Cited by 185Autism Spectrum Disorder ResearchNeuroendocrine regulation and behaviorGenetics and Neurodevelopmental Disorders

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A randomized placebo-controlled pilot trial shows that intranasal vasopressin improves social deficits in children with autism

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Parker, Karen J., Oztan, Ozge, Libove, Robin A., Mohsin, Noreen, Karhson, Debra S., Sumiyoshi, Raena D., Summers, Jacqueline E., Hinman, Kyle E., Motonaga, Kara S., Phillips, Jennifer M., Carson, Dean S., Fung, Lawrence K., Garner, Joseph P., Hardan, Antonio Y.·2019·Science Translational Medicine

DOI 10.1126/scitranslmed.aau7356PMC PMC6716148

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Abstract

Intranasal delivery of the neuropeptide vasopressin improves social abilities in children with autism spectrum disorder.

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Authors: Parker, K. J., Oztan, O., Libove, R. A., Mohsin, N., Karhson, D. S., Sumiyoshi, R. D., Summers, J. E., Hinman, K. E., Motonaga, K. S., Phillips, J. M., Carson, D. S., Fung, L. K., Garner, J. P., & Hardan, A. Y.
Affiliations: Stanford Medicine (US)
Corresponding author: Parker, Karen J.
ORCID: Parker, Karen J.
Oztan, Ozge
Mohsin, Noreen
Karhson, Debra S.
Sumiyoshi, Raena D.
Summers, Jacqueline E.
Hinman, Kyle E.
Motonaga, Kara S.
Phillips, Jennifer M.
Carson, Dean S.
Fung, Lawrence K.
Garner, Joseph P.
Hardan, Antonio Y.
Venue: Science Translational Medicine
Publisher: American Association for the Advancement of Science (AAAS)
Published: 2019-05-08
Volume: 11
Issue: 491
ISSN: 1946-6234 (ISSN-L)
1946-6242
DOI: 10.1126/scitranslmed.aau7356
PMC: PMC6716148
OpenAlex: W2943453749
Cited by: 185
References: 68
Citations by year: 2026: 22 · 2025: 21 · 2024: 23 · 2023: 29 · 2022: 42 · 2021: 27 · 2020: 14 · 2019: 7
FWCI: 13.08
Type: journal article
Language: en
Open access: green
www.ncbi.nlm.nih.gov
Locations: Science Translational Medicine (publishedVersion)
PubMed (publishedVersion)
PubMed Central (acceptedVersion)
Funders: National Institute of Mental Health (R21MH100387, T32MH019908, K08MH111750)
Autism Speaks (7895)
Eunice Kennedy Shriver National Institute of Child Health and Human Development (R21HD083629, R01HD091972)
Stanford’s Department of Psychiatry (N/A)
The Teresa and Charles Michael Endowed Fund for Autism Research and Education (N/A)
The Child Health Research Institute (N/A)
The Yani Calmidis Memorial Fund for Autism Research (N/A)
Mosbacher Family Fund for Autism Research (N/A)
Bass Society (N/A)
Topics: Life Sciences › Neuroscience › Cognitive Neuroscience › Autism Spectrum Disorder Research
Life Sciences › Neuroscience › Endocrine and Autonomic Systems › Neuroendocrine regulation and behavior
Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Genetics and Neurodevelopmental Disorders
Keywords: autism spectrum disorder, social dysfunction, children, anxiety symptoms, repetitive behavior, treatment tolerability, adverse events
MeSH terms: Autism Spectrum Disorder, Administration, Intranasal, Child, Female, Humans, Male, Pilot Projects, Placebos, Social Behavior, Vasopressins, Treatment Outcome

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A randomized placebo-controlled pilot trial shows that intranasal vasopressin improves social deficits in children with autism

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