Cited by 259Evolution and Genetic DynamicsViral Infections and Immunology ResearchGenomics and Phylogenetic Studies

The DOI matches its Crossref record; 44 of the 44 references it cites were found in a registry or an index.

Evidence of Recombination among Enteroviruses

Open access

Santti, Juhana, Hyypiä, Timo, Kinnunen, Leena, Salminen, Mika·1999·Journal of Virology

DOI 10.1128/jvi.73.10.8741-8749.1999PMC PMC112895

Open this paper in CoChat — free account

Abstract

Human enteroviruses consist of more than 60 serotypes, reflecting a wide range of evolutionary divergence. They have been genetically classified into four clusters on the basis of sequence homology in the coding region of the single-stranded RNA genome. To explore further the genetic relationships between human enteroviruses and to characterize the evolutionary mechanisms responsible for variation, previously sequenced genomes were subjected to detailed comparison. Bootstrap and genetic similarity analyses were used to systematically scan the alignments of complete genomic sequences. Bootstrap analysis provided evidence from an early recombination event at the junction of the 5′ noncoding and coding regions of the progenitors of the current clusters. Analysis within the genetic clusters indicated that enterovirus prototype strains include intraspecies recombinants. Recombination breakpoints were detected in all genomic regions except the capsid protein coding region. Our results suggest that recombination is a significant and relatively frequent mechanism in the evolution of enterovirus genomes.

Integrity signals

Registry

Crossref · 10.1128/jvi.73.10.8741-8749.1999

Cites

44 of 44 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

We couldn’t retrieve this paper’s full text, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice
Thompson, J. D., Higgins, D. G., & Gibson, T. J. (1994) · Nucleic Acids Research · doi:10.1093/nar/22.22.4673 · Cited by 64,617
CONFIDENCE LIMITS ON PHYLOGENIES: AN APPROACH USING THE BOOTSTRAP
Felsenstein, J. (1985) · Evolution · doi:10.1111/j.1558-5646.1985.tb00420.x · Cited by 44,791
PHYLIP-Phylogeny inference package (Version 3.2)
Felsenstein, J. (1989) · Cladistics · Cited by 17,682
Full-Length Human Immunodeficiency Virus Type 1 Genomes from Subtype C-Infected Seroconverters in India, with Evidence of Intersubtype Recombination
Lole, K. S., Bollinger, R. C., Paranjape, R., Gadkari, D. A., Kulkarni, S., Novak, N. G., Ingersoll, R., Sheppard, H. W., & Ray, S. C. (1999) · Journal of Virology · doi:10.1128/jvi.73.1.152-160.1999 · Cited by 2,700
Cellular receptor for poliovirus: Molecular cloning, nucleotide sequence, and expression of a new member of the immunoglobulin superfamily
Mendelsohn, C. L., Wimmer, E., & Racaniello, V. R. (1989) · Cell · doi:10.1016/0092-8674(89)90690-9 · Cited by 1,116
Identification of Breakpoints in Intergenotypic Recombinants of HIV Type 1 by Bootscanning
Salminen, M. O., Carr, J. K., Burke, D. S., & McCutchan, F. E. (1995) · AIDS Research and Human Retroviruses · doi:10.1089/aid.1995.11.1423 · Cited by 876
Self-citation
Rates of spontaneous mutation among RNA viruses.
Drake, J. W. (1993) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.90.9.4171 · Cited by 730
Recombination in HIV-1
Robertson, D. L., Sharp, P. M., McCutchan, F. E., & Hahn, B. H. (1995) · Nature · doi:10.1038/374124b0 · Cited by 562
Origin and Evolution of Viruses
Holland, J. J., & Domingo, E. (1998) · Virus Genes · doi:10.1023/a:1007989407305 · Cited by 524
The mechanism of RNA recombination in poliovirus
Kirkegaard, K., & Baltimore, D. (1986) · Cell · doi:10.1016/0092-8674(86)90600-8 · Cited by 499

Show all 44 references

Research works printed but not linked: 1

King A. M. Q. Brown F. Christian P. Hovi T. Hyypiä T. Knowles N. J. Lemon S. M. Minor P. D. Palmenberg A. C. Skern T. Stanway G. Picornaviridae Virus taxonomy. Seventh report of the International Committee on Taxonomy of Viruses. van Regenmortel M. H. V. Fauquet C. M. Bishop D. H. L. Carsten E. B. Estes M. K. Lemon S. M. Maniloff J. Mayo M. A. McGeoch D. J. Pringle C. R. Wickner R. B. 1999 996 Academic Press San Diego Calif

