An endogenous caspase-11 ligand elicits interleukin-1 release from living dendritic cells

Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death

Shi, J., Zhao, Y., Wang, K., Shi, X., Wang, Y., Huang, H., Zhuang, Y., Cai, T., Wang, F., & Shao, F. (2015) · Nature · doi:10.1038/nature15514 · Cited by 6,659

The Inflammasome

Martinon, F., Burns, K., & Tschopp, J. (2002) · Molecular Cell · doi:10.1016/s1097-2765(02)00599-3 · Cited by 6,066

Caspase-11 cleaves gasdermin D for non-canonical inflammasome signalling

Kayagaki, N., Stowe, I. B., Lee, B. L., O’Rourke, K., Anderson, K., Warming, S., Cuellar, T., Haley, B., Roose-Girma, M., Phung, Q. T., et al. (2015) · Nature · doi:10.1038/nature15541 · Cited by 3,686

Inflammatory caspases are innate immune receptors for intracellular LPS

Shi, J., Zhao, Y., Wang, Y., Gao, W., Ding, J., Li, P., Hu, L., & Shao, F. (2014) · Nature · doi:10.1038/nature13683 · Cited by 2,285

Control of adaptive immunity by the innate immune system

Iwasaki, A., & Medzhitov, R. (2015) · Nature Immunology · doi:10.1038/ni.3123 · Cited by 2,160

How dying cells alert the immune system to danger

Kono, H., & Rock, K. L. (2008) · Nature Reviews Immunology · doi:10.1038/nri2215 · Cited by 1,737

Noncanonical Inflammasome Activation by Intracellular LPS Independent of TLR4

Kayagaki, N., Wong, M. T., Stowe, I. B., Ramani, S. R., Gonzalez, L. C., Akashi‐Takamura, S., Miyake, K., Zhang, J., Lee, W. P., Muszyński, A., et al. (2013) · Science · doi:10.1126/science.1240248 · Cited by 1,545

The IL-1 family: regulators of immunity

Sims, J. E., & Smith, D. E. (2010) · Nature reviews. Immunology · doi:10.1038/nri2691 · Cited by 1,459

Identification of Oxidative Stress and Toll-like Receptor 4 Signaling as a Key Pathway of Acute Lung Injury

Imai, Y., Kuba, K., Neely, G. G., Yaghubian-Malhami, R., Perkmann, T., van Loo, G., Ermolaeva, M., Veldhuizen, R., Leung, Y. H. C., Wang, H., et al. (2008) · Cell · doi:10.1016/j.cell.2008.02.043 · Cited by 1,356

Pyroptotic cell death defends against intracellular pathogens

Jorgensen, I., & Miao, E. A. (2015) · Immunological Reviews · doi:10.1111/imr.12287 · Cited by 1,021

Regulation of Synovial γδ T Cell Ligand Expression by Mitochondrial Reactive Oxygen Species and Gasdermin-D

Collins, C. C., Hahn, P., Jiang, Z., Fitzgerald, K. A., Xiao, T. S., & Budd, R. C. (2023) · The Journal of Immunology · doi:10.4049/jimmunol.2101166 · Cited by 2

Pyroptosis: Physiological roles in viral infectionPreprint

Durán, N., & Fávaro, W. J. (2020) · arXiv (Cornell University) · doi:10.48550/arxiv.2006.15777 · Cited by 2

Correction of age-associated defects in dendritic cell functions enables CD4 + T cells to eradicate tumors in the elderlyPreprint

Zhivaki, D., Borriello, F., Kennedy, S. N., Evavold, C. L., Bahleda, K. M., Chapman, K. L., Zanoni, I., & Kagan, J. C. (2022) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2022.11.08.515695 · Cited by 2

Molecular signaling of inflammatory responses in macrophages

Yi, Y. (2022) · Elsevier eBooks · doi:10.1016/b978-0-12-822368-0.00005-0 · Cited by 1

