Min, Benoist, Christophe, Mathis, Diane · 2023 · Immunity
Transforming growth factor β: a master regulator of the gut microbiota and immune cell interactions
David Bauché, Julien C. Marie · 2017 · Clinical & Translational Immunology
T Cell Responses to the Microbiota
Ivaylo I. Ivanov, Timur Tuganbaev, Ashwin N. Skelly, Kenya Honda · 2022 · Annual Review of Immunology
Causal effects of the microbiota on immune-mediated diseases
June L. Round, Noah W. Palm · 2018 · Science Immunology
Antigen-specific regulatory T-cell responses to intestinal microbiota
Emilie V. Russler-Germain, Sunaina Rengarajan, C-S Hsieh · 2017 · Mucosal Immunology
Host immunomodulatory lipids created by symbionts from dietary amino acids
Sungwhan F. Oh, T. Praveena, Heebum Song, Ji‐Sun Yoo, Da-Jung Jung, Deniz Ertürk-Hasdemir, Yoon Soo Hwang, ChangWon C. Lee, Jérôme Le Nours, Hyunsoo Kim et al. · 2021 · Nature
Directed remodeling of the mouse gut microbiome inhibits the development of atherosclerosis
Poshen B. Chen, Audrey S. Black, Adam L. Sobel, Yannan Zhao, Purba Mukherjee, Bhuvan Molparia, Nina E. Moore, German R. Aleman Muench, Jiejun Wu, Weixuan Chen et al. · 2020 · Nature Biotechnology
The Influence of the Microbiome on Allergic Sensitization to Food
Catherine H. Plunkett, Cathryn Nagler‐Anderson · 2017 · The Journal of Immunology
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Pulavendran Sivasami, Cody M. Elkins, Pamela P. Diaz-Saldana, Kyndal L. Goss, Amy Chia-Ying Peng, Michael Hamersky, Jennifer Bae, Miaoer Xu, Brian P. Pollack, Edwin M. Horwitz et al. · 2023 · Immunity
A chemogenetic screen reveals that Trpv1-expressing neurons control regulatory T cells in the gut
Yangyang Zhu, Kimberly A. Meerschaert, Silvia Galván-Peña, Na‐Ryum Bin, Daping Yang, Himanish Basu, Ryo Kawamoto, Amre Shalaby, Stephen D. Liberles, Diane J. Mathis et al. · 2024 · Science
JunB regulates homeostasis and suppressive functions of effector regulatory T cells
Shin-ichi Koizumi, Daiki Sasaki, Tsung-han Hsieh, Naoyuki Taira, Nana Arakaki, Shinichi Yamasaki, Ke Wang, Shukla Sarkar, Hiroki Shirahata, Mio Miyagi et al. · 2018 · Nature Communications
Oleic acid restores suppressive defects in tissue-resident FOXP3 Tregs from patients with multiple sclerosis
Saige L. Pompura, Allon Wagner, Alexandra Kitz, Jacob M. Laperche, Nir Yosef, Margarita Dominguez‐Villar, David A. Hafler · 2020 · Journal of Clinical Investigation
Human retinoic acid–regulated CD161+ regulatory T cells support wound repair in intestinal mucosa
Povoleri, Giovanni A. M., Nova-Lamperti, Estefania, Scottà, Cristiano, Fanelli, Giorgia, Chen, Yun-Ching, Becker, Pablo D., Boardman, Dominic, Costantini, Benedetta, Romano, Marco, Pavlidis, Polychronis et al. · 2018 · Nature Immunology
Interleukin-33 activates regulatory T cells to suppress innate γδ T cell responses in the lung
Lucas Faustino, Jason W. Griffith, Rod A. Rahimi, Keshav Nepal, Daniel L. Hamilos, Josalyn L. Cho, Benjamin D. Medoff, James J. Moon, Dario A.A. Vignali, Andrew David Luster · 2020 · Nature Immunology
Diet modulates colonic T cell responses by regulating the expression of a Bacteroides thetaiotaomicron antigen
Marta M. Wegorzewska, Robert W. P. Glowacki, Samantha A. Hsieh, David L. Donermeyer, Christina A. Hickey, Stephen C. Horvath, Eric C. Martens, Thaddeus S. Stappenbeck, Paul M. Allen · 2019 · Science Immunology
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SGK1 Governs the Reciprocal Development of Th17 and Regulatory T Cells
Chuan Wu, Zuojia Chen, Sheng Xiao, Theresa Thalhamer, Asaf Madi, Timothy M. Han, Vijay Kumar Kuchroo · 2018 · Cell Reports
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Stephanie A. Bora, Mary J. Kennett, Philip B. W. Smith, Andrew D. Patterson, Margherita T. Cantorna · 2018 · Frontiers in Immunology
Regulatory T Cell Development in the Thymus
David L. Owen, Louisa E. Sjaastad, Michael A. Farrar · 2019 · The Journal of Immunology