Sorted by citations

Genetic diversity and evolution of hepatitis C virus – 15 years on
Peter Simmonds, K. (2004) · Journal of General Virology · doi:10.1099/vir.0.80401-0 · Cited by 863
Consequences of Recombination on Traditional Phylogenetic Analysis
Schierup, M. H., & Hein, J. (2000) · Genetics · doi:10.1093/genetics/156.2.879 · Cited by 597
An emerging recombinant human enterovirus 71 responsible for the 2008 outbreak of Hand Foot and Mouth Disease in Fuyang city of China
Zhang, Y., Zhu, Z. H., Yang, W., Ren, J., Tan, X., Wang, Y., Mao, N., Xu, L., Zhu, S., Cui, A., et al. (2010) · Virology Journal · doi:10.1186/1743-422x-7-94 · Cited by 459
Phylogenetic Analysis of the Complete Genome of 18 Norwalk-like Viruses
Katayama, K., Shirato, H., Kojima, S., Kageyama, T., Oka, T., Hoshino, F. B., Fukushi, S., Shinohara, M., Uchida, K., Suzuki, Y., et al. (2002) · Virology · doi:10.1006/viro.2002.1568 · Cited by 315
Enterovirus 68 is associated with respiratory illness and shares biological features with both the enteroviruses and the rhinoviruses
Oberste, M. S., Maher, K., Schnurr, D. P., Flemister, M. R., Lovchik, J. C., Peters, H., Sessions, W. M., Kirk, C. J., Chatterjee, N. K., Fuller, S., et al. (2004) · Journal of General Virology · doi:10.1099/vir.0.79925-0 · Cited by 310
Frequency and Dynamics of Recombination within Different Species of Human Enteroviruses
Peter Simmonds, K., & Welch, J. (2005) · Journal of Virology · doi:10.1128/jvi.80.1.483-493.2006 · Cited by 269
Evidence for Frequent Recombination within SpeciesHuman Enterovirus BBased on Complete Genomic Sequences of All Thirty-Seven Serotypes
Oberste, M. S., Maher, K., & Pallansch, M. A. (2003) · Journal of Virology · doi:10.1128/jvi.78.2.855-867.2004 · Cited by 258
Human enterovirus 71 and hand, foot and mouth disease
Wong, S. S. Y., Yip, C. C., Lau, S. K. P., & Yuen, K. (2010) · Epidemiology and Infection · doi:10.1017/s0950268809991555 · Cited by 248
Role of recombination in evolution of enteroviruses
Lukashev, A. N. (2004) · Reviews in Medical Virology · doi:10.1002/rmv.457 · Cited by 224
Recombination and selection in the evolution of picornaviruses and other mammalian positive-stranded rna viruses
Simmonds, P. (2006) · Journal of Virology · doi:10.1128/jvi.01076-06 · Cited by 204
Complete genome sequences of all members of the species Human enterovirus A
Oberste, M. S., Peñaranda, S., Maher, K., & Pallansch, M. A. (2004) · Journal of General Virology · doi:10.1099/vir.0.79789-0 · Cited by 196
Human parechoviruses: Biology, epidemiology and clinical significance
Harvala, H., & Peter Simmonds, K. (2009) · Journal of Clinical Virology · doi:10.1016/j.jcv.2009.03.009 · Cited by 197
Rhinoviruses and Respiratory Enteroviruses: Not as Simple as ABC
Royston, L., & Tapparel, C. (2016) · Viruses · doi:10.3390/v8010016 · Cited by 215
Kobuviruses—A Comprehensive Review
Reuter, G., Boros, Á., & Pankovics, P. (2011) · Reviews in Medical Virology · doi:10.1002/rmv.677 · Cited by 188
Recombination in circulating Human enterovirus B: independent evolution of structural and non-structural genome regions
Lukashev, A. N., Lashkevich, V. A., Ivanova, O. E., Koroleva, G. A., Hinkkanen, A., & Ilonen, J. (2005) · Journal of General Virology · doi:10.1099/vir.0.81264-0 · Cited by 173
Recombination in circulating enteroviruses
Lukashev, A. N., Lashkevich, V. A., Ivanova, O. E., Koroleva, G. A., Hinkkanen, A. E., & Ilonen, J. (2003) · Journal of Virology · doi:10.1128/jvi.77.19.10423-10431.2003 · Cited by 170
Hepatitis A virus: Host interactions, molecular epidemiology and evolution
Vaughan, G., Rossi, L. M. G., Forbi, J. C., de Paula, V. S., Purdy, M. A., Xia, G., & Khudyakov, Y. E. (2013) · Infection Genetics and Evolution · doi:10.1016/j.meegid.2013.10.023 · Cited by 174
Enteroviruses 76, 89, 90 and 91 represent a novel group within the species Human enterovirus A
Oberste, M. S., Maher, K., Michele, S. M., Belliot, G., Uddin, M., & Pallansch, M. A. (2005) · Journal of General Virology · doi:10.1099/vir.0.80475-0 · Cited by 167
Genetic variability of hepatitis A virus
Costa‐Mattioli, M., Napoli, A. D., Ferré, V., Billaudel, S., Pérez-Bercoff, R., & Cristina, J. (2003) · Journal of General Virology · doi:10.1099/vir.0.19532-0 · Cited by 165