Activation of GSDME by Lithospermum erythrorhizon drives pyroptotic cell death

Wang, S., Liu, Z., Guo, J., Li, Y., Zhang, Y., Yang, M., Niu, G., & Ma, W. (2023) · Journal of Traditional Chinese Medical Sciences · doi:10.1016/j.jtcms.2023.06.011 · Cited by 1

Targeting the NLRP3 inflammasome: Pharmacological mechanisms for the treatment of dry eye disease

Gong, J., Du, T., Ding, G., Gao, T., Hao, Z., Li, M., Wang, Z., Li, Y., Wang, X., & Zhang, C. (2025) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2025.178104 · Cited by 1

Rab43 mitigates the inflammatory response in acute lung injury via MyD88 ubiquitination

Wang, Y., Liu, X., Zhu, Z., Wu, D., Chen, Y., Gong, D., Wu, P., Qian, H., He, B., & Wang, G. (2026) · Scientific Reports · doi:10.1038/s41598-026-35187-0 · Cited by 1

Combinatorial Design of Fatty Acid-Incorporated Plasmid Lipid Nanoparticles Drives Dendritic Cell Hyperactivation for Enhanced Cancer Immunotherapy

Li, Z., Jia, F., Wang, H., Lan, Z., Chen, H., & Ma, M. (2026) · ACS Nano · doi:10.1021/acsnano.6c01946 · Cited by 1

A glycan-based adjuvant expands the breadth and duration of protection of mRNA-based vaccines

Jena, K. K., Qu, P., Baracco, L., Saghaei, S., Keerti, K., Allahyari, Z., Boehmer, D. F. R., Mitchell, M., Dillen, C. A., Li, H., et al. (2026) · Nature Immunology · doi:10.1038/s41590-026-02517-3 · Cited by 1

Pathways of Protein Secretion in Prokaryotes and Eukaryotes: Molecular Mechanisms, Biological Functions, and Therapeutic Opportunities

Yang, Q., Shi, J., Xu, L., Zhao, G., Chen, Y., Cheng, L., Li, X., 孙志刚, & Huang, S. (2026) · MedComm · doi:10.1002/mco2.70798 · Cited by 1

Simultaneous Detection of Cellular Viability and Interleukin-1β Secretion from Single Cells by ELISpot

Conos, S. A., Lindqvist, L., & Vince, J. E. (2017) · Methods in molecular biology · doi:10.1007/978-1-4939-7519-8_15 · Cited by 1

Inflammasome formation and triggers

Hafner‐Bratkovič, I. (2022) · Elsevier eBooks · doi:10.1016/b978-0-323-91802-2.00006-2 · Cited by 1

Zebrafish earns its stripes for in vivo ASC speck dynamics

Bezbradica, J. S., & Schroder, K. (2017) · The Journal of Cell Biology · doi:10.1083/jcb.201708002 · Cited by 1

Molecular mechanism of pyroptosis and its role in cancer

Wu, S., Wong, P., Chen, Y., Su, L., & Qiu, X. (2020) · Scientia Sinica Vitae · doi:10.1360/ssv-2020-0065 · Cited by 1

Role of Inflammation and Inflammasomes in Bone Pathophysiology

Mbalaviele, G., & Abu‐Amer, Y. (2019) · Elsevier eBooks · doi:10.1016/b978-0-12-801238-3.11167-5 · Cited by 1

Hidrogenación catalítica de aceites vegetales

Gutiérrez-Ortiz, J. I., González, C. A. L., & González-Velasco, J. R. (1997) · Alimentación, equipos y tecnología · Cited by 1

Cytoplasmic Sensing in Innate Immunity

Akhade, A. S., & Subramanian, N. (2022) · Elsevier eBooks · doi:10.1016/b978-0-12-821618-7.00012-2 · Cited by 1

Faculty Opinions recommendation of The NLRP6 Inflammasome Recognizes Lipoteichoic Acid and Regulates Gram-Positive Pathogen Infection.

