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Deciphering the Pyroptosis-Related Prognostic Signature and Immune Cell Infiltration Characteristics of Colon Cancer

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A detailed molecular network map and model of the NLRP3 inflammasome

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Vectorized Delivery of Alpha-GalactosylCeramide and Tumor Antigen on Filamentous Bacteriophage fd Induces Protective Immunity by Enhancing Tumor-Specific T Cell Response

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Pyroptosis Induction and Detection

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Interplay between Mitophagy and Inflammasomes in Neurological Disorders

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Macrophage priming is dispensable for NLRP3 inflammasome activation and restriction of Leishmania amazonensis replication

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AIBP controls TLR4 inflammarafts and mitochondrial dysfunction in a mouse model of Alzheimer’s disease

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New insights into the noncanonical inflammasome point to caspase-4 as a druggable target

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iNOS is necessary for GBP-mediated T. gondii clearance in murine macrophages via vacuole nitration and intravacuolar network collapse

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Noncanonical inflammasomes: Antimicrobial defense that does not play by the rules

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Atrial cardiomyocyte-restricted cleavage of gasdermin D promotes atrial arrhythmogenesis

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Versatility of gasdermin D beyond pyroptosis

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Targeting inflammasomes as an immunotherapeutic strategy for cancer

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DAMP signaling networks: from receptors to diverse pathophysiological functions

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Clinical development of cancer vaccines

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The central inflammasome adaptor protein ASC activates the inflammasome after transition from a soluble to an insoluble state

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Mesoporous sodium four-coordinate aluminosilicate nanoparticles modulate dendritic cell pyroptosis and activate innate and adaptive immunity

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The Therapeutic Potential of Pyroptosis in Melanoma

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Oxidized phospholipid damage signals as modulators of immunity

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Fiction and Facts about BCG Imparting Trained Immunity against COVID-19

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Functional Interplay between Methyltransferases and Inflammasomes in Inflammatory Responses and Diseases

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Cleavage-Mediated Regulation of Myd88 Signaling by Inflammasome-Activated Caspase-1

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Bucket lists must be completed during cell death

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Structural and mechanistic elucidation of inflammasome signaling by cryo-EM

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Natterin an aerolysin-like fish toxin drives IL-1β-dependent neutrophilic inflammation mediated by caspase-1 and caspase-11 activated by the inflammasome sensor NLRP6

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Great balls of fire: activation and signalling of inflammatory caspases

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Alendronate augments lipid A-induced IL-1β release and Smad3/NLRP3/ASC-dependent cell death

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Gasdermin Pore Forming Activities that Promote Inflammation from Living and Dead Cells

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ABCA1 deficiency contributes to podocyte pyroptosis priming via the APE1/IRF1 axis in diabetic kidney disease

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Induction of Trained Immunity by Recombinant Vaccines

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Imaging Approaches to Monitor Inflammasome Activation

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Gasdermins and cancers

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Inflammasomes and Cardiovascular Disease: Linking Inflammation to Cardiovascular Pathophysiology

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Human cytomegalovirus infection triggers a paracrine senescence loop in renal epithelial cells

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Blocking TIR Domain Interactions in TLR9 Signaling

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First International Precision Vaccines Conference: Multidisciplinary Approaches to Next-Generation Vaccines

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The neutrophil inflammasome

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Inflammasome Activation and Neutrophil Extracellular Traps in Atherosclerosis

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Mitochondrial DNA in Exercise-Mediated Innate Immune Responses

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Gasdermin D‐independent release of interleukin‐1β by living macrophages in response to mycoplasmal lipoproteins and lipopeptides

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A highly conserved host lipase deacylates oxidized phospholipids and ameliorates acute lung injury in mice

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Activation, Amplification, and Ablation as Dynamic Mechanisms of Dendritic Cell Maturation

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Inflammasome activation by SARS-CoV-2 and its participation in COVID-19 exacerbation

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NLRP3 inflammasome activation and symptom burden in KRAS-mutated CMML patients is reverted by IL-1 blocking therapy

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The Role of the NLRP3 Inflammasome in the Molecular and Biochemical Mechanisms of Cervical Ripening: A Comprehensive Review

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Obesity Causes Abrupt Changes in the Testicular Microbiota and Sperm Motility of Zebrafish

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Cigarette smoke promotes inflammasome‐independent activation of caspase‐1 and ‐4 leading to gasdermin D cleavage in human macrophages

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Guidelines for mouse and human DC functional assays

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To die or not to die: Gasdermins in intestinal health and disease

