Cited by 165Phytoestrogen effects and researchGut microbiota and healthProbiotics and Fermented Foods

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Isolation of a Human Intestinal Bacterium Capable of Daidzein and Genistein Conversion

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Matthies, Anastasia, Blaut, Michael, Braune, Annett·2009·Applied and Environmental Microbiology

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Abstract

A rod-shaped gram-positive anaerobic bacterium, strain HE8, was isolated from human feces. The isolate was able to convert the isoflavones daidzein and genistein to equol and 5-hydroxy-equol, respectively. Based on phenotypic and phylogenetic analyses, strain HE8 is described as a new species, Slackia isoflavoniconvertens.

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Tree View: An application to display phylogenetic trees on personal computers
Page, R. (1996) · Computer applications in the biosciences · doi:10.1093/bioinformatics/12.4.357 · Cited by 10,223
Report of the Ad Hoc Committee on Reconciliation of Approaches to Bacterial Systematics
Wayne, L. G., Moore, W. E., Stackebrandt, E. S., Kandler, O., Colwell, R. R., Krichevsky, M. I., Trüper, H. G., Murray, R. G. E., Grimont, P. A. D., Brenner, D. J., et al. (1987) · INTERNATIONAL JOURNAL OF SYSTEMATIC AND EVOLUTIONARY MICROBIOLOGY · doi:10.1099/00207713-37-4-463 · Cited by 7,338
Precise Measurement of the G+C Content of Deoxyribonucleic Acid by High-Performance Liquid Chromatography
MESBAH, M., PREMACHANDRAN, U., & Whitman, W. B. (1989) · International Journal of Systematic Bacteriology · doi:10.1099/00207713-39-2-159 · Cited by 4,534
Dietary polyphenols and the prevention of diseases
Scalbert, A., Manach, C., Morand, C., Rémésy, C., & Jiménez, L. (2005) · Critical Reviews in Food Science and Nutrition · doi:10.1080/1040869059096 · Cited by 2,999
Multiple sequence alignment with Clustal X
Jeanmougin, F., Thompson, J. D., Gouy, M., Higgins, D. G., & Gibson, T. J. (1998) · Trends in Biochemical Sciences · doi:10.1016/s0968-0004(98)01285-7 · Cited by 2,652
The Quantitative Measurement of DNA Hybridization from Renaturation Rates
Ley, J. D., Cattoir, H., & Reynaerts, A. (1970) · European Journal of Biochemistry · doi:10.1111/j.1432-1033.1970.tb00830.x · Cited by 2,585
Determination of DNA base composition by reversed-phase high-performance liquid chromatography
Támaoka, J., & Komagata, K. (1984) · FEMS Microbiology Letters · doi:10.1111/j.1574-6968.1984.tb01388.x · Cited by 2,420
Studies on the spectrophotometric determination of DNA hybridization from renaturation rates
Huss, V. A. R., Festl, H., & Schleifer, K. H. (1983) · Systematic and Applied Microbiology · doi:10.1016/s0723-2020(83)80048-4 · Cited by 1,648
Sequence heterogeneities of genes encoding 16S rRNAs in Paenibacillus polymyxa detected by temperature gradient gel electrophoresis
Nübel, U., Engelen, B., Felske, A., Snaidr, J., Wieshuber, A., Amann, R., Ludwig, W., & Backhaus, H. (1996) · Journal of Bacteriology · doi:10.1128/jb.178.19.5636-5643.1996 · Cited by 1,356
Bioavailability and bioefficacy of polyphenols in humans. II. Review of 93 intervention studies
Williamson, G., & Manach, C. (2005) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/81.1.243s · Cited by 1,340

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Authors: Matthies, A., Blaut, M., & Braune, A.
Affiliations: German Institute of Human Nutrition (DE)
Department of Gastrointestinal Microbiology, German Institute of Human Nutrition Potsdam-Rehbruecke, Arthur-Scheunert-Allee 114-116, D-14558 Nuthetal, Germany
Corresponding author: Braune, Annett
ORCID: Matthies, Anastasia
Braune, Annett
Venue: Applied and Environmental Microbiology
Publisher: American Society for Microbiology
Published: 2009-03-15
Volume: 75
Issue: 6
Pages: 1740-1744
ISSN: 0099-2240 (ISSN-L)
1098-5336
DOI: 10.1128/aem.01795-08
PMC: PMC2655447
OpenAlex: W1992373112
Cited by: 161
References: 40
Citations by year: 2026: 6 · 2025: 2 · 2024: 12 · 2023: 11 · 2022: 16 · 2021: 13 · 2020: 12 · 2019: 9 · 2018: 9 · 2017: 8 · 2016: 9 · 2015: 12 · 2014: 12 · 2013: 9 · 2012: 5
FWCI: 5.40
Type: journal article
Language: en
Open access: green
www.ncbi.nlm.nih.gov
Licence: journals.asm.org/non-commercial-tdm-license (tdm)
Locations: Applied and Environmental Microbiology (publishedVersion)
PubMed Central (publishedVersion)
PubMed (publishedVersion)
Topics: Health Sciences › Nursing › Nutrition and Dietetics › Phytoestrogen effects and research
Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Gut microbiota and health
Life Sciences › Agricultural and Biological Sciences › Food Science › Probiotics and Fermented Foods
Keywords: daidzein, genistein, equol, human gut bacteria, anaerobic Gram-positive bacteria, novel bacterial species, isoflavone metabolism, human feces
MeSH terms: Aerobiosis, DNA, Bacterial, DNA, Ribosomal, Feces, Humans, Isoflavones, Molecular Sequence Data, Phylogeny, RNA, Bacterial, RNA, Ribosomal, 16S, Sequence Homology, Nucleic Acid, Sequence Analysis, DNA, Genistein, Genes, rRNA, Actinobacteria, Gastrointestinal Tract, Equol

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Isolation of a Human Intestinal Bacterium Capable of Daidzein and Genistein Conversion

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