The α v β 1 integrin plays a critical in vivo role in tissue fibrosis

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Items 101–200 of 314

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  3. Role of nuclear mechanosensitivity in determining cellular responses to forces and biomaterials
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  4. Diverse origins and activation of fibroblasts in cardiac fibrosis
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  5. Platelet-rich plasma: combinational treatment modalities for musculoskeletal conditions
    Isabel Andı́a, Michele Abate · 2017 · Frontiers of Medicine
  6. Matters of context guide future research in TGFβ superfamily signaling
    Akhurst, Rosemary J., Padgett, Richard W. · 2015 · Science Signaling
  7. Dendritic cells maintain dermal adipose–derived stromal cells in skin fibrosis
    Dennis J. Chia, Tong Zhu, Susan Chyou, Dragos Dasoveanu, Camila B. Carballo, Sha Tian, CYNTHIA M.J. MAGRO, Scott Alan Rodeo, Robert Spiera, Nancy H. Ruddle et al. · 2016 · Journal of Clinical Investigation
  8. Antifibrotics in chronic liver disease: tractable targets and translational challenges
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  10. A WISP1 antibody inhibits MRTF signaling to prevent the progression of established liver fibrosis
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  11. αvβ1 integrin is enriched in extracellular vesicles of metastatic breast cancer cells: A mechanism mediated by galectin‐3
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  13. Hitting the Target! Challenges and Opportunities for TGF-β Inhibition for the Treatment of Cardiac fibrosis
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  14. An integrin antagonist ( MK ‐0429) decreases proteinuria and renal fibrosis in the ZSF 1 rat diabetic nephropathy model
    Xiaoyan Zhou, Zhang Ji, Robin E. Haimbach, Wei Zhu, Rosemary Mayer‐Ezell, Margarita M. Garcia-Calvo, Elizabeth Smith, Olga Price, Yanqing Kan, Emanuel Zycband et al. · 2017 · Pharmacology Research & Perspectives
  15. Defining the mechanism of galectin-3–mediated TGF-β1 activation and its role in lung fibrosis
    J Calver, Nimesh R. Parmar, Gemma Harris, Ryan M. Lithgo, Panayiota Stylianou, Fredrik R. Zetterberg, Bibek Gooptu, Alison C. MacKinnon, Stephen B. Carr, Lee Anthony Borthwick et al. · 2024 · Journal of Biological Chemistry
  16. Interaction between Galectin-3 and Integrins Mediates Cell-Matrix Adhesion in Endothelial Cells and Mesenchymal Stem Cells
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  17. Emerging role for branched-chain amino acids metabolism in fibrosis
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  20. Ablation of integrin-mediated cell–collagen communication alleviates fibrosis
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  28. Anti-integrin αv therapy improves cardiac fibrosis after myocardial infarction by blunting cardiac PW1+ stromal cells
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  29. Does Breathing Amplify Fibrosis?
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  35. Spontaneous Extracellular Matrix Accumulation in a Human in vitro Model of Renal Fibrosis Is Mediated by αV Integrins
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  38. Inhibitors of Arg-Gly-Asp-Binding Integrins Reduce Development of Pancreatic Fibrosis in Mice
    Barbara Ulmasov, Brent A. Neuschwander‐Tetri, Jinping Lai, Vladimir Monastyrskiy, Trisha S. Bhat, Matthew P. Yates, Jonathan Oliva, Michael J. Prinsen, Peter Ruminski, David W. Griggs · 2016 · Cellular and Molecular Gastroenterology and Hepatology
  39. The deubiquitylase USP10 regulates integrin β1 and β5 and fibrotic wound healing
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  40. RGD‐binding integrins and TGF‐β in SARS‐CoV‐2 infections – novel targets to treat COVID‐19 patients?
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  42. Transforming growth factor-β plays divergent roles in modulating vascular remodeling, inflammation, and pulmonary fibrosis in a murine model of scleroderma
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  43. RGD-Binding Integrins in Head and Neck Cancers
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  49. Mitogen-activated Protein Kinase–activated Protein Kinase 2 Inhibition Attenuates Fibroblast Invasion and Severe Lung Fibrosis
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  50. Exploring Integrin α5β1 as a Potential Therapeutic Target for Pulmonary Arterial Hypertension: Insights From Comprehensive Multicenter Preclinical Studies
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  54. Integrin αVβ1 regulates procollagen I production through a non-canonical transforming growth factor β signaling pathway in human hepatic stellate cells
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  55. Deletion of β1-integrin in collecting duct principal cells leads to tubular injury and renal medullary fibrosis
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  56. The role of cytokine and immune responses in intestinal fibrosis
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  57. Understanding the role of structural integrity and differential expression of integrin profiling to identify potential therapeutic targets in breast cancer
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  58. Proteomic Profiling of Fibroblasts Isolated from Chronic Wounds Identifies Disease-Relevant Signaling Pathways
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