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Proinflammatory Effect of Carbon-Based Nanomaterials: In Vitro Study on Stimulation of Inflammasome NLRP3 via Destabilisation of Lysosomes

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A potential new pathway for heparin treatment of sepsis-induced lung injury: inhibition of pulmonary endothelial cell pyroptosis by blocking hMGB1-LPS-induced caspase-11 activation

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Inflammasome Activation in Response to Intracellular Protozoan Parasites

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Galectin-3 promotes noncanonical inflammasome activation through intracellular binding to lipopolysaccharide glycans

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Structural library and visualization of endogenously oxidized phosphatidylcholines using mass spectrometry-based techniques

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Spotlight on NLRP3 Inflammasome: Role in Pathogenesis and Therapies of Atherosclerosis

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Caspase-11 Non-Canonical Inflammasome: Emerging Activator and Regulator of Infection-Mediated Inflammatory Responses

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Targeting oxidized phospholipids by AAV-based gene therapy in mice with established hepatic steatosis prevents progression to fibrosis

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An update on the NLRP3 inflammasome and influenza: the road to redemption or perdition?

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Sirt6-induced autophagy restricted TREM-1-mediated pyroptosis in ox-LDL-treated endothelial cells: relevance to prognostication of patients with acute myocardial infarction

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Pyroptosis in Steatohepatitis and Liver Diseases

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Focus on the Mechanisms and Functions of Pyroptosis, Inflammasomes, and Inflammatory Caspases in Infectious Diseases

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Hyperoxidation of ether-linked phospholipids accelerates neutrophil extracellular trap formation

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Pyroptosis and Its Role in SARS-CoV-2 Infection

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Unraveling the role of NLRP3 inflammasome in allergic inflammation: implications for novel therapies

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Delaying pyroptosis with an AI-screened gasdermin D pore blocker mitigates inflammatory response

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Targeting pyroptosis to regulate ischemic stroke injury: Molecular mechanisms and preclinical evidences

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A "trained immunity" inducer-adjuvanted nanovaccine reverses the growth of established tumors in mice

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IAPs and Cell Death

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Gasdermin D Flashes an Exit Signal for IL-1

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Evolution-inspired redesign of the LPS receptor caspase-4 into an interleukin-1β–converting enzyme

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Host inflammasome defense mechanisms and bacterial pathogen evasion strategies

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Lipids that directly regulate innate immune signal transduction

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Lipid-protein interactions regulating the canonical and the non-canonical NLRP3 inflammasome

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A Lipid Perspective on Regulated Pyroptosis

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Oxidized Phospholipids in Healthy and Diseased Lung Endothelium

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Systemic dysregulation of the gut microenvironment plays a pivotal role in the onset and progression of inflammatory bowel disease

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Biological mechanisms and therapeutic relevance of the gasdermin family

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Chronic Intestinal Inflammation Suppresses Brain Activity by Inducing Neuroinflammation in Mice

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Cytokine-armed pyroptosis induces antitumor immunity against diverse types of tumors

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Pyroptotic cell corpses are crowned with F-actin-rich filopodia that engage CLEC9A signaling in incoming dendritic cells

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Inflammasomes in dendritic cells: Friend or foe?

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Approaching Neutrophil Pyroptosis

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Mini-Review: GSDME-Mediated Pyroptosis in Diabetic Nephropathy

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The Brucella effector protein TcpB induces degradation of inflammatory caspases and thereby subverts non-canonical inflammasome activation in macrophages

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The Potential of NLRP3 Inflammasome as a Therapeutic Target in Neurological Diseases

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Lethal and Non-Lethal Functions of Caspases in the DNA Damage Response

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NLRP3, the inflammasome and COVID-19 infection

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The noncanonical inflammasome-induced pyroptosis and septic shock

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How Membrane Phospholipids Containing Long-Chain Polyunsaturated Fatty Acids and Their Oxidation Products Orchestrate Lipid Raft Dynamics to Control Inflammation

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Defying Death: The (W)hole Truth about the Fate of GSDMD Pores

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Harnessing the Complete Repertoire of Conventional Dendritic Cell Functions for Cancer Immunotherapy

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Hierarchical cell-type-specific functions of caspase-11 in LPS shock and antibacterial host defense

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Molecular and structural aspects of gasdermin family pores and insights into gasdermin-elicited programmed cell death

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Pyroptosis as a candidate therapeutic target for Alzheimer’s disease

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Pyroptosis: A spoiler of peaceful coexistence between cells in degenerative bone and joint diseases

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IL-1β+ macrophages and the control of pathogenic inflammation in cancer

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Tissue Damage Signaling Is a Prerequisite for Protective Neutrophil Recruitment to Microbial Infection in Zebrafish

Huang, C., & Niethammer, P. (2018) · Immunity · doi:10.1016/j.immuni.2018.04.020 · Cited by 36

Mutual Interplay of Host Immune System and Gut Microbiota in the Immunopathology of Atherosclerosis

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Arf1 Ablation in Colorectal Cancer Cells Activates a Super Signal Complex in DC to Enhance Anti‐Tumor Immunity

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NLRP1 Inflammasome Activation in Keratinocytes: Increasing Evidence of Important Roles in Inflammatory Skin Diseases and Immunity

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The Phagocyte Oxidase Controls Tolerance to Mycobacterium tuberculosis Infection

Olive, A. J., Smith, C. M., Kiritsy, M. C., & Sassetti, C. M. (2018) · The Journal of Immunology · doi:10.4049/jimmunol.1800202 · Cited by 35