Human enterovirus 71 epidemics: what's next?
Yip, C., Lau, S., Woo, P. C. Y., & Yuen, K. Y. (2013) · Emerging Health Threats Jour · doi:10.3402/ehtj.v6i0.19780 · Cited by 153
Latest Developments in Gene Transfer Technology: Achievements, Perspectives, and Controversies over Therapeutic Applications
Romano, G., Micheli, P., Pacilio, C., & Giordano, A. (2000) · Stem Cells · doi:10.1634/stemcells.18-1-19 · Cited by 150
Circulation of type 1 vaccine-derived poliovirus in the philippines in 2001
Shimizu, H., Thorley, B., Paladin, F. J., Brussen, K. A., Stambos, V., Yuen, L., Utama, A., Tano, Y., Arita, M., Yoshida, H., et al. (2004) · Journal of Virology · doi:10.1128/jvi.78.24.13512-13521.2004 · Cited by 146
Genetic evolution of enterovirus 71: epidemiological and pathological implications
Bible, J. M., Pantelidis, P., Chan, P. K. S., & Tong, C. Y. W. (2007) · Reviews in Medical Virology · doi:10.1002/rmv.538 · Cited by 144
Evolution of the genome of Human enterovirus B: incongruence between phylogenies of the VP1 and 3CD regions indicates frequent recombination within the species
Lindberg, A., Andersson, P. O., Savolainen, C., Mulders, M. N., & Hovi, T. (2003) · Journal of General Virology · doi:10.1099/vir.0.18971-0 · Cited by 142
Evidence for recombination in natural populations of dengue virus type 1 based on the analysis of complete genome sequences
Tolou, H. J., Couissinier‐Paris, P., Durand, J. P., Mercier, V., Pina, J.-J. D., de Micco, P., Billoir, F., Charrel, R. N., & de Lamballerie, X. N. (2001) · Journal of General Virology · doi:10.1099/0022-1317-82-6-1283 · Cited by 139
A Distinct Group of Hepacivirus/Pestivirus-Like Internal Ribosomal Entry Sites in Members of Diverse Picornavirus Genera: Evidence for Modular Exchange of Functional Noncoding RNA Elements by Recombination
Hellen, C. U. T., & de Breyne, S. (2007) · Journal of Virology · doi:10.1128/jvi.02403-06 · Cited by 138
Analysis of a New Human Parechovirus Allows the Definition of Parechovirus Types and the Identification of RNA Structural Domains
Al-Sunaidi, M., Williams, Ç. H., Hughes, P. J., Schnurr, D. P., & Stanway, G. (2006) · Journal of Virology · doi:10.1128/jvi.00584-06 · Cited by 137
The Association of Recombination Events in the Founding and Emergence of Subgenogroup Evolutionary Lineages of Human Enterovirus 71
Leitch, E. C. M., Cabrerizo, M., Cardosa, J., Harvala, H., Ivanova, O. E., Koike, S., Kroes, A. C. M., Lukashev, A. N., Perera, D., Roivainen, M., et al. (2011) · Journal of Virology · doi:10.1128/jvi.06065-11 · Cited by 137
RNA Recombination Plays a Major Role in Genomic Change during Circulation of Coxsackie B Viruses
Oberste, M. S., Peñaranda, S., & Pallansch, M. A. (2004) · Journal of Virology · doi:10.1128/jvi.78.6.2948-2955.2004 · Cited by 137
Evidence of intratypic recombination in natural populations of hepatitis C virus
Colina, R., Casañe, D., Vásquez, S., García, L., Chunga, A., Romero, H., Khan, B., & Cristina, J. (2004) · Journal of General Virology · doi:10.1099/vir.0.19472-0 · Cited by 136
Recombination between Poliovirus and Coxsackie A Viruses of Species C: A Model of Viral Genetic Plasticity and Emergence
Combelas, N., Holmblat, B., Joffret, M.-L., Colbère-Garapin, F., & Delpeyroux, F. (2011) · Viruses · doi:10.3390/v3081460 · Cited by 135
Genetic variability and molecular evolution of Hepatitis A virus
Cristina, J., & Costa‐Mattioli, M. (2007) · Virus Research · doi:10.1016/j.virusres.2007.01.005 · Cited by 135
Enterovirus 68 among Children with Severe Acute Respiratory Infection, the Philippines
Imamura, T. (2011) · Emerging infectious diseases · doi:10.3201/eid1708.101328 · Cited by 134
Molecular Evolution of Puumala Hantavirus
Sironen, T. A., Vaheri, A. I., & Plyusnin, A. (2001) · Journal of Virology · doi:10.1128/jvi.75.23.11803-11810.2001 · Cited by 132
Diseases Caused by Enterovirus 71 Infection
Lee, T.-C., Guo, H., Su, H.-J. J., Yang, Y., Chang, H.-L., & Chen, K. (2009) · The Pediatric Infectious Disease Journal · doi:10.1097/inf.0b013e3181a41d63 · Cited by 131
Human Enterovirus 109: a Novel Interspecies Recombinant Enterovirus Isolated from a Case of Acute Pediatric Respiratory Illness in Nicaragua