Triantafilou, K. (2019) · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature · doi:10.3410/f.734357156.793560837 · Cited by 1

Chronic sensing of host-derived lipids is an all-in-one signal that primes and activates NLRP3Preprint

Dufies, O., Gioia, M. D., Spreafico, R., Tan, P. J., Springstead, J. R., Prell, S. A., Case, J., Gao, C., Wei, K., Wu, H., et al. (2025) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2025.10.29.685328 · Cited by 1

Fibrogenèse pulmonaire induite par la toxicité de la bléomycine et son point de départ sous-pleural

Burgy, O. (2016) · theses.fr (ABES) · doi:10.70675/1a8954ecz5e2az462cza41dz21af6356beb5

Jonathan Kagan: A cell biologist’s view of immunity

O’Donnell, M. A. (2017) · The Journal of Cell Biology · doi:10.1083/jcb.201705065

Papel do inflamassoma na imunopatogênese da malária grave.

dos Reis, A. S. (2017) · Digital Library of Theses and Dissertations (Universidade de São Paulo) · doi:10.11606/t.42.2017.tde-14072017-170034

Tick Saliva and Microbial Effector Molecules

Shaw, D. K., McClure, E. E., Kotsyfakis, M., & Pedra, J. H. F. (2017) · Elsevier eBooks · doi:10.1016/b978-0-12-805360-7.00010-1

Inflammasome regulation and activation in the intestinal epithelium

Lei, A. (2017) · Oxford University Research Archive (ORA) (University of Oxford) · doi:10.5287/ora-mzngoy5ob

Production and Characterization of Synthetic ErbB2 Virosomes for Vaccination Against Breast Cancer

Stafford, A. G. (2018) · Digital Access to Scholarship at Harvard (DASH) (Harvard University)

Caracterización del receptor purinérgico P2X7 y el inflamasoma LNRP3 en la respuesta inflamatoria inducida por péptidos antimicrobianos e infecciones

García, M., & José, J. C. M. S. (2018) · LA Referencia (Red Federada de Repositorios Institucionales de Publicaciones Científicas)

The Phagocyte Oxidase Controls Tolerance to Mycobacterium tuberculosis infectionPreprint

Olive, A. J., Smith, C. S., Kiritsy, M. C., & Sassetti, C. M. (2017) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/232777

Etude de l'impact fonctionnel des modifications post-traductionnelles dans l'activation de l'inflammasome NLRP3

Groslambert, M. (2019) · theses.fr (ABES) · doi:10.70675/7ec36fdaz7c33z4ac3z8f3azf6a7d1320f06

Mecanismos moleculares envolvidos na ativação do inflamassoma NAIP/NLRC4

Branco, L. M. (2019) · Digital Library of Theses and Dissertations (Universidade de São Paulo) · doi:10.11606/t.42.2019.tde-16122019-120656

STING Engages Distinct Antiviral Mechanisms to Restrict RNA Virus and DNA Virus Replication

Franz, K. M. (2018) · Digital Access to Scholarship at Harvard (DASH) (Harvard University)

Advanced Geometric Analyses in Vascular Disease and Interventions

Azar, D. A. (2020) · Scholar Commons (University of South Carolina)

Ativação de macrófagos M1/M2 pela eferocitose de células apoptóticas infectadas

Salina, A. C. G. (2020) · Digital Library of Theses and Dissertations (Universidade de São Paulo) · doi:10.11606/t.17.2020.tde-25082020-090635

Perbandingan hukum perdata / oleh R. Soeroso

Soeroso, R. (1993)

Faculty Opinions recommendation of Human caspase-4 detects tetra-acylated LPS and cytosolic Francisella and functions differently from murine caspase-11.

Weiss, J. P. (2018) · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature · doi:10.3410/f.732498116.793545009

Faculty Opinions recommendation of Tissue damage signaling is a prerequisite for protective neutrophil recruitment to microbial infection in zebrafish.

Parkos, C. A. (2018) · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature · doi:10.3410/f.733233012.793553262

Faculty Opinions recommendation of Caspase-11 promotes allergic airway inflammation.