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The inflammasome pathway is activated by dengue virus non-structural protein 1 and is protective during dengue virus infection

Wong, M. P., Juan, E. Y. W., Chelluri, S. S., Wang, P., Pahmeier, F., Castillo-Rojas, B., Blanc, S. F., Biering, S. B., Vance, R. E., & Harris, E. (2024) · PLoS Pathogens · doi:10.1371/journal.ppat.1012167 · Cited by 17

Acute stress induces the rapid and transient induction of caspase-1, gasdermin D and release of constitutive IL-1β protein in dorsal hippocampus

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Discovery of a caspase cleavage motif antibody reveals insights into noncanonical inflammasome function

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Functions of IFNλs in Anti-Bacterial Immunity at Mucosal Barriers

Alphonse, N., Dickenson, R. E., Alrehaili, A., & Odendall, C. (2022) · Frontiers in Immunology · doi:10.3389/fimmu.2022.857639 · Cited by 16

CASP4/11 Contributes to NLRP3 Activation and COVID-19 Exacerbation

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Serum-borne lipids amplify TLR-activated inflammatory responses

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Post-influenza bacterial infection: mechanisms of pathogenesis and advances in therapeutic strategies

Lei, B., Wang, S., Yu, L., & Ma, Q. (2025) · Frontiers in Microbiology · doi:10.3389/fmicb.2025.1673643 · Cited by 15

Mutagenic Consequences of Sublethal Cell Death Signaling

Hawkins, C. J., & Miles, M. A. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22116144 · Cited by 15

Posttranslational Regulation of Inflammasomes, Its Potential as Biomarkers and in the Identification of Novel Drugs Targets

Nanda, S. K., Vollmer, S., & Pérez‐Oliva, A. B. (2022) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2022.887533 · Cited by 15

Targeting Multiple Homeostasis-Maintaining Systems by Ionophore Nigericin Is a Novel Approach for Senolysis

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Unmasking the NLRP3 inflammasome in dendritic cells as a potential therapeutic target for autoimmunity, cancer, and infectious conditions

Alipour, S., Mardi, A., Shajari, N., Kazemi, T., Sadeghi, M. R., Heris, J. A., Masoumi, J., & Baradaran, B. (2024) · Life Sciences · doi:10.1016/j.lfs.2024.122686 · Cited by 15

Ultraviolet-treated riboflavin alleviates atopic dermatitis by inhibiting NLRP3 inflammasome activation and M1 macrophage polarization via histone lactylation

Ge, S., Qiu, B., Liu, R., Sun, L., Yang, L., Chen, X., Tao, H., Yang, W., Yu, Y., & Wang, D. (2025) · Biochemical Pharmacology · doi:10.1016/j.bcp.2025.116879 · Cited by 15

Dissociation of TRIF bias and adjuvanticity

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Altered lung tissue lipidomic profile in caspase-4 positive non-small cell lung cancer (NSCLC) patients

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The colonic pathogen Entamoeba histolytica activates caspase-4/1 that cleaves the pore-forming protein gasdermin D to regulate IL-1β secretion

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Targeting the NLRP3 Inflammasome-Gasdermin D Axis to Combat Cardiovascular Diseases

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Gasdermins, Executors of Pyroptosis: A Decade in Perspective

Zhou, B., & Abbott, D. W. (2025) · Annual Review of Pathology Mechanisms of Disease · doi:10.1146/annurev-pathmechdis-042624-121548 · Cited by 14

The landscape of regulated cell death: It’s all downhill from here

Aufschnaiter, A., Oh, T., & Oberst, A. (2025) · Molecular Cell · doi:10.1016/j.molcel.2025.11.013 · Cited by 15

Inflammasomes as regulators of non-infectious disease

Okin, D. A., & Kagan, J. C. (2023) · Seminars in Immunology · doi:10.1016/j.smim.2023.101815 · Cited by 14

Epigenetic and transcriptional control of gasdermins

Cadena, C., Kornfeld, O. S., Lee, B. L., & Kayagaki, N. (2023) · Seminars in Immunology · doi:10.1016/j.smim.2023.101841 · Cited by 15

Adipose triglyceride lipase suppresses noncanonical inflammasome by hydrolyzing LPS

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Strategies of bacterial detection by inflammasomes

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Zinc Ion-Coordinated Sericin Calcium Phosphate Nanovaccines Induce Hyperactive Dendritic Cells and Synergistic Activation of T Cells for Cancer Immunotherapy

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Inflammasome involvement in CS-induced damage in HaCaT keratinocytes

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