GABA A receptor availability is not altered in adults with autism spectrum disorder or in mouse models
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There are no alterations in GABA A receptor availability in adults with autism spectrum disorder or in commonly used rodent models of the condition.
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- Authors
- Horder, J., Andersson, M., Mendez, M. A., Singh, N., Tangen, Ä., Lundberg, J., Gee, A., Halldin, C., Veronese, M., Bölte, S., Farde, L., Sementa, T., Cash, D., Higgins, K., Spain, D., Turkheimer, F., Mick, I., Selvaraj, S., Nutt, D. J., Lingford-Hughes, A., Howes, O. D., Murphy, D. G., & Borg, J.
- Affiliations
- King's College London (GB)
- Region Stockholm (SE)
- Department of Forensic and Neurodevelopmental Sciences and Sackler Institute for Translational Neurodevelopment, Institute of Psychiatry, Psychology and Neuroscience, King’s College London, London, UK.
- Imperial College London (GB)
- Corresponding author
- Horder, Jamie
- Andersson, Max
- Murphy, Declan G.
- Borg, Jacqueline
- ORCID
- Horder, Jamie
- Andersson, Max
- Mendez, Maria A.
- Singh, Nisha
- Tangen, Ämma
- Lundberg, Johan
- Gee, Antony
- Halldin, Christer
- Veronese, Mattia
- Bölte, Sven
- Farde, Lars
- Sementa, Teresa
- Cash, Diana
- Higgins, Karen
- Spain, Debbie
- Turkheimer, Federico
- Mick, Inge
- Selvaraj, Sudhakar
- Nutt, David J.
- Lingford-Hughes, Anne
- Howes, Oliver D.
- Murphy, Declan G.
- Borg, Jacqueline
- Venue
- Science Translational Medicine
- Published
- 2018-10-03
- Volume
- 10
- Issue
- 461
- ISSN
- 1946-6234 (ISSN-L)
- 1946-6242
- OpenAlex
- W2884065692
- Cited by
- 60
- References
- 70
- Citations by year
- 2026: 5 · 2025: 7 · 2024: 2 · 2023: 8 · 2022: 9 · 2021: 10 · 2020: 12 · 2019: 7
- FWCI
- 4.32
- Type
- journal article
- Language
- en
- Open access
- green
- kclpure.kcl.ac.uk
- Licence
- other-oa
- Locations
- Science Translational Medicine (publishedVersion)
- PubMed (publishedVersion)
- eSpace (Curtin University) (submittedVersion)
- Research Portal (King's College London) (submittedVersion, other-oa)
- Spiral (Imperial College London) (submittedVersion)
- Padua Research Archive (University of Padova) (submittedVersion)
- Funders
- Wellcome Trust (091300/Z/10/Z)
- European Union (FP7/2007-2013)
- EU IMI (115300)
- Topics
- Life Sciences › Neuroscience › Cognitive Neuroscience › Autism Spectrum Disorder Research
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neuroscience and Neuropharmacology Research
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Genetics and Neurodevelopmental Disorders
- Keywords
- GABAA receptor, receptor availability, autism spectrum disorder, adults, brain receptor binding
- MeSH terms
- Autism Spectrum Disorder, Adult, Animals, Azides, Behavior, Benzodiazepines, Carbon Radioisotopes, Disease Models, Animal, Female, Flumazenil, Humans, Male, Motion Perception, Receptors, GABA-A, Task Performance and Analysis, Case-Control Studies, Protein Subunits, Positron-Emission Tomography, Mice, Gray Matter
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