Yozwiak, N. L., Skewes-Cox, P., Gordon, A. L., SABORÍO, S. I., Kuan, G. M., Balmaseda, Á., Ganem, D., Harris, E., & DeRisi, J. L. (2010) · Journal of Virology · doi:10.1128/jvi.00698-10 · Cited by 129
Molecular identification of new picornaviruses and characterization of a proposed enterovirus 73 serotype
Oberste, M. S., Schnurr, D. P., Maher, K., Busaidy, S. S. A., & Pallansch, M. A. (2001) · Journal of General Virology · doi:10.1099/0022-1317-82-2-409 · Cited by 131
Molecular typing and epidemiology of enteroviruses identified from an outbreak of aseptic meningitis in Belgium during the summer of 2000
Thoelen, I., Lemey, P., van der Donck, I., Beuselinck, K., Lindberg, A., & Ranst, M. A. V. (2003) · Journal of Medical Virology · doi:10.1002/jmv.10412 · Cited by 129
Co-Circulation and Genomic Recombination of Coxsackievirus A16 and Enterovirus 71 during a Large Outbreak of Hand, Foot, and Mouth Disease in Central China
Liu, W., Wu, S., Xiong, Y., Li, T., Zhou, W. J., Yan, M., Qin, K., Liu, Y., & Wu, J. (2014) · PLoS ONE · doi:10.1371/journal.pone.0096051 · Cited by 126
Recombination in Enteroviruses, a Multi-Step Modular Evolutionary Process
Muslin, C., Kain, A. M., Bessaud, M., Blondel, B., & Delpeyroux, F. (2019) · Viruses · doi:10.3390/v11090859 · Cited by 132
Recombination among picornaviruses
Lukashev, A. N. (2010) · Reviews in Medical Virology · doi:10.1002/rmv.660 · Cited by 123
Recombination and the Molecular Clock
Schierup, M. H., & Hein, J. (2000) · Molecular Biology and Evolution · doi:10.1093/oxfordjournals.molbev.a026256 · Cited by 122
New Natural Intergenotypic (2/5) Recombinant of Hepatitis C Virus
Abravanel, F., Claudinon, J., Nicot, F., Dubois, M., Chapuy‐Regaud, S., Sauné, K., Pasquier, C., & Izopet, J. (2007) · Journal of Virology · doi:10.1128/jvi.02639-06 · Cited by 121
Recombination between Polioviruses and Co-Circulating Coxsackie A Viruses: Role in the Emergence of Pathogenic Vaccine-Derived Polioviruses
Jegouic, S., Joffret, M.-L., Blanchard, C., Riquet, F. B., Perret, C., Pelletier, I., Colbere-Garapin, F., Rakoto-Andrianarivelo, M., & Delpeyroux, F. (2009) · PLoS Pathogens · doi:10.1371/journal.ppat.1000412 · Cited by 116
Molecular Evolution of a Type 1 Wild-Vaccine Poliovirus Recombinant during Widespread Circulation in China
Liu, H.-M., Zheng, D.-P., Zhang, L.-B., Oberste, M. S., Pallansch, M. A., & Kew, O. M. (2000) · Journal of Virology · doi:10.1128/jvi.74.23.11153-11161.2000 · Cited by 119
Evolutionary Dynamics and Temporal/Geographical Correlates of Recombination in the Human Enterovirus Echovirus Types 9, 11, and 30
Leitch, E. C. M., Cabrerizo, M., Cardosa, J., Harvala, H., Ivanova, O. E., Kroes, A. C. M., Lukashev, A. N., Muir, P., Odoom, J. K., Roivainen, M., et al. (2010) · Journal of Virology · doi:10.1128/jvi.00783-10 · Cited by 117
Transmission networks and population turnover of echovirus 30
Leitch, E. C. M., Bendig, J., Cabrerizo, M., Cardosa, J., Hyypiä, T., Ivanova, O. E., Kelly, A., Kroes, A. C. M., Lukashev, A., MacAdam, A., et al. (2009) · Journal of Virology · doi:10.1128/jvi.02109-08 · Cited by 109
Phylogenetic evidence for inter-typic recombination in the emergence of human enterovirus 71 subgenotypes.
Yoke-Fun, C., & AbuBakar, S. (2006) · BMC Microbiology · doi:10.1186/1471-2180-6-74 · Cited by 107
Evidence of Recombination and Genetic Diversity in Human Rhinoviruses in Children with Acute Respiratory Infection
Huang, T., Wang, W., Bessaud, M., Ren, P., Sheng, J., Yan, H., Zhang, J., Lin, X., Wang, Y., Delpeyroux, F., et al. (2009) · PLoS ONE · doi:10.1371/journal.pone.0006355 · Cited by 107
Natural genetic recombination between co-circulating heterotypic enteroviruses
Oprisan, G., Combiescu, M., Guillot, S., Caro, V., Combiescu, A., Delpeyroux, F., & Crainic, R. (2002) · Journal of General Virology · doi:10.1099/0022-1317-83-9-2193 · Cited by 105
The Current Status of the Disease Caused by Enterovirus 71 Infections: Epidemiology, Pathogenesis, Molecular Epidemiology, and Vaccine Development
Chang, P., Chen, S.-C., & Chen, K. (2016) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph13090890 · Cited by 104
Direct identification of human enterovirus serotypes in cerebrospinal fluid by amplification and sequencing of the VP1 region