Keegan, A. D., & Chapoval, S. P. (2020) · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature · doi:10.3410/f.737440793.793571904

Inflamasoma NLRP-3: blanco de estudio en el desarrollo de la epilepsia

Universidad de Guadalajara, D. D. B. C. Y. M., Pardo‐Peña, K., Martínez-Gallegos, S. M., Noriega-Ruiz, M. A., & Vargas, F. V. V. (2022) · e-CUCBA · doi:10.32870/ecucba.vi18.249

Cellular signaling, molecular activation, and regulation of the noncanonical inflammasome

Dorfleutner, A., & Stehlik, C. (2022) · Elsevier eBooks · doi:10.1016/b978-0-323-91802-2.00028-1

Regulation of pyroptosis by inflammasomes

Angosto-Bazarra, D. (2022) · Elsevier eBooks · doi:10.1016/b978-0-323-91802-2.00026-8

Regulation of neutrophil NETosis by inflammasome

Hogg, A. J., Barlow, J. L., & Boucher, D. (2022) · Elsevier eBooks · doi:10.1016/b978-0-323-91802-2.00036-0

Autophagy and the inflammasome

Biasizzo, M., & Kopitar‐Jerala, N. (2022) · Elsevier eBooks · doi:10.1016/b978-0-323-91802-2.00011-6

Innate immune responses in COVID-19

Jacotot, E. D., Talamini, L., Bonam, S. R., Vieira, A. T., Frémeaux‐Bacchi, V., Radic, M. Z., Dragon‐Durey, M., Lozano, J. M., Saia, R. S., & Muller, S. (2023) · Elsevier eBooks · doi:10.1016/b978-0-443-18566-3.00041-4

Importância do inflamassoma no desenvolvimento das formas graves de COVID-19 em pacientes e em modelo experimental murino

Rodrigues, T. S. (2022) · Digital Library of Theses and Dissertations (Universidade de São Paulo) · doi:10.11606/t.17.2022.tde-10042023-161658

Advances in NLRP3 Inflammatory Vesicles and Insulin Resistance

周, 芸. (2023) · Advances in Clinical Medicine · doi:10.12677/acm.2023.1361292

Régulation immunométabolique des cellules myé-loïdes dans le développement du glioblastome : Étude des effets du lactate sur les cellules myéloïdes et du rôle de l'inflam-masome dans le développement du glioblastome

Lillo, S. (2023) · theses.fr (ABES) · doi:10.70675/49be81c2z656fz400dzbc64z391cf8330a65

L'α-enolase : un nouvel acteur dans l'activation de l'inflammasome NLRP3

Gámez, M. P. (2020) · theses.fr (ABES) · doi:10.70675/7256bd0dz0a0az448dzbfbfze20e35077958

Prevalence Around Inflammatory Caspases in Urinary Tract Infections, Review

Nisha, N., Sharma, D. C., Sharma, R. D., & Tomar, J. (2024) · Biosciences Biotechnology Research Asia · doi:10.13005/bbra/3308

NLRP3 inflammasome: significance and potential therapeutic targets to advance solid organ transplantation

Karsalari, P. D., Asnaashari, K., & Rezaei, N. (2025) · Expert Opinion on Therapeutic Targets · doi:10.1080/14728222.2025.2500425

Inflammasomes and DNA Damage Orchestrate Divergent Pyroptotic Fates in NeutrophilsPreprint

Singhal, A., Awasthi, N., Mondal, P. S., Singh, N. C., Guru, R., Chandra, T., Mitra, K., Dikshit, M., & Kumar, S. (2025) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2025.09.03.673694

Dissecting antimicrobial logic: species-specific strategies for intracellular pathogen defense

Bryson, B. D. (2025) · mSphere · doi:10.1128/msphere.00091-25

Additional file 4 of Evolutionary analyses of the gasdermin family suggest conserved roles in infection response despite loss of pore-forming functionality

Angosto-Bazarra, D., Alarcón‐Vila, C., Hurtado‐Navarro, L., Baños, M. C., Rivers‐Auty, J., & Pelegrı́n, P. (2022) · Figshare · doi:10.6084/m9.figshare.18070867

Additional file 5 of Evolutionary analyses of the gasdermin family suggest conserved roles in infection response despite loss of pore-forming functionality