An intact gut microbiome protects genetically predisposed mice against leukemia
Vicente-Dueñas, Carolina, Janssen, Stefan, Oldenburg, Marina, Auer, Franziska, González-Herrero, Inés, Casado-García, Ana, Isidro-Hernández, Marta, Raboso-Gallego, Javier, Westhoff, Philipp, Pandyra, Aleksandra A. et al. · 2020 · Blood
An evolutionary perspective on the systems of adaptive immunity
Viktor Müller, Rob J. de Boer, Sebastian Bonhoeffer, Eörs Szathmáry · 2017 · Biological reviews/Biological reviews of the Cambridge Philosophical Society
Defined microbiota transplant restores Th17/RORγt + regulatory T cell balance in mice colonized with inflammatory bowel disease microbiotas
Graham J. Britton, Eduardo J. Contijoch, Matthew P. Spindler, Varun Aggarwala, Belgin Dogan, Gerold Bongers, Lani San Mateo, Andrew E. Baltus, Anuk Das, Dirk Gevers et al. · 2020 · Proceedings of the National Academy of Sciences
Microbiota-dependent activation of CD4 + T cells induces CTLA-4 blockade–associated colitis via Fcγ receptors
Bernard C. Lo, Ilona Kryczek, Jiali Yu, Linda Vatan, Roberta Caruso, Masanori Matsumoto, Yosuke Sato, Michael H. Shaw, Naohiro Inohara, Yuying Xie et al. · 2024 · Science
Potential anti-tumor effects of regulatory T cells in the tumor microenvironment: a review
Li, Yu, Zhang, Cangang, Jiang, Aimin, Lin, Anqi, Liu, Zaoqu, Cheng, Xiangshu, Wang, Wanting, Cheng, Quan, Zhang, Jian, Wei, Ting et al. · 2024 · Journal of Translational Medicine
Clinical Effect of IRT-5 Probiotics on Immune Modulation of Autoimmunity or Alloimmunity in the Eye
Jaeyoung Kim, Se Hyun Choi, Yu Kim, Hyun Jeong Jeong, Jin Ju Ryu, Hyun Jung Lee, Tae Kim, Sin‐Hyeog Im, Joo Youn Oh, Mee Kim · 2017 · Nutrients
Gut microbiome in chronic rheumatic and inflammatory bowel diseases: Similarities and differences
Fatouma Salem, Nadège Kindt, Julian Roberto Marchesi, Patrick Netter, Anthony Lopez, Tunay Kökten, Silvio Danese, Jean‐Yves Jouzeau, Laurent Peyrin‐Biroulet, David Moulin · 2019 · United European Gastroenterology Journal
Programmed and environmental determinants driving neonatal mucosal immune development
Natalia Torow, Timothy Wesley Hand, Mathias Walter Hornef · 2023 · Immunity
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Catalina Cosovanu, Christian Neumann · 2020 · Frontiers in Immunology
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Xiao Hu, Xikui Liu, Jacques Moisan, Yahong Wang, Charles A. Lesch, Chauncey J. Spooner, Rodney W. Morgan, Elizabeth M. Zawidzka, David R. Mertz, Dick Bousley et al. · 2016 · OncoImmunology
Singular role for T-BET + CXCR3 + regulatory T cells in protection from autoimmune diabetes
Tze Guan Tan, Diane J. Mathis, Christophe O. Benoist · 2016 · Proceedings of the National Academy of Sciences
The effect of diet on hypertensive pathology: is there a link via gut microbiota-driven immunometabolism?
Hamdi A. Jama, Anna Louise Beale, Waled Shihata, Francine Z. Marques · 2019 · Cardiovascular Research
RORγt, a multitask nuclear receptor at mucosal surfaces
Gérard Eberl · 2016 · Mucosal Immunology
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Brianna R. Traxinger, Laura E. Richert-Spuhler, Jennifer M. Lund · 2021 · Mucosal Immunology
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Katherine Z. Sanidad, Stephanie L. Rager, Hannah C. Carrow, Aparna Ananthanarayanan, Ryann Callaghan, Lucy R. Hart, Tingting Li, Purnima Ravisankar, Julia A. Brown, Mohammed Amir et al. · 2024 · Science Immunology
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Siobhan Crittenden, Marie Goepp, Jolinda Pollock, Calum T. Robb, Danielle J. Smyth, You Zhou, Robert Andrews, Victoria J. Tyrrell, Konstantinos Gkikas, Alexander Adima et al. · 2021 · Science Advances
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Philip P. Ahern, Kevin Joseph Maloy · 2019 · Immunology
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Emmanuel Stephen Victor, Elena Crestani, Talal A. Chatila · 2020 · Immunity
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