Leitch, E. C. M., Harvala, H., Robertson, I., Ubillos, I., Templeton, K. E., & Peter Simmonds, K. (2009) · Journal of Clinical Virology · doi:10.1016/j.jcv.2008.11.015 · Cited by 104
Phylogenetic designation of enterovirus 71 genotypes and subgenotypes using complete genome sequences
Chan, Y. F., Sam, I., & AbuBakar, S. (2009) · Infection Genetics and Evolution · doi:10.1016/j.meegid.2009.05.010 · Cited by 101
The phylogeny ofTurnip mosaic virus; comparisons of 38 genomic sequences reveal a Eurasian origin and a recent ‘emergence’ in east Asia
Tomimura, K., Gibbs, A. J., Jenner, C. E., Walsh, J. A., & Ohshima, K. (2003) · Molecular Ecology · doi:10.1046/j.1365-294x.2003.01881.x · Cited by 96
Prospective Identification of Enteroviruses Involved in Meningitis in 2006 through Direct Genotyping in Cerebrospinal Fluid
Mirand, A., Henquell, C., Archimbaud, C., Chambon, M., Charbonné, F., Peigue‐Lafeuille, H., & Bailly, J. (2007) · Journal of Clinical Microbiology · doi:10.1128/jcm.01020-07 · Cited by 95
Partitioning the Genetic Diversity of a Virus Family: Approach and Evaluation through a Case Study of Picornaviruses
Lauber, C., & Gorbalenya, A. E. (2012) · Journal of Virology · doi:10.1128/jvi.07173-11 · Cited by 88
Recombination among human non-polio enteroviruses: implications for epidemiology and evolution
Kyriakopoulou, Z., Pliaka, V., Amoutzias, G. D., & Markoulatos, P. (2014) · Virus Genes · doi:10.1007/s11262-014-1152-y · Cited by 95
Molecular epidemiology and evolution of coxsackievirus A9
Santti, J., Harvala, H., Kinnunen, L., & Hyypiä, T. (2000) · Microbiology · doi:10.1099/0022-1317-81-5-1361 · Cited by 91
Self-citation
Emergence of enterovirus 71 “double-recombinant” strains belonging to a novel genotype D originating from southern China: first evidence for combination of intratypic and intertypic recombination events in EV71
Yip, C. C., Lau, S. K. P., Zhou, B., Zhang, M., Tsoi, H., Chan, K., Chen, X., Woo, P. C. Y., & Yuen, K. (2010) · Archives of Virology · doi:10.1007/s00705-010-0722-0 · Cited by 90
Evidence of Recombination in the Norovirus Capsid Gene
Rohayem, J., Münch, J., & Rethwilm, A. (2005) · Journal of Virology · doi:10.1128/jvi.79.8.4977-4990.2005 · Cited by 89
The Structure of the Stemloop D Subdomain of Coxsackievirus B3 Cloverleaf RNA and Its Interaction with the Proteinase 3C
Ohlenschläger, O., Wöhnert, J., Bucci, E. M., Seitz, S., Häfner, S., Ramachandran, R., Zell, R., & Görlach, M. (2004) · Structure · doi:10.1016/j.str.2004.01.014 · Cited by 86
Methods for virus classification and the challenge of incorporating metagenomic sequence data
Peter Simmonds, K. (2014) · Journal of General Virology · doi:10.1099/jgv.0.000016 · Cited by 85
Cardiomyocyte apoptosis in experimental coxsackievirus B3 myocarditis.
Saraste, A., Arola, A., Vuorinen, T., Kytö, V., Kallajoki, M., Pulkki, K., Voipio-Pulkki, L., & Hyypiä, T. (2003) · Cardiovascular pathology · doi:10.1016/s1054-8807(03)00077-2 · Cited by 90
Molecular Phylogeny and Proposed Classification of the Simian Picornaviruses
Oberste, M. S., Maher, K., & Pallansch, M. A. (2002) · Journal of Virology · doi:10.1128/jvi.76.3.1244-1251.2002 · Cited by 82
Comprehensive full-length sequence analyses of human parechoviruses: diversity and recombination
Benschop, K., de Vries, M., Minnaar, R. P., Stanway, G., van der Hoek, L., Wolthers, K. C., & Peter Simmonds, K. (2009) · Journal of General Virology · doi:10.1099/vir.0.014670-0 · Cited by 83
Characterization of an Outbreak of Hand, Foot, and Mouth Disease in Nanchang, China in 2010
Liu, M. Y., Liu, W., Luo, J., Liu, Y., Yang, Z., Berman, H. F., & Wu, J. (2011) · PLoS ONE · doi:10.1371/journal.pone.0025287 · Cited by 82
Evolution and Emergence of Enteroviruses through Intra- and Inter-species Recombination: Plasticity and Phenotypic Impact of Modular Genetic Exchanges in the 5’ Untranslated Region
Muslin, C., Joffret, M., Pelletier, I., Blondel, B., & Delpeyroux, F. (2015) · PLoS Pathogens · doi:10.1371/journal.ppat.1005266 · Cited by 81
Genetic characterization of human coxsackievirus A6 variants associated with atypical hand, foot and mouth disease: a potential role of recombination in emergence and pathogenicity