Angosto-Bazarra, D., Alarcón‐Vila, C., Hurtado‐Navarro, L., Baños, M. C., Rivers‐Auty, J., & Pelegrı́n, P. (2022) · Figshare · doi:10.6084/m9.figshare.18070873

Additional file 1 of AIBP controls TLR4 inflammarafts and mitochondrial dysfunction in a mouse model of Alzheimer’s disease

Kim, Y. S., Choi, S.-H., Kim, K.-Y., Pelaez, J. M. N., Perkins, G. A., Choi, S., Kim, J., Nazarenkov, N., Rissman, R. A., Ju, W.-K., et al. (2024) · Figshare · doi:10.6084/m9.figshare.27129329

Additional file 1 of Evolutionary analyses of the gasdermin family suggest conserved roles in infection response despite loss of pore-forming functionality

Angosto-Bazarra, D., Alarcón‐Vila, C., Hurtado‐Navarro, L., Baños, M. C., Rivers‐Auty, J., & Pelegrı́n, P. (2022) · Figshare · doi:10.6084/m9.figshare.18070858

Additional file 8 of Evolutionary analyses of the gasdermin family suggest conserved roles in infection response despite loss of pore-forming functionality

Angosto-Bazarra, D., Alarcón‐Vila, C., Hurtado‐Navarro, L., Baños, M. C., Rivers‐Auty, J., & Pelegrı́n, P. (2022) · Figshare · doi:10.6084/m9.figshare.18070882

The role of canonical and non-canonical inflammasomes in a model of oxidative stress-induced retinal degeneration

Silke, E. (2024) · Trinity's Access to Research Output (TARA) (Trinity College Dublin)

On Self and Nonself A Case Study of the Cytosolic LPS Sensor Caspase-11

Cao, A. B. (2025) · Digital Access to Scholarship at Harvard (DASH) (Harvard University)

Pyroptosis-inducing nanomedicines: A dual-mode therapeutic framework for apoptosis-resistant lung cancer

Abuhassan, Q., Oriquat, G., Roopashree, R., Nayak, P. P., Sudhakar, T., Sharma, V., Chauhan, A. S., & Aliev, M. A. (2026) · Tissue and Cell · doi:10.1016/j.tice.2026.103361

oxPAPC ‐Mediated lncRNA CYP1B1 ‐ AS1 From Dendritic Cells Accelerates Atherosclerosis

Chen, Y., Ni, L., Ke, C., He, Y., Huang, Y., Lu, S., Zhao, Y., Ge, J., Shi, B., & Wang, Z. (2026) · Journal of Cellular and Molecular Medicine · doi:10.1111/jcmm.71066

Toxoplasma gondii effector MAF1 blocks mouse AIM2 inflammasome activation by inhibiting mtDNA release

Zhao, X.-Y., Holness, N. K., Lempke, S. L., Pernas, L. F., Newman, L. E., & Ewald, S. E. (2026) · The Journal of Immunology · doi:10.1093/jimmun/vkaf360

A Biomimetic Nanovesicle‐Based Synthetic Vaccine Platform Through Co‐Anchoring Oxidized Phospholipid and CpG for Rejuvenating Antitumor Immunity in Aged Mice

Miao, F., Lu, J., Zhao, Y., Wang, W., Zhang, T., Liu, J., Zhang, X., Wu, L., Yan, H., Wang, R., et al. (2026) · Angewandte Chemie · doi:10.1002/ange.202522249

Implication de l'inflammasome NLRP3 dans la sécrétion non conventionnelle de la protéine FADD

Mouasni, S. (2018) · theses.fr (ABES) · doi:10.70675/8623f190zbb94z44b7z8b70zd93fa9be484d

Le rôle des Guanylate Binding Proteins dans l’immunité cytosolique du macrophage : bactériolyse et morts cellulaires inflammasome-dépendant et indépendant

Wallet, P. (2017) · theses.fr (ABES) · doi:10.70675/81efce18ze9faz40cfzab53z6bfc2b336690