Stearoyl Lysophosphatidylcholine Inhibits Endotoxin-Induced Caspase-11 Activation

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The role of oxidized phospholipids in the development of disease

Nie, J. S., Yang, J., Wei, Y., & Wei, X. (2020) · Molecular Aspects of Medicine · doi:10.1016/j.mam.2020.100909 · Cited by 33

Diverse Control Mechanisms of the Interleukin-1 Cytokine Family

Evavold, C. L., & Kagan, J. C. (2022) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2022.910983 · Cited by 34

IL-1β and Allergy: Focusing on Its Role in Allergic Rhinitis

Wang, H., Wei, S., Song, X., Wang, Y., Zhang, W., Ren, C., Mou, Y., & Song, X. (2023) · Mediators of Inflammation · doi:10.1155/2023/1265449 · Cited by 34

Pyroptosis: A road to next-generation cancer immunotherapy

Fang, Y., Tang, Y., & Huang, B. (2023) · Seminars in Immunology · doi:10.1016/j.smim.2023.101782 · Cited by 34

Cyclopentenone Prostaglandins and Structurally Related Oxidized Lipid Species Instigate and Share Distinct Pro- and Anti-inflammatory Pathways

Muri, J., Feng, Q., Wolleb, H., Shamshiev, A. T., Ebner, C., Tortola, L., Brož, P., Carreira, E. M., & Köpf, M. (2020) · Cell Reports · doi:10.1016/j.celrep.2020.03.019 · Cited by 34

Biphasic JNK signaling reveals distinct MAP3K complexes licensing inflammasome formation and pyroptosis

Bradfield, C. J., Liang, J. J., Ernst, O., John, S. P., Sun, J., Ganesan, S., de Jesus, A. A., Bryant, C. E., Goldbach-Mansky, R., & Fraser, I. D. C. (2023) · Cell Death & Differentiation · doi:10.1038/s41418-022-01106-9 · Cited by 33

Intrinsic coating morphology modulates acute drug transfer in drug-coated balloon therapy

Chang, G. H., Azar, D., Lyle, C., Chitalia, V. C., Shazly, T. M., & Kolachalama, V. B. (2019) · Scientific Reports · doi:10.1038/s41598-019-43095-9 · Cited by 33

Shiga toxin suppresses noncanonical inflammasome responses to cytosolic LPS

Havira, M. S., Ta, A., Kumari, P., Wang, C., Russo, A. J., Ruan, J., Rathinam, V. A. K., & Vanaja, S. K. (2020) · Science Immunology · doi:10.1126/sciimmunol.abc0217 · Cited by 33

Identification of Key Pyroptosis-Related Genes and Distinct Pyroptosis-Related Clusters in Periodontitis

Ning, W., Acharya, A., Li, S., Schmalz, G., & Huang, S. (2022) · Frontiers in Immunology · doi:10.3389/fimmu.2022.862049 · Cited by 33

Mesenchymal Stromal Cells Directly Promote Inflammation by Canonical NLRP3 and Non-canonical Caspase-11 Inflammasomes

Chen, Y., Qin, X., An, Q., Yi, J., Feng, F., Yin, D., An, N., Liu, Z., Weng, L., Chen, S., et al. (2018) · EBioMedicine · doi:10.1016/j.ebiom.2018.05.023 · Cited by 33

Unconventional protein secretion by gasdermin pores

Brož, P. (2023) · Seminars in Immunology · doi:10.1016/j.smim.2023.101811 · Cited by 32

Controlling pyroptosis through post-translational modifications of gasdermin D

Zhang, N., & Xu, D. (2025) · Developmental Cell · doi:10.1016/j.devcel.2025.02.005 · Cited by 33

Guanylate-binding proteins at the crossroad of noncanonical inflammasome activation during bacterial infections

Gomes, M. T. R., Cerqueira, D. M., Guimarães, E. S., Campos, P. C., & Oliveira, S. C. (2019) · Journal of Leukocyte Biology · doi:10.1002/jlb.4mr0119-013r · Cited by 32

Prophylactic and therapeutic insights into trained immunity: A renewed concept of innate immune memory

Bindu, S., Dandapat, S., Manikandan, R., Dinesh, M., Anbazhagan, S., Pashupathi, M., Dhawan, M. K., Tiwari, R., Bilal, M., Emran, T. B., et al. (2022) · Human Vaccines & Immunotherapeutics · doi:10.1080/21645515.2022.2040238 · Cited by 32

New insights into Gasdermin D pore formation

Kappelhoff, S., Margheritis, E. G., & Cosentino, K. (2024) · Biochemical Society Transactions · doi:10.1042/bst20230549 · Cited by 31

Evaluation of air oxidized PAPC: A multi laboratory study by LC-MS/MS

Ni, Z., Sousa, B. C., Colombo, S., Afonso, C. B., Melo, T., Pitt, A. R., Spickett, C. M., Domingues, P. M., Domingues, M. R., Fedorova, M., et al. (2019) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2019.06.013 · Cited by 31

Lysozyme elicits pain during nerve injury by neuronal Toll-like receptor 4 activation and has therapeutic potential in neuropathic pain

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Induction of ASC pyroptosis requires gasdermin D or caspase-1/11-dependent mediators and IFNβ from pyroptotic macrophages

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Non-canonical inflammasome activation mediates the adjuvanticity of nanoparticles

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Inflammasomes in Myeloid Cells: Warriors Within

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Electrophiles against (Skin) Diseases: More Than Nrf2

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Membrane Dynamics and Cation Handling in Ferroptosis

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