Gaunt, E. R., Harvala, H., Österback, R., Sreenu, V. B., Thomson, E. C., Waris, M. E., & Peter Simmonds, K. (2015) · Journal of General Virology · doi:10.1099/vir.0.000062 · Cited by 81
Basic rationale, current methods and future directions for molecular typing of human enterovirus
Nasri, D., Bouslama, L., Pillet, S., Bourlet, T., Aouni, M., & Pozzetto, B. (2007) · Expert Review of Molecular Diagnostics · doi:10.1586/14737159.7.4.419 · Cited by 82
Genetics, Recombination and Clinical Features of Human Rhinovirus Species C (HRV-C) Infections; Interactions of HRV-C with Other Respiratory Viruses
Wisdom, A., Chmielewska, A., Leitch, E. C. M., Gaunt, E. R., Templeton, K. E., Harvala, H., & Peter Simmonds, K. (2009) · PLoS ONE · doi:10.1371/journal.pone.0008518 · Cited by 80
Recombination in Enteroviruses Is a Biphasic Replicative Process Involving the Generation of Greater-than Genome Length ‘Imprecise’ Intermediates
Lowry, K., Woodman, A., Cook, J., & Evans, D. J. (2014) · PLoS Pathogens · doi:10.1371/journal.ppat.1004191 · Cited by 80
Molecular comparison of echovirus 11 strains circulating in Europe during an epidemic of multisystem hemorrhagic disease of infants indicates that evolution generally occurs by recombination
Chevaliez, S., Szendrôi, A., Caro, V., Balanant, J., Guillot, S., Berencsi, G., & Delpeyroux, F. (2004) · Virology · doi:10.1016/j.virol.2004.04.026 · Cited by 77
Recombination in rabbit haemorrhagic disease virus: Possible impact on evolution and epidemiology
Forrester, N. L., Moss, S. R., Turner, S. L., Schirrmeier, H., & Gould, E. A. (2008) · Virology · doi:10.1016/j.virol.2008.03.023 · Cited by 77
Enterovirus 94, a proposed new serotype in human enterovirus species D
Smura, T., Junttila, N., Blomqvist, S., Norder, H., Kaijalainen, S., Paananen, A., Magnius, L. O., Hovi, T., & Roivainen, M. (2007) · Journal of General Virology · doi:10.1099/vir.0.82510-0 · Cited by 75
Enterovirus surveillance reveals proposed new serotypes and provides new insight into enterovirus 5′-untranslated region evolution
Smura, T., Blomqvist, S., Paananen, A., Vuorinen, T., Sobotová, Z., Buboviča, V., Ivanova, O. E., Hovi, T., & Roivainen, M. (2007) · Journal of General Virology · doi:10.1099/vir.0.82866-0 · Cited by 71
Recombination dynamics of human parechoviruses: investigation of type-specific differences in frequency and epidemiological correlates
Calvert, J., Chieochansin, T., Benschop, K., Leitch, E. C. M., Drexler, J. F., Grywna, K., Ribeiro, H. D. C., Drosten, C., Harvala, H., Poovorawan, Y., et al. (2010) · Journal of General Virology · doi:10.1099/vir.0.018747-0 · Cited by 73
New complete genome sequences of human rhinoviruses shed light on their phylogeny and genomic features
Tapparel, C., Junier, T., Gerlach, D., Cordey, S., Belle, S. V., Perrin, L. H., Zdobnov, E. M., & Kaiser, L. (2007) · BMC Genomics · doi:10.1186/1471-2164-8-224 · Cited by 72
Methods for virus classification and the challenge of incorporating metagenomic sequence data
Peter Simmonds, K. (2015) · Journal of General Virology · doi:10.1099/vir.0.000016 · Cited by 71
Appearance of intratypic recombination of enterovirus 71 in Taiwan from 2002 to 2005
Huang, S.-C., Hsu, Y.-W., Wang, H., Huang, S.-W., Kiang, D., Tsai, H., Wang, S.-M., Liu, C., Lin, K.-H., Su, I., et al. (2007) · Virus Research · doi:10.1016/j.virusres.2007.10.002 · Cited by 71
Recombinant Human Enterovirus 71
Chan, Y. F., & AbuBakar, S. (2004) · Emerging infectious diseases · doi:10.3201/eid1008.040059 · Cited by 68
Evidence of recombination in the capsid-coding region of type A foot-and-mouth disease virus
Tosh, C., Hemadri, D., & Sanyal, A. (2002) · Journal of General Virology · doi:10.1099/0022-1317-83-10-2455 · Cited by 65
Widespread recombination within human parechoviruses: analysis of temporal dynamics and constraints
Benschop, K., Williams, Ç. H., Wolthers, K. C., Stanway, G., & Peter Simmonds, K. (2008) · Journal of General Virology · doi:10.1099/vir.0.83498-0 · Cited by 64
Large-scale genomic analysis reveals recurrent patterns of intertypic recombination in human enteroviruses
Nikolaidis, M., Mimouli, K., Kyriakopoulou, Z., Tsimpidis, M., Tsakogiannis, D., Markoulatos, P., & Amoutzias, G. D. (2018) · Virology · doi:10.1016/j.virol.2018.10.006 · Cited by 65