Detection of cytosolic LPS : a genome-wide CRISPR/Cas9 screen identifies IRF2 as a regulator of the non-canonical inflammasome caspase-4

Benaoudia, S. (2018) · theses.fr (ABES) · doi:10.70675/88572e41za0f2z46b3zbaecz6d4664253112

L'action ambivalente de l'agent anti-cancéreux 5-Fluorouracile sur les cellules myéloïdes immunosuppressives sous contrôle de l'acide docosahexaénoïque : Rôle de l'inflammasome NLRP3 et de la voie JNK dans la sécrétion de l'IL-1beta

Dumont, A. (2018) · theses.fr (ABES) · doi:10.70675/01e0a564z8829z4bebz978bz17aa7a43cb26

Etude de la production d'IL-1Beta induite par les cristaux d'urate monosodique et pyrophosphate de calcium

Renaudin, F. (2019) · theses.fr (ABES) · doi:10.70675/10d49546z0c10z44cbzac94z20a00dfad246

Molecular and cellular bases of systemic autoinflammatory disorders including Adult-onset Still’s disease

Assrawi, E. (2019) · theses.fr (ABES) · doi:10.70675/82f530d5z0154z474cz9746z470b6a42c9e0

Physiopathologie des maladies auto-inflammatoires d’expression cutanée : aspects moléculaires et cellulaires

Louvrier, C. (2019) · theses.fr (ABES) · doi:10.70675/ee57af23z15cdz4ec8zafebz9f9ac9f08220

Implication de l’inflammasome NLRP3 dans la détection des toxines bactériennes et dans l’évolution du COVID-19

Dufies, O. (2022) · theses.fr (ABES) · doi:10.70675/8c510881za1a9z4131zb1dbzbc9297f51b37

Rôle des flagelles dans la réponse inflammatoire au cours de l'infection par Clostridioides difficile

Chebly, H. (2022) · theses.fr (ABES) · doi:10.70675/5781ec34ze463z498cza414z0d3a4e3c2a22

Inflammation, aging and chronic diseases : implication of inflammasomes

Guerville, F. (2023) · theses.fr (ABES) · doi:10.70675/eac3286czda71z4606z9c90z3d3efeaf1afe

Implication de l'axe C5a-C5aR1 dans l'orage inflammatoire des formes sévères de COVID-19 de l'adulte

Carvelli, J. (2023) · theses.fr (ABES) · doi:10.70675/be12640bzc919z4322zb146z5a584bd7ec67

Unveiling the influence of Naftidrofuryl against lipopolysaccharide-induced lung injury model: Insights into inflammatory pathways

Bahashwan, A. S., El‐Shoura, E. A. M., Saad, ‏. M., & Zaafar, D. K. (2026) · The American Journal of the Medical Sciences · doi:10.1016/j.amjms.2026.04.003

A cell-death protein has an unexpected role in intestinal repair

Yisimayi, A., & Lieberman, J. (2026) · Nature · doi:10.1038/d41586-026-00810-7

The interplay of genetics and modifiable risk in atherosclerosis

Schunkert, H. (2026) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2026.120727

Ferroptosis is executed through caspase-5 cleavage of gasdermin E in ovarian cancer cellsPreprint

Akter, M., Sun, L., Chi, C., Hyder, I., Fu, Z., Jin, L., & Huang, S. (2026) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.64898/2026.06.15.732352

Advances of Caspase-11 for veterinary respiratory infections

Su, Y., Abi, K.-M., Gu, Q., Yang, F., & Zhao, G. (2026) · Frontiers in Veterinary Science · doi:10.3389/fvets.2026.1891521

Unconventional Protein Secretion in the Central Nervous System: Mechanisms and Roles in Physiology and Disease

Krauklis, S. A., Keceli, S. K., Campbell, E. M., & Abbineni, P. S. (2026) · Journal of Neurochemistry · doi:10.1111/jnc.70532

Cell-autonomous immunity as an integrated immune network against bacterial and viral pathogens

