Cited by 60Autism Spectrum Disorder ResearchNeuroscience and Neuropharmacology ResearchGenetics and Neurodevelopmental Disorders

GABA A receptor availability is not altered in adults with autism spectrum disorder or in mouse models

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Horder, Jamie, Andersson, Max, Mendez, Maria A., Singh, Nisha, Tangen, Ämma, Lundberg, Johan, Gee, Antony, Halldin, Christer +15 more·2018·Science Translational Medicine

Abstract

There are no alterations in GABA A receptor availability in adults with autism spectrum disorder or in commonly used rodent models of the condition.

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Crossref · 10.1126/scitranslmed.aam8434

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70 of 70 references verified0 citation errors · 0 not checkable

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Authors
Horder, J., Andersson, M., Mendez, M. A., Singh, N., Tangen, Ä., Lundberg, J., Gee, A., Halldin, C., Veronese, M., Bölte, S., Farde, L., Sementa, T., Cash, D., Higgins, K., Spain, D., Turkheimer, F., Mick, I., Selvaraj, S., Nutt, D. J., Lingford-Hughes, A., Howes, O. D., Murphy, D. G., & Borg, J.
Affiliations
  • King's College London (GB)
  • Region Stockholm (SE)
  • Department of Forensic and Neurodevelopmental Sciences and Sackler Institute for Translational Neurodevelopment, Institute of Psychiatry, Psychology and Neuroscience, King’s College London, London, UK.
  • Imperial College London (GB)
Corresponding author
  • Horder, Jamie
  • Andersson, Max
  • Murphy, Declan G.
  • Borg, Jacqueline
Venue
Science Translational Medicine
Published
2018-10-03
Volume
10
Issue
461
ISSN
  • 1946-6234 (ISSN-L)
  • 1946-6242
OpenAlex
W2884065692
Cited by
60
References
70
Citations by year
2026: 5 · 2025: 7 · 2024: 2 · 2023: 8 · 2022: 9 · 2021: 10 · 2020: 12 · 2019: 7
FWCI
4.32
Type
journal article
Language
en
Open access
Licence
other-oa
Locations
  • Science Translational Medicine (publishedVersion)
  • PubMed (publishedVersion)
  • eSpace (Curtin University) (submittedVersion)
  • Research Portal (King's College London) (submittedVersion, other-oa)
  • Spiral (Imperial College London) (submittedVersion)
  • Padua Research Archive (University of Padova) (submittedVersion)
Funders
  • Wellcome Trust (091300/Z/10/Z)
  • European Union (FP7/2007-2013)
  • EU IMI (115300)
Topics
  • Life Sciences › Neuroscience › Cognitive Neuroscience › Autism Spectrum Disorder Research
  • Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neuroscience and Neuropharmacology Research
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Genetics and Neurodevelopmental Disorders
Keywords
GABAA receptor, receptor availability, autism spectrum disorder, adults, brain receptor binding
MeSH terms
Autism Spectrum Disorder, Adult, Animals, Azides, Behavior, Benzodiazepines, Carbon Radioisotopes, Disease Models, Animal, Female, Flumazenil, Humans, Male, Motion Perception, Receptors, GABA-A, Task Performance and Analysis, Case-Control Studies, Protein Subunits, Positron-Emission Tomography, Mice, Gray Matter

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