Analysis of the Serotype and Genotype Correlation of VP1 and the 5′ Noncoding Region in an Epidemiological Survey of the Human Enterovirus B Species
Thoelen, I., Moës, E., Lemey, P., Mostmans, S., Wollants, E., Lindberg, A., Vandamme, A., & Ranst, M. A. V. (2004) · Journal of Clinical Microbiology · doi:10.1128/jcm.42.3.963-971.2004 · Cited by 64
Molecular typing of enteroviruses associated with viral meningitis in Cyprus, 2000–2002
Richter, J., Koptides, D., Tryfonos, C., & Christodoulou, C. (2006) · Journal of Medical Microbiology · doi:10.1099/jmm.0.46447-0 · Cited by 61
Recombination in uveitis-causing enterovirus strains
Lukashev, A. N., Lashkevich, V. A., Koroleva, G. A., Ilonen, J., & Hinkkanen, A. (2004) · Journal of General Virology · doi:10.1099/vir.0.19469-0 · Cited by 61
Emergence of recent echovirus 30 lineages is marked by serial genetic recombination events
Mirand, A., Henquell, C., Archimbaud, C., Peigue‐Lafeuille, H., & Bailly, J. (2006) · Journal of General Virology · doi:10.1099/vir.0.82146-0 · Cited by 59
Evidence of recombination in natural populations of hepatitis A virus
Costa‐Mattioli, M., Ferré, V., Casañe, D., Perez-Bercoff, R., Coste‐Burel, M., Imbert‐Marcille, B., Andre, E. C. M., Bressollette‐Bodin, C., Billaudel, S., & Cristina, J. (2003) · Virology · doi:10.1016/s0042-6822(03)00109-0 · Cited by 58
Novel serotypes 105 and 116 are members of distinct subgroups of Human enterovirus C
Lukashev, A. N., Drexler, J. F., Kotova, V. O., Амяга, Е. Н., Резник, В., Gmyl, A. P., Grard, G., Taty, R. T., Trotsenko, O. E., Leroy, E. M., et al. (2012) · Journal of General Virology · doi:10.1099/vir.0.043216-0 · Cited by 56
Molecular analysis of the echovirus 18 prototype
Andersson, P. O., Edman, K., & Lindberg, A. (2002) · Virus Research · doi:10.1016/s0168-1702(02)00019-9 · Cited by 57
Transfection‐mediated generation of functionally competent Tula hantavirus with recombinant S RNA segment
Plyusnin, A., Kukkonen, S. K. J., Plyusnina, A., Vapalahti, O. P., & Vaheri, A. I. (2002) · The EMBO Journal · doi:10.1093/emboj/21.6.1497 · Cited by 56
Genetic Relationship between Cocirculating Human Enteroviruses Species C
Bessaud, M., Joffret, M., Holmblat, B., Razafindratsimandresy, R., & Delpeyroux, F. (2011) · PLoS ONE · doi:10.1371/journal.pone.0024823 · Cited by 56
Molecular-based reclassification of the bovine enteroviruses
Zell, R., Krumbholz, A., Dauber, M., Hoey, E. M., & Wutzler, P. (2006) · Journal of General Virology · doi:10.1099/vir.0.81298-0 · Cited by 55
Evolution and conservation in human parechovirus genomes
Williams, Ç. H., Panayiotou, M., Girling, G., Peard, C. I., Oikarinen, S., Hyöty, H., & Stanway, G. (2009) · Journal of General Virology · doi:10.1099/vir.0.008813-0 · Cited by 55
Enterovirus A71: virulence, antigenicity, and genetic evolution over the years
Huang, S.-W., Cheng, D., & Wang, J. (2019) · Journal of Biomedical Science · doi:10.1186/s12929-019-0574-1 · Cited by 54
Coxsackieviruses and Quasispecies Theory: Evolution of Enteroviruses
Domingo, E., Martı́n, V., Perales, C., & Escarmı́s, C. (2008) · Springer eBooks · doi:10.1007/978-3-540-75546-3_1 · Cited by 54
Phylogenetic Patterns of Human Respiratory Picornavirus Species, Including the Newly Identified Group C Rhinoviruses, during a 1-Year Surveillance of a Hospitalized Patient Population in Italy
Piralla, A., Baldanti, F., & Gerna, G. (2010) · Journal of Clinical Microbiology · doi:10.1128/jcm.01814-10 · Cited by 51
Natural Recombination Event within the Capsid Genomic Region Leading to a Chimeric Strain of Human Enterovirus B
Bouslama, L., Nasri, D., Chollet, L., Belguith, K., Bourlet, T., Aouni, M., Pozzetto, B., & Pillet, S. (2007) · Journal of Virology · doi:10.1128/jvi.00180-07 · Cited by 51
Genetic Diversity of the Genus Cosavirus in the Family Picornaviridae: A New Species, Recombination, and 26 New Genotypes
Kapusinszky, B., Phan, T. G., Kapoor, A., & Delwart, E. (2012) · PLoS ONE · doi:10.1371/journal.pone.0036685 · Cited by 50
Dissemination of Internal Ribosomal Entry Sites (IRES) Between Viruses by Horizontal Gene Transfer
Arhab, Y., Bulakhov, A. G., Pestova, T. V., & Hellen, C. U. T. (2020) · Viruses · doi:10.3390/v12060612 · Cited by 45