Martín-González, L., Ramos, B., Huang, Y., Thurston, T. L. M., Towers, G. J., & Lobato‐Márquez, D. (2026) · Nature Microbiology · doi:10.1038/s41564-026-02428-x

Regulation of inflammation by oxidized lipids

Gioia, M. D., & Zanoni, I. (2026) · Science Immunology · doi:10.1126/sciimmunol.adv9397

Ferroptosis is executed through caspase-5 cleavage of gasdermin E in ovarian cancer cellsPreprint

Akter, M., Sun, L., Chi, C., Hyder, I., Fu, Z., Jin, L., & Huang, S. (2026) · eLife · doi:10.7554/elife.112266.1

Ferroptosis is executed through caspase-5 cleavage of gasdermin E in ovarian cancer cellsPreprint

Akter, M., Sun, L., Chi, C., Hyder, I., Fu, Z., Jin, L., & Huang, S. (2026) · eLife · doi:10.7554/elife.112266

To Die or Not to Die: How Sublethal Damage Rewires Cell Fate and Implications for Sepsis

Hu, Z., Zhou, X., Sun, Q., Jiang, L., Wu, M., Xie, J., Yang, Y., & Peng, F. (2026) · Journal of Inflammation Research · doi:10.2147/jir.s629930

When folding CARDs wins the game: molecular snapshots of lipopolysaccharide sensing by the non-canonical inflammasome

Began, J., & Brož, P. (2026) · Biochemical Society Transactions · doi:10.1042/bst20260715

The phosphate exporter XPR1 promotes gasdermin D–independent mature IL-1β secretion

Rémy, N., Six, C., Tury, S., SCHAFTINGEN, E. V., Battini, J., Lucas, S., Coulie, P. G., & Gomard, T. (2026) · Journal of Biological Chemistry · doi:10.1016/j.jbc.2026.113547

Pyroptosis-related pathways and their impact on immune microenvironment remodeling in pediatric ovarian and adnexal tumors

Sun, C., Zhang, L., Li, X., Liu, C., Zhou, Q., & Su, Y. (2026) · Experimental Cell Research · doi:10.1016/j.yexcr.2026.115177

Ferroptosis–Pyroptosis Crosstalk in Spinal Cord Injury: Molecular Mechanisms, Emerging Connectors, and Staged Therapeutic Perspectives

Wang, C., Jin, Y., & Cai, W. (2026) · Journal of Molecular Neuroscience · doi:10.1007/s12031-026-02604-y

The gasdermin family: from pyroptosis mechanisms to therapeutic targets

Xu, W., Liu, S., Yu, Z., Shi, J., Yang, Y., & Shi, F. (2026) · Signal Transduction and Targeted Therapy · doi:10.1038/s41392-026-02867-2

A Novel Biofilm Amyloid Ligand for Caspase-11 Drives Hyperactivation in Dendritic CellsPreprint

Mintri, S., Hu, G., Mathur, A., Whiteman, L. M., Dinis, A., Le, B., Grando, K. C. M., Shumba, P., Rathinam, V. A. K., Lien, E., et al. (2026) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.64898/2026.09.29.755159

The Achilles’ heel of immune checkpoint blockade: Uncovering mechanisms of immune exclusion that drive resistance

Maranou, E. (2026) · UTUPub (University of Turku)

Exercise promotes host anti-infection activity through CNDP2 metabolite-mediated inflammasome hyperactivation

Qian, Y., Cheng, X., Liu, Q., Wang, C., Kong, C., Li, M., 耿向阳, Ai, L., Zhao, M., Wang, S., et al. (2026) · PLoS Pathogens · doi:10.1371/journal.ppat.1014554

Metabolic hallmarks of regulated cell death

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Immune activation in context

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By Capturing Inflammatory Lipids Released from Dying Cells, the Receptor CD14 Induces Inflammasome-Dependent Phagocyte Hyperactivation

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A caspaselike activity is triggered by LPS and is required for survival of human dendritic cells

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Distinct Licensing of IL-18 and IL-1b Secretion in Response to NLRP3 Inflammasome Activation

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Inflammatory caspases are innate immune receptors for intracellular LPS

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