Authors: Santti, J., Hyypiä, T., Kinnunen, L., & Salminen, M.
Affiliations: University of Turku (FI)
MediCity Research Laboratory and Department of Virology, University of Turku, FIN-20520 Turku,1
Department of Epidemiology and Health Promotion3 and
HIV Laboratory, Department of Infectious Disease Epidemiology,4National Public Health Institute, FIN-00300 Helsinki, Finland
ORCID: Kinnunen, Leena
Salminen, Mika
Venue: Journal of Virology
Publisher: American Society for Microbiology
Published: 1999-10
Volume: 73
Issue: 10
Pages: 8741-8749
ISSN: 0022-538X (ISSN-L)
1098-5514
DOI: 10.1128/jvi.73.10.8741-8749.1999
PMC: PMC112895
OpenAlex: W2130710544
Cited by: 259
References: 44
Citations by year: 2026: 6 · 2025: 5 · 2024: 16 · 2023: 2 · 2022: 2 · 2021: 4 · 2020: 5 · 2019: 3 · 2018: 6 · 2017: 5 · 2016: 7 · 2015: 8 · 2014: 16 · 2013: 14 · 2012: 16
FWCI: 3.89
Type: journal article
Language: en
Open access: green
www.ncbi.nlm.nih.gov
Licence: journals.asm.org/non-commercial-tdm-license (tdm)
Locations: Journal of Virology (publishedVersion)
Europe PMC (PubMed Central) (publishedVersion)
PubMed Central (publishedVersion)
PubMed (publishedVersion)
STM:n Hallinnonalan avoin julkaisuarkisto (Julkari) (submittedVersion)
Topics: Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Evolution and Genetic Dynamics
Health Sciences › Medicine › Infectious Diseases › Viral Infections and Immunology Research
Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Genomics and Phylogenetic Studies
Keywords: human enteroviruses, genetic recombination, viral evolution, enterovirus serotypes, recombination breakpoints, 5' untranslated region, single-stranded RNA genome, capsid protein, genetic groups
MeSH terms: Enterovirus, Humans, Recombination, Genetic, Genome, Viral, Evolution, Molecular

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Evidence of Recombination among Enteroviruses

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Citations

Cites

Cited by

Related

Metadata

Record

About these checks